Clinical trials: sponsored by Uppsala University
Malnutrition
Nutritional Status Among Older Adults. Risk Factors and Consequences of Malnutrition
The aim of the study is to estimate the prevalence of malnutrition among older adults admitted to hospital and to analyse predictive factors for malnutrition.
- Trial name
- NCT01161342
- Volunteers
- 1,771 people
- Sponsor
- Uppsala University
Chemotherapy Induced Peripheral Neuropathy (CIPN)
Electrical Stimulation and Chemotherapy Induced Peripheral Neuropathy
Chemotherapy-induced peripheral neuropathy (CIPN) implies sensory or deficits pain, loss of motor functions and impaired proprioception which in turn may affect balance and fine motor skills.
- Trial name
- NCT02088996
- Testing
- longwave diathermy on high power and interferential therapy, longwave diathermy on low power
- Where
- Sweden
- Volunteers
- 70 people
- Sponsor
- Uppsala University
Neoplasms, Kidney Failure
Post-transplant Cancer Incidence and Survival in Patients With or Without Pre-transplant Cancer
Patients with previous malignancies have increasingly been accepted for renal transplantation. However, post-transplant malignancy risk and survival rates of these patients are unknown.
- Trial name
- NCT02491580
- Where
- Sweden
- Volunteers
- 2,370 people
- Sponsor
- Uppsala University
Obesity, Hormone Responses
Effect of Gastric Bypass Surgery on Brain Responses
After obesity surgery gastric bypass (GBP) patients usually lose more than 50% of its former preponderance in relative short time (~ 2 years).
- Conditions
- Obesity, Hormone Responses, Cognitive Health
- Trial name
- NCT01815216
- Testing
- Bariatric surgery, Brain activity in resting state, Memory performance
- Where
- Sweden
- Volunteers
- 48 people
- Sponsor
- Uppsala University
Cancer, Depression
Self-help Program Via Internet for Adolescents With Cancer
The overall aim is to evaluate the clinical efficacy and cost-effectiveness of a self-help program via internet aiming at preventing development and maintenance of cancer-related emotional distress among adolescents with cancer.
- Conditions
- Cancer, Depression, Anxiety
- Trial name
- U-CARE:TeenCan (NCT01510236)
- Testing
- Self-help program
- Where
- 6 sites in Sweden
- Sponsor
- Uppsala University
Insomnia, Quality of Life
Auricular Acupuncture and Cognitive Behavioral Therapy Treatment for Insomnia
"Auricular acupuncture and cognitive behavioral therapy in the context of insomnia and low dose dependence of benzodiazepine-like drugs and other sleep medicine with addiction risk" INTRODUCTION: Insomnia is a common health…
- Trial name
- NADA (NCT01765959)
- Testing
- Auricular acupuncture (AA), cognitive behavioral therapy (CBT)
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Anxiety Disorders
School-based Universal Prevention for Anxiety and Depression in Sweden: A Cluster-randomized Trial
Mental illness is a major health problem in children and young people, and there is evidence that mental illness is increasing among young people in the population.
- Trial name
- NCT02134730
- Testing
- FRIENDS for life
- Where
- Sweden
- Volunteers
- 695 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Colonic Diverticulitis
The Out-patient, Non Antibiotic Management of Patients With Acute Uncomplicated Colonic Diverticulitis
Previous multicentre study NCT 01008488 indicates that a patient with CT-proven uncomplicated diverticulitis has a very low risk (1.4%) of developing severe complications such as perforations or abscesses.
- Trial name
- P-VOD (NCT01515150)
- Where
- Sweden
- Volunteers
- 161 people
- Sponsor
- Uppsala University
Cancer of Kidney and Renal Pelvis, Cancer of Liver
Effects of Dexmedetomidine During Radiofrequency Ablation of Abdominal Tumours
The purpose of he study is to evaluate effects of dexmedetomidine on pain during radiofrequency ablation of liver and kidney tumours.
- Trial name
- NCT02016391
- Testing
- Dexmedetomidine
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Uppsala University Hospital
Breast Cancer, Skin Metastases
Electrochemotherapy For The Treatment Of Breast Cancer That Has Spread to the Skin
Electroporation combined with chemotherapy (ECT) has been shown to be an effective treatment for breast cancer that has spread to skin.
- Trial name
- NCT01479946
- Testing
- Electrochemotherapy
- Where
- Sweden
- Sponsor
- Uppsala University Hospital
Anesthesia
Assessment of Airways Mechanical Properties by FOT and LIR During Anesthesia
The aims of the present study are: 1. To evaluate the effect of the induction of anaesthesia and paralysis in terms of changes in oscillatory mechanics parameters 2.
