Clinical trials: sponsored by University of Minnesota
Depression, Depressive Disorder
Mindful Breathing and tDCS for Depression
This study will investigate whether transcranial direct current stimulation (tDCS) targeting the dorsolateral prefrontal cortex (DLPFC) can enhance the therapeutic effect of mindful breathing training (MBT) for adolescent…
- Trial name
- NCT03897699
- Testing
- Transcranial Direct Current Stimulation, Mindful Breathing
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of Minnesota
Shoulder Injuries, Shoulder Pain
Mitigating the Impact of Shoulder Movement Dysfunction; a Randomized Controlled Trial
The purpose of the proposed work is to screen the effectiveness of an evidence-based, targeted, treatment intervention versus a non-specific, generalized, treatment intervention to treat symptomatic shoulder instability in…
- Trial name
- NCT04852640
- Testing
- Active Rehabilitation Program (ARP), Nonspecific Passive Intervention (NPI)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Minnesota
Raynaud Disease, Raynaud Phenomenon
Phototherapy For Treatment Of Raynaud's Phenomenon
To determine if blue light therapy can improve the symptoms of Raynaud's phenomenon, and provide parameters for ultimately designing commercial treatment devices, an investigational stationary phototherapy unit was designed and…
- Conditions
- Raynaud Disease, Raynaud Phenomenon, Raynaud Syndrome
- Trial name
- NCT04898036
- Testing
- Blue Light Therapy
- Where
- United States
- Sponsor
- University of Minnesota
Coronavirus Infection, COVID
Assessment of Exam Findings in Coronavirus Disease 2019 (COVID-19) With Point-of-Care Ultrasonography (POCUS)
Specific Aims: 1. The investigators will prospectively evaluate and analyze changes in the appearance of the lungs and heart through serial acquisition of focused point-of-care ultrasound images in a cohort of patients with or…
- Conditions
- Coronavirus Infection, COVID, Covid-19, SARS-CoV-2
- Trial name
- NCT04339998
- Testing
- Point-of-Care Ultrasonography (POCUS)
- Where
- 2 sites in United States
- Volunteers
- 129 people
- Sponsor
- University of Minnesota
Cancer
Implementing Personalized Exercise Prescriptions Through Mobile Health in the Elderly Cancer Survivors
Cancer remains a vital public health concern in the U.S. Research evidence has shown that physical activity provides many physical and mental health benefits after cancer diagnosis and plays an important role in reducing…
- Trial name
- NCT05069519
- Testing
- Personalized Smartwatch, Facebook Health Education
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- University of Minnesota
Smokeless Tobacco Use, Tobacco Dependence
Novel Determinants and Measures of Smokeless Tobacco Use: Study 1
The extent of toxicity varies considerably across different brands of smokeless tobacco (ST) products and data suggest that greater toxicity may result in greater health risks.
- Trial name
- NCT01067586
- Where
- 3 sites in United States
- Volunteers
- 359 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Anesthesia, Surgery
Comparison of Ambu Auragain and I-Gel Supraglottic Airways in Adult Patients at an Ambulatory Surgery Center
The purpose of this study is to determine if an I-gel laryngeal mask airway (LMA) has a higher oropharyngeal leak pressure compared to an Ambu Auragain in adult patients in an ambulatory surgery center.
- Trial name
- NCT04286581
- Testing
- I-Gel Laryngeal Mask Airway, Ambu Auragain Laryngeal Mask Airway
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- University of Minnesota
Sarcoma
PET CT as Predictor of Response in Preoperative Chemotherapy for Soft Tissue Sarcoma
RATIONALE: Diagnostic procedures, such as positron emission tomography (PET) scan and computated tomography (CT) scan, may help doctors predict a patient's response to treatment and may help plan the best treatment.
- Trial name
- NCT00346125
- Testing
- pegfilgrastim, doxorubicin hydrochloride, ifosfamide
- Where
- 2 sites in United States
- Volunteers
- 70 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Parenting
SMART Optimization of a Parenting Program for Active-duty Families
The overarching goal of the "SMART Optimization of a Parenting Program for Active-Duty Families" study is to advance the "development, adaptation, efficiency or optimization, and testing of a prevention intervention by using a…
- Trial name
- SMART (NCT05509348)
- Testing
- Phase 1: ADAPT Workshop, Phase 1: ADAPT Online, Phase 2: ADAPT Group
- Where
- 4 sites in United States
- Volunteers
- 423 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Anorexia, Anorexia Nervosa
Comparing Real-time fMRI Neurofeedback Versus Sham for Altering Limbic and Eating Disturbances in Anorexia Nervosa
The goal of the purposed research is to extend prior work (STUDY00003758: Real-time fMRI Neurofeedback to Alter Limbic Disturbances in Anorexia Nervosa) on real-time fMRI (rt-fMRI) neurofeedback (focused on amygdala…
- Trial name
- NCT04220112
- Testing
- Real-Time Functional Magnetic Resonance Imaging (RT-fMRI)
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Minnesota
Phrenic Nerve Paralysis
Evaluation of Diaphragm Movement After an Interscalene Block
The purpose of this study is to evaluate the movement of the diaphragm after an interscalene block with liposome bupivacaine (LB) compared to interscalene block (IB) with bupivacaine.
