Clinical trials: sponsored by University of Utah
Cancer, Risk Reduction Behavior
Broadening the Reach, Impact, and Delivery of Genetic Services
The purpose of this study is to compare the uptake of genetic testing among patients randomized with two different models of genetic services delivery (a patient-directed model and an enhanced standard of care model) and examine…
- Trial name
- BRIDGE (NCT03985852)
- Testing
- Patient Directed Standard of Care
- Where
- 2 sites in United States
- Volunteers
- 3,073 people
- Sponsor
- University of Utah
Alcohol Drinking, Opioid Use
Co-Use of Opioid Medications and Alcohol Prevention Study
Previous research, including that of this team, shows that a significant portion of those regularly using opioids-particularly filling opioids at community pharmacies-also are involved in the co-use of alcohol.
- Trial name
- COAPS (NCT05599672)
- Testing
- Alcohol-targeted Brief Intervention-Medication Therapy Management, Standard medication counseling
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- University of Utah
Thromboembolism
Low Molecular Weight Heparin or no Treatment Following Cesarean Delivery
The aim of this study is to evaluate the feasibility of randomizing individuals to low molecular weight heparin (enoxaparin) or no treatment following cesarean delivery.
- Trial name
- NCT06118957
- Testing
- Enoxaparin
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Utah
Post-Traumatic Stress Disorder in Children, Post-Traumatic Stress Disorder in Adolescence
Recovery After Stress Toolkit (RESET) Study
This study evaluates the use of web-based educational modules combined with telehealth delivered therapy for children with post-traumatic stress symptoms (PTSS) after receiving hospital based medical attention for an injury.
- Trial name
- ReSeT (NCT04838977)
- Testing
- RESET
- Where
- 3 sites in United States
- Volunteers
- 93 people
- Sponsor
- University of Utah
NIRS, Cardiac Surgery Associated - Acute Kidney Injury
A Comparison of Renal vs Limb NIRS for Predicting Cardiac Surgery Associated Acute Kidney Injury
Acute kidney injury (AKI) is a complication of cardiac surgery that can affect outcome. Near Infrared Spectroscopy (NIRS) is a technology that uses light to determine how well oxygenated tissues are.
- Conditions
- NIRS, Cardiac Surgery Associated - Acute Kidney Injury, Cardiac Surgery Requiring Cardiopulmonary Bypass, AKI - Acute Kidney Injury
- Trial name
- NCT06705855
- Testing
- NIRS sensor placement
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Utah
Financial Burden, Health Behavior
Economic Empowerment and Health Promotion of Uganda Grandmother-caregivers.
Background: There are an estimated 163 million children worldwide who are under the care of their grandparents or other relatives.
- Conditions
- Financial Burden, Health Behavior, Social Support
- Trial name
- BAJJAJJA (NCT07011264)
- Testing
- The BAJJAJJA intervention
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Utah
Physical Therapy
Real-Time Biofeedback on Partial Weightbearing Training
The purpose of this study is to investigate the effectiveness of a biofeedback device (Loadsol) in training healthy subjects to comply with partial weightbearing, and to compare its outcomes with the standard of care training.
- Trial name
- NCT06368778
- Testing
- Verbal Advice, Bathroom Scale, Loadsol Biofeedback
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Utah
Breast Cancer
Community Services Navigation to Advance Health Equity in Breast Cancer Screening
The goal of this study is to evaluate if adding community services navigation to the standard referral process for social needs is an effective and scalable strategy for addressing disparities in follow-up to abnormal breast…
- Trial name
- B-SINCERE (NCT06305312)
- Testing
- Community Service Navigation, Usual Care
- Where
- United States
- Volunteers
- 1,450 people
- Sponsor
- University of Utah
Prostate Cancer, Metastatic Prostate Cancer
Impact of Multimodal Telerehabilitation in Rural Patients With Metastatic Prostate Cancer
People with prostate cancer may have a decreased quality of life due to the cancer itself and due to a lifesaving cancer treatment.
- Conditions
- Prostate Cancer, Metastatic Prostate Cancer, Androgen Deprivation Therapy
- Trial name
- NCT07032584
- Testing
- Telerehabilitation Intervention
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of Utah
Bladder Cancer, Cystectomy
A Home-based Lifestyle Intervention for Optimizing Surgical Outcomes Among Urinary Bladder Cancer Patients
The purpose of this study is to test a randomized, controlled diet and physical activity intervention designed to be simple and address barriers to participation in lifestyle intervention among 16 urinary bladder cancer patients.
