Clinical trials: sponsored by University of Toronto
Cerebral Palsy
Investigating Best Practices for Children With Cerebral Palsy: A Pilot Study of Two Approaches
This project (CO-OP II) is the second in a series of three studies to validate a new treatment approach for children with cerebral palsy (CP).
- Trial name
- NCT00430131
- Testing
- Cognitive Orientation to Occupational Performance, Contemporary Treatment Approach
- Volunteers
- 18 people
- Sponsor
- University of Toronto
Coronary Artery Disease
Cardiac Home Education and Support Trial (CHEST): A Pilot Study
Coronary artery bypass graft (CABG) surgery is performed more frequently on individuals who are older and sicker than in previous years.
- Trial name
- NCT00275340
- Testing
- Peer Support
- Where
- Canada
- Volunteers
- 101 people
- Sponsor
- University of Toronto
Hyperlipidemia, Cardiovascular Diseases
The Influence of Soy Isoflavnoids on the Hypocholesterolemic Effects of Soy
Isoflavonoids, through their estrogen-like activity, are in part responsible for the cholesterol lowering properties of soy foods.
- Trial name
- NCT00877825
- Testing
- dairy food control diet and high- and low- isoflavone soyfood diets
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Toronto
Brain Injuries
Expressive Arts as a Social and Community Integration Tool for Youth Recovering From Brain Injury
This study utilizes a novel technique-expressive arts therapy-to facilitate social integration for youth recovering from acquired brain injury (ABI).
- Trial name
- NCT00434603
- Testing
- Expressive Arts--Theatre Skills Training Program
- Volunteers
- 8 people
- Sponsor
- University of Toronto
Hypercholesterolemia, Cardiovascular Disease
Barley Protein and CVD
The Question posed is: Does an barley protein concentrate have health benefits similar to those demonstrated for soy protein foods which would justify the use of the non-fiber components of barley as functional food ingredients?…
- Conditions
- Hypercholesterolemia, Cardiovascular Disease, Diet Therapy
- Trial name
- NCT00334308
- Testing
- Barley protein bread or control (casein) bread
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Hyperlipidemia, Cardiovascular Disease
The Effect of Altering Colonic Microflora After Fiber (FOS) Consumption
Our antibiotic studies indicated that cholesterol lowering was seen when fecal bifidobacterial counts were increased. Due to the dangers associated with prolonged antibiotic use we have been funded by the Heart and Stroke…
- Conditions
- Hyperlipidemia, Cardiovascular Disease, Diet Therapy
- Trial name
- NCT00516594
- Testing
- Diet with polyfructans and viscous fibers or soy protein
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Toronto
Iron Deficiency, Folic Acid Deficiency
Relative Bioavailability of Iron and Folic Acid in New Test Supplement
Deficiencies of iron and folic acid during pregnancy can lead to adverse outcomes for the fetus, thus supplements are recommended. Adherence to current tablet-based supplements is documented to be poor.
- Trial name
- NCT00789490
- Testing
- Daminaide 995 - SuppleFem Sprinkles, Materna
- Where
- Canada
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Vitamin D Deficiency, Low Bone Density
Nursing-Home Residents Given Bread Fortified With Vitamin D3
Background. For older adults, serum 25-hydroxyvitamin D (25(OH)D) higher than 75 nmol/L lowers fracture risk and attainment of this 25(OH)D target may require 125 mcg (5000 IU)/d of vitamin D3.
- Trial name
- NCT00789503
- Testing
- Bread fortified with vitamin D3 and calcium
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Emotional Pain
Effects of Acetaminophen on Hurt Feelings
The purpose of the study is to investigate whether ingestion of acetaminophen reduces the experience of hurt feelings.
