Clinical trials: sponsored by University of Zurich
Critically Ill
ICG- Liver Test Versus New Biomarkers as Prognostic Markers in Critically Ill Patients
Comparison of ICG liver testing with copeptin and SAPS II score as prognostic markers in critically ill patients.
- Trial name
- Greenpep (NCT01126554)
- Where
- Switzerland
- Volunteers
- 110 people
- Sponsor
- University of Zurich
Patients Undergoing Elective Thoracic Surgery Requiring Obligatory Single-lung Ventilation During Surgery
Prospective, Randomized Clinical Trial Evaluating the ETView Double-Lumen Tube
No prospective randomized clinical trial assessed the performance of this new device in a clinical setting. Consequently the aim of this study is to determine clinical performance of this new device compared with conventional…
- Trial name
- NCT01807676
- Testing
- ET View Double Lumen Tube, conventional Double Lumen Tube
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Zurich
Birch Pollen Allergy
Comparison of the Influence of Different Skin Conditions on the Allergic Skin Reactivity to Epicutanous Allergen Exposure
It is an open-label physiological investigation of the allergic skin reactivity to epicutaneous allergen exposition in 20 allergic patients in two different skin conditions.
- Trial name
- NCT02074930
- Testing
- Microporation by P.L.E.A.S.E. Professional / Prick needle
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Zurich
End Stage Liver Disease
Transoesophageal Echocardiography in Liver Transplantation
Severe hypotension during reperfusion in liver transplantation is a frequent adverse event. Rare data exist so far about pathophysiology of this phenomenon.
- Trial name
- NCT00547924
- Testing
- Transoesophageal echocardiography
- Where
- Switzerland
- Volunteers
- 17 people
- Sponsor
- University of Zurich
Low Bone Mass in Anorexia Nervosa Patients
A Pilot Study to Evaluate the Effect of Forsteo (Teriparatide, 1-34-rh-PTH) in Anorexia Nervosa Patients With Low Bone Mineral Density and Increased Bone Fagility (FAN-Trial)
Study Title: A pilot study to evaluate the effect of Forsteo® (Teriparatide, 1-34 rh-PTH) in Anorexia Nervosa patients with low mineral density and increased bone fragility (FAN-Trial) Short Title/Study ID: FAN-Trial /…
- Trial name
- NCT01801397
- Testing
- osteoanabolic therapy
- Where
- 2 sites in Switzerland
- Volunteers
- 10 people
- Sponsor
- University of Zurich
Healthy Volunteers
Effects of Buprenorphine on Ulnar Nerve Motor Block
Recent reports showed that the opioid buprenorphine is a very potent sodium channel blocker. Buprenorphine not only exerts a strong antinociception, but also a long lasting antihyperalgesic effect.
- Trial name
- NCT00949299
- Testing
- buprenorphine
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Healthy Subjects
Effect of Oral Rufinamide and Oxcarbazepine on Nerve Excitability, Hyperalgesia, Allodynia and Flare Reaction Compared to Placebo. A Monocenter, Randomized, Double-blind, Cross-over Study
Untersuchungen über die Wirkmechanismen von Antiepileptika haben gezeigt, dass durch eine Blockierung von spannungsabhängigen Natrium-Kanälen im Nervensystem die Schmerzübertragung moduliert werden kann.
- Trial name
- NCT01212458
- Testing
- Rufinamid
- Where
- Switzerland
- Volunteers
- 24 people
- Sponsor
- University of Zurich
Infection
Colistin Pharmacokinetics in Continuous Renal Replacement Therapy
The blood concentration of the antibiotic colistin is determined in patients in whom kidney function is reduced such that a renal replacement therapy is needed.
- Trial name
- NCT02081560
- Testing
- Colistin
- Where
- Switzerland
- Volunteers
- 10 people
- Sponsor
- University of Zurich
Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Sirolimus (Rapamune®) for Autosomal Dominant Polycystic Kidney Disease (ADPKD)
The aim of our study is to investigate whether Rapamune used at a low dose (2 mg/d) retards cyst growth and slows renal functional deterioration in patients with ADPKD.
- Trial name
- NCT00346918
- Testing
- Sirolimus, Standard
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University of Zurich
Healthy Volunteers
Oxytocin, Couple Interaction and Wound Healing
effects of intranasal oxytocin and couple interaction on wound healing. Trial with medicinal product
- Trial name
- NCT01594775
- Testing
- Syntocinon (Oxytocin) nasal spray
- Where
- Switzerland
- Volunteers
- 160 people
- Sponsor
- University of Zurich
Diabetes Mellitus Type 1
Effects of XOMA 052 on Insulin Production in Type 1 Diabetes
To assess the effects of treatment with XOMA 052 on beta-cell function and insulin production in subjects with well-controlled Type 1 diabetes. The safety, tolerability, and pharmacokinetics (PK) of XOMA 052 will also be assessed.
