Clinical trials: sponsored by University of Utah
Decision Making
Evaluation of Drug Display in Critical Care Setting
To assess the clinical utility of the graphical medication monitor, results of the anesthetics for which the display was present will be compared to the results of the anesthetics in which there was no display.
- Trial name
- NCT00715507
- Testing
- medication monitor
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Utah
Cardiac Arrest, Hyperventilation
Investigation of a Novel Turbine-driven Ventilator for Use in Cardiopulmonary Resuscitation
The objective of this study is to determine whether healthcare professionals trained in CPR can deliver more effective ventilations during CPR using the Handivent, a novel turbine-driven ventilator as compared to bag-valve-mask…
- Trial name
- NCT02743299
- Testing
- Handivent Ventilator
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Utah
Respiratory Complications Due to Anesthesia
A Comparison of Controlled Ventilation With the V60 Non-Invasive Ventilator vs. Traditional Mask Ventilation
The purpose of this study is to determine whether an experienced anesthesia provider can adequately and/or easily mask ventilate an anesthetized patient with a commercial non-invasive ventilator device.
- Trial name
- NCT02623270
- Testing
- Noninvasive Ventilator, V60 (Philips), Manual Bag
- Volunteers
- 20 people
- Sponsor
- University of Utah
Emergency Contraception
Study of the Copper IUD or Oral Levonorgestrel and the Levonorgestrel IUD for Women Seeking Emergency Contraception
The purpose of this study is to see how often women who come to a family planning clinic for emergency contraception, the morning after pill, are willing to use either the copper IUD or the levonorgestrel IUD.
- Trial name
- COLIEC (NCT01963962)
- Testing
- Copper IUD, Levonorgestrel IUD
- Where
- United States
- Volunteers
- 188 people
- Sponsor
- University of Utah
Corneal Neovascularization, Corneal Graft Failure
Subconjunctival IVIg (Gamunex-C) Injection for Corneal Neovascularization and Inflammatory Conditions
The purpose of the study is to test the investigational drug Gamunex-C on the growth of blood vessels over the cornea. This study is being conducted by Dr. Balamurali Ambati at the Moran Eye Center at the University of Utah.
- Conditions
- Corneal Neovascularization, Corneal Graft Failure, Anterior Segment Inflammation
- Trial name
- NCT02042027
- Testing
- Gamunex-C
- Where
- United States
- Sponsor
- University of Utah
Gastroesophageal Reflux, Asthma
Elucidation of Acid-Induced Pulmonary Inflammation
This study will evaluate how heartburn may lead to different types of inflammation in one's airways. Additionally, the study will determine whether aggressive treatment of heartburn results in improvement in both symptoms of…
- Trial name
- NCT00361972
- Testing
- lansoprazole
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Utah
Cancer
Molecular Signature of Valproic Acid in Breast Cancer With Functional Imaging Assessment - a Pilot
The investigators' hypothesis is that valproic acid given before surgery for newly diagnosed breast cancer will increase breast tumor histone acetylation at tolerable doses and that the increase in breast tumor histone…
- Trial name
- VAST (NCT01007695)
- Testing
- Valproic Acid
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Utah
Clinical Interpretation of Capnography Waveforms
Online Survey of Clinicians to Learn About Their Interpretation of Capnography Waveforms
This online survey presents capnography waveforms and asks the survey participants to give feedback about their interpretation of the patient status, both in the form of a score and a set of text to describe their interpretation.
- Trial name
- NCT02822183
- Testing
- Online Survey
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Utah
Lower Extremity Periarticular Fractures
Early Standardized Weight Bearing Utilizing Immersion Therapy Following Periarticular Lower Extremity Fractures
The purpose of this prospective study is evaluate the effect of a standardized early weight bearing physical therapy protocol that utilizes immersion therapy on the clinical outcomes of lower extremity periarticular fractures.
- Trial name
- NCT01457326
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- University of Utah
Cancer, Myeloma
Effect of Low Dose Bortezomib on Bone Formation in Smoldering Myeloma Patients
OBJECTIVES Primary: To evaluate the bone anabolic effect of bortezomib in patients with smoldering myeloma. Secondary: To evaluate the effect of bortezomib on the natural history of smoldering myeloma.
