Clinical trials: sponsored by University of Miami
Glaucoma
Stop Retinal Ganglion Cell Dysfunction Study
Glaucoma is a progressive disease resulting in blindness. Determining the onset of the disease, predicting its severity and the benefit of pressure lowering eye drops is key to clinical management aimed at maintaining useful…
- Trial name
- STOP-RGCD (NCT02390284)
- Testing
- Latanoprost, Bimatoprost, Travoprost
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Miami
Venous Leg Ulcer
VLU Dressing Study
The goal of the study is to investigate the effectiveness of Cutimed Sorbact (Study Device) in modifying bacterial load in venous leg ulcers (VLU).
- Trial name
- NCT03621592
- Testing
- Cutimed® Sorbact®, Acticoat®
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Miami
Post Traumatic Stress Disorder
Expressing Personal Recollections in English or Spanish to Alleviate Traumatic Emotions (Exprésate)
The purpose of this study is to test if expressive writing about traumatic events has positive changes in women living with post-traumatic stress.
- Trial name
- Exprésate (NCT05090839)
- Testing
- Weekly Emotional Disclosure (WED), Weekly Emotional Disclosure (WED) Spanish
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Miami
Healthy
Transcutaneous Vagus Nerve Stimulation (taVNS) Dosage Study 1
The purpose of this research study is to investigate the effects of different forms of a gentle form of electrical stimulation applied to the ear, known as transcutaneous auricular vagus nerve stimulation (taVNS).
- Trial name
- NCT06381102
- Testing
- transcutaneous auricular vagus nerve stimulation 30/30, transcutaneous auricular vagus nerve stimulation 10/10
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Miami
Ptosis, Eyelid
Phenylephrine Versus Eyelid Taping for Muller's Muscle-Conjunctival Resection (MMCR) Evaluation
This research study aims to compare whether Phenylephrine 2.5% ophthalmic eye drop solution can serve as a better indicator of the effect of a drooping upper eyelid (ptosis) by covering part of the upper portion of the field of…
- Trial name
- NCT05890027
- Testing
- Phenylephrine Ophthalmic, Eyelid Tape
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Miami
Obsessive-Compulsive Disorder
Online Exposure Therapy for Obsessive-Compulsive Disorder (OCD) Study
The overarching goal of this protocol is to investigate mechanisms that influence symptom outcomes of exposure and response prevention (ERP) therapy for OCD.
- Trial name
- NCT06470893
- Testing
- OCD-NET
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of Miami
Other Disorders of Autonomic Nervous System
Interval Training and Parkinson's Disease
This research is designed to compare the impact of high-intensity interval training and high-velocity circuit resistance training on heart rate variability, gait, and functional performance in patients with Parkinsons disease.
- Trial name
- NCT06606743
- Testing
- High-Intensity Interval Training, High-Velocity Circuit Resistance Training
- Where
- 2 sites in United States
- Volunteers
- 39 people
- Sponsor
- University of Miami
Parkinson Disease
Top Set and Parkinson's Disease
This project will focus on improving power in adults with Parkinson's disease, since power is related to performance of daily activities and memory and decision making.
- Trial name
- NCT06801704
- Testing
- Top Set Resistance Training, Power Resistance Training
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Miami
Mental Health Wellness 1
Jump Start on the Go: Improving Resiliency and the Social-Emotional Development of At-Risk Preschool Children
The purpose of this study is to test the Jump Start on the Go (JS Go), an app-based program and see how helpful it is at improving resiliency and behavior support within childcare settings.
- Trial name
- NCT06374550
- Testing
- Jump Start on the Go, Jump Start Plus Coronavirus Support
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of Miami
Cancer, Hiv
SmartManage Stress Management for HIV+ Cancer Survivors
The purpose of this study is to design and refine a web-based platform developed for managing symptom burden in men who have sex who are HIV+ cancer survivors.
