Clinical trials: sponsored by University of Manitoba
Infant, Premature, Diseases
Study the Safety and Efficacy of Probiotics Use in Premature Infants
Prophylactic enteral probiotics may enhance clinical markers and biomarkers of preterm infants' health, and may also play a role in reducing NEC and associated morbidity.
- Trial name
- NCT01891604
- Testing
- breast milk with Bifidobacterium Longum subp. Infantis R0033, breast milk
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Manitoba
Pain
Ultrasound-guided Supraclavicular Brachial Plexus Blockade
Pain Clinic patients undergoing physiotherapy for rehabilitation often have arm freezing performed. The quality of physiotherapy is felt to be superior with good pain control.
- Trial name
- NCT00523055
- Testing
- Lidocaine
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of Manitoba
Metabolism, Obesity
Finding the Optimal Voluntary Exercise Parameters for Those Living With Quadriplegia
There are over 44,000 persons living with spinal cord injury (SCI) in Canada, who face substantial challenges in maintaining a healthy body composition after injury.
- Conditions
- Metabolism, Obesity, Spinal Cord Injury
- Trial name
- NCT03146728
- Testing
- exercise
- Where
- Canada
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Hyperlipidemia
Genetic Basis for Heterogeneity in Response of Plasma Lipids to Plant Sterols
The substantial range of individual responsiveness to plant sterols has important ramifications. Marked differences across individuals in particular aspects of the cholesterol metabolic pathway must alter the impact of plant…
- Trial name
- NCT01131832
- Testing
- Plant sterol
- Where
- 2 sites in United States, Canada
- Volunteers
- 71 people
- Sponsor
- University of Manitoba
Spinal Cord Injury
Combined Tactile and Proprioception Training After Spinal Cord Injury
A novel rehabilitation bike has been developed for patients with incomplete spinal cord injuries that incorporates mechanical stimulators on the bike pedals to stimulate the sensory receptors in the soles of the feet; the effect…
- Trial name
- NCT02554058
- Testing
- Cycling and Mechanical stimulation
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of Manitoba
Wounds and Injuries
Strength Training for Injury Prevention
The purpose of this study is to explore the effects of a strength \& conditioning (S \& C) program on risk factors for injury (Y-balance and Functional Movement Screen scores), as well as parent reported injury occurrence in…
- Trial name
- NCT02927418
- Testing
- Strength & Conditioning, Control
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
IBD
Identifying a Sleep Screener for Disease Relapse in Children With Inflammatory Bowel Disease
Background: Inflammatory bowel disease (IBD) is a group of disorders characterized by chronic inflammation of the gastrointestinal tract with remissions and relapses.
- Trial name
- NCT02970149
- Testing
- NA (observational)
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- University of Manitoba
Diaphragmatic Function, Lung Function
Pulmonary Function Changes and Diaphragmatic Paralysis Following Ultrasound Guided Supraclavicular Brachial Plexus Blockade: The Effects of Decreased Local Anesthetic Volume
This clinical trial is being conducted to study lung function and movement of the major muscle involved in breathing (the diaphragm) after a brachial plexus nerve block (nerve "freezing").
- Trial name
- NCT01048021
- Testing
- Supraclavicular Block
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Proximal Tibia Fracture
The Efficacy and Cost Effectiveness of Preoperative and Postoperative Cryotherapy in Proximal Tibia Fractures
Consenting patients with proximal tibia fractures will be randomized to 10 degree or 21 degree cryotherapy sleeves. Time to discharge and complications will be monitored.
- Trial name
- ARCTIC CAT (NCT01104831)
- Testing
- Cryotherapy, Room temperature cuff
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Borderline Personality Disorder
Evaluation of a Modified Dialectical Behavior Therapy Program
The goal of this pilot project is to offer outpatient Dialectical Behavior Therapy (DBT) treatment as described in Linehan's text (1993), which is considered an effective treatment of borderline personality disorder.
- Trial name
- NCT01635556
- Testing
- Dialectical Behavior therapy
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- University of Manitoba
Determination of Clinical Effects, Presence of Inflammatory Cytokines
Long Term Comparison of Ultrasonic and Hand Instrumentation in the Maintenance of Peri-implant Tissues: A Randomized Clinical Trial
Nowadays, dental implants are a very attractive and affordable treatment option for patients. According to the American Society of Implant Dentistry the dental implant market in the U.S is projected to reach $1.3 billion by…
- Conditions
- Determination of Clinical Effects, Presence of Inflammatory Cytokines, Patients Perception of Discomfort, Titanium Scalers
- Trial name
- NCT02100384
- Testing
- Peri-implant maintenance
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
NAFLD, TYPE 2 DIABETES
Resveratrol for the Treatment of Non Alcoholic Fatty Liver Disease and Insulin Resistance in Overweight Adolescents
The current project is designed as a 30-day pilot trial to demonstrate the safety and tolerability of resveratrol therapy in overweight adolescents to decrease liver fat, and improve insulin sensitivity to prevent type 2 diabetes.
