Clinical trials: sponsored by University of Miami
Bipolar Disorder, Cocaine Dependence
Valproate Efficacy in Cocaine-Bipolar Comorbidity
This proposal will test the efficacy of a promising pharmacological approach for the treatment of comorbid cocaine dependence and bipolar disorder.
- Trial name
- NCT00240110
- Testing
- Valproate, Lithium Carbonate
- Where
- 2 sites in United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of Miami
Heart Failure
A Novel Fully Integrated Mobile Management Solution Using Cell Phone Technology for Heart Failure
The purpose of this research study is to learn about the use of a cell phone for monitoring patients with heart failure. Participants will be asked questions about their heart failure daily and participants will need to answer…
- Trial name
- NCT02935439
- Testing
- Cell Phone
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- University of Miami
Unipolar Major Depression, Stage I, II or III Breast Cancer
Vortioxetine for MDD, Cognition, and Systemic Inflammatory Biomarkers
The purpose of this antidepressant study is to determine the efficacy of vortioxetine on depression and cognition in 80 women with breast cancer, and to elucidate inflammatory-mediated mechanisms by which depression and its…
- Trial name
- NCT02637466
- Testing
- Vortioxetine
- Sponsor
- University of Miami
Low Back Pain
Low Back Pain and Breathing Pattern Dysfunction
The goal of this study is to identify if there is a significant prevalence of abnormal respiratory patterns in a sample of patients with low back pain (LBP), and if the presence of abnormal respiratory patterns are predictive of…
- Trial name
- LBP&BPD (NCT02429752)
- Testing
- Inspiratory muscle training
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Miami
Healthy, Smokers
Effect of Whole Body Periodic Acceleration on Airway Endothelial Function
In the present proposal the investigators wish to assess the effect of a single session with the device known as Exer-Rest® which applies Whole Body Periodic Acceleration (WBPA) on baseline airway blood flow (Qaw) and in Qaw…
- Conditions
- Healthy, Smokers, Asthma
- Trial name
- NCT01213706
- Testing
- Whole Body Periodic Acceleration (WBPA)
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Miami
Ovarian Cancer, Ovarian Carcinoma
LDFWART With Docetaxel in Patients With Platinum-Resistant Recurrent Ovarian Carcinoma
The ultimate clinical aim of this proposed phase I trial is to evaluate the toxicity and determine the recommended phase II dose of combining the effect of LDFWART following administration of docetaxel for 6 cycles in patients…
- Conditions
- Ovarian Cancer, Ovarian Carcinoma, Recurrent Ovarian Cancer, Recurrent Ovarian Carcinoma
- Trial name
- NCT02083536
- Testing
- Low Dose Fractionated Whole Abdominal Radiation Therapy, Docetaxel
- Sponsor
- University of Miami
Overweight, Obesity
Enhanced Primary Care and Technology for Children With Chronic Disease
Using technology alongside a pediatric chronic disease specialist and behavior specialist, the investigators are planning to help care for and coordinate the healthcare of children with chronic diseases, particularly childhood…
- Conditions
- Overweight, Obesity, Asthma
- Trial name
- NCT02490566
- Testing
- Telehealth
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Miami
Human Immunodeficiency Virus Infection
The Effect of an Enhanced Rice Bran Nutritional Supplement in HIV
The purpose of this study is to investigate the effects of the nutritional supplement rice bran arabinoxylan compound (RBAC) on metabolic syndrome variables in persons living with HIV.
- Trial name
- BRM4 (NCT02214173)
- Testing
- rice bran arabinoxylan compound (RBAC)
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of Miami
Asthma
Interactive Acute Smooth Muscle Effects of Salmeterol and Fluticasone in the Airway
The addition of an inhaled long-acting beta-adrenergic agonist to an inhaled glucocorticosteroid improves disease control in persistent asthma.
- Trial name
- NCT01231230
- Testing
- fluticasone, Salmeterol, fluticasone/salmeterol
- Volunteers
- 14 people
- Sponsor
- University of Miami
Tobacco Abuse Smoke
Effect of an Inhaled Glucocorticosteroid (ICS) on Endothelial Dysfunction in Cigarette Smokers
The hypothesis underlying the proposed study is that the blunted endothelium-dependent vasodilation seen in the airway of current smokers is also present in the brachial artery, and that the same inhaled corticosteroid (ICS)…
- Trial name
- NCT01216735
- Testing
- Fluticasone
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Miami
Cicatrix, Scars
Study of the Effects of the Pulsed-dye Laser at 585nm and 595nm to Treat Post-operative Scars on Suture-removal Day
The purpose of this study is to compare the effects of the pulsed-dye laser (PDL) at two different wavelengths, 585nm and 595nm, in the treatment of post-surgical scars starting on suture-removal day.
