Clinical trials: sponsored by University of Utah
Prematurity, Nephrocalcinosis
Preterm Infants and Nephrocalcinosis
Nephrocalcinosis (NC), defined as calcification of renal tissue, has been reported to occur in 7-41% of premature infants. Causes of NC are likely multi-factorial, and infants born prematurely and with very low birth weight…
- Conditions
- Prematurity, Nephrocalcinosis, Hypercalciuria
- Trial name
- NC (NCT02438267)
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of Utah
Cancer
Cancer Symptom Monitoring Telephone System With Nurse Practitioner (NP) Follow up
The purpose of this prospective trial is to test a daily telephone based automated symptom monitoring and response system to track and further treat unrelieved symptoms for patients living at home during chemotherapy treatment as…
- Trial name
- NCT01973946
- Testing
- Symptom Alert and Coaching
- Where
- 2 sites in United States
- Volunteers
- 358 people
- Sponsor
- University of Utah
Cancer
Cancer & Chemotherapy Symptom Management Using an Automated Telephone Reporting System
The purpose of this study was to test the efficacy of a computer-based automated symptom monitoring telephone system used by patients who received chemotherapy for their cancer to communicate unrelieved symptoms they experienced…
- Trial name
- NCT01979146
- Testing
- Provider Unrelieved Symptom Alert
- Where
- 3 sites in United States
- Volunteers
- 250 people
- Sponsor
- University of Utah
Stage III or IV Melanoma
Ipilimumab and Dabrafenib in the 1st Line Tx of Unresectable Stage III/IV Melanoma
Phase I/II study of ipilimumab concurrent ipilimumab and dabrafenib as first line treatment in Stage III or IV melanoma. Assessing safety of Ipilimumab and dabrafenib in combination. Also, assessing disease control rates.
- Trial name
- NCT02200562
- Testing
- ipilimumab and dabrafenib
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Utah
Gastrointestinal Stromal Tumors, Cancer Brain
Study of Imatinib and Peginterferon α-2b in Gastrointestinal Stromal Tumor (GIST) Patients
Imatinib (IM) has dramatically improved survival of gastrointestinal stromal tumors (GIST). However, most patients become resistant to IM in less than two years.
- Conditions
- Gastrointestinal Stromal Tumors, Cancer Brain, Solid Tumors
- Trial name
- NCT00585221
- Testing
- Peginterferon-alpha 2b (PegIFNa2b);, Imatinib
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Utah
Pregnancy
The Copper T380A IUD vs. Oral Levonorgestrel for Emergency Contraception
The purpose of this study is to see if women presenting for emergency contraception (EC) and choose the copper intrauterine device (IUD) will have fewer unplanned pregnancies in the next year compared to women who choose oral…
- Trial name
- IUD EC (NCT00966771)
- Testing
- Copper T380 IUD, Oral levonorgestrel
- Where
- 2 sites in United States
- Volunteers
- 548 people, healthy volunteers welcome
- Sponsor
- University of Utah
Prediabetes
Mitochondrial-related Platelet Transcript Expression Levels in Pre-diabetic Subjects Randomized to Metformin or Placebo
Diabetes mellitus (DM) imposes an approximate 2-fold increased risk of atherothrombosis. Patients with type 2 DM have a 2- to 4-fold increase in the risk of coronary artery disease (CAD) and atherothrombotic complications.
- Trial name
- MAP-2 (NCT02682121)
- Testing
- Metformin
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of Utah
Erythropoietic Protoporphyria (EPP), X Linked Erythropoietic Protoporphyria
Effect of Isoniazid on Protoporphyrin Levels in Erythropoietic Protoporphyria
In erythropoietic protoporphyria there is an accumulation of protoporphyrin IX (PPIX) in the plasma and liver. The reason it builds up is either the last step to make heme, insertion of iron into PPIX, is rate limiting or there…
- Trial name
- INHEPP (NCT01550705)
- Testing
- Isoniazid
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Utah
Stroke
Sildenafil and Stroke Recovery
This is a small, pilot randomized clinical trial of administering sildenafil citrate to individuals within 10 days of ischemic stroke who have motor impairment and who are undergoing inpatient rehabilitation compared to placebo.
- Trial name
- NCT02628847
- Testing
- sildenafil citrate
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Utah
Cerebral Palsy, Sensorimotor Deficits
A Study of Neurophysiologically Based Occupational Therapy Intervention (NBOTI) for Feeding in the NCCU.
