Clinical trials: sponsored by University of Miami
Aging, Skin Abnormalities
Efficacy of Polypodium Leucotomos Extract Decreasing UVA Premutagenic and Photoaging Markers
With this study, the investigators will like to determine if taking a dose of the study medication, called Polypodium leucotomos (PL), prevents some of the changes in the skin caused by the adverse effects of UVA, a type of…
- Trial name
- NCT00520910
- Testing
- Polypodium leucotomos
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Miami
Enlarged Prostate
3D Rotational CT Angiogram With Embolization Guidance and CBCT in Prostatic Artery Embolization
The purpose of this research study is to learn about how cone-beam Computerized Tomography scans (X-ray images taken from different angles) work together with an embolization guidance software (helps the doctor see the arteries…
- Trial name
- NCT03164629
- Testing
- cone-beam CT 3D Emboguide
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Miami
Type 2 Diabetes, Overweight
Effect of Liraglutide on Epicardial Fat in Subjects With Type 2 Diabetes
The purpose of this research study is to learn about the effect of Liraglutide, (Victoza®), on the fat surrounding the heart.Excessive amount of the fat around the heart is common in people with type 2 diabetes and can be…
- Conditions
- Type 2 Diabetes, Overweight, Obesity
- Trial name
- NCT02014740
- Testing
- Liraglutide, Metformin
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Miami
Coagulation Disorder
INR Comparison Testing in Cardiac Surgery
The investigator is testing blood samples to compare the results of two different techniques. Since blood loss and the need for blood transfusions continue to be major problems after heart surgery and other types of surgery, the…
- Trial name
- NCT03267823
- Testing
- International Normal Ratio (INR)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Miami
Corneal Injuries
Peri-operative Application of Eyeprotx General Anesthesia Goggles As Prevention Against Corneal Injury Post Intubation.
This is a randomized controlled trial that seeks to examine the effectiveness of Eyeprotx™ protective goggles in comparison to traditional methods against ocular injury that can occur perioperatively under general anesthesia.
- Trial name
- NCT03762889
- Testing
- Eyeprotx™ General Anesthesia Protective Goggles, Eyelid Tape, Eye Ointment
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
Headache
Neuromodulation Treatment of Vestibular Migraines
This is a non-randomized pilot study to test the efficacy of neuromodulation via caloric stimulation on vestibular migraines. All subject who meet the study criteria will be in an active treatment group.
- Trial name
- NCT02866084
- Testing
- Device
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
Wound
Doubleblinded RCT of the Omnilux on Lower Extremity Surgical Wounds Left to Heal by Second Intention
The goal of the study is to evaluate the effectiveness of the light-emitting diode (LED) in promoting healing of the wound on lower leg as a result of surgery.
- Trial name
- NCT02383056
- Testing
- Omnilux
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Miami
AIDS, Tuberculosis
Pharmacokinetic Study of Super-boosted Lopinavir/Ritonavir Given With Rifampin
The object of this study is to evaluate the pharmacokinetic interactions, short term safety and efficacy of standard dose lopinavir/ritonavir 200mg/50 (two tablets twice daily) given with ritonavir 100 mg three tablets twice…
- Trial name
- NCT01700790
- Testing
- Lopinavir/ritonavir and ritonavir
- Where
- Brazil
- Volunteers
- 9 people
- Sponsor
- University of Miami
Surgical Blood Loss, Spinal Surgery
Efficacy of Suction Enabled Retraction Device
This is a prospective randomized controlled trial of the Suction-Integrated Surgical Tissue Elevator \& Retractor [SISTER] device to assess: Effects on operative time and efficiency of exposure in open lumbar spine cases.
- Trial name
- NCT03160170
- Testing
- SISTER device
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Miami
Cigarette Smoking
Contingency Management for Smoking Cessation in Pregnant Minority Women
The long-term goal of this research is to reduce tobacco-related disparities in maternal and infant health outcomes by improving smoking cessation and relapse prevention interventions for minority pregnant and postpartum women…
- Trial name
- NCT02195570
- Testing
- Quit Smoking Now (QSN), Prize-based Contingency Management (CM)
- Where
- United States
- Sponsor
- University of Miami
Health Behavior, Health Knowledge, Attitudes, Practice
CircaHealth Development and Evaluation
This study evaluates the feasibility, acceptability, and efficacy of an online education course about circadian rhythms and health.