- Conditions
- Cancer, Hiv, Stress
- Trial name
- NCT04544917
- Testing
- SmartManage for HIV+ cancer survivors, Educational Control
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Miami
Mantle-Cell Lymphoma
Rituximab and Combination Chemotherapy in Treating Patients With Previously Untreated Mantle Cell Lymphoma
The investigator(s) hypothesize that Rituximab together with combination chemotherapy, followed by Rituximab maintenance therapy, will provide better disease control with improved response rates and overall survival in patients…
- Trial name
- NCT00878254
- Testing
- G-CSF, Rituximab, Cyclophosphamide
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Miami
Prostate Cancer
MRI Based Active Selection for Treatment Trial
The main purpose of this study is to determine if Magnetic Resonance Imaging (MRI), along with MRI targeted biopsy of suspicious lesions, is of value in detecting patients who would be likely to require treatment earlier.
- Trial name
- MAST (NCT02242773)
- Testing
- Multi-Parametric MRI, MRI-Guided Biopsy
- Where
- United States
- Volunteers
- 208 people
- Sponsor
- University of Miami
Parents, Mental Health Issue
The Development and Evaluation of a Single Session Intervention for Parent Distress Tolerance
The purpose of this study is to study different ways to help parents cope with strong emotions. The study team will be looking at how two different treatments help parents learn to manage strong emotions.
- Conditions
- Parents, Mental Health Issue, Distress, Emotional
- Trial name
- NCT05955898
- Testing
- Parents THRIVE, Sharing Feelings Project
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of Miami
Eye Infections, Bacterial
Comparison of Conjunctival Antimicrobial Activity and Patient Comfort Between Topical Hypochlorous Acid (Avenova) and Betadine
The purpose of this research study is to find out how Avenova (0.01 % hypochlorous acid) works compared to Betadine (Povidone iodide) for reducing bacteria and patient discomfort in the eyes.
- Trial name
- NCT04981860
- Testing
- Betadine, Avenova
- Where
- 2 sites in United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of Miami
Type2 Diabetes, Coronary Artery Disease
Liraglutide Effects on Epicardial Fat Inflammatory Genes
Epicardial adipose tissue (EAT) is the visceral fat of the heart. EAT could locally affect the coronary arteries through local secretion of pro-inflammatory cytokines.
- Trial name
- NCT03260881
- Testing
- Liraglutide Pen Injector [Victoza]
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Miami
Stress
VSMART (Video-Conference Stress Management and Relaxation Training for Older Women With Breast Cancer)
The proposed study tests the effects of a novel remotely-delivered group cognitive behavioral stress management (R-CBSM) intervention on improving health and quality of life in older women undergoing breast cancer (BCa)…
- Trial name
- VSMART (NCT03955991)
- Testing
- R-CBSM, Influenza vaccine
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- University of Miami
Risk Behavior
Evaluation of Values in Perspective (VIP) Program
The primary purpose of this study is to evaluate the effectiveness and perceived usefulness of the Values in Perspective (VIP) program in reducing and preventing engagement in risky behaviors among youths.
- Trial name
- NCT04879342
- Testing
- VIP Program
- Where
- United States
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- University of Miami
Psoriasis, Healthy
Brain Changes in Psoriasis After Secukinumab Treatment
The purpose of this study is to assess the effect of a biologic drug targeting the Interleukin (IL)-17 pathway (secukinumab) on brain plasticity and examine whether the plastic changes correlate with the improvement of perception…
- Trial name
- NCT04717466
- Testing
- Secukinumab
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Miami
Smoking, Smoking Cessation
Testing Integrative Smoking Cessation for HIV Patients
The purpose of this study is to examine the feasibility, acceptability and effect of a combined smoking cessation intervention integrating contingency management (reward-based) strategies with Mindfulness training to identify the…
- Conditions
- Smoking, Smoking Cessation, HIV Infections
- Trial name
- NCT05030766
- Testing
- Nicotine Replacement Therapy, Mindfulness Training Smoking Cessation Intervention, Contingency Management Smoking Cessation Intervention
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- University of Miami
Sleeve Gastrectomy
Crural Dissection in Sleeve Gastrectomy
The purpose of this study is to identify if there is a benefit in routine dissection of the diaphragmatic crura during sleeve gastrectomy.
- Trial name
- NCT04168060
- Testing
- Crura dissection, Sleeve gastrectomy, Hiatal hernia repair
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- University of Miami