- Conditions
- Bladder Cancer, Cystectomy, Chemotherapy
- Trial name
- BOOST (NCT06002269)
- Testing
- Dietary and Exercise Intervention
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Utah
Autoimmune Encephalitis, Encephalitis
The ExTINGUISH Trial of Inebilizumab in NMDAR Encephalitis
Determine the difference in the modified Rankin score at 16 weeks in participants with anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis treated with "first-line" immunomodulatory therapies provided as standard-of-care, and…
- Trial name
- ExTINGUISH (NCT04372615)
- Testing
- Inebilizumab
- Where
- 39 sites in United States, Netherlands and 1 more
- Volunteers
- 116 people
- Sponsor
- University of Utah
Pain
Brief Mindfulness for Foot and Ankle Pain
This is a single-site, four-arm, parallel-group randomized clinical trial (RCT). The clinical effects of three different formats of a very brief (i.e., 3 minute), audio-recorded mindfulness intervention for foot and ankle…
- Trial name
- NCT05939843
- Testing
- Pain Coping Information, Mindfulness Practice (alone), Mindfulness Introduction + Mindfulness Practice
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Utah
Pain, Anxiety
Mindfulness Intervention in Orthopedic Trauma Patients
This project a single-site 3-arm parallel group randomized clinical trial conducted at a tertiary level 1 trauma center among patients undergoing operative fixation of a lower extremity fracture.
- Trial name
- NCT05634278
- Testing
- Preoperative mindfulness, Postoperative mindfulness, Mind wandering
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- University of Utah
Pain, Anxiety State
App Delivered Brief Mindfulness Intervention for Surgical Patients
This will be a single-site, five-arm, parallel group randomized control trial involving patients undergoing knee or hip replacement surgery.
- Conditions
- Pain, Anxiety State, Depressive State
- Trial name
- NCT05433389
- Testing
- Breath Counting, Body Scan, Mindful Breathing
- Where
- United States
- Volunteers
- 823 people
- Sponsor
- University of Utah
Perceptual Disorders, Stroke
Neurobiomarker for Prism Adaptation Treatment Response
Preliminary data will be collected about which individuals with spatial neglect from right hemisphere stroke (aiming vs perceptual neglect) improve with Prism Adaptation Training and if there is a particular pattern of damage in…
- Conditions
- Perceptual Disorders, Stroke, Biomarker
- Trial name
- NCT04966000
- Testing
- Prism Adaptation Therapy
- Where
- United States
- Sponsor
- University of Utah
Colorectal Cancer
ColoCare Study - Colorectal Cancer Cohort
ColoCare is an international prospective cohort study of stage I-IV colorectal cancer patients (ICD-10 C18-C20).
- Trial name
- NCT02328677
- Where
- 7 sites in United States, Germany
- Volunteers
- 5,000 people
- Sponsor
- University of Utah
Leiomyosarcoma
Beliefs, Attitudes, and Response to Genetic Testing in SarcomaPatients
Genomic research has shown that a portion of leiomyosarcomas can be attributed to an underlying cancer predisposition syndrome. However, the optimal approach for incorporating germline testing into the care of these patients.
- Trial name
- NCT06875700
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Utah
Spinal Cord Injury, Acute, Neurogenic Bladder
Sacral Nerve Stimulation in Improving Bladder Function After Acute Traumatic Spinal Cord Injury
The purpose of this study is to see what effects sacral neuromodulation has on bladder function and quality of life in patients with acute spinal cord injury.
- Conditions
- Spinal Cord Injury, Acute, Neurogenic Bladder, Incontinence, Urinary Tract Infections
- Trial name
- NCT03083366
- Testing
- PrimeAdvanced Surescan 97702 Neurostimulator - Medtronic (Minneapolis, MN)
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- University of Utah
Chronic Lymphocytic Leukemia
RP-3500 and Olaparib in DNA Damage Repair Pathway Deficient Relapsed/Refractory Chronic Lymphocytic Leukemia
This is an open-label, multicenter, phase Ib/II study of the combination of RP-3500 and olaparib in Relapsed/Refractory Chronic Lymphocytic Leukemia (R/R CLL) patients with DDR deficiencies.
- Trial name
- CORONADO CLL (NCT05405309)
- Testing
- RP-3500, Olaparib
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Utah
Tics, Tourette Disorder
Investigating Changes in Premonitory Urges During Habit Reversal Training for Tics
The primary aim of this study is to learn more about premonitory urges (PU) when using Habit Reversal Training (HRT) to treat tics.
- Conditions
- Tics, Tourette Disorder, Tourette Syndrome in Children, Tourette Syndrome in Adolescence
- Trial name
- NCT06825520
- Testing
- Habit Reversal Training
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Utah