Clinical trials: sponsored by University of Virginia
Major Depressive Disorder
Study of Supplementation of Antidepressants With Fish Oil to Improve Time to Clinical Response
This study will be a randomized controlled trial set in an outpatient clinic, involving patients with major depressive disorder, who will be treated with antidepressant therapy, which will be individually agreed upon by the…
- Trial name
- SADFAT (NCT00963196)
- Testing
- Omega-3 fatty acid, Bovine gelatin capsules
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- University of Virginia
Attention Deficit Hyperactivity Disorder
Classroom-Level Intervention to Promote Peers' Acceptance of Children With Attention Deficit Hyperactivity Disorder (ADHD)
Children with Attention-Deficit/Hyperactivity Disorder (ADHD) comprise about 5-10% of the elementary school-age population. One place where children with ADHD have great difficulty is in being accepted by peers and in making…
- Trial name
- NCT01133028
- Testing
- Behavioral contingency management, Tolerance training
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Polycystic Ovary Syndrome
Acupuncture for Polycystic Ovarian Syndrome
This is a randomized control trial of acupuncture for women with polycystic ovary syndrome. The study is triple-blinded.
- Trial name
- NCT00602940
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Respiratory Distress Syndrome, Newborn
Randomized Controlled Trial of Surfactant Administration by Laryngeal Mask Airway (LMA)
In this protocol we will conduct a randomized controlled trial where babies with respiratory distress syndrome (RDS) who have not yet reached criteria for intubation, will be randomized to receive surfactant by LMA or to continue…
- Trial name
- NCT00599651
- Testing
- Surfactant administered via Laryngeal Mask Airway (LMA), standard of care (nasal CPAP and supplemental oxygen)
- Where
- United States
- Volunteers
- 380 people
- Sponsor
- University of Virginia
HIV Infections, Cocaine Dependence
Pharmacotherapy for HIV+ Stimulant Dependent Individuals
The hypotheses of this study are: 1. Ondansetron will show a decrease in cocaine use from baseline in individuals with HIV who are cocaine using. 2.
- Trial name
- NCT00599573
- Testing
- ondansetron
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Virginia
Metastatic Cancer
Surgery and Intrapleural Docetaxel in Treating Patients With Malignant Pleural Effusion
RATIONALE: Giving drugs, such as docetaxel, directly into the pleura after surgery to drain the pleural effusion may help keep fluid from building up again.
- Trial name
- NCT00114205
- Testing
- docetaxel, therapeutic thoracoscopy
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Virginia
Cancer, Insomnia
Improving the Sleep of Cancer Patients Using an Internet-Based Program
The purpose of this study is to determine whether an Internet-based program, Sleep Healthy Using the Internet (SHUTi, or "Shut-Eye"), can help to improve the sleep of people who are in remission from cancer and experiencing…
- Trial name
- SHUTi-C (NCT00716872)
- Testing
- Sleep Healthy Using the Internet (SHUTi), Hypnosis recordings
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Virginia
Lung Cancer
Docetaxel and Thalidomide as Second-Line Therapy in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer
RATIONALE: Drugs used in chemotherapy, such as docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00114192
- Testing
- docetaxel, thalidomide
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- University of Virginia
Stress
Study Examining Stress During Pregnancy
Researchers at UVa Health System are interested in how women experience and deal with stress during pregnancy. Participants will be randomly assigned either to engage in coping strategies on one's own or to receive 6 weeks of…
- Trial name
- NCT00307320
- Testing
- Relaxation Training
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Virginia
Head and Neck Cancer
Carboplatin, Capecitabine, and Radiation Therapy in Treating Patients With Stage III or Stage IV Head and Neck Cancer
RATIONALE: Drugs used in chemotherapy, such as carboplatin and capecitabine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00114153
- Testing
- capecitabine, carboplatin, conventional surgery
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Virginia
Low Back Pain
Ultrasound Assessment During Exercise
This study evaluates the ability of the transverse abdominis (TrA) to contract during and after two different types of exercise - either sling based exercise or traditional core stability exercise.
