Clinical trials: sponsored by University of Minnesota
Cardiovascular Diseases
Home-Based High Intensity Interval Training Intervention for Low Active Adults
The purpose of this study is to examine the effect of a home-based high intensity interval training intervention on exercise among low active adults (defined as engaging in exercise 90 minutes or less per week).
- Trial name
- NCT03479177
- Testing
- High Intensity Interval Training
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Diet Modification
Gum Acacia and Blood Glucose
This study will provide needed insight on the satiety and blood glucose and l effects of the soluble fiber gum acacia at 20g and 40g doses.
- Trial name
- NCT03716479
- Testing
- Low Fiber, High Fiber
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Diet Modification
Sunfiber and the Microbiota
The aim of this study is to look at the effect Sunfiber has on the gut microbiota.
- Trial name
- NCT03722862
- Testing
- Low fiber, High fiber
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Breast Cancer
Quantitative Methods for Supplementing Contrast-Enhanced Magnetic Resonance Imaging of Breast Cancer
Contrast-enhanced magnetic resonance imaging (CE-MRI) is now established as the most accurate non-invasive imaging modality for characterizing breast cancer.
- Trial name
- NCT02058758
- Testing
- Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Milk Expression, Breast
Exparel PK and Breast Milk Excretion
Investigate the pharmacokinetics of Liposomal Bupivacaine and its excretion in breast milk in patients undergoing TAP block after their scheduled C -section delivery
- Trial name
- NCT03526419
- Testing
- Bupivacaine liposome
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Childhood Obesity
CHAT at HOME Pilot Study
This study is evaluating the acceptability and feasibility of a 10 session parent-targeted phone-based childhood obesity treatment (n=40).
- Trial name
- NCT03661918
- Testing
- In-Person First Session, Second Caregiver, WiFi-enabled Scale
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Cocaine Dependence, Nicotine Dependence
Progesterone and Atomoxetine for Cocaine Cessation
The purpose of this study is to examine the role of progesterone (a hormone found in both men and women) on stopping cocaine use.
- Trial name
- NCT01741376
- Testing
- Progesterone
- Where
- United States
- Sponsor
- University of Minnesota
Mucopolysaccharidosis Type I, Mucopolysaccharidosis Type II
Longitudinal Studies of Brain Structure and Function in MPS Disorders
Neurobehavioral function and quality of life are compromised in many patients with mucopolysaccharidosis (MPS) disorders. The long-term goals of this research are to: 1) more accurately inform patients/parents regarding potential…
- Conditions
- Mucopolysaccharidosis Type I, Mucopolysaccharidosis Type II, Mucopolysaccharidosis Type VI, Mucopolysaccharidosis Type IV
- Trial name
- NCT01870375
- Where
- 4 sites in United States, Canada
- Volunteers
- 100 people
- Sponsor
- University of Minnesota
Stroke
Forearm Rotation Orthosis for Stroke
The purpose of this study is to examine the efficacy of a forearm rotation orthosis combined with the occupational therapy task-oriented approach on functional performance for persons with a hemiparetic arm.
- Trial name
- NCT01987414
- Testing
- occupational therapy task-oriented approach, Forearm rotation orthosis, No treatment
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Minnesota
Environmental Exposure
Pilot Study to Assess the Quantitative Dermal Transfer Efficiencies of Solids for Multiple Transfer Pathways
Dermal transfer efficiency has been defined as the amount of material that moves from one surface to another following contact. The investigators propose to measure dermal transfer efficiency for the following pathways: (1)…
- Trial name
- NCT02529748
- Testing
- Participants for Surface Skin Sampling, Elemental metallic lead, Tinopal
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Peripheral Artery Disease
Ankle-foot Orthoses for Peripheral Artery Disease
The primary aim of this study is to investigate the effect of an ankle foot orthoses (AFO) on the primary outcome of peak walking time (PWT) in patients with peripheral artery disease (PAD).
- Trial name
- NCT02280200
- Testing
- AFO to improve outcomes
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Minnesota
Kleptomania
Double-Blind Naltrexone in Kleptomania
The goal of the proposed study is to evaluate the efficacy and safety of naltrexone in kleptomania.
- Trial name
- NCT00332579
- Testing
- Naltrexone
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Minnesota
Compulsive Buying
Memantine Treatment of Compulsive Buying
This is an 8-week, open-labe study of memantine in the treatment of compulsive buying.
- Trial name
- NCT00830375
- Testing
- Memantine
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- University of Minnesota
Stress Urinary Incontinence
A Study of Transcorporal Versus Standard Artificial Urinary Sphincter Placement
We propose a randomized non-blinded comparison of standard vs. transcorporal approach for placement of an artificial urinary sphincter in male patients with stress urinary incontinence after radiation and radical prostatectomy…
- Trial name
- NCT02524366
- Testing
- Artificial Urinary Sphincter
- Where
- United States
- Sponsor
- University of Minnesota
Epilepsy, Migraines
Pharmacokinetics and Safety of Intravenous Topiramate in Adult Patients
The aims of this study are to determine, in adult patients on maintenance topiramate therapy, the steady-state pharmacokinetics and safety of orally and intravenously administered topiramate.
- Trial name
- NCT00753493
- Testing
- intravenous topiramate
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Minnesota
Healthy
Effects of Genotype on CYP2C9 Drug Interactions
This research study will help determine how a person's genetic makeup affects their responses to drugs, the ability of the body to break down drugs, and their potential to experience an interaction between drugs.
- Trial name
- NCT01061112
- Testing
- Flurbiprofen Control - Flurbiprofen Only, Flurbiprofen Inhibition - Flurbiprofen & Fluconazole, Ketoprofen Control - Ketoprofen Only
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Congenital Hemiparesis
Comparing the Location of the Motor Cortex in Children Using Two Methods
Hypothesis: In typically developing children (TDC), use of conventional EEG landmarks to determine the brain area that controls hand function will not differ from TMS-guided determination of individual motor hotspots.
- Trial name
- NCT02015338
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Myometrium; Contractility, GDM
Adipokines Effect in Myometrial Contractility
Investigate the effect of two adipokines which are adiponectin and TNFa on the force of myometrial contractility in diabetic, non-obese pregnant women and obese, non-diabetic term pregnant women at the time of scheduled cesarean…
- Conditions
- Myometrium; Contractility, GDM, Obesity
- Trial name
- NCT03505541
- Testing
- Adiponectin and TNFa
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Aortic Aneurysm, Thoracic, Aortic Aneurysm, Abdominal
Development of Ultra-Low Dose CT Based Screening for Aortic Aneurysms
The primary objective of this research project is development and validation of a new, non-contrast gated aortic (NCGA) computer tomography scan algorithm for screening of aortic aneurysm in the chest and abdomen in at risk…
- Trial name
- NCT03479164
- Testing
- Ultra Low-Dose CT
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Minnesota
Cocaine Dependence
Pilot Study of Lisdexamfetamine for Treatment of Cocaine Dependence
The purpose of this study is to evaluate ideal dose or lisdexamfetamine and tolerability, plus reduction in cocaine use and craving.
- Trial name
- NCT01490216
- Testing
- lisdexamfetamine
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of Minnesota