Clinical trials: sponsored by University of Miami
Anxiety Disorders, Depression
A Waitlist-Controlled Trial of the Unified Protocol for the Treatment of Emotional Disorders in Adolescents
This study will evaluate the effectiveness of an emotion-focused cognitive behavioral treatment program for adolescents with anxiety or unipolar depressive disorders.
- Trial name
- NCT00628888
- Testing
- Unified Protocol for Adolescents (UP-A)
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Miami
ADHD, Conduct Disorder
Preventing Health Disparities in Hispanic Youth
This study seeks to investigate the efficacy and mechanisms of a highly promising "Culturally Informed Family Therapy for Adolescents" in preventing the emergence of two important health disparities in Hispanic youth, namely drug…
- Conditions
- ADHD, Conduct Disorder, Depression, Family Dysfunction
- Trial name
- CIFFTA-P (NCT02318745)
- Testing
- Culturally Informed Family Treatment for Adolescents, Individual Treatment
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Miami
Traumatic Brain Injury
Vasopressin Versus Catecholamines for Cerebral Perfusion Pressure Control in Brain Injured Trauma Patients
Traumatic brain injury (TBI) is among the leading causes of trauma death and disability in both civilian and military populations.
- Trial name
- AVP (NCT00795366)
- Testing
- arginine vasopressin, Standard catecholamine
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- University of Miami
Prostate Cancer, Prostate Adenocarcinoma
Trial of Prostate Cancer Patients Undergoing Active Surveillance With or Without MRI-Guided Management
1. Using multiparametric MRI Ultrasound-guided or MRI-guided biopsies will allow more accurate sampling of the tumors and therefore will increase the rate of "progression" on early (first and second) surveillance biopsies and…
- Trial name
- MGM (NCT01838265)
- Testing
- Transrectal Ultrasound-Guided Biopsy, MRI Ultrasound Biopsy, Expanded Prostate Cancer index Composite Questionnaire
- Where
- United States
- Sponsor
- University of Miami
Bipolar Disorder
Paliperidone Palmitate Efficacy and Safety in Bipolar Disorder Complicated by Alcoholism
The primary specific aim is to examine the efficacy of Paliperidone extended release Paliperidone Palmitate Injection (INVEGA® SUSTENNA™) compared to placebo in decreasing manic symptoms in patients with comorbid DSM-IV bipolar…
- Trial name
- NCT01211704
- Testing
- Paliperidone Palmitate
- Sponsor
- University of Miami
Type 2 Diabetes Mellitus
Effects of Pioglitazone on High-density Lipoprotein (HDL) Function in Persons With Diabetes
Metabolic defects contributing to the development of type 2 diabetes (T2D) are relative insulin insufficiency and insulin resistance that are associated with a cluster of abnormalities that increase the risk for cardiovascular…
- Trial name
- NCT01156597
- Testing
- pioglitazone
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Miami
Transplant; Failure, Kidney
Desensitization Protocol for Deceased Donor List
Purpose of the study: The specific aims of this study are to evaluate overall efficacy and safety of the pre-transplant IVIG treatment in our transplant center since 2007 and to identify factors affecting treatment outcomes in…
- Trial name
- NCT01642225
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of Miami
Uveitic Cystoid Macular Edema
Pilot Study of Ranibizumab (Lucentis) for Uveitic Cystoid Macular Edema
Uveitic Cystoid Macular Edema (CME) is a major cause of visual loss associated with uveitis. Systemic and/or local corticosteroid therapy and systemic immunosuppression with steroid-sparing agents such as cyclosporine…
- Trial name
- NCT00826618
- Testing
- ranibizumab
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- University of Miami
Phenylketonuria, Galactosemia
The Early History of Universal Screening for Metabolic Disorders
We are doing this study to learn more about the early history of universal screening for metabolic disorders such as PKU and galactosemia.
