Clinical trials: sponsored by University of Miami
Depression, Anxiety
Community Study of Outcome Monitoring for Emotional Disorders in Teens
This study is being done to compare three types of talk therapies for youth who struggle with emotional and behavioral problems (e.g., anxiety, sadness, worries) in Community Mental Health Clinics in Connecticut (CT) and Florida…
- Trial name
- COMET (NCT02567266)
- Testing
- Unified Protocol for Adolescents (UP-A), Youth Outcomes Questionnaire, Treatment as Usual
- Where
- 2 sites in United States
- Volunteers
- 196 people
- Sponsor
- University of Miami
Keratoconus
The Role of Antioxidant Supplementation in Keratoconus Patients
Keratoconus is the most common primary cornea ectasia, where the cornea undergoes structural changes, leading to loss of tissue integrity and vision loss. The prevalence of Keratoconus is 1:2000 in the general population.
- Trial name
- NCT02827747
- Testing
- Antioxidants (Vitamins A,C,E) plus GSH, Centrum, Dietary Sources
- Where
- United States
- Sponsor
- University of Miami
Asthma, Obesity
HealthSpark: Health Access for Children in Federally-Subsidized Child Care
HealthSpark is a community-based research network of childcare centers designed to improve the health of children in Miami-Dade County.
- Conditions
- Asthma, Obesity, ADHD
- Trial name
- NCT00339027
- Where
- United States
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- University of Miami
Behavior, Child
Teacher Child Interaction Training (TCIT): Randomized Control Trial
This study is being conducted to evaluate the effects of TCIT on child development, child behavior, and teacher use of skills in the classroom.
- Trial name
- NCT04000230
- Testing
- TCIT, Booster
- Where
- 4 sites in United States
- Volunteers
- 622 people, healthy volunteers welcome
- Sponsor
- University of Miami
Hemoglobin SC Disease, Anemia, Sickle Cell
Parent Educational Program for Children With Sickle Cell Disease
Children with sickle cell disease (SCD) are at risk for central nervous system (CNS) complications, which may affect academic achievement.
- Trial name
- NCT00860782
- Testing
- Parent Educational Support
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- University of Miami
Multiple Sclerosis
Histaminergic Basis of Fatigue in Multiple Sclerosis
The purpose of this research study is to identify a way to improve the feeling of exhaustion that patients might experience because of Multiple Sclerosis (MS).
- Trial name
- NCT04764383
- Testing
- L-Histidine, Lodosyn
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
Ischemic Stroke
Mild and Rapidly Improving Stroke Study
The objective of this study is to determine the 90-day outcomes of mild and rapidly improving ischemic stroke.
- Trial name
- MaRISS (NCT02072681)
- Where
- 97 sites in United States
- Volunteers
- 2,175 people
- Sponsor
- University of Miami
Prostate Cancer, Prostate Adenocarcinoma
MRI-Guided Lattice Extreme Ablative Dose Radiotherapy For Prostate Cancer
The hypotheses of this study are: 1. Delivery of single fraction Lattice Extreme Ablative Dose (LEAD) radiotherapy (RT) to the dominant tumor lesion(s) in the prostate as identified by multiparametric functional Magnetic…
- Trial name
- LEAD (NCT01411319)
- Testing
- Lattice Extreme Ablative Dose Radiation Therapy, Standard IMRT
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Miami
HIV/AIDS
90 DAYS: An Entertainment Education Intervention to Evaluate a Short Film About HIV Status Disclosure
This investigation seeks to understand if and how, the 90 Days film can be used as an intervention to address HIV-related stigmas, intimate partner status disclosure and HIV ART medical adherence among Black HIV positive women.
- Trial name
- NCT03898063
- Testing
- 90 DAYS film, HIV pamphlet on disclosure
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- University of Miami
Smoking Cessation
Addressing Racial/Ethnic Tobacco Health Disparities Via Group Intervention
The purpose of this study is to test the effects of a group smoking cessation program. The study will also examine individual differences in response to the intervention program.