- Trial name
- NCT03636542
- Testing
- liposomal bupivacaine, bupivacaine
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Minnesota
Smoking, Cigarette Smoking
e-Cigarette - DNA Adducts
This study will examine the level of toxicity of e-cigarette use compared to smokers and nonsmokers including inflammation markers, toxicant and carcinogen exposure.
- Conditions
- Smoking, Cigarette Smoking, Electronic Cigarettes
- Trial name
- NCT03284632
- Where
- United States
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Multiple Myeloma, Non-Hodgkin Lymphoma
Ph I Trial of NAM NK Cells and IL-2 for Adult Pts With MM and NHL
This is a phase I trial with pilot expansion of HLA-haploidentical or HLA-mismatched related donor nicotinamide expanded-natural killer (NAM-NK) cell based therapy for patients with relapsed or refractory multiple myeloma (MM) or…
- Conditions
- Multiple Myeloma, Non-Hodgkin Lymphoma, Diffuse Large B Cell Lymphoma, Mantle-Cell Lymphoma
- Trial name
- NCT03019666
- Testing
- Nicotinamide Expanded Haploidentical or Mismatched Related Donor Natural Killer Cells
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Masonic Cancer Center, University of Minnesota
Fetal Alcohol Spectrum Disorders
Choline Supplementation as a Neurodevelopmental Intervention in Fetal Alcohol Spectrum Disorders
This is a randomized, double-blind, placebo-controlled trial of choline supplementation in children with Fetal Alcohol Spectrum Disorders (FASD). The primary outcome measures are cognitive measures.
- Trial name
- NCT02735473
- Testing
- Choline bitartrate
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Minnesota
COVID, COVID-19
Detecting SARS-CoV-2 in Tears
Purpose: To determine the presence of SARS-CoV-2 in tears To determine SARS-CoV-2 receptors in tear production system
- Conditions
- COVID, COVID-19, Corona Virus Infection, SARS-CoV-2
- Trial name
- NCT04526769
- Testing
- Tear Collection
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Minnesota
Autism Spectrum Disorder
Mentorship Program for Individuals With Autism Spectrum Disorder (ASD)
The purpose of this pilot project is to evaluate the feasibility of a mentorship program for adolescents with autism spectrum disorder (ASD). Data will be collected from adolescents with ASD and their parents/guardians.
- Trial name
- NCT05300295
- Testing
- Mentoring Program
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Minnesota
Healthy
Safety and Feasibility of Imaging at 10.5 Tesla
This unique NMR instrument is the first of its kind, and the most advanced system that is capable of brain, torso and extremity imaging in humans at such a high magnetic field.
- Trial name
- NCT03346707
- Testing
- 10.5 Tesla
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Cardiotoxicity
Cardiac Fibrosis and Risk Prediction in Cancer Treatment-Related Cardiotoxicity
The purpose of this study is to determine whether pre-existing cardiac fibrosis is a predictor of cancer treatment-related cardiotoxicity.
- Trial name
- NCT02798679
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Minnesota
Aphasia
Transcranial Direct Stimulation (tDCS) and Behavioral Intervention in Aphasia
We hypothesize patients who have difficulty with word recall (naming pictures) due to a stroke will experience greater benefit in word recall after receiving a combination of transcranial direct current stimulation (tDCS) and…
- Trial name
- NCT02226796
- Testing
- Transcranial direct current stimulation
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Minnesota
Psychosis, Schizophrenia
Exercise Target Brain Oscillations in Psychosis
Previous studies have shown that cardiorespiratory fitness (how well the heart and lungs are able to function during physical activity) is often reduced in people with psychosis.
- Conditions
- Psychosis, Schizophrenia, Schizoaffective Disorder
- Trial name
- NCT05338424
- Testing
- Sprint Interval Training (SIT)
- Where
- United States
- Sponsor
- University of Minnesota
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.