Clinical trials: sponsored by University of Southern Denmark
Mild Traumatic Brain Injury, Concussion (Diagnosis)
Creatine Monohydrate for Mild Traumatic Brain Injury: a Randomised Controlled Pilot Study
Objectives: Approximately one-third of patients with concussion experience persistent symptoms that, in addition to causing serious discomfort, may lead to unemployment and other socioeconomic challenges.
- Trial name
- NCT06644131
- Testing
- Creatine Monohydrate
- Where
- Denmark
- Volunteers
- 34 people
- Sponsor
- University of Southern Denmark
Sleep, Heart Rate
A Digital Mindfulness Intervention to Improve Sleep Efficiency and Heart Rate Variability in Healthy Adults
This study tested whether a 10-day smartphone app-based mindfulness program can improve sleep and reduce physiological stress in healthy adults.
- Trial name
- NCT07469644
- Testing
- App-based mindfulness program (Headspace via Ōura app)
- Where
- Denmark
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Respiratory Tract Infections, Urinary Tract Infections
Intravenous Versus Oral Treatment of the Main Acute Infections
Patients admitted to the hospital with acute infections are often treated with intravenous (IV) antibiotics. Around 70% of these infections fall into three categories: respiratory tract infections, urinary tract infections, and…
- Conditions
- Respiratory Tract Infections, Urinary Tract Infections, Cellulitis
- Trial name
- NCT06715306
- Testing
- Oral treatment
- Where
- 7 sites in Denmark
- Volunteers
- 4,000 people
- Sponsor
- University of Southern Denmark
Hallucinations, Auditory
The ECHO Study: Compassion-focused Therapy for Young Voice Hearers and Their Caregivers
In this project, a 10-session treatment program was developed aimed at young people who experience voice hearing. The treatment has potential to easily be implemented in everyday clinical practice in Child and Adolescent…
- Trial name
- ECHO (NCT07314515)
- Testing
- ECHO Manualized CFT treatment for young voice heares
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- University of Southern Denmark
Ultrasound, Spinal Anaesthesia
Should Anaesthesiologists Be Taught to Perform Ultrasound-- Assisted Neuraxial Access in Spinal Anaesthesia?
Neuraxial blockade is commonly performed using a manual palpation technique, but the procedure can be challenging, particularly in patients with high body mass index, pregnancy, or spinal deformities.
- Conditions
- Ultrasound, Spinal Anaesthesia, Simulation Based Medical Education
- Trial name
- NCT07426679
- Testing
- Ultrasound-assisted spinal anaesthesia, Control group
- Where
- 2 sites in Denmark
- Volunteers
- 40 people
- Sponsor
- University of Southern Denmark
Postpartum Depression (PPD)
Evaluating the Effectiveness of an Internet-based Therapy (iCARE) to Treat Symptoms of Postpartum Depression
Postpartum depression (PPD) is a common and serious condition affecting 9.5% of women in high-income countries, and around 8% in Denmark.
- Trial name
- iCARE (NCT07384273)
- Testing
- Internet-based therapy (iCARE) and treatment as usual, Treatment as usual (TAU)
- Where
- Denmark
- Volunteers
- 352 people
- Sponsor
- University of Southern Denmark
Alcohol Use Disorder (AUD)
Online Interventions to Prevent Alcohol Use Disorders
Background: Internet-based interventions can improve access to non-treatment-seeking populations, preventing the onset or progression of alcohol use disorder (AUD).
- Trial name
- NCT07373405
- Testing
- Internet-Based Brief Alcohol Intervention, Unguided Internet-Based Cognitive Behavioral Therapy, Guided Internet-Based Cognitive Behavioral Therapy
- Volunteers
- 3,519 people
- Sponsor
- University of Southern Denmark
Heart Disease, Mental Health Outcomes
The Feasibility of an Intervention Targeting Sources of Meaning in Cardiac Rehabilitation
Being diagnosed with heart disease can be a life-changing experience, often sparking existential questions and concerns about meaning in life.
- Conditions
- Heart Disease, Mental Health Outcomes, Rehabilitation
- Trial name
- NCT07262580
- Testing
- Conversation on Sources of Meaning in life with heart disease, Group based session on Sources of Meaning in life with heart disease, Dyadic Conversation on Sources of Meaning in Life with heart disease
- Where
- 2 sites in Denmark
- Volunteers
- 80 people
- Sponsor
- University of Southern Denmark
Inflammatory Bowel Diseases, Ulcerative Colitis
Effects of Gluten Free Diet in Ulcerative Colitis
The goal is to evaluate gastrointestinal symptoms and fatigue levels during a period of eating gluten free compared to a period of high gluten consumption in individuals with confirmed Ulcerative Colitis, and to identify clinical…
- Trial name
- NCT06249763
- Testing
- High gluten diet, Gluten free diet
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- University of Southern Denmark
Pregnancy, Mother
A Feasibility Study of AMOR; ADHD, Mothers Online Resources
The primary aim of this study is to investigate the feasibility of the program AMOR for pregnant women and new mothers with Attention Deficit Hyperactivity Disorder (ADHD), by examining adherence, credibility, treatment…
- Conditions
- Pregnancy, Mother, Women, Attention Deficit Disorder With Hyperactivity
- Trial name
- AMOR (NCT06679010)
- Testing
- Online group counseling
- Where
- Denmark
- Volunteers
- 31 people
- Sponsor
- University of Southern Denmark
Overweight, Childhood, Obesity in Children
The Bloom Study - a Safe and Healthy Start in Life
The aim of the Bloom Study is to promote healthy weight development among infants through a home-based health promoting intervention implemented in the Danish setting of community health nurses.