- Conditions
- Cancer, Myeloma, Multiple Myeloma
- Trial name
- NCT00983346
- Testing
- Bortezomib
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Utah
Pulmonary Ventilation
Observing Changes in Ventilation Pattern During Procedural Sedation
The ventilation (respiratory rate, tidal volume and end-tidal CO2) was monitored for patients receiving procedural sedation during endoscopy procedures in order to observe what changes commonly occur.
- Trial name
- NCT02825433
- Testing
- No intervention, only ventilation monitoring
- Volunteers
- 160 people
- Sponsor
- University of Utah
Healthy
In-Vivo Assessment of Silver Biomaterial Nano-Toxicity 32 Ppm
The investigators propose to study oral commercial silver nanoparticle products on human enzyme activity.
- Trial name
- NCT01405794
- Testing
- 32ppm Silver Particle
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Utah
Patent Ductus Arteriosus, Prematurity
Early Versus Late Use of Ibuprofen for Patent Ductus Arteriosus (PDA) Closure
The primary objective is to evaluate the Patent Ductus Arteriosus (PDA) closure rate of early vs. late use of Ibuprofen (Ibu). The investigators believe that early use of Ibu will have a higher PDA closure rate than later use of…
- Trial name
- NCT00833365
- Testing
- Ibuprofen
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Utah
Mood
Differential Effects of Clomiphene Citrate in Women Undergoing Superovulation
Clomiphene citrate is commonly used for ovulation induction in women with anovulation, correction of luteal phase deficiency or for superovulation as empiric therapy for unexplained infertility.
- Trial name
- NCT01291056
- Testing
- Clomiphene
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Utah
Pilon Fracture, Arthritis
Anterior Tibiotalar Arthrodesis With Blade Plate Fixation
The aim of this study is to evaluate the clinical and radiographic outcomes of patients who have previously undergone tibiotalar arthrodesis using an anterior approach with blade-plate fixation for tibiotalar arthritis secondary…
- Trial name
- NCT01818466
- Sponsor
- University of Utah
Electronic Health Records
VA Integrated Medication Manager
The purpose of this study is to advance the science of healthcare informatics and to improve medication management through the development of a new approach to the electronic medical record called the Integrated Medication…
- Trial name
- IMM (NCT01787175)
- Testing
- Integrated Medication Manager
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Utah
Adenomatous Polyposis Coli
A Clinical Trial of COX and EGFR Inhibition in Familial Polyposis Patients
The purpose of this study is to determine in a randomized, placebo-controlled, phase II trial if the combination of sulindac and erlotinib causes a significant regression of duodenal and colorectal adenomas in familial…
- Trial name
- FAPEST (NCT01187901)
- Testing
- Erlotinib, Sulindac
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- University of Utah
Chronic Myelomonocytic Leukemia
A Study of 5-Azacitidine (Vidaza®) in Patients With Chronic Myelomonocytic Leukemia
The primary objective of this study is: Response to treatment will be evaluated according to the revised International Working Group (IWG) categories natural history, hematologic improvement and cytogenetic response1;2.
- Trial name
- NCT01350947
- Testing
- 5-Azacitidine
- Where
- 3 sites in United States
- Volunteers
- 11 people
- Sponsor
- University of Utah
Pancreatic Ductal Adenocarcinoma
A Biomarker Study to Identify Predictive Signatures of Response to LDE225 (Hedgehog Inhibitor) In Patients With Resectable Pancreatic Cancer
Pancreatic cancer is considered a rare form of cancer with about 277,000 new cases diagnosed in 2008 world-wide, which is about 2.5% of all forms of cancer.
- Trial name
- NCT01911416
- Testing
- LDE225
- Where
- United States
- Sponsor
- University of Utah
Chronic Obstructive Pulmonary Disease
Exercise in Health and Chronic Obstructive Pulmonary Disease
The purpose of this study is to find out more about the effects of chronic obstructive pulmonary disease (COPD) on the function of blood vessels, the heart, and muscle at rest and during exercise.
- Trial name
- NCT02300064
- Testing
- Knee-extensor exercise test, Exercise test with restricting/releasing blood flow, Exercise test with variable oxygen concentration and MRI
- Where
- United States
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- University of Utah