Clinical trials: sponsored by University of Miami
Cannabis Use, Depression
Neural and Psychiatric Consequences of Cannabis Use in Adolescents
The goal of this study is to investigate the effects of cannabis on brain function among adolescents with depression.
- Trial name
- Cann-Teen (NCT06941298)
- Testing
- Neuroimaging Investigation
- Where
- 2 sites in United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- University of Miami
Glioma, Brain Tumor
Non-invasive Glioma Characterization Through Molecular Imaging
MRI-based sequences can provide non-invasive quantification of intratumoral 2-hydroxyglutarate (2HG) distribution and tumor cellularity in human gliomas and help guide the development of novel glioma therapies.
- Conditions
- Glioma, Brain Tumor, Primary Brain Tumor, Malignant Glioma
- Trial name
- NCT03684109
- Testing
- 3T MRI Scanner
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Miami
Benign Prostatic Hyperplasia
Investigation of Prostate Artery Embolization Compared to Holmium Laser Enucleation of Prostate
The purpose of this research study is to evaluate prostate artery embolization (PAE) compared to Holmium laser enucleation of prostate (HoLEP) in improving a patient's overall prostate related symptoms.
- Trial name
- NCT05155891
- Testing
- Embosphere Microspheres, HoLEP Procedure
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Miami
Hiv
Finishing HIV Project
This study aims to learn how to help enable healthy behaviors and lower the risk of HIV among Latinx Men.
- Trial name
- NCT06406049
- Testing
- Control group-Standard Health Promotion, Social network intervention
- Where
- United States
- Volunteers
- 624 people, healthy volunteers welcome
- Sponsor
- University of Miami
Lymphedema
Lymphedema Specific PROs for Risk Assessment, Prevention and Early Detection
The purpose of this study is to find a way to detect a surgical complication, called lymphedema, at an earlier stage. This potential complication may develop in some patients after removal of the armpit lymph nodes (axillary…
- Trial name
- NCT05929001
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- University of Miami
Virtual Reality, Fear
Empathy and Virtual Reality (VR)
This study will characterize the subjective and physiological changes associated with empathy following a fear-inducing virtual reality (VR) experience.
- Trial name
- NCT07314788
- Testing
- Fear-inducing Virtual Reality (VR) experience, Neutral Virtual Reality (VR) experience
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Miami
Total Knee Arthroplasty, Prosthetic-joint Infection
Methylene Blue in Total Knee Arthroplasty (TKA)
The purpose of this pilot study is to determine the volume of irrigation required to achieve macroscopic clearance of contaminants during a debridement, antibiotics, and implant retention (DAIR) procedure for periprosthetic joint…
- Conditions
- Total Knee Arthroplasty, Prosthetic-joint Infection, Irrigation
- Trial name
- NCT07324954
- Testing
- Methylene Blue 10 MG/ML (intra-articular application), Revision Arthroplasty for PJI (DAIR), Primary Total Knee Arthroplasty
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Miami
Acute Ischemic Stroke, Mesenchymal Stem Cells
Expanded Access Multi-Patient Experimental Treatment Involving Allogeneic Human Mesenchymal Stem Cells (hMSCs) in Subjects With Acute Ischemic Stroke (EXPAND)
The purpose of this study is to use an intravenous infusion of allogeneic human mesenchymal stem cells (Allo-hMSCs) to treat an acute ischemic stroke condition.
- Conditions
- Acute Ischemic Stroke, Mesenchymal Stem Cells, Stroke, Acute, Stroke/Brain Attack
- Trial name
- EXPAND (NCT05522569)
- Testing
- Allogeneic human mesenchymal stem cells (Allo-hMSCs)
- Where
- United States
- Sponsor
- University of Miami
Graft Vs Host Disease, Coping Skills
Horizons Chronic Graft-Versus-Host-Disease Study
This research is being done to evaluate the feasibility of the Horizons Program, a group-based behavioral intervention, to enhance quality of life in patients with chronic graft-versus-host disease.
- Conditions
- Graft Vs Host Disease, Coping Skills, Quality of Life, Stem Cell Transplant Complications
- Trial name
- NCT06160986
- Testing
- Horizons Group Intervention
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Miami
Multiple Myeloma, Smoldering Multiple Myeloma
Two Biologically and Clinically Distinct Entities: Progressive Versus Stable Multiple Myeloma (MM) Precursor Conditions
The key aim of the study is to define the two biologically and clinically distinct entities: progressive versus stable myeloma precursor conditions.