- Conditions
- Phenylketonuria, Galactosemia, Inborn Errors of Metabolism
- Trial name
- NCT00309400
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Miami
Hypothermia
Safety Study to Evaluate the Effect of Lowering Body Temperature During Cochlear Implantation
Hypothesis: Mild Hypothermia has a protective effect on residual hearing of patients undergoing cochlear implantation
- Trial name
- NCT00375882
- Testing
- hypothermia, cochlear implantation with mild hypothermia
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Miami
Sub-optimal Cognitive Function, Sub-optimal Immune Function
Evaluating Whole Foods Supplementation on Cognition
A six-month study which investigated the effect of Ginkgo Synergy® and Choline or OPC Synergy® and Catalyn® on cognitive and immune function markers and quality of life among healthy older adults with no history of significant…
- Trial name
- NCT01672359
- Testing
- Ginkgo Synergy® and Choline, OPC Synergy® and Catalyn
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- University of Miami
Depression
The Effect of Methylated Vitamin B Complex on Depression
The proposed study is a 60-day, randomized, double-blind, placebo-controlled trial to evaluate the efficacy of a methylated vitamin B complex nutritional supplement (Max Stress B™) for improving depressive and anxiety symptoms…
- Trial name
- NCT01672372
- Testing
- Max Stress B
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Miami
COPD
Effect of an Inhaled Glucocorticoid-long-acting Beta Adrenergic Agonist on Endothelial Function in COPD
In the present study, the investigators wish to address the effect of a glucocorticoid/long-acting beta-agonist preparation on endothelial function in COPD patients who do not currently smoke (ex-smokers) by measuring…
- Trial name
- NCT01209715
- Testing
- Fluticasone /salmeterol
- Where
- United States
- Sponsor
- University of Miami
Spinal Cord Injury
Wheelchair Mobility Assessment of Individuals With Spinal Cord Injury
The specific aims of this study are: 1) to assess the test-retest reliability of a modification of an existing wheelchair propulsion assessment and 2) validate the modification against traditional measures of physical strength…
- Trial name
- NCT01204047
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of Miami
Spinal Cord Injury
Acute Tendon and Nerve Responses to Exercise
The purpose of this study is to use ultrasound to analyze the effects of a bout of circuit training on the upper extremity of persons with spinal cord injury and able-bodied controls.
- Trial name
- NCT01197599
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Miami
Spinal Cord Injury
6 Minute Propulsion Test Sensitivity to Increased Aerobic Capacity
The goals of this project are to 1)determine the responsiveness of the 6 Minute Push Test (6MPT) and 2) explore the relationship between 6MPT distance and measures of handicap, wheelchair satisfaction, depression, and…
- Trial name
- NCT01184729
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Miami
Spinal Cord Injury
6 Minute Push & 30 Second Sprint Tests Reliability & Relationship to Fitness, Participation, & Environmental Assessments
The purpose of this study is to assess the relationship between physical fitness and wheelchair mobility capacity and 1) participation; 2) self-reported environments barriers; and 3) self-reported avoidance of environmental…
- Trial name
- NCT01184742
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of Miami
Spinal Cord Injury, Tetraplegia
Effects of Exercise in People With Tetraplegia
This study is designed to assess the impact of exercise and supplementation on measures of fitness, function, and cardiovascular disease risk factors/modifiers in individuals with spinal cord injury (SCI).
- Trial name
- NCT01202019
- Testing
- Circuit Resistance Training (CRT)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Miami
Healthy
Characterization of the Edge of Soft Contact Lens and Its Interaction With Ocular Surface
The goal of this study is to look at contact lens on the eye and its interaction with the eye during wearing.
- Trial name
- NCT00707291
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Miami
Glaucoma, Intraocular Pressure
The Measurement of Intraocular Pressure in Normal Children Under General Anesthesia With and Without Nitrous Oxide and Anesthetic Eye Drops
Pediatric glaucoma is a rare but potentially blinding condition where the pressure in the eye is too high. Diagnosis is based on intraocular pressure (IOP) and assessment of the optic nerve, cornea and other structures.
- Conditions
- Glaucoma, Intraocular Pressure, Anesthesia
- Trial name
- IOP (NCT01925391)
- Testing
- Tono-pen XL Applanation tonometer + Ocu-film +
- Where
- 2 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Miami