Clinical trials: sponsored by University of Miami
Optic Neuropathy
Biomechanics of Optic Neuropathy
The participant is being asked to be a subject in this research study because the participant may have a disorder that can cause optic nerve damage and impairment of his/her visual function which is called optic neuropathies…
- Trial name
- NCT02982499
- Testing
- magnetic resonance image (MRI), Optical Coherence Tomography (OCT)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Miami
Multiple Sclerosis
Histaminergic Basis of Central Fatigue in Multiple Sclerosis - A Novel Approach
The histaminergic system is phylogenetically one of the oldest parts of the nervous system but it is a relatively recent discovery.
- Trial name
- NCT03266965
- Testing
- Carbidopa, L-Histidine
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Miami
Monoclonal Gammopathies, Overweight
Antigen-Lipid-Driven Monoclonal Gammopathies Targeting Epicardial Fat
The purpose of this research study is to learn about the effect of Liraglutide (Victoza) on the fat of the heart and some fat cells in blood.
- Conditions
- Monoclonal Gammopathies, Overweight, Obesity
- Trial name
- NCT02920190
- Testing
- Liraglutide
- Sponsor
- University of Miami
Obesity, Pre Diabetes
Healthsnap on Epicardial Adipose Tissue Study
The purpose of this research study is to learn about the effectiveness of HealthSnap assessment, to reduce epicardial fat thickness.
- Trial name
- HEATS (NCT03683888)
- Testing
- HealthSnap, dietary counseling
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Miami
Relationship, Marital
Automated & Coached Web-based Programs to Improve and Strengthen Romantic Relationships
This study investigates the effectiveness of self-help, web-based programs to improve romantic relationships and related outcomes.
- Trial name
- NCT03568565
- Testing
- ePREP Program, OurRelationship Program
- Where
- United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- University of Miami
Melanoma
3-month Aerobic and Resistance Exercise Intervention for Individuals Diagnosed With Melanoma
Our proposed study will focus on addressing the feasibility, safety and benefits of a 3-month exercise intervention among individuals diagnosed with melanoma.
- Trial name
- NCT03825913
- Testing
- Exercise Intervention, Wellness Intervention
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Miami
COPD, Chronic Bronchitis
Effect of Losartan on Airway Mucociliary Dysfunction in Patients With COPD and Chronic Bronchitis
The purpose of this study is to evaluate the effect of Losartan on cigarette smoke-induced lung injury in smokers and ex-smokers with and without chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT02416102
- Testing
- Losartan 50 mg, Losartan 100 mg
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Miami
Well Aging
Mindfulness Training for Seniors
The purpose of this research study is to learn more about how mindfulness training may influence thinking and feeling.
- Trial name
- NCT04378803
- Testing
- Mindfulness training (MT) Connect
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Miami
Spinal Cord Injuries
Orthostatic, Respiratory, Balance-Intervention
The purpose of this study is to help understand how training breathing muscles will impact balance, blood pressure, and quality of life of participants with spinal cord injury.
- Trial name
- ORB-I (NCT04210063)
- Testing
- Inspiratory Muscle Training (IMT)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Miami
Acute Myelogenous Leukemia, Myelodysplastic Syndromes
Study of TCP-ATRA for Adult Patients With AML and MDS
Acute Myeloid Leukemia (AML) is a diverse disease that is fatal in the majority of patients. Acute promyelocytic leukemia (APL) however, a subtype of AML accounting for 5% of all cases, is very curable.
- Conditions
- Acute Myelogenous Leukemia, Myelodysplastic Syndromes, Leukemia
- Trial name
- TCP-ATRA (NCT02273102)
- Testing
- Tranylcypromine, Tretinoin
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Miami
Pain Management, Analgesia
Post-Operative Pain Management Following Spine Surgery
The primary objective of this pilot study is to assess the feasibility of comparing two standardized approaches to manage post-operative pain following spine surgery: one approach using Patient Controlled Analgesia (PCA) devices…
- Conditions
- Pain Management, Analgesia, Anesthetic
- Trial name
- EXPAREL (NCT03076710)
- Testing
- Opioids delivered through PCA, EXPAREL® infiltration
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
Parkinson's Disease
Transcranial Direct Current Stimulation for Freezing of Gait
This study will evaluate the effects of transcranial direct current stimulation (tDCS) in combination with locomotor training in patients with Parkinson's disease (PD) and freezing of gait (FOG).