- Trial name
- LATE STAGE (NCT01788033)
- Testing
- XOMA 052
- Where
- Switzerland
- Volunteers
- 22 people
- Sponsor
- University of Zurich
Health Behavior
Effects of High-intensity Interval Training in Combination With Side-alternating Whole-body Vibration
Investigation of the training effects following 8 weeks of high-intensity interval training (HIT)in combination with side-alternating whole-body vibration compared to conventional HIT or side-alternating whole-body vibration.
- Trial name
- NCT01875146
- Testing
- 4x4 min HIT, 4x4 min HIT + WBV (18 Hz), 4x4 min HIT + (30 Hz)
- Where
- Switzerland
- Volunteers
- 33 people
- Sponsor
- University of Zurich
Bacteraemia Post Debridement
PVP Iodine Effect on Post Debridement Bacteraemia
The study investigates the effect of supra- and subgingival rinsing of 10% PVP prior to ultrasonic debridement in patients with periodontitis (as compared to rinsing with water) in terms of post treatment bacteraemia.
- Trial name
- PJB 1 (NCT01647347)
- Testing
- Supra- and subgingival rinsing with 10% PVP-iodine, Water
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Patients With Paroxysmal Atrial Fibrillation
The Effect of Simulated Obstructive Apnoea and Hypopnoea on Heart Rhythm in Patients With Paroxysmal Atrial Fibrillation
In this randomised controlled cross-over study we will investigate whether intrathoracic pressure changes induced by simulated obstructive apnoea and hypopnoea trigger premature supraventricular and ventricular contractions as…
- Trial name
- NCT01796080
- Testing
- Mueller manoeuvre, Inspiratory threshold, Expiratory apnoea
- Where
- Switzerland
- Volunteers
- 45 people
- Sponsor
- University of Zurich
Obstructive Sleep Apnoea
Randomized-controlled Trial (RCT) on CPAP-withdrawal and Microvascular Function in OSA
Randomized controlled trial (therapeutic vs. placebo CPAP) including 46 patients with obstructive sleep apnea (OSA) to define the physiological effects of continuous positive airway pressure (CPAP) therapy withdrawal on…
- Trial name
- NCT01797653
- Testing
- CPAP therapy withdrawal, Continue CPAP treatment
- Where
- Switzerland
- Volunteers
- 45 people
- Sponsor
- University of Zurich
Infection as Complication of Medical Care
Early Reassessment of Intravenous Antiinfective Therapy Due to "Antiinfective Reminders" (AIR Study)
Switching from intravenous application of antiinfective agents to oral therapy is often performed late including high costs and risk of complications.
- Trial name
- AIR (NCT01499927)
- Testing
- electronic reminders
- Where
- Switzerland
- Volunteers
- 74,766 people
- Sponsor
- University of Zurich
Hypertension
CoCo: Colour Coded Blood Pressure Control
Insufficient blood pressure control is a frequent problem despite the existence of effective treatment. One of the causes is insufficient self-monitoring and a lack of adherence to therapy.
- Trial name
- CoCo (NCT01013467)
- Testing
- "CoCo" colour coded blood pressure control
- Where
- Switzerland
- Volunteers
- 121 people
- Sponsor
- University of Zurich
Aging, Vitamin Deficiency
Swiss Study on Vitamin D and Calcium in Nursing Homes
Residents of nursing homes are endangered by malnutrition and vitamin D deficiency. Our study checks compliance with Swiss federal recommendations on vitamin D and calcium supplementation among residents of a Swiss nursing home.
- Trial name
- NCT01653353
- Testing
- peer physician-applied recommendation to the physicians
- Where
- Switzerland
- Volunteers
- 71 people
- Sponsor
- University of Zurich
Spider Bite
Swiss Study on Spider Bites
About spider bites in Middle Europe, there are published only a dozen cases. The investigators suspect that they may be much more frequent than reflected by the literature analysis (but much less dangerous than thought by…
- Trial name
- SSSB (NCT01355744)
- Where
- Switzerland
- Volunteers
- 17 people
- Sponsor
- University of Zurich
Anal Fistula
Anal Fistula Plug Versus Endorectal Advancement Flap
The purpose of this study is to determine whether anal fistula plug or endorectal advancement flap is more successful in the treatment of anal fistulas and compared both procedures with regards to cost.
- Trial name
- AFPERAF (NCT01931371)
- Testing
- Anal Fistula Plug, Endorectal Advancement Flap
- Where
- Switzerland
- Volunteers
- 71 people
- Sponsor
- University of Zurich
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.