Clinical trials: sponsored by University of Zurich
Trauma, Inflammation
Transcriptomic Profiling in Severely Injured Patients
Discovery of differences in the host response in patients with systemic inflammation and sepsis, and identification of novel, specific markers by using a longitudinal clinico-transcriptomic approach.
- Conditions
- Trauma, Inflammation, Sepsis
- Trial name
- NCT02508272
- Where
- Switzerland
- Volunteers
- 115 people
- Sponsor
- University of Zurich
Vitamin D Deficiency
Effect of Vitamin D Treatment on Fatigue
Primary objective -Change in Fatigue Assesment Score (FAS) between the first visit (baseline) and 28 (+maximum 7) days after oral administration of 100 000 E vitamin D (Cholecalciferol).
- Trial name
- NCT02022475
- Testing
- Vitamin D
- Where
- Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Peripheral Nerve Injuries, Pain
Effect of Rufinamide on Chronic Postthoracotomy Pain Syndrome
The purpose of this study is to test if rufinamide has an effect on chronic neuropathic pain in patients with a post thoracotomy pain syndrome.
- Trial name
- RUFPTPS (NCT02095899)
- Testing
- Rufinamide
- Where
- Switzerland
- Sponsor
- University of Zurich
Healthy
Vestibular Pain Interactions
The goal is to establish the practical usefulness of vestibular stimulation for modulating pain perception and to describe the possible mechanisms that could underlie neural vestibular-somatosensory interactions.
- Trial name
- VPI (NCT02358954)
- Testing
- Quantitative sensory testing, CHEPS, 3D Turntable
- Where
- Switzerland
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Lung Cancer
Ultrathin Bronchoscopy for Solitary Pulmonary Nodules
The evaluation of solitary pulmonary nodules (SPN) requires a balance between procedure-related morbidity and diagnostic yield, particularly in areas where tuberculosis is endemic.
- Trial name
- Babyscope (NCT02490059)
- Testing
- bronchoscopy
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Zurich
Cat Allergy
Evaluation of a New Self-Assessed, Home-Based Symptom Score Test in Cat Allergic Patients
The purpose of this study is to better standardize the symptom recording of cat allergic persons under real-life conditions. A new self-assessed, home-based symptom score will be tested.
- Trial name
- NCT02399579
- Testing
- Provocation test
- Where
- Switzerland
- Volunteers
- 10 people
- Sponsor
- University of Zurich
Iron-Deficiency Anemia, Pregnancy
Different Iron Supplements for Prevention of Anemia in Pregnancy
Examination of iron supplements routinely used in pregnancy to compare these with one another regarding effectiveness in the prevention of iron deficiency.
- Trial name
- EDISA (NCT02487719)
- Testing
- Iron sulfate and Iron polymaltose for prevention of iron deficiency anemia
- Where
- Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Gastroesophageal Reflux, Dyspepsia
Effects of Diet on Reflux and Dyspepsia
Reflux and dyspeptic symptoms are common affecting 10-20% of the population on a regular basis. Reflux symptoms such as heartburn and regurgitation are caused by the return of acid or non-acid gastric contents into the esophagus.
- Trial name
- NCT02425553
- Testing
- Diet
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Heart Diseases
Transpulmonary Thermodilution Measurements in Patients With Heart Diseases
The purpose of this study is to examine the validation of the PiCCO (Pulse Contour Cardiac Output)-derived transpulmonary thermodilution technology in patients with heart diseases.
- Trial name
- NCT02035007
- Testing
- PiCCO Catheter (Pulsiocath 5F)
- Where
- Switzerland
- Volunteers
- 70 people
- Sponsor
- University of Zurich
Photosensitivity Disorders
Skin Aging in Renal Transplant Patients
Determination of collagen, pigment and haemoglobin content of sun exposed and sun protected skin by Siascopy. Immunocompromised patients (for more than seven years) compared to immunocompetent patients.
- Trial name
- NCT01776983
- Testing
- Photosensitivity under the influence of immunocomp
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University of Zurich
Hepatocellular Carcinoma, Intrahepatic Cholangiocarcinoma
Response of Hepatic Tumors to Radioembolization
The study enrolls patients with non-resectable or borderline resectable hepatocellular carcinoma (HCC), intraheaptic choalngiocarcinoma (IHCC) or colorectal cancer metastasis.
- Conditions
- Hepatocellular Carcinoma, Intrahepatic Cholangiocarcinoma, Liver Metastasis
- Trial name
- RESRAD (NCT01775280)
- Testing
- Injection of Ytttrium-90 microspheres into the hepatic artery
- Where
- Switzerland
- Sponsor
- University of Zurich
Liver Tumors Not Resectable in One Surgical Procedure
ALLPS VERSUS PVO Randomized Controlled Trial
This randomized phase II trial compares how well associating liver partition with portal vein ligation for staged hepatectomy (ALPPS) or portal vein occlusion (PVO) works in treating patients with liver cancer.
- Trial name
- ALPPS (NCT01775267)
- Testing
- Associating liver partition and portal vein ligation for staged hepatectomy, Portal vein embolization or ligation
- Where
- 3 sites in United States, Argentina and 1 more
- Volunteers
- 7 people
- Sponsor
- University of Zurich
Hyperkalemia
Clinical Decision Support System for Quality Assurance in Potassium-Increasing Drug-Drug-Interactions
To investigate the impact of reminders for serum potassium monitoring and of hyperkalemia alerts during potassium-increasing drug-drug-interactions.
- Trial name
- NCT02020317
- Testing
- decision support in potassium-inc. drug-drug-interactions
- Where
- Switzerland
- Volunteers
- 3,341 people
- Sponsor
- University of Zurich
Wasp Venom Allergic Patients
Performance of CAST (Cellular Antigen Stimulation Test) in Patients With Wasp Venom Allergy: Evaluation of Neutralizing IgG Subclasses
To determine which subclass of IgG in the serum of patients undergoing SIT against wasp venom is able to neutralize the allergen, and therefore to prevent a positive CAST
- Trial name
- NCT00794287
- Testing
- Taking blood samples
- Where
- Switzerland
- Sponsor
- University of Zurich
Low Back Pain
Lumbar Infiltration With Steroids - Effects on Pain Reduction
Questionnaire for patients who got a lumbar infiltration in our clinic. The patients will have to answer questions concerning their pain. (The lumbar infiltration itself is not part of this study)
- Trial name
- NCT01330875
- Testing
- survey
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- University of Zurich
Chronic Obstructive Pulmonary Disease
Is COPD a Risk Factor for Cardiovascular Disease?
Patients with chronic obstructive pulmonary disease suffer from significant cardiovascular morbidity and mortality. This study wants to determine whether chronic obstructive pulmonary disease might be a risk factor for coronary…
- Trial name
- NCT02162095
- Where
- Switzerland
- Volunteers
- 162 people
- Sponsor
- University of Zurich
Fasciitis, Plantar, Achillodynia
Extracorporeal Shock Wave Treatment - Can the Pain be Reduced?
Patients with Fascititis plantaris, Achillodynie, Periarthropathia humerosacpularis calcarea or Epikondylopathia humeri /radii get the shock wave therapy in our clinic as planned.
- Conditions
- Fasciitis, Plantar, Achillodynia, Periarthritis Calcarea, Epikondylopathia Humeri /Radii
- Trial name
- NCT01429883
- Where
- Switzerland
- Volunteers
- 36 people
- Sponsor
- University of Zurich
Calcinosis Cutis in Connective Tissue Disease
Calcinosis Cutis: Therapeutic Effects of Extracorporeal Shock Wave Therapy (ESWT)
Patients with calcinosis cutis due to connective tissue disease get a shock wave therapy. The shock wave therapy will be done in 3 sessions with one week interval.
- Trial name
- NCT01683500
- Testing
- shock wave therapy with Modulith SLK (Storz)
- Where
- Switzerland
- Volunteers
- 4 people
- Sponsor
- University of Zurich
Celiac Disease
Study for Identifying Optimal Simvastatin Formulation for Uniform Time to Maximum Plasma Concentration
The inter- and intra-variability in the pharmacokinetic parameters of different formulations and doses of simvastatin in healthy subjects and in subjects with celiac disease in remission will be evaluated.
- Trial name
- NCT01642862
- Testing
- Simvastatin
- Where
- Switzerland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Colorectal Cancer, Immune Landscape
Comprehensive Immune-landscape in Localized Colorectal Cancer
Surgery still remains the mainstay of treatment for localized colorectal cancer. However, nearly 30% of patients with localized colorectal cancer (stage II and stage III) will present with recurrence.
- Trial name
- NCT02138370
- Where
- Switzerland
- Volunteers
- 300 people
- Sponsor
- University of Zurich
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