Clinical trials: sponsored by University of Washington
Tuberculosis, HIV I Infection
ThiPhiSA: New Pathways to Prevention From Community TB Screening in South Africa
This study will compare community-delivered, multi-month dispensing of tuberculosis preventive therapy (TPT) to standard-of-care clinic-based TPT delivery in a population of South African adults who are recommended to receive TB…
- Trial name
- ThiPhiSA (NCT06214910)
- Testing
- Community-delivered TB preventive therapy (TPT) - 3 months weekly isoniazid plus rifapentine (3HP), Clinic-link TPT
- Where
- South Africa
- Volunteers
- 301 people
- Sponsor
- University of Washington
Dihydrotestosterone, Periprosthetic Joint Infection (PJI)
Finasteride and Cutibacterium
High levels of Testosterone causes high amounts of skin bacteria (Cutibacterium Acnes) which can go into the skin during a shoulder replacement surgery and cause a terrible infection.
- Conditions
- Dihydrotestosterone, Periprosthetic Joint Infection (PJI), Cutibacterium Acnes
- Trial name
- NCT07731802
- Testing
- Finasteride 1 mg
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Washington
Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8
A Multiple Antigen Vaccine (STEMVAC) for the Treatment of Patients With Stage IV Non-Small Cell Lung Cancer
This phase II trial tests whether CD105/Yb-1/SOX2/CDH3/MDM2-polyepitope plasmid DNA vaccine (STEMVAC) works to shrink tumors in patients with stage IV non-small cell lung cancer.
- Trial name
- NCT05242965
- Testing
- CD105/Yb-1/SOX2/CDH3/MDM2-polyepitope Plasmid DNA Vaccine, Sargramostim, Computed Tomography
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of Washington
Multiple Sclerosis
Single Arm Trial Identifying Barriers and Facilitators to Mindfulness Practice
This observational study will examine what emotional, physical, and environmental factors make it easier or harder for people with multiple sclerosis (MS) and chronic pain to practice mindfulness daily while participating in a…
- Trial name
- NCT07573241
- Testing
- MBCT
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Washington
PrEP Adherence Monitoring
A Hybrid Effectiveness-Implementation Trial of Urine Point-of-Care Assay to Increase PrEP Adherence Among Women in Kenya
The goal of this randomized trial study is to learn if drug-level feedback counseling works to improve oral PrEP adherence in adolescent girls and young women. Researchers will compare urine TFV assay positivity between arms.
- Trial name
- NCT07725679
- Testing
- POC urine TFV test with DLFB
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Washington
Psychological Stress, Social Interaction
Exploring the Decision to Drink (More) Alcohol Following Manipulations of Stress and Social Context
This preregistration documents an experiment examining the effects of acute stress and social context on alcohol-related decision-making. The study uses a 2x2 factorial design (stress vs. control × social vs.
- Trial name
- DoraR00 (NCT07390084)
- Testing
- Stress, Social Context
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Washington
Autism Spectrum Disorder
Iterative Redesign of a Multifaceted Implementation Strategy for a School-based Behavioral Skills Intervention (RUBI)
The increased prevalence of autism spectrum disorder (1 in 36 youth) in the United States along with the exorbitant cost of care of supporting one autistic individual with and without intellectual disability across their lifespan…
- Trial name
- NCT06508515
- Testing
- Unadapted Research Units in Behavioral Intervention (RUBI) implementation strategy, RUBI in Educational Settings (RUBIES)-Team
- Where
- United States
- Volunteers
- 193 people
- Sponsor
- University of Washington
Multiple Sclerosis
Combating Age-related Failure of Myelination in Multiple Sclerosis: An Exploratory Study
This observational, longitudinal study will examine whether physical activity and other potentially modifiable lifestyle factors are associated with changes in myelin, the protective coating around nerve fibers, in older adults…
- Trial name
- MAPMyeMS (NCT07723599)
- Testing
- Observation
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Washington
Anatomic Stage IB Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
STEMVAC in Patients With Early Stage Triple Negative Breast Cancer
This phase II trial studies the effect of DNA plasmid based vaccine (STEMVAC) in treating patients with patients with stage IB-III triple negative breast cancer.
- Conditions
- Anatomic Stage IB Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIA Breast Cancer AJCC v8, Anatomic Stage IIB Breast Cancer AJCC v8
- Trial name
- NCT05455658
- Testing
- CD105/Yb-1/SOX2/CDH3/MDM2-polyepitope Plasmid DNA Vaccine, Sargramostim
- Where
- 3 sites in United States
- Volunteers
- 33 people
- Sponsor
- University of Washington
Hereditary Diseases, Critical Illness
UW ISeqU: Clinical Impact of Whole-genome Sequencing in Adults
The goal of this study is to learn how clinical whole genome sequencing can help identify diagnoses and guide medical care in adults.