- Trial name
- TDCS-FOG (NCT02266004)
- Testing
- Transcranial Direct Current Stimulation (tDCS), locomotor training
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Miami
Critical Illness, Intensive Care Unit Syndrome
Exercise With Music for ICU Survivors
This project will test whether the individualized music-enhanced exercise playlist (Exercise with Music intervention) can prevent further physical and psychological deterioration and motivate ICU survivors to more actively…
- Trial name
- NCT03885687
- Testing
- Exercise with Music, Exercise
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Miami
Brain Injuries, Traumatic
Testing Mild Traumatic Brain Injury (mTBI) in Diverse Athletic Groups
Study will test the use of a short virtual reality driven goggle test as a means of detecting mTBI in a diverse group of athletes
- Trial name
- NCT03515967
- Testing
- I-PAS Goggles
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
Cerebral Stroke
The Safety and Tolerability of an Aerobic and Resistance Exercise Program With Cognitive Training Post-stroke
It is estimated that 2 out of 3 patients with a stroke have some problems with their memory, difficulties performing certain tasks, making decisions and learning new things.
- Trial name
- NCT02272426
- Testing
- CARET, CTI
- Where
- 2 sites in United States
- Volunteers
- 132 people
- Sponsor
- University of Miami
Loneliness, Depression
Isolated During COVID-19: Effects of COVID-19's Social Restrictions on Loneliness and Psychosocial Symptomatology
This study seeks to gather data and insight on epidemiologic trends of loneliness and other behaviors in the wake of the CDC recommended "social distancing" during the COVID-19 pandemic.
- Conditions
- Loneliness, Depression, Anxiety, Alcohol Abuse
- Trial name
- NCT04440098
- Where
- United States
- Volunteers
- 1,008 people, healthy volunteers welcome
- Sponsor
- University of Miami
Spinal Cord Injuries
Energetic Response to Feeding and Exercise in SCI
This study investigates the effect of various forms of upper extremity exercise on postprandial glycemia and lipemia in persons with spinal cord injury (SCI).
- Trial name
- CRIT (NCT03545867)
- Testing
- Seated control (CON), Moderate intensity continuous (MICT), High intensity interval training (HIIT)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Miami
Pain
Use Of Virtual Reality For Pain Control in Dermatological Bedside Procedures
The purpose of this research study is to explore the impact of virtual reality (VR) on pain perception during out-patient procedures such as wart removal, wound debridement, and lidocaine injections.
- Trial name
- NCT04287491
- Testing
- Oculus Go Virtual Reality System
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
Ventricular Dysfunction, Pericardial Effusion
Focused Cardiac Ultrasound
To compare the images from standard cardiac ultrasound with images from a small hand-held device; to find out more about the feasibility and accuracy of a small hand-held ultrasound device.
- Conditions
- Ventricular Dysfunction, Pericardial Effusion, Valvular Disease, Septal Defect
- Trial name
- NCT03887286
- Testing
- Philips EPIQ 7 ultrasound machine, Philips Lumify Broadband sector array transducer
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of Miami
Vasculogenic Erectile Dysfunction
Safety and Efficacy of Low Intensity Shockwave for the Treatment of Erectile Dysfunction
Renova- Erectile Dysfunction (ED) is a Linear Shockwaves (LISW) device which incorporates a unique shockwave transducer operable to deliver shockwaves to a treated region.
- Trial name
- NCT03067987
- Testing
- Low Intensity Linear Shockwave Device for the Treatment of Erectile Dysfunction.
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- University of Miami