Clinical trials: sponsored by University of Miami
Exercise
High-Intensity Functional Training (HIFT) vs Moderate-Intensity Continuous Training (MICT) in College Students
The purpose of this study is to compare two types of exercise programs in college students: high-intensity functional training and moderate-intensity continuous training.
- Trial name
- NCT07745270
- Testing
- High-Intensity Functional Training (HIFT), Moderate-Intensity Continuous Training (MICT)
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Miami
Substance Abuse, Domestic Violence
Hispanic Men Building Respect Education and Safety/ HoMBRES Manteniendo Respeto, Educacion y Seguridad.
The overall objective of this project is to adapt and enhance HoMBReS (Hispanic Men Building Respect, Education, and Safety within Families /Hombres Manteniendo Respeto, Educacion y Seguridad de Familia), a Center for Disease…
- Conditions
- Substance Abuse, Domestic Violence, HIV/AIDS
- Trial name
- HoMBRES (NCT03730987)
- Testing
- HoMBReS intervention, Families Talking Together (FTT), Diabetes Prevention Intervention
- Where
- United States
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- University of Miami
Pulmonary Disease, Chronic Obstructive, Hypoxia
Hypoxia and Heart Rate Variability
The purpose of this study is to evaluate how variations in oxygen demands may change heart electrical activity in individuals with and without oxygen dependence.
- Trial name
- NCT05606406
- Testing
- Nocturnal Oxygen
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
Breast Cancer, Early-stage Breast Cancer
SABER Study for Selected Early Stage Breast Cancer
The purpose of this study is to find the most effective dose of radiation therapy to give to breast tumors in a shorter period of time, prior to standard partial mastectomy/axillary surgery.
- Trial name
- SABER (NCT04360330)
- Testing
- Stereotactic Ablative Breast Radiotherapy
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Miami
Peyronie Disease, Sexual Dysfunction, Physiological
PRP for Treatment of Peyronie's Disease
The purpose of this study is to learn about the effects of Platelet-Rich Plasma (PRP) injection in men with Peyronie's Disease (PyD).
- Conditions
- Peyronie Disease, Sexual Dysfunction, Physiological, Sexual Dysfunction Male, Genital Diseases, Male
- Trial name
- NCT04512287
- Testing
- Autologous Platelet-Rich Plasma (PRP)
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of Miami
Human Immunodeficiency Virus, Cardiometabolic Risk
The Happy Older Latinos Are Active (HOLA) Health Promotion Study in HIV-Infected Latino Men
The purpose of this study is to examine the feasibility of an intervention to prevent chronic diseases like diabetes, high blood pressure, and obesity in midlife and older Latino adults living with HIV.
- Trial name
- HOLAHIV (NCT03839212)
- Testing
- HOLA Component 1, HOLA Component 2, HOLA Component 3
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Miami
Recurrent Glioblastoma
Spectroscopic MRI, Proton Therapy, and Avastin for Recurrent Glioblastoma
The purpose of this research is to find hidden cancer with an experimental magnetic resonance imaging (MRI) scan called spectroscopic magnetic resonance imaging (sMRI).
- Trial name
- NCT05284643
- Testing
- Intensity Modulated Proton Therapy (IMPT), Bevacizumab
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- University of Miami
Hidradenitis Suppurativa
Aviclear for Hidradenitis Suppurativa (HS)
The objective is to evaluate the safety and efficacy of the Cutera 1726 nm laser system (also referred to as AviClear) for the treatment of HS.
- Trial name
- NCT06801795
- Testing
- AviClear
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Miami
Rosacea, Papulopustular, Rosacea, Erythematotelangiectatic
Rosacea Radiofrequency Microneedling
There are 3 main objectives of this proposal as follows: (1) to assess the efficacy of radiofrequency microneedling in the treatment of erythematotelangiectatic and or papulopustular rosacea, (2) to determine the potential for…
- Trial name
- NCT06801717
- Testing
- KTP Laser Therapy, Radiofrequency microneedling
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Miami
Frontal Fibrosing Alopecia
Facial Papules in Frontal Fibrosing Alopecia (FFA)
The objective is to evaluate the safety and efficacy of the Cutera 1726 nm laser system (also referred to as AviClear) for the treatment of facial papules in frontal fibrosing alopecia (FFA).
