Clinical trials: sponsored by University of Toronto
Healthy
The Impact of Protein Intake on Protein Metabolism During Intensified Training
Protein requirements in individuals who participate in endurance-based exercise training have been suggested to be greater than the current recommended dietary allowance (RDA).
- Trial name
- NCT02801344
- Testing
- Normal, Moderate, High
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Healthy
Protein Requirements in Resistance Trained Females
In this study, the investigators will use the minimally invasive indicator amino acid oxidation (IAAO) technique to determine protein requirements in weight-trained males.
- Trial name
- NCT03397043
- Testing
- Protein intake (dose)
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Healthy
Protein Requirements for Active Adolescent Males (IAAO-AM)
Protein requirements in active individuals have been suggested to be greater than the current recommended dietary allowance (RDA).
- Trial name
- NCT02859181
- Testing
- Amino Acid Intake
- Where
- Canada
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Postpartum Depression
Mobile Phone Based Peer Support to Prevent Postpartum Depression Among Adolescent Mothers
This pilot study will evaluate the feasibility and acceptability of a mobile phone based peer support intervention among adolescent mothers.
- Trial name
- NCT02818075
- Testing
- Mobile Phone Based Peer Support, Usual Care
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Protein/Amino Acid Metabolism, Indicator Amino Acid Oxidation Method
Influence of Habitual Protein Intake on AA Tracer Oxidation
Protein is an essential nutrient that one's diet to maintain important bodily functions and to recover from exercise. Currently, the Indicator Amino Acid Oxidation method (IAAO) has been used to determine protein requirements in…
- Trial name
- HPI (NCT03845569)
- Testing
- Dietary protein intake reduction, Three day Controlled Diet
- Where
- Canada
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Cataract Extraction, Fasting
Preoperative Fasting for Ambulatory Cataract Surgery: The PRACTICE Study
The current standard for cataract surgery is phacoemulsification with intraocular lens (IOL) implantation. In this procedure, topical anesthesia has become favoured over local anesthetic blocks due to potential serious…
- Conditions
- Cataract Extraction, Fasting, Aspiration Pneumonitis
- Trial name
- PRACTICE (NCT03828500)
- Testing
- Assistant-encouraged fasting up to ASA/CAS guideline limits
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- University of Toronto
Major Depressive Disorder, Recurrent, in Remission, Depressive Symptoms
Reducing Residual Depressive Symptoms With Web-based Mindful Mood Balance
Many patients report residual depressive symptoms despite seemingly successful treatment. With the investigators' previous funding, we developed - Mindful Mood Balance - an online treatment that targets RDS by teaching specific…
- Trial name
- NCT02190968
- Testing
- Usual Depression Care, Mindful Mood Balance
- Where
- United States
- Volunteers
- 460 people
- Sponsor
- University of Toronto
Carbohydrate Intolerance
Effect of Genetic Variation in Starch-digesting Enzymes on Digestibility and Glycemic Index of Cold and Hot Rice
This study evaluates the effect of different methods of preparation (cooked and consumed hot vs cooked, cooled overnight and consumed cold) and variation in the activity of salivary amylase on the glycemic index and carbohydrate…
- Trial name
- NCT03667963
- Testing
- Glucose, Glucose plus lactulose, Hot Rice
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Stress, Psychological
Effects of a Mindfulness Meditation App on Subjective Well-Being in Undergraduate University Students
Mindfulness training includes a variety of contemplative practices aimed at promoting intentional awareness of experience, coupled with attitudes of non-judgment and curiosity.
- Trial name
- NCT03783793
- Testing
- Mindfulness Training App, Cognitive Training With 2048
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Cardiovascular Risk Factor, Cardiovascular Diseases
Umbrella Review of the DASH Dietary Pattern and Cardiometabolic Risk
The European Association for the Study of Diabetes (EASD) guidelines have not made any specific recommendations regarding the Dietary Approaches to Stop Hypertension (DASH) diet, a dietary pattern that emphasizes fruits and…
- Conditions
- Cardiovascular Risk Factor, Cardiovascular Diseases, Coronary Heart Disease, Stroke
- Trial name
- NCT03542370
- Testing
- DASH dietary pattern
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- University of Toronto
DALK Corneal Transplant, Keratoconus
Comparison Between Standard Deep Anterior Lamellar Keratoplasty (S-DALK) and Intralase Enabled Deep Anterior Lamellar Keratoplaty (IE-DALK)
A prospective comparison between standard deep anterior lamellar keratoplasty (S-DALK) performed manually using a blade (trephine) and femtosecond laser-enabled deep anterior lamellar keratoplasty (IE DALK), where incisions are…
- Conditions
- DALK Corneal Transplant, Keratoconus, Scar
- Trial name
- NCT03732599
- Testing
- Standard Deep Anterior Keratoplasty (S-DALK), IE-DALK (femtosecond)
- Volunteers
- 100 people
- Sponsor
- University of Toronto
Ultrasound, Local Anesthetic
Ultrasound-guided Inferior Alveolar Nerve Block Study
The primary objective is to compare the success of the inferior alveolar nerve block using ultrasound versus a traditional landmarking technique (which historically has an approximate failure rate as high as 33.8%).
