Clinical trials: sponsored by University of Zurich
Leukemia, Infection
Optimized Radiological Diagnosis of Hepatic Candidiasis During the Treatment of Acute Leukemias
Hepatic candidiasis is a frequent complication in patients receiving intensive chemotherapy for acute leukemia. Hepatic lesions may be detected by computerized tomographic (CT) scans, but there is no standardized CT protocol for…
- Trial name
- NCT01207843
- Testing
- Imaging
- Where
- Switzerland
- Volunteers
- 88 people
- Sponsor
- University of Zurich
Allogeneic Stem Cell Transplantation
Caphosol® Versus State-of-the-art Mouthcare in Patients With Allogeneic Stem Cell Transplantation: a Randomized Controlled Study About the Efficacy of the Mouth Rinse Caphosol®
Randomized controlled study about the efficacy of the mouth rinse Caphosol in patients with allogeneic stem cell transplantation. 85% of the patients receive a severe oral mucositis due to their treatment.
- Trial name
- NCT01758562
- Testing
- Caphosol
- Where
- Switzerland
- Volunteers
- 72 people
- Sponsor
- University of Zurich
Developmental Dyslexia
Prediction and Intervention in Developmental Dyslexia
The long-term goal of this study is to improve prediction of poor reading outcome at preschool age by using a combination of behavioural and neuroimaging measures and to evaluate a specific computerized training program to…
- Trial name
- LEXI (NCT02217696)
- Testing
- Computerized reading training
- Where
- Switzerland
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Liver Neoplasms, Liver Regeneration
Registry of Major Liver Resections Including ALPPS and Other Liver Resections in Two Stages
Recently a new method of induce similar hypertrophy in the liver as is observed after hepatectomy has been described and was given the eponym "ALLPS".
- Trial name
- ALPPSREG (NCT01924741)
- Testing
- ALPPS
- Where
- Switzerland
- Volunteers
- 500 people
- Sponsor
- University of Zurich
Major Liver Surgery
Effects of Omega-3 Fatty Acids on Outcome After Major Liver Resection
To study the efficacy and safety of intravenous Omegaven™ (vs. Placebo) in reducing postoperative morbidity and mortality after major liver resection.
- Trial name
- NCT01884948
- Testing
- Omegaven™
- Where
- Switzerland
- Volunteers
- 258 people
- Sponsor
- University of Zurich
Fourth Cranial Nerve Palsy
Teeth and Jaw Misalignment in Patients Suffering From Congenital Fourth Cranial Nerve Palsy
Patients suffering from congenital fourth cranial nerve palsy may have misalignment of jaws as well as teeth due to head tilt in childhood.
- Trial name
- IVPareseZahn (NCT02149355)
- Testing
- teeth molding
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Optic Disc Swelling
Antiacne Medications Pseudotumor Cerebri
The exact incidence of optic disc swelling and idiopathic intracranial hypertension in patients using antiacne medication is not known so far.
- Trial name
- AAMPTC (NCT02149615)
- Testing
- Retinal nerve fibre layer measurement
- Where
- Switzerland
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Community-acquired Pneumonia
Delayed Antibiotic Treatment in Community-acquired Pneumococcal Pneumonia.
I. To investigate time measurement from emergency room admission to first antibiotic administration. II. To evaluate risk factors for prolonged time to first antibiotic administration. III.
- Trial name
- NCT01683487
- Testing
- Observation
- Where
- Switzerland
- Volunteers
- 122 people
- Sponsor
- University of Zurich
Fabry Disease
Pulmonary Involvement in Patients With Fabry Disease
The objective of this study is to investigate whether Agalsidase alpha, a drug commonly prescribed in patients with Fabry disease, is associated with improvement of the pulmonary involvement.
- Trial name
- NCT01632111
- Testing
- Lung function measurement
- Where
- Switzerland
- Volunteers
- 110 people
- Sponsor
- University of Zurich
Chest Pain
Usefulness of Chest Wall Tenderness as Bedside Test to Exclude Acute Coronary Syndrome in Different Demographic Groups
To determine the significance of a simple bedside clinical test (chest wall tenderness) to exclude myocardial ischemia in different demographic groups.