- Trial name
- NCT01506284
- Testing
- Forced oscillatory technique (FOT) and laser interferometry (LIR).
- Where
- Sweden
- Volunteers
- 14 people
- Sponsor
- Uppsala University Hospital
Mechanical Ventilation
Thoraco-abdominal Volume Variations During Anesthesia Studied by OEP.
The aim of this study is to examine chest wall volume changes monitored by opto-electronic plethysmography during recovery from anesthesia and early postoperative period.
- Trial name
- NCT01474850
- Testing
- lung recruitment maneuver
- Where
- Sweden
- Volunteers
- 18 people
- Sponsor
- Uppsala University Hospital
Neuropathic Pain
Methylene Blue Intravenously and Chronic Neuropathic Pain
Aim of Investigation Methylene blue (MB) is a diaminophenothiazine with antioxidant, anti-inflammatory properties and with inhibitory effects on nitric oxide.
- Trial name
- NCT02303886
- Testing
- Methylene blue
- Volunteers
- 10 people
- Sponsor
- Uppsala University
Neuropathic Pain
Lidocaine and Neuroma Pain Related Modalities
Background Subanesthetics concentrations of lidocaine are able to produce a differential block of the ectopic discharges, but not propagation of impulses, suppressing differentially the associated neuropathic pain symptoms.
- Trial name
- NCT02300038
- Testing
- Lidocaine (Xylocaine), NaCl
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Dietary Supplements, Probiotics
Cognitive and Metabolic Effects of a Probiotic Supplement
To examine the cognitive and metabolic effects of a probiotic supplement that is readily and already available for purchase in public drug stores.
- Conditions
- Dietary Supplements, Probiotics, Metabolism, Food Preferences
- Trial name
- NCT02005003
- Testing
- Inhibitory task, Blood samples, Feces collection
- Where
- Sweden
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Gastrointestinal Motility Disorder, Disturbance of Salivary Secretion
Nitric Oxide Control of Migrating Motor Complex: L-NMMA Effects in Relation to Receptor Blockades
The aim is to elucidate how NO works in conjunction with other neurotransmitters to regulate the migrating motility complex (MMC).
- Trial name
- LNMMA (NCT02245165)
- Testing
- L-Nitro-Monomethyl-Arginine (LNMMA) 10 mg/kg IV, saline
- Where
- Sweden
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Iron Deficiency, Neonatal Hyperbilirubinemia
Early Versus Delayed Cord Clamping at Term: Outcomes in Swedish Infants
Delayed clamping of the umbilical cord might prevent or slow the onset of iron deficiency by increasing the infant's iron endowment at birth.
- Trial name
- NCT01245296
- Testing
- Timing of clamping the umbilical cord
- Where
- Sweden
- Volunteers
- 392 people, healthy volunteers welcome
- Sponsor
- Uppsala University
CABG, Valve Surgery
Effects of Deep Breathing Exercises Two Months After Cardiac Surgery
Hypothesis: Deep breathing exercises performed during the first two months after cardiac surgery, will improve pulmonary function and patient-perceived quality of recovery.
- Trial name
- NCT01282671
- Testing
- Breathing exercises
- Where
- 2 sites in Sweden
- Volunteers
- 357 people
- Sponsor
- Uppsala University
Peritoneal Carcinomatosis, Gastric Cancer
Neo-adjuvant Chemo + Peritonectomy + Hyperthermic Intraperitoneal Chemo in Peritoneal Carcinomatosis From Gastric Cancer
The aims of this study are to investigate whether multimodal treatment of peritoneal carcinomatosis from gastric cancer is feasible and to evaluate the clinical outcomes and clinical effectiveness of neoadjuvant systemic…
- Trial name
- NCT01379482
- Testing
- Multimodal treatment
- Where
- Sweden
- Volunteers
- 18 people
- Sponsor
- Uppsala University
Osteo Arthritis
Bone Forming at Prosthetic Surfaces. Fingerprint2
What is the intensity of F-PET uptake in healthy and osteo arthritic femur and acetabulum, compared to the uptake adjacent to four analyzed endoprosthetic components 1½ and 6 months after surgery?
- Trial name
- NCT01623687
- Testing
- Component for acetabulum (Regenerex RingLoc cup), Components for the acetabulum (Lubinus cross linked cup), Arthroplasty components are for the femur (Cemented Lubinus SP II stem)
- Where
- Sweden
- Volunteers
- 26 people
- Sponsor
- Uppsala University