- Conditions
- NAFLD, TYPE 2 DIABETES, METABOLIC SYNDROME
- Trial name
- NCT02216552
- Testing
- Resveratrol
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of Manitoba
Peripheral Arterial Disease
Egg Study With Peripheral Arterial Disease
The current research study has the potential to generate data that would provide solid clinical endpoints as to the impact of including eggs in a regular diet in individuals with peripheral arterial disease.
- Trial name
- NCT01256320
- Testing
- Classic Egg Group, Omega 3 Egg Group
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Manitoba
Spinal Cord Injury, Tetraplegia
Omega-3 Supplementation for Tetraplegics With Poor Cholesterol Levels
People with a spinal cord injury (SCI) characteristically have low levels of high-density lipoprotein-cholesterol (HDL-c; "good cholesterol") and high levels of low-density lipoprotein-cholesterol (LDL-c; "bad cholesterol"), and…
- Conditions
- Spinal Cord Injury, Tetraplegia, Quadraplegia, Low HDL-c
- Trial name
- NCT01896037
- Testing
- Omega-3 supplements
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- University of Manitoba
Pre-Diabetes
Designer Functional Foods on Parameters of Metabolic and Vascular in Prediabetes
This is a multi-site, double-blind, randomized, controlled food intervention study being conducted at the Canadian Centre for Agri-Food Research in Health and Medicine (CCARM) in Winnipeg and the Mayo Clinic, Rochester, MN, to…
- Trial name
- PREFFER-2014 (NCT02400450)
- Testing
- Functional Ingredient Group, Control Ingredient Group
- Where
- 2 sites in United States, Canada
- Sponsor
- University of Manitoba
Vitamin D Deficiency
Effects of Vitamin D Fortification on Vitamin D Metabolite Profiles and Status in Vitamin D Insufficient Individuals
This is a cross-sectional study designed to compare plasma/serum and urine vitamin D metabolite profiles of vitamin D sufficient and insufficient individuals. There are two phases of this study.
- Trial name
- VITD-2013 (NCT02422784)
- Testing
- Rooibos Iced-Tea (Control), Rooibos Tea - Vitamin D3, Rooibos Tea- Vitamin D3 & Calcium
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Manitoba
Anterior Cruciate Ligament Injury
The Effects of Neuromuscular Exercise Training on Core Stability and Hip Strength in Healthy Adolescent Females
This study is an evaluation of the effects of a Neuromuscular training program on hip strength and core stability. It is a randomized clinical trial evaluating pre and post scores.
- Trial name
- NME hip/core (NCT03012711)
- Testing
- Neuromuscular exercise training
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Complications; Cesarean Section, Effects of; Anesthesia, Spinal and Epidural, in Pregnancy
Hemodynamic Effects of Low Dose Spinal Anesthesia for Cesarean Section
We propose to study the effects on hemodynamics (blood pressure, cardiac output, and central venous pressure) of two doses of bupivacaine for spinal anesthesia during cesarean section: a higher dose of 12 mg to a lower dose of…
- Conditions
- Complications; Cesarean Section, Effects of; Anesthesia, Spinal and Epidural, in Pregnancy, Hemodynamic Instability, Personal Satisfaction
- Trial name
- NCT02036697
- Testing
- Bupivacaine 4.5, Bupivacaine 9, Morphine
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Manitoba
Cardiovascular Diseases
For Her Heart's Sake STEP Project: A Clinical Trial
The goal of the proposed project is to determine if providing an intervention for women who decline the invitation to participate in standard cardiac rehabilitation programs (CRPs) will ultimately result in an increase their…
- Trial name
- FHHS: STEP (NCT02411188)
- Testing
- The STEP Program
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Manitoba
Smoking, Smoking Cessation
Prepare to Quit - A Clinical Trial to Help People Quit Smoking in a Community Dental Clinic Setting
The objectives of this study are: 1. To determine the effect that an intensive, community dental clinic centered, stop-smoking program using a motivational interviewing approach has upon cessation rates for interested, smoking…
- Trial name
- NCT01846910
- Testing
- Tooth Whitening, Motivational Counseling
- Where
- Canada
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- University of Manitoba