Clinical trials: sponsored by University of Nebraska
Neoplasms Malignant
Perceptions, Experiences, and Activity in CancEr Survivors During COVID-19
To examine perceptions and determinants of physical activity during the COVID-19 pandemic among cancer survivors.
- Trial name
- PEACE (NCT04637295)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Nebraska
Insulin Resistance, Stress, Psychological
Predicting Insulin Resistance in American Indian Youth
The purpose of this study is to identify risks that may contribute to increased insulin resistance which may help explain some of the increased incidence of type 2 diabetes in American Indian Youth, at the Rosebud reservation…
- Trial name
- NCT00498030
- Where
- United States
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Stage IA Breast Cancer, Stage IB Breast Cancer
Cyclophosphamide and Paclitaxel With or Without Trastuzumab in Stage I-II Breast Cancer Who Have Undergone Surgery
This phase II trial studies the side effects and how well giving cyclophosphamide and paclitaxel with or without trastuzumab works in treating patients with stage I-II breast cancer who have undergone surgery.
- Conditions
- Stage IA Breast Cancer, Stage IB Breast Cancer, Stage IIA Breast Cancer, Stage IIB Breast Cancer
- Trial name
- NCT01106898
- Testing
- cyclophosphamide, paclitaxel, trastuzumab
- Where
- 2 sites in United States
- Volunteers
- 112 people
- Sponsor
- University of Nebraska
Arthritis
Followup of Glenoid Fix Utilizing Auto Bone Graft in Shoulder Replacement
This is a case study to evaluate the adequacy of fixation and functional outcome of the glenoid anchor peg following autologous bone grafting around the prosthesis at the time of implant.
- Trial name
- NCT00670852
- Testing
- X-rays and CT scan
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Recurrent Small Cell Lung Carcinoma
Topotecan Hydrochloride and Doxorubicin Hydrochloride in Treating Relapsed or Refractory Small Cell Lung Cancer
This phase I trial studies the side effects and best dose of topotecan hydrochloride when given together with doxorubicin hydrochloride in treating patients with small cell lung cancer (SCLC) that has come back after a period of…
- Trial name
- NCT00856037
- Testing
- Doxorubicin Hydrochloride, Laboratory Biomarker Analysis, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Nebraska
Recurrent Non-Small Cell Lung Carcinoma, Stage IV Non-Small Cell Lung Cancer
Vinorelbine Tartrate and Paclitaxel in Treating Older Patients With Advanced Non-Small Cell Lung Cancer
This phase II trial studies the side effects and how well vinorelbine tartrate and paclitaxel works in treating older patients with non-small cell lung cancer that has spread to other placed in the body.
- Trial name
- NCT00602797
- Testing
- Paclitaxel, Quality-of-Life Assessment, Questionnaire Administration
- Where
- 5 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Nebraska
Lung Cancer
CT Scans in Screening for Lung Cancer in Current and Former Smokers
RATIONALE: Screening tests, such as CT scanning, may help doctors find cancer cells early and plan better treatment for lung cancer.
- Trial name
- NCT00625690
- Testing
- questionnaire administration, computed tomography, evaluation of cancer risk factors
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Nebraska
Non-Hodgkin's Lymphoma
Dasatinib in Relapsed or Refractory Non-Hodgkin's Lymphoma
Primary Objective: To determine the maximum tolerated dose (MTD) of Dasatinib in relapsed or refractory non-hodgkin's lymphoma (NHL) patients and to determine the safety of Dasatinib in NHL.