- Conditions
- Multiple Myeloma, Smoldering Multiple Myeloma, Monoclonal Gammopathy of Undetermined Significance
- Trial name
- TRANSFORMM (NCT05361694)
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- University of Miami
Fuchs' Endothelial Dystrophy, Corneal Edema
Plasma Rich in Growth Factors in Corneal Endothelial Transplantation
The purpose of the study is to determine the safety and efficacy of brief intraoperative corneal endothelial graft incubation in plasma rich in growth factors (PRGF) for reducing postoperative endothelial cell loss.
- Trial name
- NCT06261346
- Testing
- Endothelial keratoplasty, PRGF
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of Miami
Ulcerative Colitis
Tailored Anti-Inflammatory (A-I) Diet for Americans With Ulcerative Colitis (UC)
The purpose of this study is to test the effect of an anti-inflammatory diet that incorporates native foods of the American diet on disease remission in American patients with Ulcerative Colitis (UC) and to identify biomarkers of…
- Trial name
- NCT06784323
- Testing
- Catered diet, Diet guidance sessions, Dietary counseling
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- University of Miami
Immune Defect
Opioid, HIV and Immune System
The purpose of this research is to evaluate blood samples from HIV infected and non-HIV infected people opioid and non opioid users to understand how opioid affect the immune responses (body defenses against infection) to the flu…
- Trial name
- NCT04304768
- Testing
- Fluzone Quadrivalent
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Miami
Skin Toxicity
Application of Chinese Herbal Complementary and Alternative Medicine (CAM) to Improve Human Health and to Further Botanical and Horticultural Sciences
The purpose of this research is to study a Chinese herbal Complementary and Alternative Medicine (CAM) product for the temporary relief of pain and itching after radiotherapy (RT).
- Trial name
- NCT04650256
- Testing
- Complementary and alternative medicine (CAM)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Miami
Chronic Graft-Versus-Host Disease, Quality of Life
Digital Health Intervention to Promote Quality of Life in Adults With Chronic Graft Versus Host Disease
The goal of this interventional study is to learn if the Horizons mobile application is feasible for survivors of allogeneic hematopoietic stem cell transplant who have chronic graft-versus-host disease.
- Trial name
- NCT06688942
- Testing
- Horizons App Intervention
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Miami
Breast Cancer
Prospective Evaluation of Targeted Axillary Dissection (TAD)
The purpose of this research is to evaluate how to manage the axillary lymph nodes in patients with breast cancer. The investigators will determine if a sampling of the lymph nodes under the arm will give the information…
- Trial name
- TAD (NCT04998682)
- Testing
- Axillary Dissection
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Miami
Multiple Myeloma
A Study of Daratumumab, Carfilzomib, Lenalidomide, and Dexamethasone in Patients With Newly-Diagnosed Multiple Myeloma
This study is being done to find out whether carfilzomib, lenalidomide, and dexamethasone (KRD) or KRD and Daratumumab (KRD+DARA) might be safer and more effective ways of controlling multiple myeloma than the standard of care…
- Trial name
- ADVANCE (NCT04268498)
- Testing
- Bortezomib, Dexamethasone, Lenalidomide
- Where
- 7 sites in United States
- Volunteers
- 310 people
- Sponsor
- University of Miami
Obstructive Sleep Apnea, Fat Disorder
Metabolism and Sleep Apnea Treatment
The purpose of this research study is to see if obstructive sleep apnea (OSA) is associated with abnormalities in fat metabolism.
- Trial name
- MaST (NCT05539716)
- Testing
- PAP Therapy, Lifestyle Counseling Intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Miami
Obesity, Activity, Motor
Efficacy Trial of Healthy Together ("Juntos")
The purpose of this study is to assess the efficacy of a family-based digital (web and mobile phone-based) program known as Healthy Together ("Juntos") in preventing increases in body mass index and improving moderate-to-vigorous…
- Conditions
- Obesity, Activity, Motor, Diet, Healthy
- Trial name
- NCT06489262
- Testing
- Healthy Together ("Juntos")
- Where
- United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- University of Miami
Lung Diseases
Prophylaxis Guided by Cytomegalovirus-specific T Cell Immunity to Prevent Cytomegalovirus Disease in Lung Transplant Recipients
The purpose of this study is to evaluate the clinical outcomes of Cytomegalovirus (CMV) virus in the participants' body. Therefore, the study team will follow the participants' immunological response based on the Cytomegalovirus…
- Trial name
- NCT06494033
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Miami