Clinical trials: sponsored by University of Miami
Cancer, Walking
Hematopoetic Stem Cell Transplant and Physical Function
This study will determine if a structured walking intervention will help maintain or improve physical activity levels, physical function and quality of life in hematopoietic stem cell transplant patients.
- Trial name
- HSCT (NCT03103308)
- Testing
- Walk Training and Transplant, Activity Monitoring and Transplant
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Miami
Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma
Prospective Trial of Serial CT Imaging for Evaluation of Dosimetric/Volumetric Changes During IMRT for Head/Neck Cancer
Anatomical changes that take place during Intensity modulated radiation therapy (IMRT) treatments for cancers of the head and neck cause significant dosimetric changes.
- Trial name
- NCT02003482
- Testing
- Postop IMRT for head/neck cancer, CT for Radiation Treatment Planning
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Miami
Healthy
Topical Imiquimod in Conjunction With Nd:YAG Laser for Tattoo Removal
The purpose of this study is to evaluate the efficacy of tattoo removal using topical imiquimod, 5% cream in conjunction with the 1064nm Nd:YAG laser. This procedure for tattoo removal will be compared to a laser removal alone.
- Trial name
- NCT00638651
- Testing
- 1064 nm Nd:YAG laser, Imiquimod, 5% cream
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Miami
Anosmia
NAC Trial for Anosmia
The purpose of this research study is to evaluate the use of NAC in the treatment of anosmia (a loss of the sense of smell). This drug is already approved by the Food and Drug Administration (FDA) for oral or pulmonary (lung)…
- Trial name
- NCT02481609
- Testing
- N-acetyl cysteine (NAC)
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Miami
Sleep Apnea, Obstructive, Total Knee Arthroplasty
Obstructive Sleep Apnea in Elective Orthopaedic Surgery
Demand for Total Knee Arthroplasty (TKA) and Total Hip Arthroplasty (THA) is increasing steadily and is projected to continue trending upwards in the coming years.
- Conditions
- Sleep Apnea, Obstructive, Total Knee Arthroplasty, Total Hip Arthroplasty
- Trial name
- NCT03166462
- Testing
- Evaluation by Sleep Medicine Specialists
- Where
- United States
- Sponsor
- University of Miami
Relationship, Marital, Marital Conflict
Empirically-Based Couple Interventions on the Web: Serving the Underserved
Although several empirically-supported interventions to prevent and treat relationship distress have been developed, the majority of couples - especially high-risk couples - do not seek these face-to-face interventions.
- Trial name
- NCT03292692
- Testing
- OurRelationship
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Miami
Primary Sclerosing Cholangitis
Pilot Study of Fenofibrate for PSC
The purpose of this study is to determine whether fenofibrate is safe and effective in the treatment primary sclerosing cholangitis (PSC).
- Trial name
- NCT01142323
- Testing
- fenofibrate
- Where
- 2 sites in United States
- Volunteers
- 8 people
- Sponsor
- University of Miami
Relapsing Remitting MS, Secondary Progressive MS
Caprylic Triglyceride for Treatment of Cognitive Impairments in Multiple Sclerosis
Background/Rationale: Cognitive problems are a common symptom in individuals with Multiple Sclerosis (MS). Treatment options are limited, and there is a pressing need for new interventions to treat MS-related cognitive…
- Conditions
- Relapsing Remitting MS, Secondary Progressive MS, Primary Progressive MS
- Trial name
- NCT01848327
- Testing
- Caprylic Triglyceride
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- University of Miami
Cholangiocarcinoma, Biliary Tract Cancer
A Study of Combination of Gemcitabine, Oxaliplatin (GEMOX)-Sorafenib in Patients With Advanced Biliary Tract Cancer
The purpose of this study is to build on the efficacy of the GEMOX regimen by adding Sorafenib in the treatment of Biliary Tract Cancer.
- Conditions
- Cholangiocarcinoma, Biliary Tract Cancer, Gallbladder Cancer
- Trial name
- NCT00955721
- Testing
- Gemcitabine, Oxaliplatin, Sorafenib
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Miami
Breast Cancer
NOV-002, Doxorubicin, Cyclophosphamide, and Docetaxel in Women With Newly Diagnosed Stage II or IIIC Breast Cancer
RATIONALE: Oxidized glutathione (NOV-002) may stimulate the immune system in different ways and stop tumor cells from growing. Drugs used in chemotherapy, such as doxorubicin, cyclophosphamide, and docetaxel, work in different…
- Trial name
- NCT00499122
- Testing
- Cyclophosphamide, Docetaxel, Doxorubicin
- Where
- 2 sites in United States
- Volunteers
- 41 people
- Sponsor
- University of Miami
Parkinson's Disease
A Randomized Trial to Evaluate Ampyra for Gait Impairment in Parkinson's Disease
The purpose of this study is to evaluate the effect of AMPYRA on a number of symptoms in Parkinson's disease. AMPYRA is a medication approved by FDA for gait dysfunction in multiple sclerosis.
