Clinical trials: sponsored by University of Oklahoma
Smoking, Cigarette
Dyadic Financial Incentive Treatments for Dual Smoker Couples
Smokers partnered with other smokers (i.e., dual-smoker couples) represent ~2/3 of all smokers. Dual-smoker couples (DSCs) are less likely to try to quit smoking and more likely to relapse during a quit attempt, reducing overall…
- Trial name
- NCT06296849
- Testing
- Financial Incentive Treatment (FIT)
- Where
- 2 sites in United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Tobacco Use Disorder, Nicotine Dependence
Beta-Adrenergic Modulation of Drug Cue Reactivity
This study is designed to investigate the effects of a beta-adrenergic antagonist (Propranolol; 40 mg IR) and nicotine patch (14 mg) administered alone and in combination on neurobiological and behavioral responses to smoking…
- Conditions
- Tobacco Use Disorder, Nicotine Dependence, Cigarette Smoking
- Trial name
- NCT05587361
- Testing
- Propranolol, Nicotine Patch
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Refractory Amblyopia
Evaluation of Echothiophate in Pediatric Patients With Refractory Amblyopia
The goal of this clinical trial is to see if a medicine called echothiophate iodide (Phospholine Iodide) can help treat children with refractory amblyopia.
- Trial name
- NCT07554131
- Testing
- Echothiophate Iodide 0.125% Ophthalmic Solution
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Oklahoma
Older, Adults
Postural Control in Adults
The investigators propose a 2-week intervention involving adults over 65 years old. Participants will undergo dynamic balance training on an movable platform (stabilometer) with either restricted or full vision.
- Conditions
- Older, Adults, Older Adults, Balance
- Trial name
- NCT07554118
- Testing
- restricted vision (no-V), full vision (full-V)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Nightmare, Suicidal Ideation
Cognitive-Behavioral Therapy for Children With Nightmares
The goal of this clinical trial is to assess the efficacy of CBT-NC intervention to determine its impact on mental health and suicidality in children ages 6-17.
- Conditions
- Nightmare, Suicidal Ideation, Children, Only
- Trial name
- NCT06033781
- Testing
- Cognitive Behavioral Therapy for Nightmares in Children
- Where
- 2 sites in United States
- Volunteers
- 57 people
- Sponsor
- University of Oklahoma
Acute Lymphocytic Leukemia, Acute Myeloid Leukemia
Pilot Imaging Study of Leukemia
This is a prospective pilot study, the primary aim of which is to determine whether the presence of 18F FLT imaging signal uptake abnormalities correlate with clinically validated evidence of hematopoietic malignant disease (e.g.
- Conditions
- Acute Lymphocytic Leukemia, Acute Myeloid Leukemia, Ambiguous Lineage Leukemia or Lymphoma, Myeloma
- Trial name
- REALIZE (NCT03633955)
- Testing
- FLT
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of Oklahoma
Hyperglycemia, Hematopoietic Stem Cell Transplantation
Glucose Control In Hematopoetic Stem Cell Transplant
To determine whether intensive glucose control results in improved mortality and reduced hospital stay length by performing a randomized trial of intensive glucose management (blood glucose goal 110 mg/dl) using continuous IV…
- Trial name
- NCT00582036
- Testing
- Regular Insulin, Deployment of the MiniMed Paradigm monitoring device
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Oklahoma
Claudication, Peripheral Artery Disease
The Effects of Diet and Exercise Interventions in Peripheral Artery Disease
This study is a 3-month, prospective, randomized controlled clinical trial designed to address the efficacy of the DASH dietary program combined with a home-based exercise program, quantified by a step activity monitor, to…
- Trial name
- NCT03845036
- Testing
- DASH Diet plus Home-Based Exercise, Home-Based Exercise
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Oklahoma
Healthy Aging, Fatigue
Neuromodulation and Fatigue
In this project, we aim to determine any potential effects of a weak electrical current applied to the neck or thoracic area on functional capacity and muscle activation.
