Clinical trials: sponsored by University of Minnesota
Oral Cancer
Assessment of Mandibular Bone Invasion With MRI Using SWIFT
The primary objective of this study is to improve the diagnostic accuracy and specificity of MRI in detecting the degree of bone involvement and invasion in oral cancer.
- Trial name
- NCT01817140
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Minnesota
Adolescent Immunization
Improving Adolescent Vaccination in Appalachian Kentucky
The proposed project develops a community and school-based intervention to enhance understanding of the importance all age-appropriate vaccinations, and uses an innovative, comprehensive approach (Project INSPIRE - Instilling…
- Trial name
- INSPIRE (NCT01838161)
- Testing
- Part II, Part III, Part I
- Where
- 2 sites in United States
- Volunteers
- 597 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Hypercholesterolemia
Effects of Black Tea Intake on Serum Lipids
A diet-controlled clinical trial which attempts to provide estimates of the effect of black tea consumption on serum lipids under tightly controlled conditions, including a controlled diet.
- Trial name
- NCT01882283
- Testing
- Tea Treatment Group
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Safety and Pharmacokinetics of Intravenous Baclofen
Dose Escalation Study of Intravenous Baclofen in Healthy Adult Volunteers
The objective of this study is to determine safety and characterize pharmacokinetics of higher doses of intravenous baclofen in healthy subjects.
- Trial name
- NCT01931319
- Testing
- Intravenous baclofen
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Knee Osteoarthritis
Yoga Versus Exercises for Managing OA
The purpose of the study is to examine the short and long term effects of Hatha yoga compared to the current recommended exercise program in promoting physical function, alleviating osteoarthritis (OA)-related symptoms, fear of…
- Trial name
- YEMO (NCT02525341)
- Testing
- Hatha yoga, Aerobic and strengthening exercises, General education
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- University of Minnesota
Toileting Disability, Functional Urinary Incontinence
Defeating Urinary Incontinence With Exercise Training (DUET) Feasibility Study
Pilot study to determine the feasibility and possible treatment effect of a multi-component intervention combining non-drug treatments for urinary incontinence and physical activity to improve urinary incontinence, toileting…
- Trial name
- DUET (NCT02206958)
- Testing
- Defeating Urinary Incontinence with Exercise Training
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Minnesota
Oxidative Stress, Alzheimer's Disease
Human Brain Antioxidants During Oxidative Stress
Antioxidants are important for having a good memory and for smart thinking when people get old, and that is important for everyone's quality of life.
- Conditions
- Oxidative Stress, Alzheimer's Disease, Aging
- Trial name
- NCT01713816
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Toothache, Temporomandibular Joint Disorders
Multimodal Assessment of Sensory Processing and Brain Features in Patients With Chronic Orofacial Pain
This proposal will investigate pain modulatory mechanisms and brain functional and structural characteristics using multiple MRI modalities in persistent dentoalveolar pain disorder (PDAP) patients with and without…
- Trial name
- NCT02630771
- Testing
- Pressure pain threshold
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Deliberate Self Harm
Early Study of N-Acetylcysteine to Treat Deliberate Self-Harm in Adolescents
Deliberate Self-Harm (DSH) among adolescents is a serious behavioral problem associated with significant injury, impaired functioning, reduced quality of life, and high rates of psychiatric hospitalizations.
- Trial name
- NCT01111734
- Testing
- N-Acetylcysteine, fMRI
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Tinnitus
Acoustic Stimulation Paired With Body and Cortical Stimulation for Modulating Tinnitus
The purpose of the study is to investigate different stimulation parameters for a new noninvasive approach for modulating the brain that could potentially be beneficial for decreasing tinnitus perception.