- Trial name
- NCT00482144
- Testing
- PDL 450 microseconds, PDL 1.5 milliseconds
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Miami
Diabetes Mellitus, Type 2, Kidney Failure, Chronic
Study of the Use of Niaspan for Treatment of Dyslipidemia in Diabetic Nephropathy
The primary purpose of this study is to test the effectiveness and tolerability of Niaspan® to improve the levels of blood fats ("good" and "bad" cholesterol and triglyceride levels) in people who have kidney damage due to…
- Conditions
- Diabetes Mellitus, Type 2, Kidney Failure, Chronic, Hyperlipidemia
- Trial name
- NCT00108485
- Testing
- Extended release niacin
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Miami
Prostate Cancer, Pain
A Phase I/II Study of Azacitidine, Docetaxel, and Prednisone for Metastatic Prostate Cancer Patients
Azacitidine can reverse clinical resistance to docetaxel through upregulation of Growth Arrest and DNA Damage inducible alpha (GADD45α) and other epigenetically regulated genes.
- Trial name
- NCT00503984
- Testing
- Azacitidine, Docetaxel, Prednisone
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Miami
Healthy Volunteers
Clinical Evidence of pH Dependent ß2 Adrenergic Transport Mechanisms in the Airway
The purpose of this study was to determine if airway pH has an effect on albuterol-induced vasodilation in the airway. Methods: Ten healthy volunteers performed the following respiratory maneuvers: quiet breathing, hypocapnic…
- Trial name
- NCT01216748
- Testing
- quiet breathing, Hypocapnic Hyperventilation, Hypercapnic Hyperventilation
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Miami
Bipolar Disorder, Alcohol Dependence
Optimizing Pharmacotherapy for Bipolar Alcoholics
The purpose of this study is to test the efficacy of naltrexone and valproate in the treatment of comorbid bipolar disorder and alcohol dependence.
- Trial name
- NCT00302133
- Testing
- Naltrexone hydrochloride
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Miami
Neoplasm, Sepsis
Gorbly Compression Device for Use in Image-guided Procedures
Prospective cohort study. All patients presenting for percutaneous abdomino-pelvic soft tissue ablation, biopsy, or drainage performed under the care of Dr. Issam Kably will become part of the study population.
- Trial name
- NCT02578667
- Testing
- Gorbly Compression Device
- Where
- United States
- Sponsor
- University of Miami
Parkinson's Disease, Sleep Disordered Breathing
Sleep Disordered Breathing and Its Impact on Neuro-cognitive Performance and Quality of Life in Parkinson Disease
The purpose of this study is to determine the impact of sleep and breathing problems during sleep on memory, attention, and general well being (quality of life) in people with Parkinson Disease.
- Conditions
- Parkinson's Disease, Sleep Disordered Breathing, Sleep Obstructive Apnea
- Trial name
- NCT02034357
- Testing
- Neurocognitive function, Sleep evaluations
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- University of Miami
Spinal Cord Injury
Cardiometabolic Risk, Obesity and Cardiovascular Disease in People With Spinal Cord Injury
The purpose of this study is to develop and field-test new tools for diagnosis and hazard assessment of cardiometabolic risk (CMR) in people with chronic spinal cord injury (SCI) and to advance the evidence base with much needed…
- Trial name
- NCT01204632
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of Miami
Asthma
HealthSpark 2: Improving Asthma Care for Preschool Children
From a previous community needs survey, we determined that asthma was a particular problem in our community-based research network of child care centers.
- Trial name
- NCT00304304
- Testing
- Asthma education
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Miami
Dyslipidemia
Improving Adherence to Statins Among Minority Populations
Statins are cholesterol lowering medications that reduce the risk of cardiovascular events. However adherence to these medications has been found to be lower among minorities, a group particularly vulnerable for heart disease.
- Trial name
- NCT02037685
- Testing
- Motivational Interviewing (MINT), Usual Care
- Where
- United States
- Volunteers
- 779 people
- Sponsor
- University of Miami