Clinical trials: open to volunteers, sponsored by University of Pittsburgh
Chronic Kidney Disease, Cardiovascular Disease
Feasibility of The Health Integrated Nutrition and Kidney Wellness Program
Purpose of the Study: This clinical trial will test whether a nutrition and kidney health program can work well for adults with kidney disease. The program was created with help from patients and community partners.
- Trial name
- THINK-Well (NCT07518719)
- Testing
- THINK-Well, Enhanced Usual Care
- Where
- 5 sites in United States
- Volunteers
- 45 people
- Sponsor
- University of Pittsburgh
Abdominal Surgery
Pip Care to Improve Surgical Patient Outcomes
Pip Care is developing a personalized, interactive surgical journey platform with a live health coach that works directly with health systems to optimize the perioperative care process.
- Trial name
- NCT06661291
- Testing
- Pip Care Digital Health Platform, Standard of Care Protocol
- Where
- 8 sites in United States
- Volunteers
- 900 people
- Sponsor
- University of Pittsburgh
Speech Impairment, Speech Disorder
Voiceitt for People With Impairments in Speech
The primary objective of this pilot study is to evaluate the feasibility and preliminary effectiveness of the Voiceitt app in improving communication for individuals with speech impairments due to conditions such as cerebral…
- Trial name
- NCT06874322
- Testing
- Voiceitt
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Pittsburgh
Childhood Obesity, Evidence-Based Practice
Network-Based Support to Help Community Coalition Members Choose and Use Strategies to Improve Child Health
Community coalitions bring together residents and organizations to improve child health, but they may need support to identify and put research-supported strategies into practice.
- Conditions
- Childhood Obesity, Evidence-Based Practice, Food Systems, Food Policy
- Trial name
- NCT07804550
- Testing
- Catalyzing Communities, FICAS Implementation Intervention
- Where
- United States
- Volunteers
- 3,300 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Spinal Cord Injuries, Cerebral Palsy
Mobile Health Self-Management and Support System for Chronic and Complex Health Conditions
This study will assess the benefits of using mobile health system designed for individuals with chronic and complex health conditions (such as those with Spinal Cord Injury,Cerebral Palsy, Spina Bifida, and Traumatic Brain…
- Conditions
- Spinal Cord Injuries, Cerebral Palsy, Spinal Dysraphism, Brain Injuries
- Trial name
- NCT02592291
- Testing
- MHealth
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Stuttering, Childhood
Speech Signals in Stuttering
The purpose of this research study is to understand how speech and language are processed in the brain. This study will provide information that may help with the understanding how speech and language are processed in children…
- Trial name
- NCT05668923
- Testing
- Speech sound stimulation
- Where
- 2 sites in United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Pulmonary Fibrosis
Genetic Polymorphisms in Idiopathic Pulmonary Fibrosis (IPF)
The purposes of this study are: to determine if there are specific genetic traits that might explain why patients have developed pulmonary fibrosis; to determine if specific genetic traits account for differing patterns of…
- Trial name
- GP (NCT00258570)
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- University of Pittsburgh
Lung Diseases, Interstitial
Dorothy P. and Richard P. Simmons Center for ILD Research Registry
The purpose of this study is to place past, current, and future medical record information into the UPMC Simmons Center for Interstitial Lung Disease Research Registry.
- Trial name
- ILDRR (NCT00258583)
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- University of Pittsburgh
Idiopathic Pulmonary Fibrosis
Genomic and Proteomic Analysis of Disease Progression in Idiopathic Pulmonary Fibrosis (IPF)
The purpose of the study is to identify genetic and biologic markers that may predict the loss of lung function due to idiopathic pulmonary fibrosis.
- Trial name
- GAP (NCT00373841)
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- University of Pittsburgh
Chronic Kidney Disease Requiring Hemodialysis
Technology Assisted Collaborative Care Intervention to Improve Patient-centered Outcomes in Dialysis Patients
The goal of this study is to learn if a collaborative care intervention of pharmaco-therapy and/or cognitive behavioral therapy (CBT), delivered in a real-world setting, improves symptoms of pain, fatigue and/or depression.