- Trial name
- NCT05487131
- Testing
- electrical stimulation
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Cardiac Arrhythmia, Qt Interval, Variation in
Using an iPhone ECG to Monitor the QT Interval on Dofetilide and Sotalol Patients
This study will validate the recording accuracy of a specific electrical interval of the heart, the QT interval, between an iPhone rhythm strip recording and a traditional 12-lead electrocardiogram (ECG).
- Trial name
- NCT02241252
- Testing
- iPhone ECG
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Cervical Dysplasia
Smoking Cessation in Women With Gynecological Conditions
This feasibility study will compare two smoking cessation methods, traditional nicotine replacement therapy and Electronic Nicotine Delivery Systems (electronic cigarettes) in patients with gynecological conditions.
- Trial name
- NCT01989923
- Testing
- Nicotine Replacement Therapy, Electronic Cigarettes
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Pelvic Organ Prolapse
The Purpose of This Study is to Look at Pelvic Support Problems, Also Commonly Known as Pelvic Organ Prolapse
FemmeJock is a pelvic floor support system developed by pelvic floor physiotherapists for patients with pelvic organ prolapse in order to ameliorate symptoms of pelvic floor pressure and discomfort.
- Trial name
- NCT00964197
- Testing
- FemmeJock
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Atrial Fibrillation
Dual Versus Single Shock for Cardioversion of Atrial Fibrillation
The investigators aim to investigate the immediate success rate (rate of termination of atrial fibrillation) of dual shock cardioversion compared with standard single shock cardioversion in patients with baseline characteristics…
- Trial name
- NCT03943693
- Testing
- Double shock, Single shock
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Oklahoma
Atherosclerosis, Angioplasty
Local Paclitaxel Delivery for SFA Disease
To see if restenosis rates of superficial femoral artery atherosclerosis with percutaneous techniques can be improved using paclitaxel.
- Conditions
- Atherosclerosis, Angioplasty, Peripheral Arterial Disease
- Trial name
- IRRITAX (NCT00821028)
- Testing
- Paclitaxel
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Oklahoma
Anesthesia, General, Memory
Depth of Anesthesia on Implicit Memory
Purpose of this study is to see if different levels of anesthesia have an effect on hearing spoken words without awareness of having heard them or anxiety after surgery.
- Trial name
- NCT00584324
- Testing
- BIS 40, BIS 60
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Oklahoma
Secondhand Smoke
Novel Methods to Reduce Children's Secondhand Smoke Exposure II
The overall aim of the current study is to determine if the use of nicotine containing products by caregivers who smoke and who are not interested in quitting, is effective in reducing children's secondhand smoke exposure.
- Trial name
- EZII (NCT01896518)
- Testing
- Nicotine polacrilex, Tobacco lozenge
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Kidney Transplant, Type 2 Diabetes
Sitagliptin Treatment in Patients With Type 2 DM After Kidney Transplant
This study is designed to look at the effect sitagliptin has on tacrolimus and sirolimus drug levels in kidney transplant patients. It is also designed to look at the side effects experienced in the transplant population.
- Trial name
- NCT00466518
- Testing
- Administration of sitagliptin
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Oklahoma
Secondhand Smoke
Preliminary Investigation of Novel Methods to Reduce Children's Secondhand Smoke Exposure
The overall aim of the current study is to determine if the use of nicotine containing products by caregivers who smoke and who are not interested in quitting, is effective in reducing children's secondhand smoke exposure.
- Trial name
- EZI (NCT01935713)
- Testing
- Nicotine polacrilex, Electronic Cigarette, Dissolvable Tobacco Lozenge
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Stroke
Evaluation of Vibration-based Wearable Upper Limb Rehabilitation Device
The investigators will perform a pilot 4-week at home study with 48 individuals with stroke and 10 therapists working with stroke patients to examine the feasibility and effect of a wearable focal muscle vibration device on upper…
- Trial name
- NCT04698369
- Testing
- Vibration Massage Therapy
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Oklahoma
Healthy Eating
Breath Hydrogen and Methane as Biomarkers of Fiber Intake
This study is designed to examine if mobile phone-based breath hydrogen and methane monitors can be used as a biomarker of dietary fiber intake.
- Trial name
- NCT07375329
- Testing
- Breath Tester
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Oklahoma