Clinical trials: sponsored by University of Manitoba
Healthy
Gender Effects of Dietary Omega-3 Fatty Acids From Plant and Marine Sources on Oxylipins in Healthy Humans
This study is single site, double-blind, randomized, cross-over study designed to compare the effects of flax oil and fish oil supplementation on the oxylipin profile in healthy males and females.
- Trial name
- OXGEN-2014 (NCT02317588)
- Testing
- Flax Oil, Fish Oil
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Hypercholesterolemia, CVD
Effect of Plant Sterol Enriched Milk on Plasma Lipid Levels of Humans Breast-fed During Infancy
The overall goal of this clinical study is to investigate how dietary cholesterol intake influences the plasma Total cholesterol (TC), LDL-Cholesterol levels and cholesterol metabolism between adults who had been breast-fed as…
- Trial name
- NCT01825668
- Testing
- Plant Sterols, High cholesterol
- Where
- Canada
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Type 2 Diabetes
Study of Liraglutide in Individuals With Type 2 Diabetes Using Insulin
Liraglutide is a GLP1 agonist used in the treatment of Type 2 diabetes and is is asociated with improved blood glucose control, weight loss and low rates of hypoglycemia when used alone or in combination with metformin.
- Trial name
- SAIL (NCT01628445)
- Testing
- liraglutide
- Where
- Canada
- Volunteers
- 52 people
- Sponsor
- University of Manitoba
Stress Urinary Incontinence
Trial Comparing TVT SECUR System and Trans Vaginal Obturator Tape for Surgical Management of Stress Urinary Incontinence
To compare the efficacy and complications of the TVT SECUR system (TVT S) and trans-vaginal obturator tape (TVT-O) procedures for the surgical management of female stress urinary incontinence.
- Trial name
- NCT00527696
- Testing
- transvaginal obturator tape
- Where
- Canada
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Stress Urinary Incontinence, Urethral Sling Surgery
Trial Comparing Mini-Arc Precise Pro and the Trans Vaginal Obturator Tape for Stress Urinary Incontinence
Randomized comparison of two surgeries for the treatment of female stress urinary incontinence.
- Trial name
- NCT01799122
- Testing
- Mini Arc Precise Pro and Trans vaginal obturator sling (TVT-0)
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Manitoba
Aging
The Effect of a Novel Dual-Task Exercise Program for Balance, Mobility and Cognition in Community Dwelling Older Adults
Goal: The development of a Treadmill Rehabilitation Platform (TRP) for task-orientated rehabilitation that provides an adapted, blended approach among older adults with balance, mobility, and cognitive impairments.
- Trial name
- NCT01940055
- Testing
- Dual task treadmill walking exercise program, Dual task recumbent cycling exercise program
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Peripheral Vestibular Disorders, Dizziness
Game Based Vestibular Exercise for Home Rehabilitation
Study Description and Purpose: The vestibular sense organs of the inner ear consist of the semi-circular canals and otolith end organs.
- Trial name
- NCT02134444
- Testing
- Experimental group, Control group
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Manitoba
Sequelae of Stroke
Effects of a Community-based Group Rehabilitation Program for Dynamic Balance and Mobility Post Stroke
Stroke patients clearly benefit from intensive and coordinated inpatient care. While inpatient rehabilitation care is the preferred form for many patients post-stroke, due to access and financial barriers, many patients do not…
- Trial name
- NCT01818271
- Testing
- conventional physical therapy, community-based group rehabilitation
- Where
- 2 sites in Canada
- Volunteers
- 24 people
- Sponsor
- University of Manitoba
Hypotension
Pilot Study: Paravertebral Analgesia vs Epidural Analgesia After Thoracotomy
Paravertebral analgesia is non-inferior to epidural analgesia for pain control and superior to epidural analgesia in terms of the main complication of hypotension.
- Trial name
- ParaEpi (NCT01700491)
- Testing
- Epidural Catheter 0.2% ropivacaine, Paravertebral Catheter 0.4% ropivacaine
- Where
- 2 sites in Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Muscle Development
Whole Milk Versus Whey Protein Supplement and Resistance Exercise
The purpose of the study is to examine the effects of consuming protein supplement (whey) compared to whole milk immediately after bouts of resistance training on muscular strength and body composition.
- Trial name
- NCT01580189
- Testing
- Whey protein, Chocolate milk, Sugar
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Catheter Related Infection, Bacteremia
Efficacy and Safety of an Ethanol/Sodium Citrate Locking Solution: A Pilot Study
Currently in Canada, either 4% sodium citrate or heparin 1,000-10,000 U/ml solutions are "locked" into hemodialysis catheters between dialysis sessions to prevent thrombosis.
