Clinical trials: sponsored by University of Southern Denmark
Hirschsprung Disease
Scintigraphic Defecography for Evaluation of Functional Outcome in an Adult Hirschsprung Population
This study aims to investigate long term outcomes of surgical intervention for Hirschsprung's disease and to explore the relation between scintigraphic defecography, type of surgery performed and symptoms as evaluated by a…
- Trial name
- NCT04957667
- Where
- Denmark
- Volunteers
- 32 people
- Sponsor
- University of Southern Denmark
Covid19, Morbidity
BCG to Reduce Absenteeism Among Health Care Workers During the COVID-19 Pandemic
The COVID-19 pandemic challenges available hospital capacity. Strategies to protect health care workers (HCW) are desperately needed.
- Conditions
- Covid19, Morbidity, Absenteeism
- Trial name
- EDCTP (NCT04641858)
- Testing
- BCG-Denmark, Saline
- Where
- 2 sites in Guinea-Bissau, Mozambique
- Volunteers
- 668 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Preeclampsia, CAS
Preeclampsia and Contact Activation
Preeclampsia (PE) affects approximately 5% of all pregnancies with 2,500 cases registered annually in Denmark. PE is characterized by incomplete modelling of the spiral arteries of the uterus, hypertension, inflammation…
- Conditions
- Preeclampsia, CAS, Misfolding Disease, Protein
- Trial name
- NCT04825145
- Testing
- Pregnancy
- Where
- Denmark
- Volunteers
- 234 people
- Sponsor
- University of Southern Denmark
Adverse Drug Event, Colon Cancer
Implementation and Quality Assurance of DPYD-genotyping in Patients Treated With Fluoropyrimidines.
The purpose of this study is to examine the benefits of a clinical implementation of a DPYD-genotype test to patients starting treatment with fluoropyrimidines (Fluorouracil (5-FU), capecitabine, tegafur).
- Conditions
- Adverse Drug Event, Colon Cancer, Breast Cancer, Pancreas Cancer
- Trial name
- NCT05266300
- Testing
- DPYD genotype
- Where
- Denmark
- Volunteers
- 722 people
- Sponsor
- University of Southern Denmark
Pyelonephritis Acute
Diagnostic Imaging of Acute Pyelonephritis
Acute pyelonephritis is important to recognize and treat quickly. Today the diagnosis is primarily clinical and often challenging. Sometimes acute pyelonephritis is complicated by obstruction leading to hydronephrosis.
- Trial name
- NCT04651244
- Testing
- MRI, Ultrasound performed by a radiologist, Point of care ultrasound
- Where
- Denmark
- Volunteers
- 19 people
- Sponsor
- University of Southern Denmark
Pneumonia
Clinical Characteristics of Acutely Hospitalized Adults With Community-acquired- Pneumonia
There is no gold standard when diagnosing of pneumonia. The variability of clinical signs and symptoms make it difficult to distinguish pneumonia from other causes of respiratory conditions.
- Trial name
- NCT04681963
- Testing
- Clinical Assessment within 4 hours of admission
- Where
- Denmark
- Volunteers
- 966 people
- Sponsor
- University of Southern Denmark
Acute Pyelonephritis
Accuracy of Infection Biomarkers in the Investigation of Patients With Suspected Acute Pyelonephritis
The aim of this study is to investigate the diagnostic and prognostic value of C-reactive protein (CRP), serum procalcitonin (PCT) and soluble urokinase plasminogen activator receptor (suPAR) in the initial investigation of…
- Trial name
- NCT04686318
- Testing
- Biomarkers for acute pyelonephritis
- Where
- Denmark
- Volunteers
- 229 people
- Sponsor
- University of Southern Denmark
Respiratory Tract Infections
The Value of Ultralow Dosis CT and Ultrasound in the Diagnosing of Pneumonia in the Emergency Department
Pneumonia is one of the most common infections in the emergency department (ED). Nevertheless, the current diagnostic tools are often slow and inaccurate.
- Trial name
- NCT04645030
- Testing
- Ultra low-dose computer thermography, lung ultrasound
- Where
- Denmark
- Volunteers
- 411 people
- Sponsor
- University of Southern Denmark
Community-acquired Pneumonia
Accuracy of Lung Injury Biomarkers in the Initial Investigation of Patients With Suspected Pneumonia
The aim of this study is to investigate the diagnostic and prognostic value of surfactant protein D, Krebs von den Lungen (KL-6), and Chitinase-3-like protein 1 (YKL-40) in the initial investigation of patients hospitalized with…
- Trial name
- NCT04686331
- Testing
- Biomarkers for pneumonia
- Where
- Denmark
- Volunteers
- 411 people
- Sponsor
- University of Southern Denmark
Acute Infection
Diagnostic Accuracy of Urine Flow Cytometry in Excluding Bacteruria
A more rapid test for bacteriuria is desired. This will exclude the patients not having bacteriuria, which will contribute to a more rapid and accurate diagnosis of infectious diseases.
