Clinical trials: sponsored by University of Utah
Patient Lying, Privacy Statements
Patient Doctor Lies
Accurate patient information disclosure is critical to provide optimal treatment. Methods that can detect and then increase the truthfulness of information are relatively unknown.
- Conditions
- Patient Lying, Privacy Statements, Risk Statements, Benefit Statements
- Trial name
- NCT04803448
- Testing
- Benefit statement, Risk Statement, Privacy Statement
- Where
- United States
- Volunteers
- 619 people, healthy volunteers welcome
- Sponsor
- University of Utah
Sleep
Randomized Experiment of Sleep Technology
Short sleep duration is highly prevalent and linked to negative mental and physical health consequences, including increased cardiovascular disease risk [1].
- Trial name
- NCT04246424
- Testing
- Fibit + Coaching, Coaching, Fitbit
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Utah
Low Back Pain, Sciatica
Management Strategies for Patients With Low Back Pain and Sciatica
Low back pain and sciatica is a common condition resulting in high costs and disability for society and affected individuals. Presently there is a lack of evidence for what treatments may help this condition early in the course…
- Conditions
- Low Back Pain, Sciatica, Physical Therapy
- Trial name
- NCT02391350
- Testing
- Education and re-assurance, Physical Therapy
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- University of Utah
Bone Metastases, Breast Cancer
Merestinib on Bone Metastases in Subjects With Breast Cancer
This is an open label, pharmacodynamics, intrapatient dose escalation phase 1B study.
- Trial name
- NCT03292536
- Testing
- Merestinib
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Utah
Irritable Bowel Syndrome
The Effect of Long-Acting Mesalamine on Post-Infective Irritable Bowel Syndrome- A Pilot Study
The purpose of this study is to evaluate the effects of long acting mesalamine (Lialda) in patients with Post-Infective Irritable Bowel Syndrome (PI-IBS).
- Trial name
- Mesalamine (NCT01412372)
- Testing
- Mesalamine
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- University of Utah
Respiratory Failure, COVID-19
Prone Positioning in Awake Patients With COVID-19 Requiring Hospitalization
Acute respiratory distress syndrome (ARDS) is a major complication among patients with severe disease. In a report of 138 patients with COVID-19, 20% developed ARDS at a median of 8 days after the onset of symptoms, with 12.3% of…
- Trial name
- PAPR (NCT04368000)
- Testing
- Intermittent prone positioning instructions, Usual care positioning with no instructions
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Utah
Breast Cancer
Understanding and Addressing Patient and Provider Preferences Around Discussions of Cost of Breast Cancer Care
The investigators hypothesize that many cancer patients desire discussions of cost as part of their care, but that preferences for having cost discussions with their physicians vary.
- Trial name
- NCT03780491
- Testing
- Cost Discussion
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Utah
Myofascial Pain
TPI Medication Comparison - Ketorolac, Lidocaine, or Dexamethasone
Hypothesis The main hypothesis of this study is that anti-inflammatory medications (ketorolac or dexamethasone) will provide longer-lasting and greater pain relief than just lidocaine in trigger point injections where a local…
- Trial name
- NCT03028012
- Testing
- Ketorolac, Lidocaine, Dexamethasone
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Utah
Child Abuse, Primary Health Care
Collaborative Care for Infants at Risk
This study evaluates the feasibility, acceptability, and impact of a collaborative care practice for infants investigated by state Child Protective Services (CPS) for suspected maltreatment.
- Conditions
- Child Abuse, Primary Health Care, Child Welfare
- Trial name
- CCIR (NCT03199326)
- Testing
- Collaborative Care
- Where
- United States
- Volunteers
- 468 people
- Sponsor
- University of Utah
Opioid-use Disorder, Pregnancy Related
Perinatal Care and Medication Assisted Treatment: Carbon/Emery Counties
The purpose of this study is to enhance perinatal opioid use disorder (OUD) treatment in a rural setting by developing an evaluated curriculum of perinatal OUD provider education.
- Trial name
- NCT04448015
- Testing
- Perinatal Opioid Use Disorder Education and Enhanced Perinatal Care
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of Utah
Autism
Program to Improve Dental Care: Children With ASD
Children, aged 5-12, with autism spectrum disorder (ASD) who have difficulty with dental visits and daily oral hygiene will complete 3 dental assessments at baseline, 3 months, and 6 months.