- Trial name
- NCT07718971
- Testing
- Genome sequencing
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- University of Washington
Renal Calculi, Ureteral Calculi
Intraoperative Assessment of of Burst Wave Lithotripsy (BWL)
Burst Wave Lithotripsy (BWL) is a novel method of urinary stone fragmentation that uses multi-cycle bursts of low amplitude ultrasound to induce stone fracture.
- Trial name
- NCT03873259
- Testing
- Burst Wave Lithotripsy
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of Washington
Castration-Resistant Prostate Carcinoma, Metastatic Prostate Adenocarcinoma
Supraphysiological Androgen to Enhance Treatment Activity in Metastatic Castration-Resistant Prostate Cancer, SPECTRA Study
This phase II trial studies how well giving testosterone at levels higher than normally found in the body (supraphysiological) works to enhance chemotherapy treatment, and Lutetium 177Lu-prostate specific-membrane antigen…
- Conditions
- Castration-Resistant Prostate Carcinoma, Metastatic Prostate Adenocarcinoma, Stage IVB Prostate Cancer AJCC v8
- Trial name
- NCT06039371
- Testing
- Biopsy Procedure, Biospecimen Collection, Bone Scan
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- University of Washington
Breast Cancer, Stage 0
MRI Characterization of Mammographically Detected DCIS
This is a single institution, prospective observational clinical trial for women with mammographically identified calcifications that may represent ductal carcinoma in situ (DCIS).
- Trial name
- NCT03495011
- Testing
- Breast MRI, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- University of Washington
End Stage Renal Disease on Dialysis
The Home Blood Pressure (BP) Trial
The main study will be a two arm 10-month, cross-over randomized controlled trial of 200 participants treated with end-stage-kidney-disease treated with in-center hemodialysis in the Seattle and San Francisco area comparing a…
- Trial name
- Home-BP (NCT05159999)
- Testing
- Dry weight target adjustment, Anti-hypertensive medications
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Washington
Kidney Stones, Nephrolithiasis
Ultrasound Imaging of Kidney Stones and Lithotripsy
The purpose of this study is to determine whether new software processing of ultrasound images can improve detection and size determination of kidney stones.
- Conditions
- Kidney Stones, Nephrolithiasis, Urolithiasis, Ureter Stones
- Trial name
- NCT02214836
- Testing
- Verasonics Data Acquisition System (VDAS)
- Where
- United States
- Volunteers
- 219 people
- Sponsor
- University of Washington
Gliosis, Obesity
Does What You Eat Affect Your Brain
The purpose of this study is to use magnetic resonance imaging (MRI) to evaluate the human hypothalamus for signs of inflammation in response to specific diets.
- Conditions
- Gliosis, Obesity, Eating
- Trial name
- WYE (NCT05626907)
- Testing
- Diet modification #1, Diet modification #2, Diet modification #3
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Washington
White Spot Lesions, Gingival Inflammation and Bleeding
Topical 10% Povidone-Iodine in Preventing White Spots
The goal of this clinical trial is to learn if topical application on the all surface of 10% Povidone Iodine (Povi-One) in healthy participants in transitional or permanent dentition (10-17 y) prevents new white spot lesions in…
- Trial name
- NCT06616207
- Testing
- Povidone-iodine solution
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Washington
Suicide Prevention
Adapting a Brief Suicide Intervention for Pediatric Primary Care: Enhancing Uptake and Impact
Suicide is a leading cause of death among adolescents in the United States and improving access to high quality just-in-time suicide interventions to reduce risk has important public health implications.
- Trial name
- NCT06499740
- Testing
- Pilot Intervention, Treatment as Usual
- Where
- 3 sites in United States
- Volunteers
- 48 people
- Sponsor
- University of Washington
Colorectal Cancer
Colonoscopy Outreach for Rural Communities Aim 2
This study aims to test the effectiveness of a remotely-delivered patient navigation program for increasing colonoscopy completion for colorectal cancer screening, among rural populations.
- Trial name
- NCT05453630
- Testing
- Patient Navigation, Usual Care Control
- Where
- United States
- Volunteers
- 527 people, healthy volunteers welcome
- Sponsor
- University of Washington
Alcohol Use
CPNF Intervention Development and Testing
The project will develop brief interventions that allow participants to customize which groups they receive feedback for in relation to things such as drinking norms for younger or older students, student athletes, etc.
- Trial name
- Project SHIFT (NCT07036198)
- Testing
- Customizable personalized normative feedback (CPNF), Personalized normative feedback (PNF), Attention-Matched Control (AMC)
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Washington
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.