- Trial name
- NCT01394458
- Testing
- 30 % ethanol / 4% sodium citrate catheter locking solution, Heparin 1000 u / ml
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Manitoba
Rewarming by Shivering Heat Production Only, Rewarming by Arm and Leg Immersion in Warm Water
Hypothermia Rewarming With Distal Limb Warming
The study will compare the rewarming effectiveness of heat donation through the distal arms and legs during rewarming of mildly hypothermic subjects.
- Conditions
- Rewarming by Shivering Heat Production Only, Rewarming by Arm and Leg Immersion in Warm Water, Rewarming by Arm and Leg Exposure to Fluidotherapy
- Trial name
- NCT01827449
- Testing
- Fluidotherapy warming device
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Post-laparoscopy Umbilical Port-site Wound Infection
The AVATAR Trial: Applying VAcuum To Accomplish Reduced Wound Infections
Postoperative pain and time taken to return to normal activities after laparoscopic surgery are significantly shorter. Wound infections still occur and contribute to prolonged hospital stays and morbidity.
- Trial name
- AVATAR (NCT01623427)
- Testing
- Application of vacuum, No vacuum
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- University of Manitoba
Novel H1N1 Influenzal Acute Respiratory Infection
Severe Pandemic H1N1 Infection in ICU: Comparative Resource Utilization
The main purpose of this study is to review the resource utilization of severe adult H1N1 pneumonia undergoing antiviral and oxygen therapy, mechanical ventilation and support with pulmonary rescue therapies ( nitric oxide, ECMO…
- Trial name
- NCT01485237
- Testing
- We will compare the resources used by both groups
- Where
- Canada
- Volunteers
- 400 people
- Sponsor
- University of Manitoba
Fibromyalgia Syndrome
Online Acceptance-based Behavioural Treatment for Fibromyalgia
A recent study published by the Canadian Pain Society estimated the direct health care costs of chronic pain to be about 6 billion dollars.
- Trial name
- NCT01642810
- Testing
- Acceptance-based behavioural therapy, Will vary per participant
- Where
- Canada
- Volunteers
- 67 people
- Sponsor
- University of Manitoba
Infant Development
A Community Based Implementation of a Toolkit and Parenting Program for Improving Brain Development in Newborns
The investigators propose to develop and test the efficacy of a low cost evidence based toolkit aimed at improving brain development among newborns a rural setting of Pakistan.
- Trial name
- NCT02290756
- Testing
- Parenting Program, Low cost evidence based toolkit
- Where
- Pakistan
- Volunteers
- 1,080 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Hypercholesterolemia
Effect of Beta-Glucan on Cholesterol Lowering
The primary aim of this study is to determine whether the cholesterol-lowering efficacy of barley b- glucan varied as function of molecular weight (MW) and the total daily amount consumed.
- Trial name
- NCT01408719
- Testing
- Control, 3g LMW beta-glucan, 5g LMW beta-glucan
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Critical Lower Limb Ischemia, Critical Limb Ischemia
Evaluation of Carbothera in the Treatment of Foot Ulcers
Foot ulceration usually precedes more serious foot complications such as infection, gangrene or amputation. The risk of developing foot ulcers has been estimated to be higher in individuals with kidney disease.
- Conditions
- Critical Lower Limb Ischemia, Critical Limb Ischemia, Foot Ulcer, Skin Ulceration
- Trial name
- NCT02239419
- Testing
- CO2-Enriched Tap Water (Carbothera), Non-CO2-Enriched Tap Water
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- University of Manitoba
Parkinson's Disease, Cognitive Impairment
Study of the Effect of the Cognitive Orientation to Daily Occupational Performance (CO-OP) on Cognitive Impairment in Parkinson's Disease
The purpose of the study will be to determine the effects of the Cognitive Orientation to daily Occupational Performance (CO-OP) as a treatment program for individuals with Parkinson's disease-related cognitive impairment.
- Trial name
- NCT02007785
- Testing
- CO-OP treatment protocol
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- University of Manitoba
Neuropathic Pain, Allodynia
Botulinum Toxin Type A for Treating Allodynic Pain in SCI and MS
This study will examine the efficacy of Botulinum Toxin Type A ("Botox") in treating Allodynic-type neuropathic pain in people with spinal cord injury or multiple sclerosis.
- Trial name
- NCT01911377
- Testing
- Botulinum Toxin Type A, Normal Saline for Injection
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University of Manitoba