Clinical trials: sponsored by University of Washington
Adenocarcinoma of the Prostate, Castration-resistant Prostate Cancer
Cabozantinib in Men With Castration-Resistant Prostate Cancer
This pilot clinical trial studies cabozantinib in treating men with castration-resistant prostate cancer. Cabozantinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
- Conditions
- Adenocarcinoma of the Prostate, Castration-resistant Prostate Cancer, Recurrent Prostate Cancer, Stage III Prostate Cancer
- Trial name
- NCT01703065
- Testing
- Cabozantinib
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Washington
Metastatic Malignant Neoplasm in the Lung, Recurrent Disease
Proton Beam Re-Irradiation in Thoracic Cancers
This pilot clinical trial studies proton beam radiation therapy in treating patients with thoracic cancer that has come back and have received prior radiation therapy.
- Conditions
- Metastatic Malignant Neoplasm in the Lung, Recurrent Disease, Thoracic Neoplasm
- Trial name
- NCT02204761
- Testing
- Proton Beam Radiation Therapy
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- University of Washington
Substance Use Disorder
Mindful Awareness in Body-Oriented Therapy for Women's Substance Abuse Treatment
The primary purpose of this exploratory and developmental study is to evaluate a mind-body intervention for relapse prevention for women in addiction treatment.
- Trial name
- NCT01280916
- Testing
- Mindful Awareness in Body-oriented Therapy
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Washington
B Acute Lymphoblastic Leukemia, B Lymphoblastic Lymphoma
Etoposide, Prednisone, Vincristine Sulfate, Cyclophosphamide, and Doxorubicin Hydrochloride With Asparaginase in Treating Patients With Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma
This phase II trial studies how well etoposide, prednisone, vincristine sulfate, cyclophosphamide, and doxorubicin hydrochloride with asparaginase work in treating patients with acute lymphoblastic leukemia or lymphoblastic…
- Conditions
- B Acute Lymphoblastic Leukemia, B Lymphoblastic Lymphoma, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent B Lymphoblastic Lymphoma
- Trial name
- NCT02538926
- Testing
- Asparaginase, Cyclophosphamide, Doxorubicin Hydrochloride
- Where
- United States
- Sponsor
- University of Washington
Critical Illness, Malnutrition
Increasing Enteral Protein Intake in Critically Ill Trauma and Surgical Patients
Published guidelines recommend at least 2 gm/kg/day of protein for critically ill surgical patients. It may not be possible to achieve this level of intake using polymeric enteral nutritional formula and protein or amino acid…
- Conditions
- Critical Illness, Malnutrition, Enteral Nutrition, Protein Supplementation
- Trial name
- NCT03733782
- Testing
- Modular enteral protein - Prosource
- Volunteers
- 118 people
- Sponsor
- University of Washington
Blood Pressure, Inflammation
Mental Stress & Diesel Exhaust on Cardiovascular Health
This study uses an experimental design to conduct a double-blind, randomized, crossover study where participants receive both diesel exhaust and a mental stress test in a controlled setting.
- Conditions
- Blood Pressure, Inflammation, Catecholamines
- Trial name
- DESTRESS (NCT03467997)
- Testing
- Trier social stress test, Diesel exhaust
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Washington
Tooth Movement, Malocclusion
Accelerated Tooth Movement With AcceleDent® and Aligners - a Pilot Project
The AcceleDent® device has been introduced to the specialty of orthodontics in order to reduce treatment time. The theory behind AcceleDent® is that high frequency vibratory forces (30Hz) delivered to the teeth will stimulate the…
- Trial name
- NCT02438280
- Testing
- AcceleDent, Vibrational Device
- Where
- 3 sites in United States, Canada
- Volunteers
- 27 people
- Sponsor
- University of Washington
Hand Injuries, Hand Injuries and Disorders
Early Ultrasound-guided Nerve Block for Painful Hand Injuries in the Emergency Department
This study aims to determine whether early initiation of temporary nerve block therapy improves patient satisfaction, decreases patient pain and discomfort, decreases the use of dangerous medications such as narcotics, and frees…
- Trial name
- NCT03195413
- Testing
- Ultrasound-guided forearm nerve block, 1:1 volume measured solution of: 1% lidocaine without epinephrine and 0.5% bupivacaine without epinephrine, Bedside ultrasound machine
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Washington
Chronic Post Traumatic Headache
Treatment of Chronic Post-Traumatic Headache With OnabotulinumtoxinA
This study will provide evidence on whether the use of an FDA-approved drug therapy for the treatment of chronic migraine (OnabotulinumtoxinA) shows similar efficacy for treatment of chronic headaches caused by traumatic injury…
- Trial name
- NCT02160535
- Testing
- OnabotulinumtoxinA
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Washington
Wounds and Injuries, Trauma
Study of Team Leadership Training Effect on Patient Care
Brief Summary: Trauma is a major public health burden; it is the fifth most common cause of mortality overall in the US and accounts for the majority of deaths in patients younger than 45.
