Clinical trials: sponsored by University of Manitoba
Obesity, Bariatric Surgery
Does Participation in a Pre-Operative Physical Activity Program Improve Patient Outcomes and Quality of Life?
The primary objective of the study is to determine whether participation in a pre-bariatric surgery physical activity and behavior modification/education program (ENCOURAGEING START) that is tailored to the unique needs of obese…
- Conditions
- Obesity, Bariatric Surgery, Roux-En-Y Gastric Bypass, Exercise
- Trial name
- NCT03049696
- Testing
- ENCOURAGEING START
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- University of Manitoba
Sudden Infant Death
Evaluation of Safe Sleep for Babies: a Bassinet Distribution and Education Program
This study will evaluate baby box ownership and safe sleep practices (sleep location, sleep position, use of bedding) among families provided a free baby box and standardized safe sleep education compared to families provided a…
- Trial name
- NCT03392727
- Testing
- Study Box, Community Box, Education Session
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
DIEP Flap Breast Reconstruction, SIEA Flap Breast Reconstruction
Breast and Abdominal Related Morbidity of DIEP and SIEA Flaps
The Deep Inferior Epigastric Perforator flap (DIEP) is the current standard of care in breast reconstruction. The newer Superficial Inferior Epigastric Artery flap (SIEA) is felt to be an improvement as it does not damage the…
- Trial name
- NCT01469494
- Testing
- DIEP flap breast reconstruction, SIEA flap breast reconstruction
- Where
- Canada
- Volunteers
- 91 people
- Sponsor
- University of Manitoba
Stress Disorders, Post Traumatic, Anxiety
Preventing Post-traumatic Stress in ICU Survivors: A Pilot Randomized Controlled Trial of ICU Diaries
The main objective of the study is to test the feasibility of the ICU diaries intervention in the ICU. The investigators do not have sufficient power to detect differences in the hypotheses below, but will use the present pilot…
- Conditions
- Stress Disorders, Post Traumatic, Anxiety, Depression, Quality of Life
- Trial name
- NCT02067559
- Testing
- ICU Diary, Psychoeducation
- Where
- Canada
- Volunteers
- 59 people
- Sponsor
- University of Manitoba
Mechanical Ventilator Weaning
Assessment of Cough Strength in Patients With Tracheostomies
The investigators propose to assess cough strength in patients undergoing spontaneous breathing trials in the Intermediate Intensive Care Unit (IICU) and compare their cough strength under two conditions, 1.
- Trial name
- NCT02566512
- Testing
- Tracheostomy cuff inflation., Tracheostomy cuff deflation
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Surgical Wound Infection
Sutures Versus Staples for Wound Closure in Orthopaedic Surgery
The trial is a randomized, controlled trial. Adult patients undergoing orthopaedic surgical procedures would be randomized to one of two groups for surgical wound closure, skin sutures or skin staples.
- Trial name
- NCT01146236
- Testing
- Sutures, Staples
- Where
- 3 sites in Canada
- Volunteers
- 247 people
- Sponsor
- University of Manitoba
Delirium, Thoracic Surgery
Cerebral Oxygen Desaturation and Post-Operative Delirium in Thoracic Surgical Patients
This study will assess the incidence and risk factors for post-operative delirium in patients undergoing thoracotomy. Specifically, the study will assess if there is any relationship between an intra-operative decrease in brain…
- Trial name
- NCT03165539
- Testing
- Cerebral oxygen saturation monitoring
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University of Manitoba
Crohn Disease
The Efficacy of Denosumab in Active Crohn's Disease
Denosumab, a fully human monoclonal antibody to RANKL was approved for the treatment of postmenopausal osteoporosis in June 2010.
- Trial name
- NCT02321280
- Testing
- Denosumab
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- University of Manitoba
Obstructive Sleep Apnea Syndrome
Ketamine Infusion for Pediatric Patients With Obstructive Sleep Apnea Syndrome (OSAS) After Tonsillectomy
The study will evaluate the post-operative morphine-sparing effect, pain reduction, and side effects of a continuous ketamine infusion after tonsillectomy in pediatric patients.
- Trial name
- KOSATA (NCT02425202)
- Testing
- Ketamine, Saline infusion
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
IBD
Estimating Indirect and OOP Costs in Pediatric Inflammatory Bowel Disease: a National Study
inflammation of the gastrointestinal tract. A recent Canadian study from found that Canada has amongst highest incidence rates of childhood-onset IBD (10 per 100,000 for children <16y).