- Trial name
- NCT04686292
- Testing
- urine flow cytometry
- Where
- Denmark
- Volunteers
- 966 people
- Sponsor
- University of Southern Denmark
Acute Pyelonephritis
Clinical Characteristics of Acutely Hospitalized Adults With Acute Pyelonephritis
Acute pyelonephritis is an acute infection. Today the diagnosis is made primarily on the basis of unspecific clinical symptoms with flank tenderness combined with as a key clue.
- Trial name
- NCT04667195
- Testing
- Clinical assessment
- Where
- Denmark
- Volunteers
- 966 people
- Sponsor
- University of Southern Denmark
Pneumonia, Bacterial
The Effect of a Point-of-care Sputum Specimen Assay at the Emergency Department for Patients Suspected of Pneumonia
Antibiotic resistance has been identified by the WHO as one of the biggest threats to the health of the world population. In Denmark, there has been an increasing focus on optimizing antibiotic consumption in recent years, but…
- Trial name
- NCT04651712
- Testing
- POC-PCR
- Where
- Denmark
- Volunteers
- 290 people
- Sponsor
- University of Southern Denmark
Infection
Infection With Unknown Origin in the Emergency Department
Patients suspected with infection is one of the major groups, who are admitted to the Danish Emergency Departments (ED). Currently, there is no overall description of the distribution of these infections.
- Trial name
- NCT04661085
- Testing
- Broader Medical history and clinical tests
- Where
- Denmark
- Volunteers
- 966 people
- Sponsor
- University of Southern Denmark
Pneumonia, Bacterial
Diagnostic Accuracy of Infection Biomarkers in the Initial Investigation of Patients With Suspected Pneumonia
The aim of this study is to investigate the diagnostic and prognostic value of C-reactive protein (CRP), serum procalcitonin (PCT) and soluble urokinase plasminogen activator receptor (suPAR) in the initial investigation of…
- Trial name
- NCT04652167
- Testing
- PCT, suPAR, Standard care
- Where
- Denmark
- Volunteers
- 411 people
- Sponsor
- University of Southern Denmark
Response, Non-response
Use of Animations Movies to Increase Response in a National Health Survey
The aim of this study is to examine the potential for animation movies to improve response rates and sample composition in an embedded randomized controlled trial in the Danish National Health Survey 2021.
- Trial name
- NCT05520242
- Testing
- Use of small animation movies to increase response in a national health survey
- Where
- Denmark
- Volunteers
- 201,200 people
- Sponsor
- University of Southern Denmark
Ergonomics
Using an Ergonomic Chinrest With or Without Shoulder Rest During Violin Playing: a Feasibility Study
A one-arm feasibility study was conducted to test if violinists would accept to play with an identified ergonomic chinrest (EC) with the brand name Kréddle every day for two weeks.
- Trial name
- NCT05509465
- Testing
- Ergonomic chinrest, Ergonomic chinrest used with a low Super Kun shoulder rest
- Where
- Denmark
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Hypermobility Syndrome Shoulder, Shoulder Pain Chronic
Shoulder Exercises in Hypermobile Patients With Shoulder Symptoms
Hypermobility Spectrum Disorder (HSD) is a recent diagnosis that covers generalised joint hypermobility with one or more secondary symptomatic musculoskeletal manifestations.
- Conditions
- Hypermobility Syndrome Shoulder, Shoulder Pain Chronic, Shoulder Luxation
- Trial name
- NCT03869307
- Testing
- Exercise
- Where
- 3 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- University of Southern Denmark
Healthy Volunteers, Drug-drug Interaction
The Effect of Dicloxacillin on Oral Absorption of Drugs
Worldwide there is an increase in antibiotic resistance which may have fatal long-term consequences. This is due to extensive use and sometimes misuse of antibiotics in the treatment of harmless infections.
- Trial name
- NCT05073627
- Testing
- Dicloxacillin
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Hypoglycemia Non-Diabetic, Gastric Bypass Status Complicating Pregnancy, Birth, or Puerperium
Bariatric Surgery and Consequences for Mother and Baby in Pregnancy
Background Roux-en-Y gastric bypass (RYGB) is a well-established treatment of obesity, most often performed in women during their reproductive years. Adverse events related to RYGB include hypoglycemia.
- Trial name
- BAMBI (NCT03713060)
- Testing
- Mixed meal test
- Where
- 2 sites in Denmark
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Adherence, Sports Injury Prevention Exercises, Athletic Injuries
Injury Prevention in Danish Youth Handball
The primary aim of this hybrid-effectiveness-implementation cluster randomised study is to investigate if a supported implementation of an injury prevention exercise program (Happy program) involving a train-the-trainer workshop…
- Trial name
- NCT05294237
- Testing
- Happy program, Support
- Where
- Denmark
- Volunteers
- 950 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark