Clinical trials: sponsored by University of Zurich
Ankylosing Spondylitis
Efficacy and Safety of Risedronate (Actonel), a Third Generation Bisphosphonate in Patients With Ankylosing Spondylitis: a Phase 2 Pilot Study
Randomized, controlled, double-blind, multicenter phase II study comparing risedronate 35mg (ActonelR 35mg weekly tablet) versus placebo in patients with active ankylosing spondylitis (AS) treated with standard first and…
- Trial name
- NCT01038011
- Testing
- drug treatment
- Where
- Switzerland
- Sponsor
- University of Zurich
Kidney Failure
Does Terlipressin Improve Renal Outcome After Liver Surgery
The investigators aim to address whether terlipressin improves the renal outcome after liver surgery. Therefore the investigators are planning to conduct a double-blinded randomized control trial.
- Trial name
- TIROL (NCT02368249)
- Testing
- Terlipressin
- Where
- Switzerland
- Sponsor
- University of Zurich
Pulmonary Arterial and Chronic Thromboembolic Pulmonary Hypertension
Effect of Long-term Oxygen Therapy on Exercise Capacity and Quality of Life in Patients With Pulmonary Arterial and Chronic Thromboembolic Pulmonary Hypertension
In this randomized-controlled, cross-over trial the investigators test the effect of long-term oxygen therapy (> 16h/day) given for 5 weeks with a wash-out period between phases of 2 weeks on exercise performance and quality of…
- Trial name
- NCT01884012
- Testing
- long term oxygen therapy
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University of Zurich
Effect of High Altitude
Effect of High Altitude Exposure, Acclimatization and Re-exposure on Lung Water Content by Ultrasound
Prospective interventional trial in lowlanders evaluating effect of acute exposure, acclimatization and re-exposure to high altitude.
- Trial name
- NCT02760186
- Testing
- Altitude Exposure
- Where
- Switzerland
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Cerebrospinal Fluid Leakage
Cerebrospinal Fluid Rhinorrhea After Functional Endoscopic Sinus Surgery
Sinus surgery is a common procedure. A potential complication is injuring the membranes of the brain. This can lead to leakage of brain fluid through the nose. We would like to estimate the incident rates of that complication.
- Trial name
- NCT02382692
- Where
- Switzerland
- Volunteers
- 31 people
- Sponsor
- University of Zurich
Peritoneal Cancer
Pathophysiology of Inflammation After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy
The purpose of this study is to assess the dynamics of inflammatory parameters in presence or absence of infectious complications after cytoreductive surgery with hyperthermic intraperitoneal chemotherapy.
- Trial name
- NCT02741167
- Testing
- CRS and HIPEC
- Where
- Switzerland
- Volunteers
- 90 people
- Sponsor
- University of Zurich
Cat Allergy
Evaluation of a New Self-assessed, Home-based Symptom Score in Cat Allergic Patients
In the last decades the prevalence of allergies has reached epidemic proportions. 10 to 15% of the population suffers from cat allergy.
- Trial name
- HypoScore-2 (NCT02959073)
- Testing
- Symptom Recording
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Growth and Development
Validation of a Smart Phone App to Non-invasively Measure the Size of Children
Smart phones are omnipresent. Apps exist to calculate size of medical equipment and doses of medication if a valid weight or age is entered. During emergency situations, these values are often unknown.
- Trial name
- NCT02805192
- Testing
- Size Measurement by a Smart phone App
- Where
- Switzerland
- Volunteers
- 627 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Myositis
Validation of Rehab Assessments in Myositis Patients
The aim of the study is to evaluate the psychometric properties (content and construct validity, reliability, measurements error, as well as possible floor and ceiling effects) of both the assessments MMT8 and the myositis…
- Trial name
- NCT03059394
- Testing
- Non intervention study
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- University of Zurich
Motor Activity
Virtual Reality Exercise on the Intensive Care Unit in Heart Patients
This project proposes the development and design of a motor intervention using a cognitive video game and describes the feasibility, safety and acceptability of virtual augmented video gaming device named Virtual Reality on the…
- Trial name
- VRICUGAMING (NCT02661230)
- Testing
- COGNIPLUS
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Hemispatial Neglect
Evaluating the Feasibility and Usability of Exergames in Stroke Patients With Visuo-spatial Neglect
The aim of this study is to evaluate the feasibility and usability of newly developed exergames on exploring the hemineglected space of left neglected stroke patients.