- Trial name
- NCT03546504
- Testing
- Procedure alteration and occupational therapy
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Utah
Prostate Cancer
Radium Ra 223 With Enzalutamide Compared to Enzalutamide Alone in Men With Metastatic Castration Refractory Prostate Cancer
Study of Radium Ra 223 dichloride with enzalutamide compared to enzalutamide alone in men with metastatic castration refractory prostate cancer
- Trial name
- NCT02199197
- Testing
- Radium Ra 223 Dichloride, Enzalutamide
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- University of Utah
Metastatic Adenocarcinoma
Evaluating Safety & Efficacy Belinostat Combo w Nivo Alone & w Ipi in Patients w Treated Metastatic/Advanced Carcinomas w ARID1A Lof Mutation
This is an open-label Phase I trial designed to determine the phase 2 recommended dose (RP2D) of belinostat in combination with nivolumab with or without ipilimumab.
- Trial name
- BENEFIT (NCT04315155)
- Testing
- Belinostat, nivolumab, ipilimumab
- Sponsor
- University of Utah
Diabetes Mellitus, Type 2
Combining Flash Glucose Monitoring and Online Peer Support to Improve Outcomes in Hispanics With Type 2 Diabetes
Currently, Hispanic Spanish-speaking individuals are not receiving culturally appropriate diabetes care. Lack of knowledge impacts several areas of type 2 diabetes (T2D) management, including healthy eating and being physically…
- Trial name
- NCT03799796
- Testing
- Flash Glucose Monitoring with Online Peer Support
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Utah
Venous Thromboembolism, Deep Venous Thrombosis
Minimization of Bleeding Related Adverse Drug Events in Plastic & Reconstructive Surgery
Plastic and reconstructive surgeons consistently create large, raw surfaces as part of their operative procedures. Thus, plastic \& reconstructive surgery patients are among those at highest risk for anticoagulant-associated…
- Conditions
- Venous Thromboembolism, Deep Venous Thrombosis, Pulmonary Embolus, Reconstructive Surgery
- Trial name
- NCT03212365
- Testing
- Fixed dose, Variable dose
- Where
- 2 sites in United States
- Volunteers
- 295 people
- Sponsor
- University of Utah
MRI Scans
Comparison of Quantitative MRI Perfusion Methods With Quantitative PET Perfusion Imaging
This work seeks to develop, evaluate and use new MRI methods for non-invasive quantitative assessment of myocardial perfusion and perfusion reserve (MPR), and to compare with quantitative PET imaging.
- Trial name
- NCT02608944
- Testing
- Adenosine, Regadenoson, O-15 labeled radioactive water
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Utah
Pain, Acute, Pain, Joint
Preoperative Psychosocial Support for Postoperative Recovery and Health: Mechanistic Substudy
This was a single site, three-arm, parallel group randomized clinical trial that compared the effect of three preoperative psychosocial interventions on knee and hip replacement patients' preoperative pain intensity and…
- Conditions
- Pain, Acute, Pain, Joint, Pain
- Trial name
- NCT04520958
- Testing
- Mindfulness of Breath, Mindfulness of Pain, Cognitive-Behaviorally Based Pain Psychoeducation
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- University of Utah
Autistic Disorder
Building Social Skills With Interdisciplinary Process Drama in ASD
This is a one group pre-post feasibility study of an interdisciplinary (theatre, Occupational Therapy (OT) and Speech Language Pathology (SLP)) intervention targeted at social skill development in children, aged 3-4.
- Trial name
- NCT03536351
- Testing
- Interdisciplinary process drama
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Utah
Anesthesia
Audiovisual Distraction for Patients Undergoing Total Knee or Hip Replacement Surgery
The primary purpose of this study is to investigate whether audiovisual distraction can lead to a reduction in standard of care administered intraoperative propofol consumption compared to those who receive propofol sedation…
- Trial name
- NCT03191838
- Testing
- Audiovisual Distraction
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Utah
High Risk Hematologic Malignancies
Phase I/II Study of Treg/Tcon Addback to Partially Matched Related Donor Stem Cells With Myeloablative Conditioning and Post-transplant Cyclophosphamide for High Risk Hematologic Malignancies
Open label, dose finding trial to assess the efficacy of Treg/Tcon addback to partially matched related donor stem cells. The maximum tolerated dose will be established using 3 subjects per dose level, with an expansion cohort at…
- Trial name
- NCT01818479
- Testing
- stem cell transplant
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Utah