Many critically ill newborns in the neonatal intensive care (NICU) or critical care unit (NCCU) environment develop feeding and movement problems.
- Conditions
- Cerebral Palsy, Sensorimotor Deficits, Sensory Processing Disorder, Feeding Problems
- Trial name
- NBOTI (NCT00766051)
- Testing
- The intervention group: Neurophysiologically Based Occupational Therapy Intervention (NBOTI)
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- University of Utah
Economic Problems
Evaluating Patient and Physician Cost Knowledge in the Emergency Department
The purpose of this study is to identify existing cost knowledge of Emergency Medicine (EM) physicians and patients and investigates its reported impacts on medical compliance.
- Trial name
- NCT01883778
- Where
- United States
- Volunteers
- 512 people, healthy volunteers welcome
- Sponsor
- University of Utah
Pain, Ankle Sprain
Efficacy of PENNSAID® for Pain Management in the Emergency Department
The primary objective of this study is to compare the pain relieving effect and speed of onset of PENNSAID to that of standard oral diclofenac under double blind conditions using a growth curve approach to pain measurement.
- Trial name
- NCT01350622
- Testing
- PENNSAID, Diclofenac hydroxyethylpyrrolidine
- Where
- United States
- Sponsor
- University of Utah
Drug Interactions, Pharmacokinetics
Influence of Rifampin Co-Administration on the Pharmacokinetic Profile of Daptomycin
The purpose of this study is to understand how an antibiotic, rifampin, may change the blood levels of another antibiotic, daptomycin, in the body.
- Trial name
- NCT02097953
- Testing
- Daptomycin, Rifampin
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Utah
Anesthesia, Local
Serum Bupivacaine Concentration Levels After Injection of Liposomal Bupivacaine Into the Knee
Serum levels of bupivacaine over time after peri-articular injection of a mixture of liposomal bupivacaine and plain bupivacaine during total knee arthroplasty.
- Trial name
- NCT02626559
- Testing
- liposomal bupivacaine/plain bupivacaine peri-articular injection
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Utah
Spinal Muscular Atrophy
Valproic Acid in Ambulant Adults With Spinal Muscular Atrophy
The primary objective of this proposal is to determine whether oral VPA is effective in treating SMA in adult patients.
- Trial name
- VALIANTSMA (NCT00481013)
- Testing
- Valproic Acid (VPA)
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Utah
Substance-Related Disorders
Behavioral Treatment for Substance Abuse
This pilot project will evaluate a new mind-body intervention called Mind-Body Bridging (MBB) for reducing substance abuse problems in women who are undergoing a substance abuse treatment program.
- Trial name
- NCT01438346
- Testing
- Substance Abuse Education, Mind-body Bridging
- Where
- 2 sites in United States
- Volunteers
- 38 people
- Sponsor
- University of Utah
Sleep Disturbance, Persian Gulf War Syndrome in Veteran
Clinical Benefits of a Novel Sleep-focused Mind-body Program on Gulf War Illness (GWI) Symptoms
The purpose of this study is to investigate clinical benefits of a novel sleep-focused mind-body program on Gulf War Illness (GWI) symptoms.
- Trial name
- NCT01543997
- Testing
- Mind-Body Bridging Program, Supportive Education
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- University of Utah
Chronic Kidney Disease
Effects of a Walking Intervention in Older Patients With Chronic Kidney Disease: Feasibility Study
Chronic kidney disease (CKD) affects more than 26 million individuals (13 percent) of the U.S. population, with a projected 70 percent increase by the year 2015 to over 40 million individuals.
- Trial name
- NCT02155127
- Testing
- walking
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Utah
Diabetes
Physical Activity and Functioning in Home Dialysis Patients
This study will compare physical activity levels and physical functioning in patients treated with home dialysis vs. those treated with in-center dialysis.
- Trial name
- NCT01602718
- Testing
- exercise training
- Volunteers
- 120 people
- Sponsor
- University of Utah
Healthy
Nutrient Regulation of Amino Acid Transporters in Aging Human Skeletal Muscle
The goal of the research project is to determine how aging and inactivity reduce the muscle anabolic effect of nutrients and lead to muscle and functional loss.
- Trial name
- NCT01669590
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Utah