- Trial name
- NCT02283216
- Testing
- noise sound stimulation (Tucker-Davis Technologies), body electrical stimulation (Digitimer device), transcranial magnetic stimulation (Magstim)
- Where
- United States
- Sponsor
- University of Minnesota
Arthroplasty, Replacement
Comparison of Comparison of Ropivacaine and Liposomal Bupivacaine for Total Knee Arthroplasty
This is a randomized prospective outcomes study comparing two groups of patients. One group will receive liposomal bupivacaine for a periarticular injection.
- Conditions
- Arthroplasty, Replacement, Knee
- Trial name
- NCT02616367
- Testing
- liposomal bupivacaine Periarticular injection, Ropivacaine Periarticular Injection
- Sponsor
- University of Minnesota
Type 2 Diabetes
Mitigation of Type 2 Diabetes by Partial Ileal Bypass
This is a study of people with type 2 diabetes and high cholesterol between age 18 and 65. This study is trying to figure out if a partial bypass of the small intestine can reverse type 2 diabetes for people who require…
- Trial name
- NCT02493374
- Where
- United States
- Sponsor
- University of Minnesota
Rotator Cuff Shoulder Syndrome and Allied Disorders
Shoulder Motion Guided Patient Diagnostic and Treatment Classification
The investigators purpose is to determine the ability of a low cost, currently available imaging technique to predict shoulder movement disorders and the location of shoulder disease based on motion analysis of subjects with…
- Trial name
- NCT02104531
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Thoracic Diseases, Parathyroid Diseases
Interference of Biotin Supplementation in Biotin-streptavidin Platforms for Hormone Testing
The B vitamin biotin is widely available as an over the counter supplement, often advertised and used to promote health of hair, skin and nails.
- Trial name
- NCT03034707
- Testing
- biotin
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Parkinson Disease, Gaucher Disease
Detecting Dopaminergic Deficits in Individuals At-risk for Parkinsonism
The purpose of this study is to determine if participants have changes in dopamine cells in their brain using DaTSCAN™ brain imaging.
- Conditions
- Parkinson Disease, Gaucher Disease, Idiopathic Rapid Eye Movement Sleep Disorder
- Trial name
- NCT01358474
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Hypertension Uncomplicated, Pre Hypertension
A Biomarker to Detect Salt Sensitivity
The investigators are proposing that individuals with elevated levels of NT-proBNP are resistant to natriuretic peptides and are unable to handle sodium loads and maintain optimal blood pressure values.The investigators will test…
- Trial name
- NCT03147170
- Testing
- High and low salt diets
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Minnesota
Carpal Tunnel Syndrome
Botulinum Toxin for Carpal Tunnel Syndrome
To compare local steroid injections to local Botulinum toxin A injection in a double-blinded study.
- Trial name
- NCT00701233
- Testing
- Botulinum toxin, Corticosteroid injection into Carpal Tunnel
- Where
- United States
- Sponsor
- University of Minnesota
Melanoma (Skin)
Pilot Study of Intervention to Reduce Sunburns in Melanoma Survivors
This project will pilot test whether a wearable device that tracks sun exposure and provides alerts regarding sun exposure and protection behaviors will reduce sunburns in melanoma survivors.
- Trial name
- NCT03518229
- Testing
- Microsoft Band 2 + UV messaging, Microsoft Band 2
- Sponsor
- University of Minnesota
Healthy
The Effects of Single-Pulse Transcranial Magnetic Stimulation on the Autonomic Nervous System in Healthy Adults
The purpose of this study is to determine the effects of TMS on the ANS. The investigator will determine whether single-pulse TMS of the primary motor cortex in the dominant hemisphere in healthy, young adults will affect 1)…
- Trial name
- NCT02833220
- Testing
- Single-Pulse Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
TBI (Traumatic Brain Injury), Ocular Motility Disorders
Frontoparietal Priority Maps as Biomarkers for MTBI
The purpose of this study is to determine whether there is a quantitative relationship between brain processes seen by a MRI and visual deficits caused by mild to moderate traumatic brain injuries (mTBI).
- Trial name
- NCT02251002
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Minnesota