Clinical trials: sponsored by University of Miami
Pediatric Obesity, Obesity
Healthy Caregivers-Healthy Children (HC2) Phase II
One in four U.S. children under the age of 5 years old are either overweight or obese with ethnic-minority children being disproportionately affected.
- Trial name
- NCT02697565
- Testing
- Healthy Caregivers- Healthy Children Toolkit, Safety Curriculum
- Where
- United States
- Volunteers
- 2,289 people
- Sponsor
- University of Miami
Diabetes Mellitus
AchE Inhibitor and Insulin
The investigator will examine the effect of a single dose of pyridostigmine, AchE inhibitor on insulin secretion in healthy subjects.
- Trial name
- AchE (NCT03063515)
- Testing
- Pyridostigmine
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Miami
HIV, Pregnancy
Implementing a Comprehensive Prevention of Mother-to-Child Transmission of HIV Program for South African Couples
This study will test the effectiveness of a behavioral intervention to increase Prevention of Mother-to-Child Transmission of HIV (PMTCT) protocol uptake among South African HIV positive pregnant women.
- Trial name
- NCT02085356
- Testing
- Protect your family
- Where
- South Africa
- Volunteers
- 1,967 people
- Sponsor
- University of Miami
Acne
Study Assessing the Effect of Chocolate Consumption in Subjects With A History of Acne Vulgaris
The investigators conducted a recent pilot study and found a strong positive correlation between the consumption of 100% chocolate and acne exacerbation.
- Trial name
- NCT01193764
- Testing
- 100% cocoa powder, gelatin (Gelita)
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Miami
Burnout, Professional, Stress
Mindfulness Training for Medical Personnel
In this project, the investigators propose to evaluate the impact of a Mindfulness-Based Intervention (MBI) Program on the well-being of University of Miami (UM) clinicians and faculty/staff.
- Trial name
- NCT03514862
- Testing
- Mindfulness Booster Training, Mindfulness-Based Intervention (MBI), Self-Practice
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Miami
Social Isolation, Social Support (Formal and Informal)
A Personalized Reminder Information and Social Management System
Although technology offers great potential for enhancing the health and well-being of older adults, robust studies are needed to quantify the value of technology and further the investigators understanding of barriers to…
- Conditions
- Social Isolation, Social Support (Formal and Informal), Well-being/Quality of Life
- Trial name
- PRISM (NCT01497613)
- Testing
- PRISM C: Computer Condition, PRISM B: Notebook Condition
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Miami
Esophageal Cancer
Wnt, Notch and Hedgehog Activity in Chemo-Naive Tumors Collected During Staging of Esophageal Cancer Patients
Cancer results when undifferentiated cells grow in an uncontrolled manner, crowding out normal cells, causing morbidity and ultimately mortality.
- Trial name
- NCT02221245
- Testing
- Tumor Biopsy via Ultrasound Endoscopy
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Miami
Amyotrophic Lateral Sclerosis
Phase II/III Randomized, Placebo-controlled Trial of Arimoclomol in SOD1 Positive Familial Amyotrophic Lateral Sclerosis
The purpose of this study will be to demonstrate the safety, tolerability, and efficacy of arimoclomol in subjects with SOD1 positive familial Amyotrophic Lateral Sclerosis (ALS).
- Trial name
- NCT00706147
- Testing
- Arimoclomol
- Where
- 2 sites in United States
- Volunteers
- 38 people
- Sponsor
- University of Miami
Spinal Cord Injury
Hypothermia Following Acute Spinal Cord Injury
The purpose of this study is to investigate the long term outcome of patients who receive hypothermia treatment for spinal cord injury.
- Trial name
- NCT01739010
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of Miami
Romantic Relationship
Web-based Programs to Improve and Strengthen Romantic Relationships
This study investigates the effectiveness of www.OurRelationship.com, which provides self-help, web-based programs to improve romantic relationships and related outcomes.
- Trial name
- NCT02806635
- Testing
- OurRelationship, PREP Online
- Where
- United States
- Volunteers
- 1,484 people, healthy volunteers welcome
- Sponsor
- University of Miami
Lentigo Maligna, Melanoma In Situ
Mohs and Immunofluorescence for Malignant Melanoma In Situ
The purpose of this study is to determine if immunofluorescence (IF) can effectively identify features of malignant melanoma in situ, on sun-damaged skin, in the setting of Mohs Micrographic Surgery.
