Clinical trials: sponsored by University of Minnesota
Sexual and Reproductive Health, Disability
Evaluation of a Disability-Focused Sexual and Reproductive Health Curriculum for Health Students in Tanzania
This randomized controlled trial will evaluate the efficacy of a three-day sexual and reproductive health curriculum focused on persons with disabilities and tailored to the Tanzanian context.
- Conditions
- Sexual and Reproductive Health, Disability, Health Knowledge, Attitudes, Practice, Health Education
- Trial name
- NCT07772778
- Testing
- Disability-Focused Sexual and Reproductive Health Curriculum
- Where
- Tanzania
- Volunteers
- 412 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Renal Transplant Rejection
Multi-Parametric MRI for Renal Transplantation
The goals of this study are: To optimize and evaluate multiple kidney MRI methods; and To investigate the potential of MRI in the assessment of transplant kidney functions; To achieve these goals, we will perform pilot MRI…
- Trial name
- NCT03192007
- Testing
- Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- University of Minnesota
Opioid Use Disorder, Stimulant Use Disorder
Contingency Management for Opioid and Stimulant Use Disorders in Primary Care
Contingency management (CM) is a behavioral intervention that involves incentivizing participants for target behaviors in a clinical setting.
- Trial name
- NCT05288751
- Testing
- Contingency Management
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of Minnesota
Pain, Depression
Transdiagnostic Cognitive Biomarkers
The overall objective of this study is to determine the feasibility of identifying transdiagnostic biomarkers of cognitive function mediated by neuromodulation of the dorsolateral prefrontal cortex that are translatable across…
- Trial name
- NCT04864080
- Testing
- Computer game/task, Health surveys online
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Sexual and Reproductive Health, Health Knowledge, Attitudes, Practice
Evaluating the Effects of Reproductive Health Training on Provider Behavior - Aim 3
This study will evaluate the real-world effectiveness of a four-day Afrocentric sexual and reproductive health curriculum for health professional students in Tanzania.
- Conditions
- Sexual and Reproductive Health, Health Knowledge, Attitudes, Practice, Provider Behavior, Health Education
- Trial name
- THP-2 Aim 3 (NCT07770438)
- Testing
- Afrocentric Sexual and Reproductive Health Curriculum
- Where
- 3 sites in Tanzania
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Gut Health, Gastrointestinal Symptoms
Intermediate Wheatgrass Products and Gut Health
This study will evaluate the effect of daily consumption of intermediate wheatgrass-based products on measures of gut health compared with whole wheat-based products in healthy adults with traditional western fiber intake.
- Conditions
- Gut Health, Gastrointestinal Symptoms, Gut Microbiome, Dietary Fiber
- Trial name
- IWG Gut Health (NCT07773441)
- Testing
- Intermediate Wheatgrass-Based Products, Whole Wheat-Based Products
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Bulimia Nervosa
Neurobiological and Psychological Maintenance Mechanisms Associated With Anticipatory Reward in Bulimia Nervosa
The purpose of this investigation is to identify the potentially crucial role of anticipatory reward mechanisms maintaining bulimic behavior (i.e., binge eating and purging) in bulimia nervosa (BN).
- Trial name
- NCT04917068
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Stroke
Phase-dependent Evaluation of Motor Cortex Excitability With TMS in Stroke
The purpose of this study is to investigate the effects of transcranial magnetic stimulation (TMS) on motor cortex excitability in individuals who have suffered stroke and to study the influence of the phase of the oscillatory…
- Trial name
- NCT04968743
- Testing
- Transcranial magnetic stimulation (TMS)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Prematurity
Maternal Stress, Milk Composition, and Preterm Neurodevelopment
This study explores the associations between maternal stress, breastmilk composition, and feeding and neurodevelopment for preterm infants in the NICU and at 4 months corrected age.