- Trial name
- NCT03155490
- Testing
- Leadership training
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University of Washington
HIV and Tuberculosis Co-infection
Nutritional Support for HIV-Tuberculosis Co-infected Adults in Senegal, West Africa
Food insecurity can contribute to poor adherence to both tuberculosis treatment and antiretroviral therapy (ART). Interventions that target food insecurity have the potential to improve treatment adherence and decrease mortality.
- Trial name
- NCT03711721
- Testing
- Food basket, Ready-to-Use Therapeutic Food
- Volunteers
- 26 people
- Sponsor
- University of Washington
Cutaneous T-cell Lymphoma Stage I, Cutaneous T-cell Lymphoma Stage II
Vorinostat in Patients With Primary Cutaneous T-Cell Lymphoma
This phase II trial studies the side effects and how well vorinostat works in treating patients with primary cutaneous T-cell lymphoma.
- Conditions
- Cutaneous T-cell Lymphoma Stage I, Cutaneous T-cell Lymphoma Stage II, Cutaneous T-cell Lymphoma Stage III, Cutaneous T-cell Lymphoma Stage IV
- Trial name
- NCT00958074
- Testing
- vorinostat, flow cytometry, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Washington
Sinusitis, Chronic, Cystic Fibrosis With Other Manifestations
SynRinse Irrigation Pilot (SIP) Trial
Assess if the use of SYNRINSE can improve short-term subjective and objective outcome measures after one week in patients with active Chronic Rhinosinusitis (CRS) who have had prior sinus surgery.
- Trial name
- NCT03154541
- Testing
- Synrinse
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Washington
Multiple Sclerosis, Spinal Cord Injury
Power Over Pain (POP) Study
Many individuals with multiple sclerosis (MS), spinal cord injury (SCI), acquired amputation (AMP), muscular dystrophy (MD), and low back pain (LBP) experience pain. There has been little research on how to treat this pain.
- Conditions
- Multiple Sclerosis, Spinal Cord Injury, Chronic Pain, Other and Unspecified Amputation Stump Complications
- Trial name
- POP (NCT01800604)
- Testing
- Pain Self-Management Intervention #1, Pain Self-Management Intervention #2, Pain Self-Management Intervention #3
- Where
- United States
- Volunteers
- 177 people
- Sponsor
- University of Washington
Low Back Pain, Headache
Pain Quality Study
One way to better understand how various treatments for pain differ is to determine the effects of these treatments on different pain qualities or characteristics.
- Conditions
- Low Back Pain, Headache, Fibromyalgia
- Trial name
- NCT01321190
- Where
- United States
- Volunteers
- 307 people
- Sponsor
- University of Washington
HIV Infection, Herpes Simplex, Genital
Herpes Simplex Virus Type 2 (HSV-2) Suppression to Prevent HIV Transmission
The University of Washington has received funding to conduct a proof-of-concept trial to assess the impact of suppression of genital herpes on HIV infectiousness.
- Conditions
- HIV Infection, Herpes Simplex, Genital, Sexually Transmitted Diseases
- Trial name
- NCT00194519
- Testing
- Generic acyclovir
- Where
- 13 sites in Botswana, Kenya and 5 more
- Volunteers
- 3,408 people
- Sponsor
- University of Washington
Substance Use Disorder
Body-oriented Therapy for Women in SUD Treatment
The long-term objective of this study is to improve women's substance use disorder (SUD) treatment. The immediate project goal is to test the efficacy of an innovative mind-body intervention, Mindful Awareness in Body-Oriented…
- Trial name
- NCT01960036
- Testing
- Mindful Awareness in Body-oriented Therapy, Womens Health Education
- Where
- United States
- Volunteers
- 217 people
- Sponsor
- University of Washington
Chronic Kidney Diseases, Type 2 Diabetes
Continuous Glucose Monitoring to Assess Glycemia in Chronic Kidney Disease - Changing Glucose Management
The goal of this study is to test whether a dipeptidyl peptidase-4 inhibitor, compared with a sulfonylurea, improves time in normal blood glucose range and reduces blood glucose variability.
- Trial name
- CANDY-CANE (NCT02608177)
- Testing
- Linagliptin, Glipizide
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Washington
Recurrent Salivary Gland Cancer, Stage IVA Salivary Gland Cancer
Eribulin Mesylate in Treating Patients With Recurrent or Metastatic Salivary Gland Cancer
Researchers are doing a research study to examine the use of eribulin (eribulin mesylate) in patients with salivary gland cancer. Researchers want to know if eribulin is safe and effective in treating salivary gland cancer.
- Conditions
- Recurrent Salivary Gland Cancer, Stage IVA Salivary Gland Cancer, Stage IVB Salivary Gland Cancer, Stage IVC Salivary Gland Cancer
- Trial name
- NCT01613768
- Testing
- eribulin mesylate
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Washington
Major Depressive Disorder
Games to Overcome Late Life Depression
This is a pilot study divided into two phases. IN phase 1 (completed) participants will be randomized to receive 8 weeks of Problem Solving Therapy (PST) alone or 8 weeks of a cognitive training game called, Evolution (Evo) plus…
- Trial name
- GOLD (NCT02229188)
- Testing
- Problem Solving Therapy, Evolution, Words
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Washington
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