Clinical trials: sponsored by University of Zurich
Thoracic Surgery With One-lung Ventilation
One-lung Ventilation: Expression of Pulmonary Inflammatory Mediators
One-lung ventilation; organ protection; volatile anesthetics One-lung ventilation has become a common procedure for thoracoscopic surgery. Two hypothesis will be tested in this study: 1.
- Trial name
- NCT00515905
- Testing
- Sevoflurane/propofol
- Where
- Switzerland
- Volunteers
- 76 people
- Sponsor
- University of Zurich
Healthy Volunteers
Effect of Hyperoxemia on Platelet Function in Healthy Volunteers
Prospective, controlled, randomized crossover volunteer study to investigate the effect of hyperoxemia due to inhalation of oxygen (80% inspiratory fraction) via reservoir-face-mask on blood coagulation, especially platelet…
- Trial name
- NCT01057420
- Testing
- oxygen inhalation
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Hymenoptera Sting Allergy
Frequency of Hymenoptera-stings in Patients Under Allergen-Specific Immunotherapy (SIT)
In Switzerland, 3.5% of the population are suffering from hymenoptera venom allergy. The only causal treatment of hymenoptera alelrty is venom specific immunotherapy.
- Trial name
- ZU-HVA-001 (NCT00742794)
- Testing
- Observation
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- University of Zurich
Laparoscopy, Clinical Competence
Comparative Evaluation of Simulator Based and Traditional In-surgery Laparoscopic Camera Training's Efficiency in Novices
This prospective randomized study aims for determination whether focused simulator based laparoscopic camera training in novices can improve camera performance in an actual clinical situations in the same manner as traditional…
- Trial name
- NCT01092013
- Testing
- Training on laparoscopic simulator in skills lab, Training at actual laparoscopic surgery, Technical instruction
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Bacteremia
Daptomycin Pharmacokinetics in Continuous Veno-venous Hemodiafiltration
The purpose is to investigate daptomycin pharmacokinetics in critically ill patients with suspected or verified bacteremia with Gram-positive cocci undergoing combined continuous hemodiafiltration at a filtration rate of…
- Trial name
- NCT01171547
- Testing
- Daptomycin
- Where
- Switzerland
- Volunteers
- 15 people
- Sponsor
- University of Zurich
Chronic HCV Hepatitis C
A Phase 1b, Single Center, Clinical Study to Investigate the Safety and Biological Responses to Baminercept in Patients With Chronic HCV Hepatitis.
Erstes Safety Trial mit Baminercept in chronischen HCV Patienten. Untersuchung des potentiell antiviralen, antiinflammatorischen Effekts sowie Modulation der hepatischen Gen-Expression.
- Trial name
- NCT01164384
- Testing
- Baminercept
- Where
- Switzerland
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Zurich
Chronic Venous Insufficiency
Venous Pressure Measurement of the Great Saphenous Vein Using Controlled Compression Ultrasound in Healthy Persons and Patients With Chronic Venous Disease as a New Non Invasive Method for Investigation of the Pathophysiology in Primary Varicose Veins
Part I: Proof of concept trial to achieve normal venous pressure values under different provocation maneuvers in healthy persons Part II: Non invasive measurement of venous pressure under different provocation maneuvers in…
- Trial name
- NCT01000909
- Testing
- Ultrasound (venous pressure measurement)
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- University of Zurich
Renal Transplantation
Association of the Intrarenal Resistance Index (RI) of Transplanted Kidneys With Generalized Atherosclerosis
Cross sectional observational ultrasound study of transplanted kidneys and the carotid artery in consecutive recruited outpatients.
- Trial name
- NCT01001065
- Testing
- Vascular ultrasound
- Where
- Switzerland
- Volunteers
- 160 people
- Sponsor
- University of Zurich
Renal Insufficiency
Colour Coded Duplex Ultrasound of Native Arterio-venous Fistula for Haemodialysis With Venous Pressure Measurement Using Controlled Compression Ultrasound as a Predictor for Shunt Maturation in the Early Postoperative Phase
Prospective observational ultrasound study of native arterio-venous fistula for haemodialysis with venous pressure measurement using controlled compression ultrasound.
