Clinical trials: sponsored by University of Toronto
Healthy, Glucose Metabolism
Protein Concentrations in Yogurt and Satiety, Food Intake and Glycemia in Healthy Men
This study compared the effects of dairy products, including milk and yogurt, with different amounts of proteins on responses of appetite, glucose and insulin and on food intake at a meal served 120 minutes later in healthy adult…
- Trial name
- NCT01673321
- Testing
- Dietary intervention
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Attention-Deficit Hyperactivity Disorder
Working Memory Training in ADHD (The Engage Study)
The overall objective of the current study is to determine whether computerized Working Memory (WM) training will enhance WM capacity in college students with Attention Deficit Hyperactivity Disorder (ADHD).
- Trial name
- NCT01657721
- Testing
- Cogmed Working Memory Training Program
- Where
- Canada
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Pain
The Effect of an Individualized Education Intervention on Pain Following Inguinal Hernia Repair Surgery
Pain after inguinal hernia repair surgery is common with more than 50% of patients reporting moderate to severe acute pain following surgery.
- Trial name
- HREI (NCT01063790)
- Testing
- Individualized Education
- Where
- Canada
- Volunteers
- 82 people
- Sponsor
- University of Toronto
Vitamin D Status
The Impact of Vitamin D Status on in Vitro Fertilization (IVF) Outcomes
Infertility is a common and psychologically devastating problem for 20% of Canadian couples. Approximately, 20% of infertile couples are diagnosed with unexplained infertility and left without an explanation for their inability…
- Trial name
- NCT01348594
- Where
- Canada
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Obesity, Overweight
The Effect of Eating Pulses for 8 Weeks on Satiety and Metabolic Syndrome Risk Factors in Overweight Individuals
In 2004, almost 60% of adult Canadians were overweight or obese. This is a serious health concern due to the burden of common health risks associated with being overweight and obese, including increased blood sugar, blood lipids…
- Trial name
- NCT00604448
- Testing
- Dietary advise, Diet enriched with a meal containing pulses
- Where
- Canada
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Obesity, Hyperglycemia
A Comparison of Beverages Consumed Within a Meal to Satiation on Meal-time Food Intake and Post-meal Appetite and Glycemic Response in Healthy Young Adults
The objective of the current study is to determine the effects of an ad libitum intake of 1% milk, fruit juice, regular cola, diet cola and water, as part of a pizza meal, on meal food intake, appetite and postprandial blood…
- Trial name
- NCT01595919
- Testing
- Nutritional Intervention
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Overweight, Obesity
Effect of Consuming Beans for One Month on Blood Lipids, Satiety, Intake Regulation and Body Weight
This project investigates the effect of regular consumption of commercially available processed white beans (5 cups per week) on food intake, body weight, blood pressure, satiety hormones and glycemic response over a 4-week…
- Conditions
- Overweight, Obesity, Metabolic Syndrome, Diabetes
- Trial name
- NCT00741923
- Testing
- navy beans added to regular diet
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- University of Toronto
Obesity, Type II Diabetes Mellitus
Yellow Pea Protein and Fibre and Short Term Food Intake
It is hypothesized that yellow pea protein and fiber will reduce short-term food intake, subjective appetite and glycemic response.
- Conditions
- Obesity, Type II Diabetes Mellitus, Metabolic Syndrome
- Trial name
- NCT01255085
- Testing
- yellow pea protein, yellow pea fiber, Control Tomato Soup
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Diabetes Prevention, Obesity Prevention
Isovolumetric and Isocaloric Preloads of Various Types of Milk on Food Intake, Subjective Appetite and Glycemic Response
The purpose of this protocol is to study the effects of fluid milk products on satiety, food intake, and glucose metabolism in healthy young men and women.
- Trial name
- NCT01025557
- Testing
- Dietary intervention
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Obesity, Type II Diabetes Mellitus
Yellow Pea Fractions and Short-term Food Intake, Subjective Appetite and Glycemic Response
It is hypothesized that yellow pea protein and fiber will reduce short-term food intake, subjective appetite and glycemic response.
