Clinical trials: sponsored by Uppsala University
Breast Cancer, Breast Carcinoma in Situ
Oncologic, Cosmetic and Patient Reported Outcomes in Value-Based Breast Surgery (OnCoPRO Value)
The study aspires to provide outcomes on surgery, quality of life and time-to-event outcomes following the development and validation of a standardised surgical assessment tool in a shared decision-making framework for patients…
- Conditions
- Breast Cancer, Breast Carcinoma in Situ, Breast Cancer Invasive, Breast Asymmetry
- Trial name
- OncoPROValue-1 (NCT06401304)
- Where
- 3 sites in Australia, Sweden and 1 more
- Volunteers
- 1,200 people
- Sponsor
- Uppsala University
Breast Cancer, Chemotherapy Effect
Delayed SLND for Patients With Breast Cancer Undergoing Primary Systemic Treatment
The goal of this study was to assess the feasibility of SLND by superparamagnetic iron oxide nanoparticles (SPIO) in patients with early breast cancer planned for primary systemic therapy (PST) and whether this is affected by the…
- Conditions
- Breast Cancer, Chemotherapy Effect, Sentinel Lymph Node
- Trial name
- MagNeo (NCT05985551)
- Testing
- SLND or TAD by the magnetic technique (SPIO)
- Where
- Sweden
- Volunteers
- 114 people
- Sponsor
- Uppsala University
Catheter Complications
Reduction of Mechanical IV Complication Using a New Medical Device
Peripheral intravenous catheters are necessary for in-hospital medical treatment. Malfunction due to occlusion or dislodgement is common, and increases the burden on health care.
- Trial name
- ReLink (NCT05814887)
- Testing
- ReLink
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Uppsala University Hospital
Sepsis, Septic Shock
Health Related Quality of Life After Intensive Care for Sepsis, a National Cohort Study.
The study aims to map the health-related quality of life (HRQoL) after intensive care for Sepsis with the hypothesis that it will be lower than that in the general population.
- Conditions
- Sepsis, Septic Shock, Sepsis, Severe
- Trial name
- NCT06368336
- Volunteers
- 210,484 people
- Sponsor
- Uppsala University Hospital
Obstructive Sleep Apnea, Sleep Disorder
Validation of Pediatric Sleep Questionnaire on a Swedish Cohort
This study is aimed to validate the questionnaire called Pediatric Sleep Questionnaire on a Swedish cohort of children from 18 months to 15 years old with obstructive sleep disordered breathing.
- Conditions
- Obstructive Sleep Apnea, Sleep Disorder, Sleep Disorders in Children, Obstructive Sleep Apnea of Child
- Trial name
- NCT06367400
- Testing
- Pediatric Sleep Questionnaire
- Where
- Sweden
- Volunteers
- 520 people
- Sponsor
- Uppsala University
Hamstring Tendon Injury
The Proximal Hamstring Avulsion Clinical Trial - Operative or Nonoperative Treatment
The purpose of this study is to provide reliable evidence on how to best treat proximal hamstrings avulsions, and our primary aim is to compare the reported outcome of patients treated non-operatively with patients treated with…
- Trial name
- PHACT (NCT03311997)
- Testing
- Surgical reattachment of hamstring tendons
- Where
- 10 sites in Norway, Sweden
- Volunteers
- 216 people
- Sponsor
- Uppsala University
Pain
Pharmacology and Non-pharmacology Approaches in Reducing Children's Pain and Fear During Painful Procedures
This study Will contribute in the knowledge of pediatric nurses during painful procedures such venipuncture
- Trial name
- NCT06326125
- Testing
- TICK-B, TKTX-Cream, TICK-B and TKTX-C
- Where
- Iraq
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Perioperative Complication
A Pilot Study of the Effects of 4 vs 3 Hours of Preoperative Fasting in Breast-feeding Infants
In the new guideline from ESAIC breast-feeding should be encouraged until 3 hours before anesthesia. This recommendation was based mainly on gastric emptying studies in neonates with small sample sizes and single center…
- Trial name
- BMRCT (NCT05573165)
- Testing
- 3 hours of preoperative fasting for breast milk, 4 hours of preoperative fasting for breast milk
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Uppsala University Hospital
Spinal Fractures
Uppsala Study on Odontoid Fracture Treatment in the Elderly
A multicenter randomized controlled trial is performed in Sweden (Uppsala, Malmo and Stockholm) comparing surgery with posterior C1-C2 fusion and conservative treatment with a rigid collar.
- Trial name
- USOFT (NCT02789774)
- Testing
- Posterior fusion C1-C2, Rigid cervical collar
- Where
- 2 sites in Sweden
- Volunteers
- 50 people
- Sponsor
- Uppsala University
Chronic Widespread Pain, Sleep Disturbance
Sleep Disturbances and Chronic Widespread Pain
Chronic widespread pain (CWP), defined as long-lasting pain in multiple body regions, has a prevalence of 10-14% in Europe and is associated with other physical symptoms such as fatigue and cognitive problems.