- Trial name
- NCT02511236
- Testing
- Group Cognitive Behavioral Therapy, General Health Education, Transdermal Nicotine Patch
- Where
- 2 sites in United States
- Volunteers
- 356 people, healthy volunteers welcome
- Sponsor
- University of Miami
Quality of Life
Mohs Surgery: Patient Satisfaction & Quality of Life (QOL)
The purpose of this study is to examine whether there is significant difference between two groups: extra care (EC) and usual care (UC) in improvement of patients' quality-of-life (QoL) scores between the baseline and 90-day…
- Trial name
- NCT04936906
- Testing
- Extra Care (EC) Intervention, Usual Care (UC)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Miami
Liver Disease Chronic, Muscle Weakness
Inspiratory Muscle Training Post-Liver Transplant
Individuals with chronic liver disease develop significant muscle wasting that remains post-liver transplant. The transplant surgery additionally challenges respiratory mechanics.
- Conditions
- Liver Disease Chronic, Muscle Weakness, Respiratory Insufficiency
- Trial name
- NCT03130608
- Testing
- Inspiratory Muscle Training
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- University of Miami
Eyelid Droop
The Effect of Lumify™ Eyedrops on Eyelid Position
The purpose of the research is to see if Lumify™ has an effect on eyelid position.
- Trial name
- NCT03782701
- Testing
- Brimonidine tartrate ophthalmic solution 0.025%, Sterile balanced saline solution
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Miami
Coronavirus Infection, Type 2 Diabetes
Effects of DPP4 Inhibition on COVID-19
The purpose of this research is to see if the DPP4 inhibitor linagliptin, an oral medication commonly used to treat type 2 diabetes,can help with diabetes control and reduce the severity of the COVID-19 infection
- Trial name
- NCT04341935
- Testing
- Linagliptin, Insulin regimen
- Where
- United States
- Sponsor
- University of Miami
Crohn Disease, Ulcerative Colitis
Characterization of CD Responders to Vedolizumab
The purpose of this study is to characterize which patients with Crohn's disease are likely to respond to standard of care to vedolizumab therapy.
- Trial name
- NCT04909359
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Miami
Intracranial Vascular Disorders
Mechanisms of Early Recurrence in Intracranial Atherosclerotic Disease
The objective of this study is to determine the mechanisms of stroke in patients with Intracranial Atherosclerotic Disease (IAD) by specifically evaluating limitations of antegrade flow through the stenotic artery, distal tissue…
- Trial name
- MyRIAD (NCT02121028)
- Where
- 10 sites in United States
- Volunteers
- 105 people
- Sponsor
- University of Miami
Parkinson's Disease
Deep Brain Stimulation Effects on Gait and Balance in Patients With Parkinson's Disease
The purpose of this study is to evaluate the effect of Deep Brain stimulation (DBS) on walking in patients with Parkinson's disease that have had DBS.
- Trial name
- NCT02022735
- Testing
- Deep Brain Stimulator
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Miami
Sickle Cell Disease
Liver Fibrosis in Sickle Cell Disease
Patients with sickle cell disease many have a number of systemic complications, including liver problems. Some of these liver problems lead to liver fibrosis/cirrhosis, secondary to chronic blood transfusions.
- Trial name
- NCT02007746
- Testing
- Liver transient elastography (Fibroscan), Ferriscan, Liver biopsy in iron overloaded subjects.
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Miami
Deafness, Bilateral
Parent-Child Early Approaches to Raising Language Skills (PEARLS) Intervention
The purpose of this research study is to develop and evaluate a parent training program, which aims to improve language. The study is being conducted to see if teaching parents positive parenting techniques and behavior…
- Trial name
- PEARLS (NCT03260062)
- Testing
- Parent-Child Early Approaches to Raising Language Skills, Standard Care Speech therapy
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Miami
Caregiver Burnout
Asthma Academy: Use of Simulation and Telehealth to Empower Family Caregivers
The goal of this project is to implement and evaluate a novel intervention for low-income families to reduce the burden of caregivers of a child with asthma.
- Trial name
- NCT04132297
- Testing
- Asthma Academy, Telehealth Visit
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Miami