Clinical trials: sponsored by University of Miami
Type 2 Diabetes and Depression
Biobehavioral Bases & Management of Type 2 Diabetes
The major objective of this project is to determine if compared to Standard Care (SC), a Community Approach to Lifestyle Modification for Diabetes (CALM-D) program including diet, exercise and coping skills training, can decrease…
- Trial name
- CALM-D (NCT01739205)
- Testing
- CALM-D Intervention
- Volunteers
- 114 people
- Sponsor
- University of Miami
Substance Use, Delinquency
Family-based and Adolescent Residential Drug Treatment
The fundamental objective of this study is to compare the effectiveness of an intensive in-home family-based treatment, Multidimensional Family Therapy, with a multifaceted residential treatment, Adolescent Residential Treatment…
- Trial name
- ART (NCT01737632)
- Testing
- Multidimensional Family Therapy (MDFT), Adolescent Residential Treatment
- Where
- 2 sites in United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- University of Miami
Childhood Obesity
USDA Healthy Caregivers/Healthy Children: A Childhood Obesity Prevention Program
Background: Many unhealthy dietary and physical activity habits that foster the development of obesity are established by the age of five.
- Trial name
- HC2 (NCT01722032)
- Testing
- Childhood Obesity
- Volunteers
- 1,100 people
- Sponsor
- University of Miami
Kidney Transplantation, Kidney Disease
Using Donor Stem Cells and Alemtuzumab to Prevent Organ Rejection in Kidney Transplant Patients
Alemtuzumab is a man-made antibody used to treat certain blood disorders. This study will evaluate treatment of kidney transplant recipients with alemtuzumab and other immune system suppressing medications with or without…
- Conditions
- Kidney Transplantation, Kidney Disease, Kidney Failure
- Trial name
- NCT00183248
- Testing
- Alemtuzumab, Mycophenolate mofetil, Sirolimus
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Miami
Breast Cancer
Dose Dense Carboplatin, Taxotere and Herceptin As Primary Systemic Therapy in Breast Cancer
Dose dense therapy has been shown to increase survival in the adjuvant setting of breast cancer. It is unknown if dose dense therapy will improve survival in tumors that express her-2.
- Trial name
- NCT00232479
- Testing
- trastuzumab, docetaxel and carboplatin in dose dense regimen
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Miami
Substance Use, Delinquency
Family-Based Juvenile Drug Court Services
The objective of the proposed study is to adapt and implement an efficacious adolescent substance abuse treatment, Multidimensional Family Therapy (MDFT), within the juvenile drug court service system.
- Trial name
- JDC (NCT01668303)
- Testing
- Miami Juvenile Drug Court-MDFT, Miami Juvenile Drug Court -TAU
- Where
- 4 sites in United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of Miami
Neovascular Age-related Macular Degeneration
An OCT-Guided Variable Dosing Regimen With Ranibizumab for the Treatment of Neovascular AMD
This study was designed to evaluate a variable dosing regimen with intravitreal ranibizumab for the treatment of patients with neovascular age-related macular degeneration (AMD) in the Prospective OCT Imaging of Patients with…
- Trial name
- NCT00373659
- Testing
- Ranibizumab (Lucentis)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Miami
Acute Lymphoblastic Leukemia, Central Nervous System Tumors
Assessing the Effectiveness of Individual Education Plans for Childhood Cancer Survivors
Neurodevelopmental outcomes in children treated for cancer involving the central nervous system (CNS) provide educators with new challenges with regards to classification, monitoring, and intervention in the regular or special…
- Conditions
- Acute Lymphoblastic Leukemia, Central Nervous System Tumors, Lymphoma
- Trial name
- NCT00945828
- Testing
- Annual Intervention Group, Quarterly Monitoring of IEP
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of Miami
Breast Cancer
Facilitating Positive Adaptation to Breast Cancer
The purpose of this study is to test the effects of a 10-wk cognitive behavioral stress management (CBSM) intervention vs. a single-day psycho-educational seminar on psychosocial adaptation and physiological adaptation in women…
- Trial name
- NCT01422551
- Testing
- Cognitive Behavioral Stress Management, a psycho-educational control
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- University of Miami
Melasma
Oral Polypodium Leucotomos for Melasma
Primary Objective: To determine whether there is improvement in the melasma of participants taking oral Polypodium Leucotomos Secondary Objective: To determine whether oral Polypodium Leucotomos is well tolerated in study…
- Trial name
- NCT01162850
- Testing
- Polypodium Leucotomos
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Miami
Liver Transplantation, Resistance Training
Study of Resistance Strengthening Versus Ambulation Post-Liver Transplant
Resistance strengthening exercise will increase strength and functional activity greater than ambulation in subjects post-liver transplantation.
- Conditions
- Liver Transplantation, Resistance Training, Activities of Daily Living
- Trial name
- NCT01216722
- Testing
- Resistance Strengthening Exercise Program
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Miami
Spinal Cord Injury
Comparison of Post-pinal Cord Injury (SCI) Locomotor Training Techniques
Background: Body weight supported (BWS) locomotor training improves overground walking ability in individuals with motor-incomplete spinal cord injury (SCI).
- Trial name
- NCT01095380
- Testing
- Locomotor training
- Volunteers
- 74 people
- Sponsor
- University of Miami
End-Stage Renal Disease, Living Donors
Thymoglobulin Versus Alemtuzumab Versus Daclizumab in Living Donor Renal Transplantation
The purpose of this study is to observe in a randomized prospective study the effectiveness and toxicity of Thymoglobulin vs. Campath-1H used for induction therapy in recipients of living donor (LD) kidneys, compared with the…
- Trial name
- NCT01046955
- Testing
- Anti-Thymocyte Globulin vs Campath-1H vs Daclizumab
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Miami
Acne Vulgaris
5% Sodium L-Ascorbyl-2-Phosphate Lotion for the Treatment of Acne Vulgaris
12-week study to compare the efficacy and safety of a course of a twice daily treatment with APS in the form of a lotion to its vehicle for the treatment of acne.
- Trial name
- NCT00714454
- Testing
- APS Topical Lotion
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
Breast Cancer
The Magnetic Resonance Imaging Evaluation of Doxorubicin Cardiotoxicity
The purpose of this research study is to evaluate MR imaging in subjects receiving doxorubicin chemotherapy to see if MR can detect heart damage as well as or better than MUGA scans.
- Trial name
- NCT00530101
- Testing
- Doxorubicin
- Where
- 2 sites in United States
- Volunteers
- 3 people
- Sponsor
- University of Miami
HIV Infection, Opioid-Related Disorders
Buprenorphine HIV Care Integration Project
A007 is a randomized, two-arm study evaluating the effectiveness of standard drug addiction counseling with buprenorphine/naloxone to enhanced motivational drug counseling with buprenorphine/naloxone for the treatment for opioid…
- Trial name
- NCT00348868
- Testing
- enhanced behavioral motivation counseling, Motivational counseling, Standard counseling
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Miami
Bipolar Disorder
Family Workshops for Bipolar Disorder
This pilot study is looking at the effects of a brief psychoeducational workshop. These one day workshops are designed to increase family members knowledge about bipolar disorder and to help with processing emotions that go along…
- Trial name
- NCT00296283
- Testing
- integrative behavior couples therapy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Miami
Neovascular Age-Related Macular Degeneration
Prospective OCT Study With Lucentis for Neovascular AMD (PrONTO Study)
The PrONTO Study was designed to evaluate the response of neovascular age-related macular degeneration (AMD) patients to intravitreal Lucentis using Optical Coherence Tomography (OCT) imaging.
- Trial name
- NCT00344227
- Testing
- Lucentis (Ranibizumab)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Miami
HIV Infections, Leukoencephalopathy, Progressive Multifocal
A Pilot Study of the Efficacy of Recombinant Alpha Interferon (IFN-A2b) and Zidovudine (AZT) in the Treatment of Progressive Multifocal Leukoencephalopathy (PML) Complicating HIV-1 Infection
To study the effectiveness of alpha interferon (IFN-A2b) and zidovudine (AZT) in treating progressive multifocal leukoencephalopathy (PML) as a complication of HIV-1 infection.
- Trial name
- NCT00002270
- Testing
- Interferon alfa-2b, Zidovudine
- Where
- United States
- Sponsor
- University of Miami