- Trial name
- TACcare 2 0 (NCT06978127)
- Testing
- Technology Assisted Stepped Collaborative Care, Usual Care Arm
- Where
- 2 sites in United States
- Volunteers
- 424 people
- Sponsor
- University of Pittsburgh
Depression
Cognitive Training as an Adjunct to Ketamine in Real-world Clinics
In a sample of patients already receiving ketamine (or esketamine) treatment as part of their clinical care, this project seeks to test whether we can enhance and/or extend (es)ketamine's rapid effects by introducing helpful…
- Trial name
- NCT06526078
- Testing
- Cognitive Training
- Where
- 3 sites in United States
- Volunteers
- 600 people
- Sponsor
- University of Pittsburgh
Glaucoma and Ocular Hypertension
Clarifying the Optimal Application of SLT Therapy Trial
The goal of this study is to understand if SLT performed at low energy is as effective as SLT performed at standard energy, and also to see if repeating SLT at low energy once a year will prevent or delay the need for daily eye…
- Trial name
- COAST (NCT04967989)
- Testing
- Low Energy SLT, Standard Energy SLT
- Where
- 29 sites in United States, Canada
- Volunteers
- 790 people
- Sponsor
- University of Pittsburgh
Cyclic Vomiting Syndrome
Cortical Excitability in Cyclic Vomiting Syndrome
This exploratory study will determine if there are differences in cortical excitability between patients suffering from cyclic vomiting syndrome (CVS) and healthy control subjects, as assessed by a non-invasive method of brain…
- Trial name
- NCT05256160
- Testing
- TMS Paired-Pulse assessment of cortical excitability, Autonomic activity
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Autism, Sleep Disturbance
The Power Down Pilot Study: A Novel Bedtime Manipulation Protocol
The goal of this pilot intervention study is to examine the feasibility and acceptability of a novel bedtime manipulation protocol called "The Power Down" for autistic youth, ages 6-10.
- Trial name
- NCT06386029
- Testing
- Power Down bedtime manipulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Pittsburgh
Inflamatory Bowel Disease (Crohn's and Ulcerative Colitis)
Inflammatory Bowel Disease (IBD) Research Registry
Patients seen at the Center for Inflammatory Bowel Disease will be asked to provide their written informed consent (authorization) to allow their identifiable medical record information related to their Inflammatory Bowel Disease…
- Trial name
- NCT04243525
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- University of Pittsburgh
Nocturia, Insomnia
Addressing Nocturia in Older Women Utilizing Behavioral Sleep Intervention and Brief Mindfulness
The goal of this clinical trial is to examine and compare the effect of behavioral sleep treatment: BBTI (brief behavioral treatment of insomnia) and brief mindfulness (MI), independently and combined vs control on frequency of…
- Trial name
- ANOWSM (NCT07760779)
- Testing
- Brief behavioral treatment of insomnia, MI, Control
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Pittsburgh
Cognitive Ability General, Functional Abilities
Automated IADL Sensing to Refine Measurement of Older Adult Daily Activity
The instrumental activities of daily living (IADL) refer to complex daily activities required for adult independence, such as preparing a meal or taking medications.
- Trial name
- NCT07585864
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Solid Organ Transplantation, Bone Marrow Transplantation
Biomarkers in Transplant Recipients to Improve Outcomes
The objective of this study is to evaluate whether certain proteins, expressed in biological tissues can indict a better understanding of the effect of drugs that are used to treat rejection, and of processes leading to rejection…
- Trial name
- NCT01163578
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- University of Pittsburgh
Biliary Atresia
Mapping Disease Pathways for Biliary Atresia
This project will primarily evaluate the developmental/genetic basis of biliary atresia, the most common cause of liver failure at birth, and which accounts of half of all liver transplants performed worldwide in children.
- Trial name
- BA (NCT03273049)
- Where
- United States
- Volunteers
- 1,100 people
- Sponsor
- University of Pittsburgh
Childhood Liver Cancer, Liver Malignant Tumors
Molecular Basis of Pediatric Liver Cancer
The purpose of this retrospective and prospective project is to understand the molecular and genetic basis of liver cancer of childhood.
- Conditions
- Childhood Liver Cancer, Liver Malignant Tumors, Embryonal Sarcoma of Liver (Disorder), Hepatoblastoma
- Trial name
- NCT03959800
- Where
- United States
- Volunteers
- 1,600 people
- Sponsor
- University of Pittsburgh