Clinical trials: sponsored by University of Miami
Unresectable Hepatocellular Carcinoma, Hepatocellular Carcinoma
Regorafenib and Yttrium-90 Radioembolization for Unresectable Hepatocellular Carcinoma
The purpose of this study is to determine the effects that Regorafenib in combination with Yttrium-90 (Y-90) radioembolization has on patients with unresectable hepatocellular carcinoma.
- Trial name
- NCT06902246
- Testing
- Regorafenib, TheraSphere™ Yttrium-90 Trans-Arterial Radioembolization
- Sponsor
- University of Miami
Amyotrophic Lateral Sclerosis, Frontotemporal Dementia
Phenotype, Genotype & Biomarkers in ALS and Related Disorders
The goals of this study are: (1) to better understand the relationship between the phenotype and genotype of amyotrophic lateral sclerosis (ALS) and related diseases, including primary lateral sclerosis (PLS), hereditary spastic…
- Conditions
- Amyotrophic Lateral Sclerosis, Frontotemporal Dementia, Primary Lateral Sclerosis, Hereditary Spastic Paraplegia
- Trial name
- NCT02327845
- Where
- 15 sites in United States, Germany and 1 more
- Volunteers
- 708 people, healthy volunteers welcome
- Sponsor
- University of Miami
Amyotrophic Lateral Sclerosis, Frontotemporal Dementia
TRIAL READY (Clinical Trial Readiness)
This study, being conducted under the auspice of the CReATe Consortium, will enroll patients with ALS and related disorders as well as healthy controls, with the goal of facilitating clinical validation of leading…
- Conditions
- Amyotrophic Lateral Sclerosis, Frontotemporal Dementia, ALS-Frontotemporal Dementia, Primary Lateral Sclerosis
- Trial name
- NCT03912987
- Where
- 3 sites in United States
- Volunteers
- 610 people, healthy volunteers welcome
- Sponsor
- University of Miami
Amyotrophic Lateral Sclerosis, ALS-Frontotemporal Dementia
Clinical Procedures to Support Research in ALS
The purpose of the Clinical Procedures To Support Research (CAPTURE) study is to utilize information collected in the medical record to learn more about a disease called amyotrophic lateral sclerosis (ALS) and related disorders.
- Conditions
- Amyotrophic Lateral Sclerosis, ALS-Frontotemporal Dementia, Primary Lateral Sclerosis, Progressive Muscular Atrophy
- Trial name
- CAPTURE-ALS (NCT03489278)
- Where
- 11 sites in United States
- Volunteers
- 1,200 people
- Sponsor
- University of Miami
Arthroplasty, Replacement, Knee, Osteoarthritis, Knee
TracPatch in Total Knee Arthroplasty
Total Knee Arthroplasty is becoming an increasingly common operation. An important part of a successful overall patient outcome is regaining functional range of motion after surgery.
- Trial name
- NCT03466476
- Testing
- Consensus TracPatch
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Miami
Knee Osteoarthritis, Arthritis Knee
Zynrelef Versus Adductor Canal Block
To compare postoperative MME consumption 72 hours after TKA in patients receiving intraoperative periarticular HTX-011 (Zynrelef) instillation versus adductor canal block.
- Trial name
- NCT07216586
- Testing
- ZYNRELEF 400Mg-12Mg Extended-Release Solution, Ultrasound-Guided Adductor Canal Block, Ropivacaine 0.5% Injectable Solution
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Miami
PSA, Elevated PSA
Marker Driven Selection of Patients for Prostate Biopsy and Management
The purpose of this research study is to determine if the interpretation of multiparametric MRI (mpMRI) with an algorithm called habitat risk score (HRS) in combination with a panel of blood and urine biomarkers is more effective…
- Conditions
- PSA, Elevated PSA, Prostate Cancer
- Trial name
- MDSelect (NCT04240327)
- Where
- United States
- Volunteers
- 289 people, healthy volunteers welcome
- Sponsor
- University of Miami
Pediatric Feeding Disorder, Chronic, Avoidant Restrictive Food Intake Disorder
The Use of Cyproheptadine in Pediatric Feeding Disorders
The goal of this clinical trial is to learn if Cyproheptadine, an appetite stimulant, can improve eating habits in children with Pediatric Feeding Disorders.
