Clinical trials: sponsored by University of Rochester
Asthma
School-Based Preventive Asthma Care Technology: A Trial Using a Novel Technology to Improve Adherence
The goal of this new translational project is to test the feasibility and effectiveness of implementing school-based directly observed therapy of preventive asthma medications in a real-world setting, using state-of-the-art…
- Trial name
- SB-PACT (NCT01175434)
- Testing
- School-Based Medication Delivery
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- University of Rochester
Depression
Women's Depression Treatment Study
The aim of the Women's Depression Treatment Study, based in a community mental health center, is to evaluate the effectiveness of Interpersonal Psychotherapy-Trauma in Community Settings (IPT-TCS) on improving depression and…
- Trial name
- NCT00843700
- Testing
- Interpersonal Psychotherapy-Trauma in Community Settings, Treatment as Usual
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- University of Rochester
Depression
Comparison of Two Psychotherapy Treatments for Depressed Women With a History of Sexual Abuse
This study will compare the effectiveness of individual versus interpersonal psychotherapy in treating depressed women with a history of sexual abuse.
- Trial name
- NCT00257400
- Testing
- Interpersonal Psychotherapy (IPT), Individual Psychotherapy
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Rochester
Healthy
Ozone Cardiovascular Effects in Genetically Susceptible People
Increases in air pollution are associated with increases in deaths from cardiovascular disease, but the investigators know little about how ozone air pollution affects the cardiovascular system.
- Trial name
- OZCARD (NCT01192477)
- Testing
- Ozone
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Child Abuse
Preventing Child Abuse in Infants
The purpose of this study is to compare 2 approaches (interventions) to prevent child-abuse (maltreatment) in infants: Psychoeducational Home Visitation (PHV) vs Infant-Parent Psychotherapy (IPP).
- Trial name
- NCT00000382
- Testing
- Infant-Parent Psychotherapy, Child Protective Services, Psychoeducational Home Visitation
- Sponsor
- University of Rochester
Chronic Graft Versus Host Disease
Positron Emission Tomography - Computed Tomography (PET-CT) Scanning in Chronic Graft Versus Host Disease (cGvHD)
Graft versus Host Disease (GvHD), in both its acute and chronic forms, is the major intrinsic complication of allogeneic hematopoeitic stem cell transplant (allo-HSCT).
- Trial name
- NCT01964625
- Testing
- PET-CT Scan
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Rochester
Leukemia
Cladribine, Cytarabine, and Imatinib Mesylate in Treating Patients With Refractory or Relapsed Acute Myeloid Leukemia or Blastic Phase Chronic Myelogenous Leukemia
RATIONALE: Drugs used in chemotherapy, such as cladribine and cytarabine, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00258271
- Testing
- filgrastim, cladribine, cytarabine
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Rochester
Osteoporosis, Prostate Cancer
Effect of Androgen Suppression on Bone Loss in Patients With or Without Bone Metastases Secondary to Prostate Cancer
RATIONALE: Assessing the effect of androgen suppression on bone loss in prostate cancer patients may improve the ability to plan treatment, may decrease the risk of fractures and bony pain, and may help patients live more…
- Trial name
- NCT00003903
- Testing
- management of therapy complications
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Rochester
Colorectal Cancer
GM-CSF and Combination Chemotherapy in Treating Patients Who Are Undergoing Surgery for Stage II or Stage III Colon Cancer
RATIONALE: Colony-stimulating factors, such as GM-CSF, may increase the number of immune cells found in bone marrow or peripheral blood and may help the immune system recover from the side effects of chemotherapy or kill tumor…
- Trial name
- NCT00262808
- Testing
- sargramostim, fluorouracil, leucovorin calcium
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of Rochester
Active Chronic Graft Versus Host Disease
Pentostatin, Cyclophosphamide Plus Rituximab (PCR) for the Therapy of Poor-Prognosis Chronic Graft-Versus-Host Disease
Chronic graft-versus-host disease (GvHD) is a severe, life threatening complication from getting a bone marrow or stem cell transplant. It is caused by certain cells from the donor that attack your cells.
