Clinical trials: sponsored by University of Manitoba
Kidney Transplantation
Pilot Study on the Use of Sirolimus to Treat Chronic Allograft Nephropathy in Children After Kidney Transplant
The purpose of this study is to determine whether treatment with sirolimus, in combination with low-dose tacrolimus and prednisone, is effective for the treatment of chronic allograft nephropathy (progressive scarring) in…
- Trial name
- NCT00188955
- Testing
- sirolimus
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Manitoba
Body Weight, Body Composition
Use of Conjugated Linoleic Acid as a Nutraceutical for Weight Loss in Humans
The purpose of the study is to examine how a naturally occurring fat found in meats, such as beef and lamb and milk, called conjugated linoleic acid (CLA), will affect your body weight and body fat content, blood fat levels, as…
- Conditions
- Body Weight, Body Composition, Hyperlipidemia, Inflammation
- Trial name
- CLA (NCT01047280)
- Testing
- Clarinol G-80 ® treatment, Safflower oil, G-c9, t11
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Internal Carotid Artery Stenosis
EEG, Cerebral Oximetry, and Arterial to Jugular Venous Lactate to Assess Cerebral Ischemia During Carotid Endarterectomy
A highly desired result during carotid endarterectomy (CEA) is the ability to predict and warn the surgeon if the brain is at risk of damage during the period of time that the carotid artery is cross-clamped for surgical repair…
- Trial name
- NCT00737334
- Testing
- EEGo, BIS, FORE-SIGHT cerebral oximeter
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Manitoba
Coronary Heart Disease
Efficacy of Sterol Enhanced Soy Beverage on Cholesterol Metabolism, Inflammation and Oxidative Status in Humans
It is becoming increasingly clear that North Americans prefer dietary approaches to enhance health in favour of pharmaceutical approaches.
- Trial name
- NCT00924391
- Testing
- phytosterol enhanced soy based beverage, 1% milk
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Hypercholesterolemia
Efficacy of Sterol-Fortified Low Fat Soy Beverage on Cholesterol Metabolism, Inflammation and Oxidative Status in Humans - Study II
Hypercholesterolemia is a well-established risk factor for the development of atherosclerosis, a component of cardiovascular disease (CVD).
- Trial name
- NCT00923403
- Testing
- plant sterol enriched soymilk, control dairy milk
- Where
- Canada
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Diabetes
Glycemic Responses and Sensory Characteristics of Whole Yellow Pea Flour Added to Novel Functional Foods
The objective of this study was to determine if whole yellow pea flour reduces post-prandial glycemic responses of novel food products.
- Trial name
- NCT00877968
- Testing
- Whole wheat banana bread, Whole pea flour banana bread, Whole wheat biscotti
- Where
- Canada
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Uterine Fibroids, Menorrhagia
Uterine Artery Embolization for Symptomatic Fibroids
This study will evaluate the safety, efficacy , quality of life and patient satisfaction of uterine artery embolization for the treatment of symptomatic uterine fibroids.
- Conditions
- Uterine Fibroids, Menorrhagia, Adenomyosis
- Trial name
- NCT00354471
- Testing
- Uterine Artery Embolization
- Where
- Canada
- Sponsor
- University of Manitoba
Thrombosis
Alteplase for Blood Flow Restoration in Hemodialysis Catheters
We are investigating a new way of administering alteplase to remove clots from hemodialysis catheters. Currently, alteplase is left to dwell inside the catheter between dialysis treatments to dissolve the clot and restore blood…
- Trial name
- NCT00303420
- Testing
- Alteplase "push" protocol, alteplase dwell arm
- Where
- 9 sites in Canada
- Volunteers
- 180 people
- Sponsor
- University of Manitoba
Kidney Failure, Chronic
Trial of Aerobic Exercise in Patients Undergoing Outpatient Hemodialysis
Randomized controlled trial comparing effects of ergometer exercise during hemodialysis to effects of pedometer use outside of hemodialysis on exercise capacity, functional status, quality of life and adequacy of hemodialysis.
- Trial name
- NCT00492362
- Testing
- ergometer exercise during hemodialysis, pedometer activity outside of hemodialysis
- Where
- 4 sites in Canada
- Volunteers
- 60 people
- Sponsor
- University of Manitoba
Cerebral Aneurysm, Trigeminal Neuralgia
EEG Monitoring to Assess Emergence From Neuroanesthesia
A highly desired result in neuroanesthesia is a prompt, controlled emergence following a neurosurgical procedure. Considerable strides have been made in this direction with volatile anesthetic agents such as sevoflurane or…
- Trial name
- NCT00443807
- Testing
- On-line EEG monitoring during neurosurgery, EEGo vs BIS
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- University of Manitoba
Spasticity in Spinal Cord Injured Persons
Randomized Double Blind Cross Over Study for Nabilone in Spasticity in Spinal Cord Injury Persons
Objectives: To determine whether nabilone, a synthetic cannabinoid, alleviates spasticity in people with spinal cord injury (SCI). Methods: Twelve subjects were enrolled in this double-blind, placebo-controlled, crossover study.
- Trial name
- NCT00623376
- Where
- Canada
- Sponsor
- University of Manitoba
Intubation, Endotracheal
Use of the Stethoscope to Confirm Breathing Tube Placement
This study is intended to validate the use of neck auscultation with an electronic stethoscope during intubation to confirm tracheal tube placement.
- Trial name
- NCT00378651
- Testing
- Neck Auscultation
- Where
- Canada
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Apnea, Infant, Premature
Randomized Trial of Nasal Continuous Positive Airway Pressure or Synchronized Nasal Ventilation in Premature Infants.
Very premature infants uniformly do not have mature functioning lungs to breathe well nor mature regulation mechanisms to breathe regularly. Assistance with a mechanical respirator is common.
- Conditions
- Apnea, Infant, Premature, Bronchopulmonary Dysplasia
- Trial name
- NCT00188968
- Testing
- Nasal Continuous Positive Airway Pressure, Synchronized Nasal Positive Pressure Ventilation
- Where
- 2 sites in Canada
- Volunteers
- 48 people
- Sponsor
- University of Manitoba
Acute Uncomplicated Pyelonephritis
Safety and Efficacy Study of the Treatment of Kidney Infections With Short Course Levofloxacin
The purpose of the study is to compare the safety and effectiveness of the antibiotic levofloxacin by administering a higher dose of levofloxacin using a shorter course of therapy to treat patients with infections of their kidney.
- Trial name
- NCT00239161
- Testing
- Levofloxacin
- Where
- 4 sites in Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Manitoba