- Trial name
- NCT00550615
- Testing
- Dasatinib, Dasatinib Maximum Tolerated Dose
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Nebraska
Multiple Chronic Conditions
Self-Management Interventions Using Mobile Health for the Multimorbid
The purpose of this pilot study is to evaluate the feasibility and impact of delivering mobile health self-management interventions to improve adherence to the prescribed treatment in a multimorbid population returning home after…
- Trial name
- NCT04566107
- Testing
- mHealth intervention, mHealth Plus
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of Nebraska
Mucositis
Impact of Oral Hygiene Gels on Peri-implant Mucositis
Peri-implant mucositis is abnormal inflammation occurring around dental implants, increasing the risk of loss of bone support. The purpose of this study is to evaluate the impact of brushing the bacterial biofilm at the…
- Trial name
- NCT03243591
- Testing
- Livionex gel, Aquafresh gel
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Hypotension on Induction
Chronic Angiotensin Converting Enzyme Inhibitors in Intermediate Risk Surgery
Primary research hypothesis: Patients who continue their chronic ACEI therapy up to and including the morning of a non-cardiac, non-vascular surgery will experience more intraoperative hypotension than those who transiently hold…
- Trial name
- NCT01669434
- Testing
- ACEI continuation, ACEI omission
- Where
- United States
- Volunteers
- 291 people
- Sponsor
- University of Nebraska
Coronary Heart Disease, Cardiac Rehabilitation
Reducing Risk in Cardiac Rehabilitation: Partners Together in Health (PaTH) Intervention Study
The objective of the proposed study, using an experimental, two-group (n = 30 couples in each group) repeated measures design, was to pilot test the effects of the PaTH Intervention versus a usual care group in improving the…
- Trial name
- PaTH (NCT00926848)
- Testing
- Partners Together in Health (PaTH) Intervention
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Moderate to Advanced Chronic Periodontitis
Local Minocycline to Reduce Future Inflammation and Bone Loss in Periodontal Maintenance Patients
The purpose of this study is to determine the effect of local application of minocycline microspheres on the periodontal inflammation and bone loss prevention in patients diagnosed with moderate-severe chronic periodontitis…
- Trial name
- NCT01647282
- Testing
- locally-applied minocycline HCl (1 mg), scaling and root planing (Sc/RP)
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of Nebraska
Breast Cancer, Psychological Adjustment
Reducing Distress and Depressive-symptoms in Rural Women
Approximately 30% of U.S. breast cancer survivors experience significant cancer-related distress ranging from adjustment disorders, depression-symptoms and major depression up to 20 years after diagnosis.
- Trial name
- NCT03465813
- Testing
- CaringGuidance After Breast Cancer Diagnosis
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Nebraska
Heart Failure
Balance Training for Elders With Heart Failure
Falls are the leading cause of injury-related deaths in older (≥ 65 y/) community dwelling heart failure (HF) patients. Fall risks are even greater for those with HF due to decreased exercise capacity, loss of skeletal muscle \&…
- Trial name
- BASIC (NCT02566785)
- Testing
- Balance Intervention
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Nebraska
Substance-related Disorders, Alcohol-related Disorders
Specialized Substance Abuse Supervision (SSAS) Versus Non-SSAS Recidivism Rates Among Nebraska Felony Drug Offenders
This social science study hypothesizes that convicted felony drug offenders in Nebraska who participated in Specialized Substance Abuse Supervision (SSAS) as part of their probation or parole showed significantly better outcomes…
- Trial name
- SSAS (NCT00690352)
- Testing
- Specialized Substance Abuse Supervision (SSAS)
- Where
- United States
- Volunteers
- 344 people
- Sponsor
- University of Nebraska
Kawasaki Disease, Heart Disease
Real Time Myocardial Contrast Echocardiography and Dobutamine Stress Perfusion Magnetic Resonance Imaging
The present study is designed to: 1. investigate the safety and efficacy of Real time myocardial echocardiography (RT-MCE) in adolescents and adults ages 12-50 with congenital and acquired congenital heart disease 2.
- Trial name
- ECHOBIKE (NCT00861848)
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Chronic Pancreatitis, Osteopenia
Bone Disease in Chronic Pancreatitis: A Complex Phenomenon
The purpose of this study is to define the prevalence of low bone density (osteopenia/osteoporosis) in patients with chronic pancreatitis.
- Conditions
- Chronic Pancreatitis, Osteopenia, Osteoporosis
- Trial name
- NCT02108509
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of Nebraska
Breast Cancer
Neoadjuvant/Adjuvant Chemotherapy, Vaccine & Adjuvant Radiation Therapy in p53-Overexpressing Stage III Breast Cancer
RATIONALE: Vaccines may make the body build an immune response to kill tumor cells. Drugs used in chemotherapy, such as doxorubicin, cyclophosphamide, and paclitaxel, work in different ways to stop tumor cells from dividing so…
- Trial name
- NCT00082641
- Testing
- autologous dendritic cell-adenovirus p53 vaccine
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Nebraska
Anaplastic Large Cell Lymphoma, Angioimmunoblastic T-cell Lymphoma
Combination Chemotherapy and Pralatrexate as First-Line Therapy in Treating Patients With Non-Hodgkin Lymphoma
This phase II trial studies how well combination chemotherapy and pralatrexate works in treating patients with non-Hodgkin lymphoma (NHL).
- Conditions
- Anaplastic Large Cell Lymphoma, Angioimmunoblastic T-cell Lymphoma, Hepatosplenic T-cell Lymphoma, Peripheral T-cell Lymphoma
- Trial name
- NCT01336933
- Testing
- prednisone, cyclophosphamide, etoposide
- Where
- 9 sites in United States
- Volunteers
- 34 people
- Sponsor
- University of Nebraska