- Trial name
- NCT06705400
- Testing
- Multi-behavioural
- Where
- Denmark
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Spinal Cord Injury (SCI)
Interdisciplinary Value-based Cognitive Behavioral Treatment for People With Traumatic Spinal Cord Injury
The goal of this clinical trial is to address the critical need for effective interventions by developing and testing an interdisciplinary values-based cognitive behavioral therapy (V-CBT) program for individuals with spinal cord…
- Trial name
- VALIANT (NCT06599632)
- Testing
- Values-based Cognitive Behavioral Therapy (V-CBT)
- Where
- Denmark
- Volunteers
- 6 people
- Sponsor
- University of Southern Denmark
Type2 Diabetes, Gestational Diabetes
Metabolic Risk and Life Style Factors in Women With Previous Gestational Diabetes Mellitus (GDM)
Women with previous Gestational Diabetes Mellitus (GDM) are characterized by several metabolic abnormalities i.e. insulin resistance, beta-cell dysfunction and increased risk of later Diabetes Mellitus (DM).
- Conditions
- Type2 Diabetes, Gestational Diabetes, Life Style
- Trial name
- NCT03050645
- Where
- Denmark
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Time Usage of ED Physicians
Physicians Work Distribution in a Danish Emergency Department
physicians in the Emergency Department spend their time on interviewing and examining patients, file documentation, communication with colleagues about the patients.
- Trial name
- NCT01722721
- Volunteers
- 9 people
- Sponsor
- University of Southern Denmark
Chemotherapy-induced Peripheral Neuropathy
Clinical Biomarker of Paclitaxel-induced Peripheral Neuropathy
Investigation of which patients treated with paclitaxel have an increased risk of developing peripheral neuropathy.
- Trial name
- NCT06430814
- Testing
- No intervention
- Where
- 3 sites in Denmark
- Volunteers
- 188 people
- Sponsor
- University of Southern Denmark
Diabetes type2
Digital Individualized and Collaborative Treatment of T2D in General Practice Based on Decision Aid
The purpose of this project is to improve life of patients with type 2 diabetes through an IT-supported lifestyle and treatment intervention.
- Trial name
- DICTA (NCT04880005)
- Testing
- Clinical decision support, Digital Lifestyle Coaching, Integration to Standard Electronic Health Record
- Where
- Denmark
- Volunteers
- 400 people
- Sponsor
- University of Southern Denmark
Respiratory Tract Infections
Point of Care Polymerase Chain Reaction (PCR) Diagnostics of Respiratory Tract Infections in General Practice
The present study will assess the effect and cost-effectiveness of the availability of point-of-care (POC) PCR testing, in respiratory tract infections (RTIs) in general practice, compared with usual care.
- Trial name
- NCT06120153
- Testing
- POC PCR-test device
- Where
- Denmark
- Volunteers
- 5,700 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Anesthesia; Adverse Effect, Breast Cancer
Nociception Level Monitor (NOL) During Guided Analgesic Delivery in Breast Surgeries
To assess if perioperative consumption of opioids can be optimized with the assistance of a Nociception Level (NOL) monitor in breast surgery patients receiving pectoral and parasternal nerve blocks as supplementation to general…
- Trial name
- NCT05546021
- Testing
- NOL monitor
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- University of Southern Denmark
Depression Anxiety Disorder
Assessment of an App-based Anxiety/Depression Program in a Population With Elevated Anxiety/Depression
Generalized anxiety disorder is a mental health disorder characterized by feelings of tension and worry with physical symptoms including increased blood pressure.
- Trial name
- NCT06434883
- Testing
- Anxiety/Depression Program, Waitlist
- Where
- United States
- Volunteers
- 168 people
- Sponsor
- University of Southern Denmark
Amputation, Blood Loss
Pneumatic Tourniquet Versus no Tourniquet in Transfemoral Amputation
Lower extremity amputation patients represent a frail group of patients with extensive comorbidity. The most common indication of amputation is ischemia, infection and concomitant ischemic pain due to underlying chronic disease…
- Trial name
- NCT05550623
- Testing
- Tourniquet
- Where
- Denmark
- Volunteers
- 124 people
- Sponsor
- University of Southern Denmark