- Trial name
- NCT02353962
- Testing
- Neglect Exergames
- Where
- 2 sites in Switzerland
- Volunteers
- 7 people
- Sponsor
- University of Zurich
Cystic Fibrosis
Exercise and Oscillatory Positive Expiratory Pressure Therapy in Cystic Fibrosis
The investigators aim to compare a single bout of moderately intense cycling exercise incorporating Flutter® breathing maneuvers with a single bout of moderately intense cycling exercise alone on sputum viscoelasticity (primary…
- Trial name
- NCT02750722
- Testing
- Flutter®, No Flutter®
- Where
- 3 sites in Switzerland
- Volunteers
- 16 people
- Sponsor
- University of Zurich
Addison Disease, Hypoaldosteronism
Adrenal Function After Living Kidney Donation
The success of kidney transplantation is hampered by the shortage of organs. One attractive strategy is the use of kidneys from living donors.
- Trial name
- NCT00251836
- Testing
- Laparoscopic hand-assisted donor nephrectomy
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University of Zurich
Fistula;Rectal, Fistula; Rectouterine
Zurich Fistula Cohort Study
This is a pro- and retrospective cohort study to evaluate the natural history and outcome of various treatment options of patients with fistula.
- Conditions
- Fistula;Rectal, Fistula; Rectouterine, Fistula; Rectovesical, Fistulas Recto Vaginal
- Trial name
- NCT03003351
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University of Zurich
CT Perfusion and MRI Perfusion in Solid Tumors
PET/MRI Perfusion and CT Perfusion in Solid Tumors
Diagnostic comparison between PET/CT and PET/MRI with integrated perfusion measurement in CT and MR. Study aim is to gain knowledge about additional value of CT perfusion and MR perfusion in solid tumors concerning tumor…
- Trial name
- Perfusion (NCT02314962)
- Where
- Switzerland
- Volunteers
- 43 people
- Sponsor
- University of Zurich
Neoplasm Staging
Diagnostic Comparison of PET-magnetic Resonance and PET-CT in Patients With Oncologic Diseases
Diagnostic accuracy of PET/magnetic resonance and PET/CT will be compared concerning primary tumor, regional nodes, metastasis (TNM) staging and therapeutic influence.
- Trial name
- Workflow (NCT02316431)
- Where
- Switzerland
- Volunteers
- 142 people
- Sponsor
- University of Zurich
Mild Cognitive Impairment, Mild Dementia
Move for Your Mind - Pilot Trial
Move for your mind is a single blind, 3-arm randomized controlled clinical pilot trial. The study aims to test the effect of a weekly Dalcroze eurhythmics program (arm 1) and a home strength exercise program (arm 2) against…
- Conditions
- Mild Cognitive Impairment, Mild Dementia, Fall Prevention
- Trial name
- MFYM - P (NCT02279316)
- Testing
- Vi-De 3, Jaques-Dalcroze eurhythmics, Home exercise program
- Where
- Switzerland
- Volunteers
- 19 people
- Sponsor
- University of Zurich
Lung Cancer
The Role of Sedation Technique in EBUS-TBNA
There is a paucity of data concerning the impact of the sedation technique used for endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) on diagnostic accuracy.
- Trial name
- NCT02245295
- Testing
- Moderate Sedation for EBUS/TBNA, General anesthesia for EBUS/TBNA
- Where
- Switzerland
- Volunteers
- 232 people
- Sponsor
- University of Zurich
Heart Surgical Procedures
6-month Follow up After Sevoflurane Postconditioning
Retrospective analysis of a 6-month follow up within a randomised controlled study in cardiac surgery with pharmacological postconditioning (sedation on intensive care unit with sevoflurane)
- Trial name
- NCT02378168
- Testing
- no intervention; retrospective study
- Where
- 2 sites in Switzerland
- Volunteers
- 108 people
- Sponsor
- University of Zurich
Cardiac Arrest, Sudden, Heart Arrest
Influence of the Education in Layperson in Out of Hospital Resuscitation
Cardiac arrest occurs frequently and the outcome after out-of-hospital resuscitation is often fatal. Disturbing is that more than half of the surviving patients suffer from permanent impairment of cognitive functions, such…
- Trial name
- NCT02473679
- Where
- Switzerland
- Volunteers
- 1,662 people
- Sponsor
- University of Zurich
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