- Trial name
- NCT03748329
- Testing
- Ultrasound
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Hyperlipidemia, Cardiovascular Diseases
Effects of a Long Term Dietary Portfolio and of Sequential Removal of Food Components From the Diet
The purpose of this study is to evaluate the long term effectiveness of the dietary portfolio, consisting of viscous fibers, soy products, nuts and plant sterols, as well as the effects of removing single food components from the…
- Conditions
- Hyperlipidemia, Cardiovascular Diseases, Hypercholesterolemia
- Trial name
- NCT00438893
- Testing
- Dietary portfolio of cholesterol-lowering foods
- Where
- Canada
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Hyperlipidemia, Cardiovascular Disease
Portfolio 5 - Multicentre Dietary Advice on Serum Lipids in Hyperlipidemia
The purpose of this trial is to re-evaluate the potential role of diet in modulating cardiovascular risk factors. If potent lipid-lowering effects through novel dietary interventions can be demonstrated, then diet may again be…
- Trial name
- NCT00438425
- Testing
- Dietary Portfolio - Intensive, Dietary Portfolio - Routine, Control (low saturated fat therapeutic diet)
- Where
- 5 sites in Canada
- Volunteers
- 351 people
- Sponsor
- University of Toronto
CHD - Coronary Heart Disease, CVD - Cerebrovascular Disease
Meta-analysis of Fruit and Vegetable Sources and Cardiovascular Outcomes
Fruit and vegetables are a cornerstone of healthy dietary patterns and dietary guidelines worldwide. The supporting evidence, however, is largely derived from observational studies of protective associations with cardiovascular…
- Conditions
- CHD - Coronary Heart Disease, CVD - Cerebrovascular Disease, Stroke
- Trial name
- NCT03394339
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- University of Toronto
Diet Modification, Cardiovascular Diseases
The Efficacy of Front-of-package Labelling Schemes: an Experimental Study
This is an online study that aims to test the effectiveness of Interpretative Nutrition Rating Systems (INRS) such as the Health Star Rating System (HSR or Star System), traffic light system and warning labels (high sodium…
- Conditions
- Diet Modification, Cardiovascular Diseases, Nutrition
- Trial name
- NCT03290118
- Testing
- Nutrition Rating System - Traffic Light, Nutrition Rating System - Health Star, Nutrition Rating System - Warning Label
- Where
- Canada
- Volunteers
- 2,008 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Healthy
Protein Requirements in Resistance-trained Males
In this study, the investigators will use the minimally invasive indicator amino acid oxidation (IAAO) technique to determine protein requirements in resistance-trained males.
- Trial name
- NCT03696264
- Testing
- Amino acid intake
- Where
- Canada
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Hypertension, Type 2 Diabetes
Effect of Managing Problematic Eating Behaviours With Dietary Management on Chronic Disease Self-management
Dietary management is an integral aspect of self care for many chronic diseases. Craving Change™ is a standard program already offered at many Family Health Teams (FHT) to patients interested in being more mindful of their food…
- Trial name
- NCT01804881
- Testing
- Lifestyle counseling
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Toronto Practice Based Research Network
Cardiovascular Diseases, Coronary Heart Disease
Meta-analysis of Vegetarian Diets and Incident Cardiovascular Outcomes
Vegetarian and vegan diets have been shown to reduce cardiometabolic risk factors for chronic diseases, such as cardiovascular disease and diabetes, and have been associated with decreased risk of these chronic diseases.
- Conditions
- Cardiovascular Diseases, Coronary Heart Disease, Stroke, Mortality
- Trial name
- NCT03610828
- Testing
- Vegetarian or Vegan Diets
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Continuous Rhythmic Auditory Stimulation, Intermittent Rhythmic Auditory Stimulation
Long-term Training Effects of Rhythmic Auditory Stimulation on Gait in Patients With Parkinson's Disease
Falls are common among patients with Parkinson's Disease (PD) and are the biggest contributors to loss of independent living, long-term institutionalization, and increased mortality.
- Trial name
- NCT03316365
- Testing
- Rhythmic Auditory Stimulation (RAS)
- Volunteers
- 60 people
- Sponsor
- University of Toronto