- Trial name
- Redcord RUSI (NCT01015846)
- Testing
- Exercise, Core stability exercise
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Virginia
Melanoma
A Pilot Study of Intraoperative Gamma Camera Imaging During Sentinel Node Biopsy for Melanoma
This is a single-institution pilot study seeking preliminary evidence of the usefulness of mobile gamma cameras in patients undergoing sentinel node biopsy for melanoma.
- Trial name
- MEL50 (NCT00912730)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Virginia
Tibial Femoral Knee Osteoarthritis, Osteoarthritis
The Effect of Transcutaneous Electrical Nerve Stimulation on Quadriceps Central Activation and Gait
Participants diagnosed with tibial femoral knee osteoarthritis will be assigned to one of three treatment groups including: active transcutaneous electrical nerve stimulation (TENS), placebo TENS, and a control group.
- Trial name
- NCT00976079
- Testing
- Transcutaneous electrical nerve stimulation (TENS)
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- University of Virginia
Gait, Flexibility
Age-Related Gait Changes and Hip Flexibility
Based on their preliminary quantitative gait findings suggesting that limited passive hip extension range is a key functionally limiting impairment affecting gait, the investigators propose a supervised, specific stretching…
- Trial name
- NCT00924261
- Testing
- Hip Stretch, Shoulder Stretch
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Attention Deficit Hyperactivity Disorder
Enhancing ADHD Driving Performance With Stimulant Medication
Among children, attention-deficit/hyperactivity disorder (ADHD) is associated with an increased risk for accidents, especially bicycle and pedestrian (Leibson 2001; Jensen 1988; DiScala 1998).
- Trial name
- NCT00572026
- Testing
- Methylphenidate Transdermal System
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Virginia
Stroke, Hyperglycemia
Glucose Regulation in Acute Stroke Patients (GRASP) Study
The purpose of this study is to assess the feasibility, safety and preliminary efficacy of the use of insulin infusions as treatment for hyperglycemic acute ischemic stroke patients.
- Trial name
- NCT00282867
- Testing
- IV glucose insulin and potassium, GIK, standard care
- Where
- 2 sites in United States
- Volunteers
- 74 people
- Sponsor
- University of Virginia
Cognitive/Functional Effects, Depression
Modafinil in Treating Fatigue in Patients With Cancer
RATIONALE: Modafinil may help relieve fatigue and improve quality of life in patients with cancer. PURPOSE: This clinical trial is studying how well modafinil works in treating fatigue in patients with cancer.
- Conditions
- Cognitive/Functional Effects, Depression, Fatigue, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00112515
- Testing
- modafinil, cognitive assessment, psychosocial assessment and care
- Where
- United States
- Sponsor
- University of Virginia
Melanoma
Evaluation of the Effects of Local Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) in Adjuvant Administration on Dendritic Cells in Skin of Melanoma Patients and in Sentinel Lymph Nodes: MEL38
Goal: To characterize the cellular events that occur in vivo after vaccination with an emulsion of GMCSF-in-adjuvant. Design: Open-label, single dose study in two stages.
- Trial name
- MEL38 (NCT00912574)
- Testing
- GM-CSF-in-adjuvant, Montanide ISA-51, GM-CSF and Montanide ISA-51
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Virginia
Metabolic Syndrome X
Comparison of Two Different Diets on Health Outcomes
The purpose of this study is to compare the effects of a low-carbohydrate diet and a high-carbohydrate, high-fiber diet, on insulin sensitivity and blood chemicals considered risk markers for heart disease, in persons with the…
- Trial name
- NCT00269646
- Testing
- Low-carbohydrate and high-carbohydrate diets
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Diabetes Mellitus, Type 1
UVA Islet Cell Transplantation in Patients With Type I Diabetes
This protocol will provide islet cell transplantation to two separate populations in need of a pancreas transplant: Group I: Islet Cell Transplantation in Type I Diabetics without Kidney Problems Group II: Islet Cell…
- Trial name
- NCT00605592
- Testing
- Pancreatic Islets of Langerhans Cell Transplant
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Virginia