Clinical trials: sponsored by University of Manitoba
Septic Shock, Delirium
Septic Shock and Delirium Because of rSO2 Abnormalities in Intensive Care Unit Patients (The SAD BRAIN Study)
Delirium in the ICU is a prevalent problem occurring in up to 80% of ICU patients. A potential cause of delirium in ICU patients could be cerebral hypoxia. Septic shock is associated with high rates of delirium.
- Conditions
- Septic Shock, Delirium, Renal Failure
- Trial name
- NCT01836302
- Testing
- Observation
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- University of Manitoba
Obesity, Pregnancy
Inflammation in Obese Parturients: Surgical Outcomes After Elective Caesarean Section
Hypothesis: The investigators propose that obese parturients will have an increased inflammatory response and a decreased anti-inflammatory response to the surgical and anesthetic insult of caesarean section and that this will be…
- Conditions
- Obesity, Pregnancy, Cesarean Section
- Trial name
- NCT01836315
- Testing
- Observational Study
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- University of Manitoba
Abdominal Aortic Aneurysm Uncomplicated
Goal Directed Therapy for Patients Undergoing Major Vascular Surgery
The management and delivery of intravenous fluids during surgical operations is one of the important duties for anesthesiologists.
- Trial name
- NCT01681251
- Testing
- Fluid titrated with the use of arterial pulse contour cardiac output monitor if SVV >13%, Fluid titrated at the discretion of the attending anesthesiologist
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Manitoba
Healthy Children, Elementary School Age
Healthy Buddies Manitoba
School-based interventions are generally ineffective for preventing weight gain in children. In 2007, a group from the University of British Columbia, developed a program called Healthy Buddies, that relied on peer mentors to…
- Conditions
- Healthy Children, Elementary School Age, Rural and Urban, First Nations
- Trial name
- NCT01979978
- Testing
- Healthy Buddies Curriculum
- Where
- Canada
- Volunteers
- 647 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Bradycardia, Hypoxemia
Atropine Versus no Atropine for Neonatal Rapid Sequence Intubation
The purpose of this study is to compare heart rate in infants who receive atropine as a part of their medication before intubation to those who do not.
- Trial name
- NCT01595399
- Testing
- atropine
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- University of Manitoba
Peripheral Vestibular Disorders, Vestibular Syndromes &/or Disorders (Labyrinthine)
Home-based Computer Gaming in Vestibular Rehabilitation
It is hypothesized that a home-based computer gaming rehabilitation program will improve gaze control and balance impairments in those with peripheral vestibular disorders (PVD).
- Conditions
- Peripheral Vestibular Disorders, Vestibular Syndromes &/or Disorders (Labyrinthine), Vestibular Neuronitis
- Trial name
- NCT01943955
- Testing
- home-based computer gaming
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of Manitoba
Tumors
18F-Fluorodeoxyglucose Positron Emission Tomography in Oncology and Neurology
This clinical trial is being conducted to study the use of a radioactive glucose tracer as an imaging test [Positron Emission Tomography (PET)scan] in adults who have or are suspected of having cancer and in another group of…
- Trial name
- NCT01180751
- Testing
- [18F]-Fluorodeoxyglucose
- Where
- Canada
- Volunteers
- 1,000 people
- Sponsor
- University of Manitoba
Dysphagia
Effects of Free Water Protocol on Inpatients in a Neurological Rehabilitation Setting
Inpatients in the neurology rehabilitation units at Riverview Health Center- people who are brain-injured and or who have had a stroke - often have dysphagia as a result of their condition.
- Trial name
- NCT01209910
- Testing
- Water
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Manitoba
Insomnia, Insomnia Disorder
Internet-based Treatment for Chronic Insomnia
Study Objectives. Despite effective cognitive behavioral treatments for chronic insomnia, such treatments are underutilized. This study evaluates the impact of a 6-week, online treatment for insomnia.
- Trial name
- NCT00821041
- Testing
- Cognitive Behavioral Therapy
- Where
- Canada
- Volunteers
- 118 people
- Sponsor
- University of Manitoba
Healthy Metabolism
Urinary Excretion of Acetylamantadine by Normal Healthy Volunteers
Amantadine appears to be a specific substrate for acetylation by spermidine/spermine N1-acetyltransferase (SSAT). SSAT activity in cancer cells is higher by several-fold compared to normal cells.