- Trial name
- NCT06751290
- Testing
- Cyproheptadine, Nutritional Counseling, Behavioral Counseling
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Miami
Peyronie Disease, Sexual Dysfunctions, Psychological
Safety and Efficacy of Collagenase Clostridium Histolyticum After Prior Intralesional PRP for Peyronie's Disease
The purpose of this study is to learn about the safety and side effects of intralesional collagenase clostridium histolyticum (CCH) injected into the Peyronies Disease (PD) plaque after receiving prior treatment with…
- Conditions
- Peyronie Disease, Sexual Dysfunctions, Psychological, Genital Diseases, Male
- Trial name
- NCT05777031
- Testing
- Collagenase Clostridium Histolyticum (CCH)
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- University of Miami
Blood Pressure, Relaxation
Consciousness Studies and Cardiovascular Health
The objective of the study is to evaluate whether a virtual reality (VR) based intervention combining binaural beats, photic stimulation, and real-time biofeedback reduces stress and improves physiological markers compared to…
- Conditions
- Blood Pressure, Relaxation, Virtual Reality
- Trial name
- NCT07620639
- Testing
- Virtual Reality Relaxation, Video Meditation, Live Guided
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Miami
Infant Development
Baby Item Learning and Development Study
The goal of this study is to experimentally test whether baby items can promote healthy infant development.
- Trial name
- NCT04267302
- Testing
- Baby Bouncer, Infant t-shirts with Language Environment Analysis (LENA) audio recorders, Baby Carrier
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Miami
Diabetes Mellitus, Type 1
Type 1 Diabetes Recurrence in Pancreas Transplants
The hypothesis is that humoral and cellular islet-specific responses are an early risk factor for recurrence of autoimmunity and hyperglycemia in simultaneous pancreas-kidney (SPK) recipients independent of alloimmunity.
- Trial name
- NCT01047865
- Where
- United States
- Volunteers
- 238 people
- Sponsor
- University of Miami
Spinal Cord Injuries
Auricular Vagus Nerve Stimulation (aVNS) in Chronic Spinal Cord Injuries (SCI)
The purpose of this research is to test if Auricular Vagal Nerve Stimulation (aVNS) is safe in persons with spinal cord injury (SCI).
- Trial name
- NCT06588608
- Testing
- auricular nerve stimulation (aVNS)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Miami
Healthy
How Does the Type of Waveform Affect Tolerability With Transcutaneous Auricular Vagus Nerve Stimulation?
The purpose of this research study is to investigate the effects of different forms of a gentle form of electrical stimulation applied to the ear, known as transcutaneous auricular vagus nerve stimulation (taVNS).
- Trial name
- NCT06614933
- Testing
- Biphasic transcutaneous auricular vagus nerve stimulation, Monophasic transcutaneous auricular vagus nerve stimulation
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Miami
Monochorionic Diamniotic Placenta, Monochorial Monoamniotic Placenta
Database of Monochorionic Pregnancies
The purpose of this study is to collect and analyze data regarding natural history, indications for fetal interventions, and maternal and fetal/neonatal outcomes associated with complicated monochorionic twin pregnancy.
- Conditions
- Monochorionic Diamniotic Placenta, Monochorial Monoamniotic Placenta, Twin; Complicating Pregnancy, Twin to Twin Transfusion Syndrome
- Trial name
- NCT05543499
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- University of Miami
Erectile Dysfunction
Shockwave Therapy and Platelet Rich Plasma for the Treatment of Erectile Dysfunction
The purpose of this research study is to evaluate whether the combination of Shock Wave Therapy (SWT) with Platelet Rich Plasma (PRP) is synergistic and can reverse the pathology of microvascular Erectile Dysfunction (ED) and…
- Trial name
- COCKTAIL (NCT05048667)
- Testing
- Shock Wave therapy (SWT), Platelet Rich Plasma (PRP)
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- University of Miami
Mental Health Wellness 1
Jump Start Plus COVID-19 Support
The purpose of the study is to further develop and examine the Jump Start Plus COVID Support (JS+CS) program, which encourages improved psychosocial functioning by promoting resiliency in childcare centers.
- Trial name
- NCT05445518
- Testing
- Jump Start Plus COVID Support, Healthy Caregivers-Healthy Children (HC2)
- Where
- United States
- Volunteers
- 1,505 people, healthy volunteers welcome
- Sponsor
- University of Miami
Stress, Hypertension
Virtual Reality Intervention for Stress, Resilience, and Blood Pressure Management in Black Women - Realist Women Study
The Realist Women Study wants to see if a special program using virtual reality can help Black women deal with stress and improve Black women's heart health.
- Trial name
- NCT06544902
- Testing
- VR Stress Management, Education Control
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Miami
Accommodation, Daily Activities
Project Independence
This project aims to develop and test the feasibility, acceptability, and preliminary impact of a brief, online single-session intervention (SSI) for caregivers of autistic youth ages 10 to 14.
- Conditions
- Accommodation, Daily Activities, Independence, Autism
- Trial name
- NCT07572110
- Testing
- Project Independence
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Miami
Burnout
Mindfulness Training for First Responders
The present study evaluates the efficacy of Mindfulness-Based Attention Training on measures targeting cognitive abilities and emotional well-being in first responders.
- Trial name
- NCT06582927
- Testing
- Mindfulness-Based Attention Training (MBAT)
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Miami