- Trial name
- NCT01491022
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Miami
Liver Cancer, Hepatic Tumors
Follow-up Yttrium-90 Internal Pair Production PET/CT vs Brehmsstrahlung Imaging in Patients With Primary/Metastatic Liver Tumors
This is a prospective non-blinded case series involving the acquisition of a pair production PET/CT as soon as possible after an already performed Y-90 Sirspheres treatment of hepatic malignancy.
- Trial name
- NCT02202317
- Testing
- PET/CT Scan
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Miami
Mild Traumatic Brain Injury, Brain Concussion
Testing mTBI in Athletes
This study will assess the effectiveness of a portable goggle system in the diagnosis of mild traumatic brain injury (mTBI) in athletes.
- Trial name
- NCT02486003
- Where
- United States
- Volunteers
- 329 people, healthy volunteers welcome
- Sponsor
- University of Miami
Non-Small Cell Lung Cancer, NSCLC
Safety of LEAD Radiotherapy Plus Chemoradiation in Patients With Bulky Stage III Non-Small Cell Lung Cancer
The investigators aim to evaluate the safety of delivering a one-time single fraction of Lattice Extreme Ablative Dose (LEAD) radiotherapy followed one day later by standard-dose, conventionally fractionated concurrent…
- Trial name
- NCT01797471
- Testing
- Lattice Extreme Ablative Dose (LEAD) Radiation Therapy
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Miami
Lymphoma, Follicular Lymphoma
Rituximab, Cyclophosphamide, Bortezomib, and Prednisone in Patients With Stage III/IV FL or MZL
RATIONALE: Monoclonal antibodies, such as rituximab, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread.
- Conditions
- Lymphoma, Follicular Lymphoma, Marginal Zone Lymphoma
- Trial name
- NCT00772668
- Testing
- Rituximab, Bortezomib, Cyclophosphamide
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Miami
Pancreatic Cancer
Capecitabine and Docetaxel in Treating Patients With Recurrent or Progressive Metastatic Pancreatic Cancer
RATIONALE: Drugs used in chemotherapy, such as capecitabine and docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00290693
- Testing
- Capecitabine, Docetaxel
- Where
- 3 sites in United States
- Volunteers
- 45 people
- Sponsor
- University of Miami
Suture Strabismus Surgery
Suture Contamination Rate in Adjustable Suture Strabismus Surgery
1. To establish the culture positivity rate in adjustable suture strabismus surgery 2. To identify bacterial species and antibiotic susceptibility patterns of microorganisms cultured from suture material 3.
- Trial name
- NCT02424357
- Testing
- 5%povidone iodine ophthalmic solution, routine post-operative ophthalmic ointment
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of Miami
COPD
Effect of Roflumilast on Airway Blood Flow as an Expression of Airway Inflammation in COPD
The objectives of the proposed study are to determine 1) the effect of a single dose of Roflumilast on airway blood flow (Qaw) (study period 1) and 2) the effect of long-term Roflumilast treatment on airway blood flow reactivity…
- Trial name
- NCT02097992
- Testing
- Roflumilast
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Miami
Asthma
Acute Effect of Mometasone on Beta-adrenergic Airway and Airway Vascular Relaxation in Severe Asthma
Glucocorticosteroids inhibit the disposal of organic cations by blocking organic cation transporters expressed by non-neuronal cells, thereby interfering with the inactivation of the organic cations by intracellular enzymes.
- Trial name
- NCT01210170
- Testing
- mometasone 400 mcg, mometasone 200 mcg
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Miami
Obesity, Physical Activity
Associations of Cognition, Fitness, and Body Composition Among Ethnic Minority Youth
Cognitive Control is crucial for learning and development. This study examined the associations between cognitive control and physical fitness and body composition among ethnic minority children.
- Conditions
- Obesity, Physical Activity, Cognitive Function 1, Social
- Trial name
- NCT03342924
- Testing
- Flanker Test and physical fitness test
- Where
- United States
- Volunteers
- 212 people
- Sponsor
- University of Miami