- Trial name
- NCT01001000
- Testing
- Ultrasound (Pressure measurement)
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Zurich
Healthy Participants
Effects of White Wine vs. Tea Intake During and an Alcoholic Digestive Following a High Fat, High Calorie Cheese Fondue Meal on Gastric Emptying and Abdominal Symptoms in Healthy Volunteers
Tradition holds that the intake of different drinks with a meal has an important influence on the digestion of food and postprandial symptoms such as fullness, bloating and satiety; however this assumption have never been…
- Trial name
- NCT00943696
- Testing
- Ingestion of white wine vs. tea during and an alco
- Where
- Switzerland
- Volunteers
- 12 people
- Sponsor
- University of Zurich
COPD
Predicting the Course of Chronic Obstructive Pulmonary Disease (COPD) in Primary Care
Background: COPD is a systemic illness; morbidity and mortality due to this disease are on the increase, and it has great impact on patients' lives. Most COPD patients are managed by general practitioners (GP).
- Trial name
- ICECOLDERIC (NCT00706602)
- Where
- Switzerland
- Volunteers
- 450 people
- Sponsor
- University of Zurich
Overactive Bladder Syndrome
Intravesical Injection of Botox for Treating Therapy Refractory Overactive Bladder in Females
The neurotoxin Botox (botulinum neurotoxin type A) is shown to be effective in the treatment of therapy refractory overactive bladder syndrome.
- Trial name
- NCT01042119
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- University of Zurich
Obstructive Sleep Apnea Syndrome
Study to Investigate Sleep Apnea Patients at Altitude
The purpose of the study is to investigate the effect of an altitude sojourn on patients with the obstructive sleep apnea syndrome
- Trial name
- NCT00514826
- Testing
- altitude exposure
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Zurich
Ureteral Calculi
Medical Expulsive Therapy of Single Distal Ureteral Stones
Current therapeutic options for ureteral stones include active intervention as well as conservative "watch and wait" approaches.
- Trial name
- NCT00831701
- Testing
- Tamsulosin
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University of Zurich
Survival, Renal Failure
Fluid Resuscitation With HES 200/0.5 10% in Severe Burn Injury
HES 200/0.5 10% is equal to ringers lactat solution.
- Trial name
- NCT01120730
- Testing
- fluid resuscitation
- Where
- Switzerland
- Volunteers
- 28 people
- Sponsor
- University of Zurich
Tumor
Neurologic and Neurophysiologic Assessment of Clinical Course in Patients With Intraspinal Processes
Patients included in the study are treated at the Klinik für Neurochirurgie USZ. The clinical course is documented at Paraplegikerzentrum Balgrist using validated diagnostic procedures (e.g. SCIM, ASIA, neurophysiology).
- Trial name
- NCT01105520
- Testing
- Diagnostic
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University of Zurich
Rheumatoid Arthritis
Effectiveness of Occupational Therapy in Patients With Rheumatoid Arthritis(RCT)
The purpose of the study is to compare the short- and long-term effectiveness of an individualized, resource-oriented joint protection intervention with the standard, problem-oriented joint protection intervention for patients…
- Trial name
- NCT00400868
- Testing
- psycho-educational Joint protection education
- Where
- 4 sites in Switzerland
- Volunteers
- 54 people
- Sponsor
- University of Zurich
Allergy to Cat Dander
Evaluation of Safety, Tolerability, Immunogenicity and Efficacy of a Novel Method in Specific Immunotherapy in Cat Allergic Patients: a Placebo Controlled Trial
This study is placebo controlled, double blind, randomised, two arm dose escalation of a new product for specific immunotherapy in cat allergic patients
- Trial name
- IVN-CAT-001B (NCT00718679)
- Testing
- IVN201
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- University of Zurich
Coronary Artery Disease
Pycnogenol and Endothelial Function in Coronary Artery Disease
Pycnogenol® is a proprietary bark extract of the French maritime pine tree (Pinus pinaster ssp. atlantica). Pycnogenol® has prevented pathologic symptoms such as chronic inflammation and increased platelet aggregation, a risk…
- Trial name
- NCT00641758
- Testing
- Pycnogenol
- Where
- Switzerland
- Volunteers
- 25 people
- Sponsor
- University of Zurich
Mental Stress
Effect of Mental Stress on Platelet Function
The aim of the project is to study the acute and chronic effect of mental stress on platelet adhesion and aggregation in two population composed of normal subjects at different ages
- Trial name
- NCT00538707
- Testing
- 2-minute Bondet test
- Where
- Switzerland
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Zurich
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