- Trial name
- NCT01724996
- Testing
- Clinical examination: chest wall tenderness
- Where
- Switzerland
- Volunteers
- 110 people
- Sponsor
- University of Zurich
Knee Osteoarthritis
Effect of Pre-surgery Neuromuscular Physiotherapy (PT)
Background: Osteoarthritis (OA) is a common degenerative condition of large weight-bearing joints, such as the hip and knee, as well as small hand joints.
- Trial name
- Omega (NCT00913575)
- Testing
- preoperative neuromuscular training, knee OA School
- Where
- Switzerland
- Volunteers
- 44 people
- Sponsor
- University of Zurich
Takotsubo Cardiomyopathy
International Takotsubo Registry (InterTAK Registry)
This is a multicenter, multinational, prospective and retrospective, observational study of patients with Takotsubo cardiomyopathy (TTC).
- Trial name
- InterTAK (NCT01947621)
- Where
- Switzerland
- Volunteers
- 4,000 people
- Sponsor
- University of Zurich
Healthy Men
Sleep, Breathing and Psychomotor Performance at Altitude: A Physiologic Study in Healthy Subjects
This study investigates the effect of altitude exposure on sleep, breathing and psychomotor performance in healthy subjects.
- Trial name
- NCT01130948
- Testing
- altitude exposure
- Where
- Switzerland
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Obstructive Sleep Apnea Syndrome
Treatment of Patients With the Obstructive Sleep Apnea Syndrome at Altitude
The purpose of the study is to investigate the effect of acetazolamide as a treatment for sleep related breathing disturbances in patients with the obstructive sleep apnea syndrome living at low altitude during a sojourn at…
- Trial name
- NCT00714740
- Testing
- acetazolamide
- Where
- Switzerland
- Volunteers
- 49 people
- Sponsor
- University of Zurich
Obstructive Sleep Apnea Syndrome
Continuous Positive Airway Pressure and Acetazolamide to Treat Sleep Apnea Syndrome Patients at Altitude
The purpose of the study is to investigate the effect of nasal continuous positive airway pressure in combination with acetazolamide as a treatment for sleep related breathing disturbances in patients with the obstructive sleep…
- Trial name
- NCT00928655
- Testing
- acetazolamide, nocturnal continuous positive airway pressure
- Where
- Switzerland
- Volunteers
- 51 people
- Sponsor
- University of Zurich
Skin Disease
Impact on UVB Narrow Band and UVA1 Therapy on Serum 25-hydroxyvitamin D Levels
We plan to investigate the serum elevation of 25(OH)D under UVB nb and UVA1 therapy, in order to determine the effect of these nowadays frequently used wavelengths for phototherapy on vitamin D plasma levels.
- Trial name
- NCT00910260
- Testing
- Blood analysis
- Where
- Switzerland
- Volunteers
- 116 people
- Sponsor
- University of Zurich
Acute Mountain Sickness
Acclimatization Mechanisms During Ascent to 7500m
The trial evaluates the role of ascent protocol on acute mountain sickness and cardio-respiratory physiology during an ascent to Muztagh Ata (7546m).
- Trial name
- NCT00603122
- Testing
- ascent protocol
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Zurich
High Altitude Pulmonary Hypertension, Sleep Apnea
Sleep Related Breathing Disturbances and High Altitude Pulmonary Hypertension in Kyrgyz Highlanders
High altitude pulmonary hypertension, a form of altitude illness that occurs in long-term residents at altitudes >2500 m, is characterized by dyspnea, hypoxemia, impaired exercise performance and hypertension in the pulmonary…
- Trial name
- NCT01621061
- Where
- Kyrgyzstan
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Lung Transplant Recipients, Diverticulitis
Epidemiology of Diverticulitis in Lung Transplant Recipients
The purpose of this study is to assess incidence, treatment modalities and outcome of complicated and uncomplicated diverticulitis in highly immunosuppressed lung transplant recipients (LTRs) in order to establish improved…
- Trial name
- NCT02132078
- Where
- Switzerland
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Traumatic Brain Injury, Coma
Optimized Therapy in Severe Traumatic Brain Injured Patients
Severe traumatic brain injury is associated with life-threatening and incapacitating secondary injury. Contemporary therapeutic interventions are aimed at preventing and treating secondary damage.
- Trial name
- NCT02130674
- Testing
- Dipeptiven
- Where
- Switzerland
- Volunteers
- 12 people
- Sponsor
- University of Zurich
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