- Trial name
- NCT07340671
- Testing
- Cutera® 1726 nm laser system
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Miami
Mild Traumatic Brain Injury
Disparity Driven Vergence in Mild Traumatic Brain Injury (mTBI)
This study aims to determine the validity and safety of disparity driven vergence using a portable goggle system (I-PAS) using a pseudorandom ternary sequence of frequencies for testing.
- Trial name
- NCT03529799
- Testing
- I-PAS Goggles
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Miami
Dry Eye, Eye Diseases
Autologous Serum Tears With Hyaluronate vs Balanced Salt Solution for Moderate-to-Severe Dry Eye
This study aims to find out whether adding sodium hyaluronate, a moisturizing ingredient commonly found in artificial tears, makes autologous serum eye drops more effective for treating moderate-to-severe dry eye disease.
- Conditions
- Dry Eye, Eye Diseases, Eyes Dry Chronic
- Trial name
- NCT07413172
- Testing
- Autologous Serum Tears (50% Autologous Serum Tears + 0.2% Sodium Hyaluronate), Biological - Autologous Serum Tears (50% Autologous Serum Tears + Balanced Saline Solution (BSS), Standard of Care (SOC) Treatment
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Miami
Non Small Cell Lung Cancer
ctDNA to Predict Response to Chemo-Immunotherapy and Detect Minimal Residual Disease in Non-Small Cell Lung Cancer
The purpose of this study is to determine if a blood test called circulating tumor DNA (ctDNA) can be used to predict how well patients will respond to treatment and if there is any cancer left after surgery.
- Trial name
- DNA-PREDICT (NCT06902272)
- Testing
- Circulating Tumor Deoxyribonucleic acid (ctDNA) Assay, Pembrolizumab, Platinum Doublet Chemotherapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Miami
Acute Spinal Cord Injury
The Use of Functional Electrical Stimulation in Conjunction With Respiratory Muscle Training to Improve Unaided Cough in Individuals With Acute Spinal Cord Injury
The overall objective of this study is to improve unaided cough with abdominal and latissimus dorsi functional electrical stimulation in conjunction with respiratory muscle training in individuals with acute spinal cord injuries.
- Trial name
- AFES and RMT (NCT05745298)
- Testing
- Xcite Clinical Station
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Miami
Knee Osteoarthritis
Effectiveness and Safety of Embosphere Microspheres for Embolization of the Geniculate Artery for the Treatment of Pain With Known Moderate to Severe Knee Osteoarthritis
The purpose of this research study is to evaluate the effectiveness and safety of a permanent embolic (Embosphere Microspheres) for embolization of the geniculate artery for the treatment of moderate to severe knee osteoarthritis.
- Trial name
- NCT05112926
- Testing
- Embosphere Microspheres
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Miami
SCI - Spinal Cord Injury
Gut-Brain Neural Coupling in Spinal Cord Injury
The purpose of this research is to determine the effects of food on brain and stomach activity in persons with and without spinal cord injury (SCI).
- Trial name
- NCT07052344
- Testing
- Preload condition, Ad-libitum control condition
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Miami
Human Influenza
Tfh Dysfunction in HIV and Aging
The purpose of this research is to evaluate blood samples from HIV infected and non-HIV infected people to understand how aging and HIV infection affect the immune responses (body defenses against infection) to the flu vaccine.
- Trial name
- NCT04487041
- Testing
- Standard dose influenza vaccination, High dose influenza vaccination
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Miami
Endometrial Cancer
Fasting InTervention for Endometrial Cancer
The goal of this study is to find out if it is safe for women with endometrial cancer who are going to have surgery to fast (not eat) overnight.
- Trial name
- FIT-ENDO (NCT07622901)
- Testing
- Prolonged Overnight Fasting (POF), Blood Specimen Collection, Blood Sugar Monitor
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Miami
Prostate Cancer, Erectile Dysfunction Following Radical Prostatectomy
Human Amnion Membrane Allograft and Early Return of Erectile Function After Radical Prostatectomy
The purpose of this research study is to evaluate if placing a dehydrated human amnion chorion membrane (dHACM) over the nerves after removal of the prostate during surgery (radical prostatectomy) will allow an earlier recovery…
- Trial name
- HAMMER (NCT05842057)
- Testing
- BioDFence G3 Placental Tissue Membrane, Robot-Assisted Radical Prostatectomy
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- University of Miami
Seroma
Doxycycline Use in Post-Operative Seromas
Seromas are collections of serous fluid that can develop following surgical procedures and may persist as fibrous-lined pseudocysts if not adequately treated.
- Trial name
- NCT07498010
- Testing
- Doxycycline
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Miami