- Trial name
- NCT03522623
- Testing
- Non-interventional study
- Where
- Canada
- Volunteers
- 350 people
- Sponsor
- University of Manitoba
HIV Infection
Demonstrating Safety and Effective Delivery of Daily Oral Pre-exposure Prophylaxis (PrEP) for Sex Workers in India
Female sex workers (FSWs) in India are at high risk of HIV infection, and while correct and consistent condom use is an effective means of preventing HIV transmission, many FSWs have difficulty insisting on their use.
- Trial name
- PrEP-India (NCT02148094)
- Testing
- Truvada
- Where
- 2 sites in India
- Volunteers
- 1,325 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
D059350
A Trial of an Online Chronic Pain Treatment for Military, Police and Veterans
Chronic pain is a serious health issue in Canada. Individuals who experience chronic pain often find it difficult to attend in-person treatment sessions for a variety of reasons including pain flare-ups, discomfort when…
- Trial name
- NCT03287661
- Testing
- Acceptance-based Behavioural Therapy
- Where
- Canada
- Volunteers
- 29 people
- Sponsor
- University of Manitoba
Type 1 Diabetes
The VIGORous Physical Activity for Glycaemic Control in Type 1 Diabetes (VIGOR) Trial
Background/Justification: Regular physical activity (PA) has substantial health benefits in persons with type 1 diabetes (T1D), including reduced risk of complications and cardiovascular mortality.
- Trial name
- VIGOR (NCT01834144)
- Testing
- Exercise Training
- Where
- 5 sites in Canada
- Volunteers
- 4 people
- Sponsor
- University of Manitoba
Violence, Violence, Non-accidental
Optimization Study of the Wraparound Care for Youth Injured by Violence Program
This study is an optimization study to evaluate how a wraparound program for youth who have been injured by violence helps to change violence related attitudes and beliefs, change individual risk factors for violence and reduce…
- Conditions
- Violence, Violence, Non-accidental, Physical Violence
- Trial name
- NCT02573480
- Testing
- Wraparound care
- Where
- Canada
- Volunteers
- 11 people
- Sponsor
- University of Manitoba
Anxiety Disorders
Coaching for Confidence: Evaluating an Internet-based Program to Help Parents Help Children With Difficulty With Anxiety
The study is an open trial to evaluate a web-based intervention. The intervention focuses on supporting parents to help their children to overcome problems with anxiety.
- Trial name
- NCT02705261
- Testing
- cognitive-behavior therapy
- Where
- Canada
- Volunteers
- 92 people
- Sponsor
- University of Manitoba
Type 1 Diabetes
Determining the Appropriate Intensity of Exercise to Prevent Post-exercise Hypoglycemia in Persons Living With T1D
Over 300, 000 youth and young adults across Canada are living with Type 1 Diabetes (T1D) which is considered the most common endocrine condition.
- Trial name
- NCT03583268
- Testing
- Exercise
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of Manitoba
Colonoscopy, Bowel Preparation
Simethicone and Bowel Preparation in Colonoscopy
This Clinical Trial is being conducted to study the effect of oral simethicone on the presence of bubbles during colonoscopy. The purpose of this study is to find out what effects (good and bad) the addition of oral simethicone…
- Trial name
- NCT03157791
- Testing
- Simethicone 180Mg Cap
- Where
- Canada
- Volunteers
- 471 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Physical Inactivity, Low Physical Fitness
Effect of a Female Strength & Conditioning Specialist on High School Girls' Health
The majority of today's youth do not engage in enough physical activity (PA) to maintain good health. Low PA levels are associated with poor health (e.g. diabetes, high blood pressure) and early mortality.
- Trial name
- NCT02776579
- Testing
- Girls-only resistance training
- Where
- Canada
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Antibody Mediated Rejection
Cyclophosphamide Therapy for Refractory Antibody-Mediated Rejection (AMR) in Kidney Transplants
The study hypothesis is that short-term low dose cyclophosphamide therapy will be effective in resolving inflammation in patients with late phase antibody-mediated rejection refractory to current standard of care treatment.
- Trial name
- NCT01630538
- Testing
- Cyclophosphamide
- Where
- Canada
- Volunteers
- 4 people
- Sponsor
- University of Manitoba
Insomnia Chronic
Efficacy of Sleeping Without Pills (SWOP), an Online Drug Tapering Program
The aims of the study are to determine whether an online drug tapering program can lead to successful drug tapering in hypnotic dependent insomnia and whether such tapering is associated with improved daytime functioning and…
- Trial name
- NCT03194802
- Testing
- Sleeping Without Pills Program, Self-monitoring
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Manitoba