- Trial name
- NCT01467258
- Testing
- Amantadine
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Fracture, Pain
Ibuprofen Versus Codeine. Is One Better for Post-operative Pain Relief Following Reduction of Paediatric Forearm Fractures?
For simple fractures treated in the emergency department with cast immobilisation only, ibuprofen has been shown to be superior to, or a least or equivalent to codeine with less side effects.
- Trial name
- NCT01605240
- Testing
- Acetaminophen and Ibuprofen, Acetaminophen and Codeine
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Manitoba
Septic Shock
Cytokine Response in Septic Shock
This study is designed to examine the early sequential cytokine responses during antibiotic therapy and resuscitation of septic shock in relation to clinical manifestations of disease.
- Trial name
- NCT01770457
- Where
- Canada
- Volunteers
- 325 people
- Sponsor
- University of Manitoba
Septic Shock
A Retrospective Review of a Comprehensive Cohort of Septic Shock: Assessment of Critical Determinants of Outcome
Septic shock remains the dominant cause of death in ICU's of the developed world with approximately 400,000 cases annually in the US and another 20,000 annually in Canada.
- Trial name
- NCT01775956
- Where
- Canada
- Volunteers
- 10,000 people
- Sponsor
- University of Manitoba
Aortic Stenosis
The Effects of High Spinal Anesthesia on Heart Function, Stress Response and Pain Control in Aortic Valve Surgery
This study is looking at the effects of high spinal anesthesia (also known as total spinal anesthesia) combined with general anesthesia versus general anesthesia alone on the following: Stress response: Patients undergoing aortic…
- Trial name
- NCT00348920
- Testing
- High Spinal and General Anesthesia
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- University of Manitoba
Respiratory Distress Syndrome
Early CPAP And Large Volume Minimally Invasive Surfactant (ECALMIST) in Preterm Infants With RDS
Modification of Minimally Invasive Surfactant Therapy (MIST) to a new technique called ECALMIST (Early CPAP And Large volume Minimal Invasive Surfactant).
- Trial name
- ECALMIST (NCT01553292)
- Testing
- ECALMIST
- Where
- 3 sites in Canada
- Volunteers
- 21 people
- Sponsor
- University of Manitoba
Periodontal Disease
Power Toothbrush Use in Nursing Homes to Eliminate Mouth and Body Inflammation
The purpose of this study is to investigate whether brushing the teeth of nursing home residents with a power toothbrush as compared with standard care typically provided in nursing homes, will increase caregiver compliance with…
- Trial name
- NCT01639183
- Testing
- Rotating-oscillating Power Toothbrush, Standard Care
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Intentional Injury
A WrapAround Case Management Program for Youth Injured by Violence
This is a feasibility study of a WrapAround Case Management Program for Youth Injured by Violence. Youth (aged 10-24) who have been injured by violence and visit the emergency department will be offered a support worker who will…
- Trial name
- NCT01751464
- Testing
- WrapAround Case Management
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- University of Manitoba
Lung Cancer
To Evaluate the Impact of PET/CT on Radiation Treatment Planning in Relation to Changes in GTV in Stage 3 NSCLC
Acknowledging that level I evidence already exists regarding the general beneficial impact on FDG PET in the staging and subsequent management of lung cancer the investigators postulate that fusing PET/CT data sets with RT CT…
- Trial name
- NCT01888692
- Where
- Canada
- Volunteers
- 29 people
- Sponsor
- University of Manitoba
Colorectal Cancer
Innovative Tools to Improve Colorectal Cancer Screening Rates in Manitoba
The primary purpose of the study is to investigate the efficacy and effectiveness of a community-based nurse managed telephone support line (Provincial Health Contact Center; PHCC) and Colorectal Cancer Information and Screening…
- Trial name
- NCT01026753
- Testing
- Refrigerator Magnet
- Where
- Canada
- Volunteers
- 2,395 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Rewarming by Shivering Heat Production Only, Rewarming by External Heat to the Torso
Effectiveness of Heat Donation Through the Head or Torso on Mild Hypothermic Rewarming
The study will compare the rewarming effectiveness of heat donation through the head or the torso during rewarming of mildly hypothermic subjects.
- Conditions
- Rewarming by Shivering Heat Production Only, Rewarming by External Heat to the Torso, Rewarming by External Heat to the Head
- Trial name
- NCT01603511
- Testing
- Rewarming modality
- Where
- Canada
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Manitoba