- Conditions
- Obesity, Type II Diabetes Mellitus, Metabolic Syndrome
- Trial name
- NCT01242059
- Testing
- yellow pea protein, yellow pea fiber, Control
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Atrial Fibrillation, Diet Therapy
ALA and Prostate Cancer
The problem is the lack of data from randomized controlled trials to throw light on the ALA-prostate cancer issue. There is therefore a need to acquire evidence from a randomized controlled study to illustrate the effect of ALA…
- Conditions
- Atrial Fibrillation, Diet Therapy, Prostate Cancer
- Trial name
- NCT00309439
- Testing
- ALA-rich diet
- Sponsor
- University of Toronto
Herpes Simplex Type Two Infection, HIV Infections
Examining the Ability of Herpes Simplex Virus Type 2 (HSV2) Therapy to Reduce HIV Target Cell Numbers in the Cervix
Herpes simplex virus type 2 (HSV2), the most common cause of genital herpes, increases a woman's risk of HIV acquisition from 3-6 fold, perhaps because HSV2-infected women have increased numbers of HIV "target cells" (CD4 T cells…
- Trial name
- NCT00946556
- Testing
- Valacyclovir
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Toronto
The Focus is to Assess 25-hydroxyvitamin D Levels and Well-being
Vitamin D Fortified Cheese and Well-being in the Institutionalized Elderly
The investigators hypotheses is that the consumption of the investigators vitamin D fortified cheese will result in an increase in serum 25-hydroxy vitamin D levels in older institutionalized adults.
- Trial name
- NCT01555424
- Testing
- High dose, Reference dose
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Prostate Cancer
Vitamin D Effects on Prostate Pathology
There is much interest in understanding the role that vitamin D3 (cholecalciferol) plays in various cancers, and in the prognosis of various cancers once they are discovered.
- Trial name
- DProstate (NCT00741364)
- Testing
- vitamin D3 (cholecalciferol)
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- University of Toronto
Computer, Screening
Computer-assisted Psychosocial Risk Assessment (CaPRA) for Refugee Health and Settlement
The purpose of this study was to examine preliminary effect of Computer-assisted Psychosocial Risk Assessment tool (CaPRA) among Afghan refugees visiting medical professionals (family physicians or nurse practitioners) at a…
- Conditions
- Computer, Screening, Decision Support System, Primary Care
- Trial name
- CaPRA (NCT01427829)
- Testing
- Computer-assisted Psychosocial Risk Assessment (CaPRA)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Intraocular Pressure
The Response of Intraocular Pressure to Systemic Hypercapnia and Hyperoxia
The purpose of this study is to determine how intraocular pressure responds to changes in the levels of carbon dioxide or oxygen that a healthy individual inspires.
- Trial name
- NCT01325285
- Testing
- RespirAct
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Metabolic Syndrome
Pulses, Satiation, Food Intake and Blood Glucose
Pulses have the potential to be positioned as a food for body weight and metabolic control based on their composition, effects on rate of digestion and absorption of fat and carbohydrates, and effects on satiety.
- Trial name
- NCT01410851
- Testing
- dietary treatment
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Gestational Diabetes
The Effect of a Low Glycemic Index Diet on Blood Sugar Control in Women With Gestational Hyperglycemia
The purpose of the study is to see if a low glycemic index diet will reduce blood sugar levels in pregnant women with high blood sugar levels.
- Trial name
- NCT00314717
- Testing
- Control diet, Low GI diet
- Where
- Canada
- Volunteers
- 47 people
- Sponsor
- University of Toronto
Obesity, Diabetes
Fibre and Appetite Regulation Trial (FART)
High intake of cereal fibre has been shown to be associated with reduced weight gain and improved insulin sensitivity. We hypothesize these effects are due to the short chain fatty acids derived from the bacterial fermentation…
- Trial name
- NCT00247455
- Testing
- Low fibre breakfast cereal (puffed rice/cornflakes), High fibre cereal (All Bran/Bran Flakes)
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Ankle Injuries
Early Weightbearing and Mobilization Versus Non-Weightbearing and Mobilization in Unstable Ankle Fractures
The primary objective of the investigators randomized controlled trial is to determine if early protected weightbearing and ankle range of motion after surgical treatment (open reduction internal fixation - ORIF) for ankle…
- Trial name
- NCT01196338
- Testing
- Early weight-bearing and range of motion exercises, non-weight bearing, no range of motion
- Where
- 2 sites in Canada
- Volunteers
- 110 people
- Sponsor
- University of Toronto