- Trial name
- POSEIDON (NCT03908905)
- Testing
- Polysomnography
- Where
- Sweden
- Volunteers
- 96 people
- Sponsor
- Uppsala University
Hypersomnia, Idiopathic
Idiopathic Hypersomnia
Idiopathic hypersomnia (IH) is characterized by non-restoring night-time sleep, excessive daytime sleepiness, sleep inertia, impaired cognitive functioning and autonomic symptoms.
- Trial name
- IDAHO (NCT05150977)
- Testing
- Polysomnography
- Where
- Sweden
- Volunteers
- 69 people
- Sponsor
- Uppsala University
Complex Regional Pain Syndromes, Chronic Pain
Treatment of Complex Regional Pain Syndrome, a Long-term Follow-up
Complex regional pain syndrome, CRPS, is an uncommon but often very disabling chronic pain syndrome characterized by, beside pain: sensory disturbances, peripheral autonomic changes and inflammatory features.
- Trial name
- TORNADO (NCT04597866)
- Testing
- Multimodal rehabilitation
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Uppsala University
Behavior Problem, Social Skills
Inclusive Positive Behaviour Supports
Background: While positive school climate is important for students' well-being and mental health, school personnel may experience challenges in creating a nurturing school climate.
- Trial name
- IBIS (NCT06270914)
- Testing
- Inclusive Positive Behavior Interventions and Supports
- Where
- Sweden
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Pain, Fear of Pain
Effectiveness of TKTX Cream on Pain and Fear in Children During Venipuncture: A Randomized Controlled Trial
Venipuncture, the process of obtaining blood samples for diagnostic purposes, is a common medical procedure performed worldwide. However, it can be associated with varying levels of pain and discomfort for patients.
- Conditions
- Pain, Fear of Pain, Venipuncture Site Numbness
- Trial name
- NCT05957718
- Testing
- TKTX cream
- Where
- Iraq
- Volunteers
- 88 people
- Sponsor
- Uppsala University
Caregivers, Head and Neck Cancer
Feasibility of Internet Based Support (Carer eSupport) for Informal Caregivers of Patients With Head and Neck Cancer
Informal caregivers to patients with head and neck cancer report that they are unprepared for caregiving, that they experience a high caregiver burden and a deteriorated health.
- Conditions
- Caregivers, Head and Neck Cancer, Feasibility Study
- Trial name
- NCT05028452
- Testing
- Internet based support
- Where
- 4 sites in Sweden
- Volunteers
- 32 people
- Sponsor
- Uppsala University
Violence Prevention Intervention Evaluation Among Youth
Adolescent Consent & Sexual Violence: A School Intervention Evaluation
Since 2015, Uppsala Tjej- och Transjour has run school sessions for secondary school pupils in Uppsala municipality, from year 9 to year 2.
- Trial name
- NCT06132074
- Testing
- School sessions on consent, reciprocity and sexual violence
- Where
- Sweden
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Obstructive Sleep Apnea
Benefits of Telemedicine in CPAP Treatment
Continuous positive airway pressure (CPAP) is the first choice of treatment for moderate to severe obstructive sleep apnea syndrome (OSAS).
- Trial name
- NCT03202602
- Testing
- Telemonitoring of CPAP treatment, Standard care
- Where
- Sweden
- Volunteers
- 216 people
- Sponsor
- Uppsala University
Severe Obesity
Comorbidity After Gastric Bypass
To evaluate effect on comorbid disease and weight loss in the long-term (>five years) after Roux-en-Y gastric bypass (RYGB) surgery for severe obesity.
- Trial name
- NCT02710786
- Testing
- Gastric bypass
- Where
- Sweden
- Volunteers
- 25,000 people
- Sponsor
- Uppsala University
Breast Cancer, Colorectal Cancer
Physical Training and Cancer-a Multicenter Clinical Trial
Excessive tiredness (fatigue) is a common problem in cancer patients and can affect quality of life negatively. There is limited knowledge about the physical mechanisms that cause fatigue, and there is no medical treatment.
- Conditions
- Breast Cancer, Colorectal Cancer, Prostate Cancer
- Trial name
- Phys-Can (NCT02473003)
- Testing
- high intensity exercise, low/medium intensity exercise, Behavioral medicine strategies
- Volunteers
- 600 people
- Sponsor
- Uppsala University
Compulsory Psychiatric Care Act, Psychosis
Psychological Treatment in Psychiatric Inpatient Care
This study aims to investigate the effect of a brief psychotherapeutic treatment intervention based on ACT, aimed specifically at the vulnerable group of patients in psychiatric 24-hour care treated according to LPT.
- Conditions
- Compulsory Psychiatric Care Act, Psychosis, Acceptance & Commitment Therapy, Psychiatric Hospitalization
- Trial name
- NCT06012981
- Testing
- ACT
- Where
- Sweden
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Uppsala University