- Conditions
- Health Behavior, Health Knowledge, Attitudes, Practice, Circadian Rhythm
- Trial name
- NCT03835572
- Testing
- CircaHealth: a course on circadian rhythms and health, Sleep hygiene materials
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Miami
Cervical Cancer Screening
HPV Self-Sampling for Cervical Cancer Screening Among Transgender Men and Transmasculine Individuals
The proposed study will examine the implementation of a Human Papillomavirus (HPV) self-sampling intervention for unscreened and under-screened transgender men and transmasculine individuals living in South Florida.
- Trial name
- NCT03222817
- Testing
- HPV self-sampling
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Miami
Pneumothorax Iatrogenic Postprocedural
Gelfoam to Prevent Pneumothorax After Lung Biopsy
Lung cancer is the deadliest of all cancers, and its incidence is on the rise. The importance of accurate and efficient lung biopsy without complications will only increase in importance going forward.
- Trial name
- NCT03669003
- Testing
- Gelfoam slurry, CT-guided percutaneous lung biopsy
- Where
- 2 sites in United States
- Sponsor
- University of Miami
Breast Cancer, Metastatic Breast Cancer
Vinorelbine With Trastuzumab Emtansine in Pre-Treated HER2-Positive Metastatic Breast Cancer
The study proposes to evaluate the safety and efficacy of the combination of trastuzumab emtansine (T-DM1) and vinorelbine in HER2+ metastatic breast cancer patients.
- Trial name
- NCT02658084
- Testing
- Vinorelbine, Trastuzumab Emtansine
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Miami
Coronary Artery Disease
Epicardial Fat in Coronary Artery Disease
We hypothesize that human epicardial fat plays a thermogenic role to the myocardium. We hypothesize that epicardial fat may express genes of brown fat and thyroid function that are down-regulated by the presence of coronary…
- Trial name
- NCT03693261
- Testing
- Coronary artery bypass grafting (CABG), Valve replacement
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of Miami
HIV
HIV Prevention Toolkit for HIV-negative Male Couples
Though technology is integrated into the lives of our target population, use of any particular technology will depend on the content delivered, aesthetic appeal, and overall design.
- Trial name
- MCAP (NCT02494817)
- Testing
- Male Couples Agreement Project
- Where
- United States
- Volunteers
- 298 people, healthy volunteers welcome
- Sponsor
- University of Miami
Cancer
Interrogation of Wnt, Notch and Hedgehog Activity in Primary Tumor Samples
Cancer results when undifferentiated cells grow in an uncontrolled manner, crowding out normal cells, causing morbidity and ultimately mortality.
- Trial name
- NCT02006550
- Where
- United States
- Volunteers
- 227 people
- Sponsor
- University of Miami
Leiomyosarcoma
Trabectedin, Doxorubicin and Olaratumab in Patients With Metastatic or Recurrent Leiomyosarcoma
This study seeks to determine if addition of trabectedin (T) to combination doxorubicin (D) and olaratumab (O), is feasible and tolerable with antitumor activity in metastatic or recurrent Leiomyosarcomas (LMS) patients who have…
- Trial name
- NCT03437070
- Testing
- Trabectedin, Doxorubicin, Olaratumab
- Sponsor
- University of Miami
Keloid
A Randomized Clinical Study Comparing Two Closure Techniques of Excised Keloids
This investigator initiated study, single-blinded, parallel, randomized study will be conducted in subjects with 2 or more keloids similar in size and duration on a similar area of the body.
- Trial name
- NCT00519493
- Testing
- Suture, Clozex
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Miami
Pediatric Obesity, Obesity
Healthy Caregivers-Healthy Children (HC2) Phase II
One in four U.S. children under the age of 5 years old are either overweight or obese with ethnic-minority children being disproportionately affected.
- Trial name
- NCT02697565
- Testing
- Healthy Caregivers- Healthy Children Toolkit, Safety Curriculum
- Where
- United States
- Volunteers
- 2,289 people
- Sponsor
- University of Miami