- Trial name
- NCT05537454
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Minnesota
Premature, Premature Lungs
Baby ABS (Abdominal Binder Study)
The primary outcome of this study is to determine if the use of the FDA-approved DandleLion NeoBellyBand increases the thickness of the rectus abdominis muscle in premature babies receiving continuous positive pressure…
- Conditions
- Premature, Premature Lungs, Ventilator Lung; Newborn, Rectus Abdominis
- Trial name
- NCT07049900
- Testing
- NeoBelly Band
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Minnesota
Cancer
ConnectedNest: a Digital Platform Connecting Individuals With Cancer to Social Care
Social determinants of health (SDoH) such as housing instability, food insecurity, and financial burden largely shape the health and well-being of individuals, create health inequities, and drive a large portion of avoidable…
- Trial name
- NCT06559228
- Testing
- ConnectedNest, Standard of care
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of Minnesota
Dental Anesthesia
MRI and Local Anesthesia
The purpose of this research is to investigate the utility of using dental-dedicated MRI as a measurement tool to observe and evaluate the administration of local anesthesia in dental patients.
- Trial name
- MRI and LA (NCT07602686)
- Testing
- ddMRI
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Minnesota
Stroke, Ischemic Stroke
Feasibility of a First-Line Physical Activity Intervention After Stroke
The goal of this study is to explore a new intervention that supports physical activity within the first 6 weeks after stroke. All participants will complete assessments at weeks 0 and 7.
- Conditions
- Stroke, Ischemic Stroke, Hemorrhagic Stroke
- Trial name
- PA-ChatS (NCT06679803)
- Testing
- Physical Activity Chats after Stroke (PA-ChatS)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Minnesota
Stroke
teleABLE to Reduce Post-Stroke Sedentary Behavior
The goal of this clinical trial to test whether a remotely delivered behavioral activation-based intervention called "teleABLE" works better than a health education intervention for (1) reducing sitting time and (2) improving…
- Trial name
- NCT06312709
- Testing
- teleABLE (telehealth-delivered Activating Behavior for Lasting Engagement), Health Education
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Minnesota
Blood Donation
Docudrama for Blood Donation in Ghana (DDID)
A cluster pilot RCT to evaluate the effectiveness of the docudrama compared to a control group (usual engagement with blood services) on repeat blood donation attempts among first-time blood donors.
- Trial name
- DDID (NCT07093307)
- Testing
- Docudrama, Control
- Where
- Ghana
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Smoking
Feasibility of Conducting a Pilot Telehealth Study Assessing the Removal of Filter Ventilation on Smoking Behavior and Biomarkers in Menthol Smokers Switched to Non-menthol Cigarettes
This decentralized clinical trial assesses the feasibility of conducting a tobacco product evaluation study remotely via telehealth visits and mailed samples.
- Trial name
- NCT04514471
- Testing
- Minimally Ventilated non-menthol cigarettes, Ventilated non-menthol cigarettes
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Peripheral Artery Disease
Community-based Exercise Following Revascularization for PAD
The primary goal of this clinical trial is to evaluate whether a community-based structured exercise therapy (CB-SET) intervention, which could be accessible and easily disseminated, adds benefit to peripheral artery disease…
- Trial name
- NCT04252950
- Testing
- CB-SET, Revascularization
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Minnesota
Crohn Disease
Standardized Microbiota Transplant Therapy in Crohn's Disease
Crohn's disease (CD) develops because of a disruption of homeostasis between the gut microbiota and the host immune system resulting in excessive inflammation in the intestinal tract.
- Trial name
- NCT06631586
- Testing
- MTP-101C, MTP-101S
- Where
- 3 sites in United States
- Volunteers
- 120 people
- Sponsor
- University of Minnesota
Obesity, Pregnancy
Maternal Obesity, Breast Milk Composition, and Infant Growth
Today the majority of pregnant women in the United States are either overweight or obese at conception with their offspring having greater adiposity at birth, a 2-fold greater risk of later obesity, and neonatal insulin…
- Conditions
- Obesity, Pregnancy, Breastmilk Collection, Infant Overnutrition
- Trial name
- (MILK) (NCT03301753)
- Where
- 2 sites in United States
- Volunteers
- 2,050 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Coccidioidomycosis, Blastomycosis
Platform Trial for Salvage Consolidation Therapy in Dimorphic Fungi
This Phase II platform trial will evaluate the safety, tolerability, and effectiveness of investigational antifungal agents as salvage or consolidation therapy in adults with dimorphic fungal infections, including…
- Conditions
- Coccidioidomycosis, Blastomycosis, Histoplasmosis, Dimorphic Fungal Infection
- Trial name
- NCT07804368
- Testing
- Oteseconazole
- Where
- 4 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of Minnesota
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