- Trial name
- NCT02306512
- Testing
- H&E, IHC MART-1, IF MART-1
- Where
- 2 sites in United States
- Sponsor
- University of Miami
Substance-Related Disorders, Mental Health
SET-Recovery/Healthy Home
The study conducts a community-based randomized trial comparing an adaptation of Structural Ecosystems Therapy (SET), "Healthy Home", as an enhancement of substance abuse or mental health outpatient treatment, to outpatient…
- Trial name
- SET-R (NCT02702193)
- Testing
- SET-R/Healthy Home
- Where
- United States
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- University of Miami
Cervical Cancer
Using CHWs or Mailing Self Sampling Home Tests to Increase Cervical Cancer Screening in South Florida
The study will test the significance of community health worker (CHW) participation by comparing self-sampling provided by a community health worker and self-sampling provided by mail.
- Trial name
- NCT02202109
- Testing
- CHW and Self-sampling for Cervical Cancer, Mailed Self Sampler
- Where
- United States
- Volunteers
- 602 people
- Sponsor
- University of Miami
Chronic Fatigue Syndrome
Patient-Partner Stress Management Effects on Chronic Fatigue Syndrome Symptoms and Neuroimmune Process
The purpose of this study is to test the effects of a videotelephone-delivered patient-partner dual-focused cognitive behavioral stress management intervention on chronic fatigue syndrome (CFS) symptoms and related psychosocial…
- Trial name
- NCT01650636
- Testing
- Patient-Partner Videotelephone-delivered Health Information (PP-T-HI), Patient-Partner Videotelephone-delivered Cognitive Behavioral Stress Management intervention (PP-T-CBSM)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Miami
Anxiety Disorders, Depression
Unified Protocol for Adolescents (UP-A) Change Processes
The purpose of this protocol is to employ single case analytic strategies, including a multiple baseline design and novel modeling techniques to identify changes in cross-cutting features of emotional disorders as well as…
- Conditions
- Anxiety Disorders, Depression, Obsessive-Compulsive Disorder, Adolescent - Emotional Problem
- Trial name
- NCT03102008
- Testing
- Unified Protocol for Emotional Disorders in Adolescents (UP-A)
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Miami
Cervical Cancer
Using CHWs and HPV Home Tests to Increase Cervical Cancer Screening in Minority Populations
Caribbean immigrants (both Hispanics and Blacks from Haiti) are less likely to be screened for cervical cancer than the general population.
- Trial name
- SUCCESS (NCT02121548)
- Testing
- CHW Outreach and HPV Self-sampling, CHW Outreach
- Where
- United States
- Volunteers
- 601 people, healthy volunteers welcome
- Sponsor
- University of Miami
Diabetes, Heart Disease
Miami Healthy Heart Initiative a Behavioral Study on Cardiovascular Risk Factors
A study to examine the effectiveness of a multilevel Community Health Workers intervention as an adjunct to routine primary care in reducing CVD risk factors among diabetic Latinos in Miami.
- Conditions
- Diabetes, Heart Disease, Hypertension
- Trial name
- MHHI (NCT01152957)
- Testing
- CARIÑO Project, Enhanced Usual Care
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Miami
Spinal Cord Injury
Examining the Distal Gut Microbiome After Spinal Cord Injury
The purpose of this research study is to learn more about the causes of gastrointestinal dysfunction after spinal cord injury. It has been thought that the microbiome (the community of bacteria in the body) may be one such cause.
- Trial name
- NCT03319225
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Miami
Spinal Cord Injury
Vagal Nerve Stimulation to Reduce Inflammation and Hyperadrenergia
The purpose of this research device study is to learn more about the autonomic nervous system. This system uses nerves to send information from the brain to the rest of the body by electrical signaling and has two divisions, the…
- Trial name
- NCT02983266
- Testing
- InTENsity MicroCombo
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
Nodular Basal Cell Carcinoma, Superficial Basal Cell Carcinoma
Randomized Pilot Study of Treatment for BCC Using the Multiplex 595/1064 nm Laser
Laser therapy for basal cell carcinoma may be a superior option for patients who do not wish to or cannot tolerate other treatment modalities such as topical chemotherapeutics or surgery.
- Trial name
- BCC (NCT02270645)
- Testing
- 595/1064 multiplex laser
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Miami