- Trial name
- NCT00561288
- Testing
- acetaminophen, cornstarch
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Retinal Vein Occlusion, Retinal Vein Thrombosis
Atorvastatin for the Treatment of Retinal Vein Occlusion
The ATORVO study is designed to determine whether atorvastatin (Lipitor) can improve vision, when compared to placebo
- Conditions
- Retinal Vein Occlusion, Retinal Vein Thrombosis, Central Retinal Vein Occlusion, Branch Retinal Vein Occlusion
- Trial name
- ATORVO (NCT00517257)
- Testing
- Atorvastatin
- Where
- Canada
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Hypertension, Hypertension, Pregnancy-Induced
The Relaxation and Blood Pressure in Pregnancy (REBIP) Study
Over 10% of women have high blood pressure during their pregnancy which may affect their health or that of their baby. There are currently no methods to prevent most high blood pressure in pregnancy and some treatments are not…
- Conditions
- Hypertension, Hypertension, Pregnancy-Induced, Pre-Eclampsia
- Trial name
- NCT00303173
- Testing
- Guided Imagery
- Where
- 2 sites in Canada
- Volunteers
- 69 people
- Sponsor
- University of Toronto
Multiple Sclerosis
Safety Trial of High Dose Oral Vitamin D3 With Calcium in Multiple Sclerosis
Vitamin D likely plays a role in the geography of Multiple Sclerosis (MS), and patients at risk and with MS have relatively low Vitamin D levels compared to their normal counterparts.
- Trial name
- VitD4MS (NCT00644904)
- Testing
- Vitamin D3
- Where
- Canada
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Abdominal Obesity
Effect of Replacing HFCS With Sucromalt in Subjects With Raised Waist Circumference
Weight gain is linked to a high consumption of soft-drinks and other beverages sweetened with high fructose corn syrup. Being overweight increases risk for diabetes and heart disease.
- Trial name
- NCT00374218
- Testing
- High Fructose Corn Syrup, Sucromalt
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Heliobacter Pylori Infection
Effect of Helicobacter Pylori on the Availability of Vitamin E and C
This study argues that H.pylori infection, by increasing the production of reactive oxygen species, increases the utilization of dietary antioxidants(Vit E and Vit C) that serve in quenching the free radicals, thus decreasing…
- Trial name
- NCT00303160
- Testing
- vitamin C & E supplements
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Hyperlipidemia, Diet Therapy
Almond Dose Response Study.
To assess the effects of almonds on coronary heart disease (CHD) risk factors (serum lipids, measurements of oxidative stress and nitric oxide production) when added to the diets of subjects with high cholesterol.
- Conditions
- Hyperlipidemia, Diet Therapy, Cardiovascular Disease
- Trial name
- NCT00507520
- Testing
- Full dose almonds, Half dose almonds+half dose muffin, Full dose whole wheat muffin
- Where
- Canada
- Volunteers
- 27 people
- Sponsor
- University of Toronto
Trauma, Stress
The Effects of Stress on the Clinical Performance of Residents in Simulated Trauma Scenarios
Medical practice \& training are inherently stressful situations. However, the effects of stress on educational \& clinical performance are not well defined.
- Trial name
- NCT00485927
- Testing
- stress
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Toronto
Hyperlipidemia, Cardiovascular Diseases
The Effect of Strawberries in a Cholesterol-Lowering Dietary Portfolio
The purpose of this study is to determine whether addition of strawberries to a dietary portfolio of cholesterol-lowering foods will improve compliance and so increase the effectiveness of the dietary portfolio in lowering…
- Conditions
- Hyperlipidemia, Cardiovascular Diseases, Hypercholesterolemia
- Trial name
- NCT00345722
- Testing
- strawberry dietary intervention
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Computers, Handheld, Outcomes Assessment, Patient
Outcomes in the Palm of Your Hand: Improving the Quality and Continuity of Patient Care
This study evaluates the usability of personal digital assistants (PDAs) by nurses for collecting, utilizing and communicating patient health information, and the feasibility of using PDAs to increase nurses' access to and…
- Trial name
- NCT00314730
- Testing
- handheld Personal Digital Assistant (PDA)
- Where
- 3 sites in Canada
- Volunteers
- 400 people
- Sponsor
- University of Toronto
Atrial Fibrillation, Diet Therapy
Studies of the Prevention of Atrial Fibrillation by ALA
An alpha-linolenic acid (ALA) rich diet in the Lyon Heart Study reduced sudden cardiac deaths possibly by reducing cardiac arrhythmias and ventricular fibrillation (Lancet 1994).
- Trial name
- NCT00410839
- Testing
- ALA rich diet
- Where
- France
- Volunteers
- 130 people
- Sponsor
- University of Toronto
Glaucoma
Compliance and Administration Technique in Topical Drug Therapy of Glaucoma
Clinic-based evaluation of patients compliance with topical medications in the treatment of glaucoma. Also assessing effectiveness of delivery techniques among these patients.
- Trial name
- NCT00303121
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University of Toronto