- Trial name
- NCT01001780
- Testing
- Pentostatin; Cyclophosphamide; Rituximab
- Where
- United States
- Sponsor
- University of Rochester
Lymphoma
Rituximab Plus Interleukin-2 in Treating Patients With Lymphoma
RATIONALE: Monoclonal antibodies can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells.
- Trial name
- NCT00003356
- Testing
- aldesleukin, rituximab
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- University of Rochester
Esophageal Cancer
Gefitinib in Treating Patients With Stage I, Stage II, or Stage III Esophageal Cancer That Can Be Removed By Surgery
RATIONALE: Gefitinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving gefitinib before surgery may shrink the tumor so that it can be removed.
- Trial name
- NCT00258297
- Testing
- gefitinib, conventional surgery, enzyme inhibitor therapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Rochester
Cardiovascular Diseases
Assessing the Effectiveness of Concurrent Peer Review for Patients With Cardiovascular Disease and Diabetes
We will assess the impact of concurrent peer review vists on blood pressure, cholesterol and diabetes control. Concurrent peer review (CPR) visits refer to special offic visits by patients to a clinician (physician, nurse…
- Trial name
- NCT00508014
- Testing
- Usual Care, Concurrent Peer Review visit
- Where
- United States
- Volunteers
- 727 people
- Sponsor
- University of Rochester
Cardiovascular Disease
Fish Oil and Aspirin With Type 2 Diabetes
The purpose of this study is to understand if omega-3 fatty acids in fish oil enhance the ability of aspirin to reduce the risk of cardiovascular diseases such as heart attack and stroke in those who have diabetes mellitus.
- Trial name
- R-21 (NCT01181882)
- Testing
- Fish Oil and Aspirin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Rochester
Psoriasis
Conditioning, the Placebo Effect, and Psoriasis
This study uses the psychological principle known as classical conditioning to try to improve the standard treatment of psoriasis.
- Trial name
- NCT00005922
- Testing
- Partial schedule of pharmacotherapeutic reinforcement, Dose control for Arm B, Standard pharmacotherapeutic protocol
- Where
- 2 sites in United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Breast Cancer, Colorectal Cancer
Trial of Patient Navigation-Activation
The University of Rochester, Department of Family Medicine, funded by the National Cancer Institute will train community health workers to guide patients through the cancer care system.
- Trial name
- NCT00496678
- Testing
- Navigation, Standard of Care
- Where
- United States
- Volunteers
- 900 people
- Sponsor
- University of Rochester
Breast Cancer
Role of 3D Tomography in Breast Cancer
The primary aim of this pilot study is to define the role of dedicated cone beam breast computed tomography in breast cancer imaging. This research is a prelude of a more comprehensive clinical trial that may follow.
- Trial name
- NCT01090687
- Testing
- computed tomography (CT scan)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Rochester
Alcohol Dependence, Depression
The MEADOW PROJECT (Mending the Effects of Alcohol and Depression on Women) and The Bridge Program (Connecting Recovery Treatment and Behavioral Health)
The aim of this study is to evaluate an interpersonally-focused intervention (Interpersonal Psychotherapy) for women with co-occurring alcohol dependence and depression.
- Trial name
- MEADOW/Bridge (NCT00851669)
- Testing
- Interpersonal Psychotherapy for Co-occurring Alcohol Dependence and Major Depression (IPT-ADMD), Treatment as Usual
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- University of Rochester
Surgical Site Infections
Eliminate Risk of Cardiac Surgical Site Events
The purpose of the study is to see if using 2% Chlorhexidine cloths will reduce surgical site infections in patients having elective cardiac surgery.
- Trial name
- ERASE (NCT01425697)
- Testing
- 2% Chlorhexidine Gluconate cloths, Standard of Care preoperative preparation.
- Where
- 4 sites in United States
- Volunteers
- 739 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Depression
Cognitive Behavioral Therapy for the Treatment of Depression-Related Insomnia
This study will determine the effectiveness of cognitive behavioral therapy (CBT) in treating insomnia symptoms that are secondary to depression.
- Trial name
- NCT00255905
- Testing
- Cognitive behavioral therapy (CBT) for insomnia, Clinician monitoring
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Rochester