Clinical trials: sponsored by Virginia Commonwealth University
Weight Gain
Impact of a LCD on Metabolic Inflexibility and Cardiovascular Risk in Liver Transplant Patients
This study is looking to see how a 6-month low carbohydrate diet can affect the body's ability to use energy in addition to the affects it has on the heart and blood vessel health.
- Trial name
- NCT04145427
- Testing
- Control, LCD
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Virginia Commonwealth University
Stress
Bundle Consent and Expectation Setting in Pediatric Intensive Care Unit
The purpose of this research study is to find out about how obtaining consent for procedures in the PICU affects parental/caregiver stress.
- Trial name
- NCT04697173
- Testing
- Single consent
- Where
- United States
- Volunteers
- 333 people
- Sponsor
- Virginia Commonwealth University
Glioblastoma, Recurrent Adult Brain Neoplasm
Sorafenib, Valproic Acid, and Sildenafil in Treating Patients With Recurrent High-Grade Glioma
The purpose of this research study is to test the safety, tolerability, and effectiveness of the combination of three drugs, sorafenib (Nexavar®), valproic acid (Depakote®), and sildenafil (Viagra®), when used to treat high-grade…
- Conditions
- Glioblastoma, Recurrent Adult Brain Neoplasm, Malignant Glioma, WHO Grade III Glioma
- Trial name
- NCT01817751
- Testing
- sorafenib tosylate, valproic acid, sildenafil citrate
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Virginia Commonwealth University
Emotion Regulation
Effects and Mechanisms of Smartphone-Based Stress Management Training on Well-Being in College Students
Studying can be a difficult time, and some students can find it challenging to deal with stress. This research project at Virginia Commonwealth University aims to understand how two different online stress management training…
- Trial name
- NCT05518656
- Testing
- Experimental intervention, Comparison intervention
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Obesity, Heart Failure With Normal Ejection Fraction
Unsaturated Fatty Acids to Improve Cardiorespiratory Fitness in Obesity and HFpEF
This study is designed to evaluate the effects of a diet rich in unsaturated fatty acids (UFA)-also known as 'healthy fats'-in patients with obesity and heart failure with preserved ejection fraction (HFpEF) on dietary…
- Trial name
- UFA-Preserved2 (NCT03966755)
- Testing
- UFA dietary recommendations
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Virginia Commonwealth University
Thyroid Goiter, Hypothyroidism
Energy Metabolism in Thyroidectomized Patients
The purpose of this research study is to measure the changes in energy metabolism (how the body burns energy), cardiovascular function (heart function), and lipid metabolism (cholesterol break down and building) before and after…
- Conditions
- Thyroid Goiter, Hypothyroidism, Thyroid Cancer
- Trial name
- NCT04782856
- Testing
- Levothyroxine, Liothyronine
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Virginia Commonwealth University
Prostate Cancer, Education
Feasibility Study: Educational Genetic Test Video
Assess whether introducing an educational video regarding the benefits, risks, and limitations of genetic testing affects prostate cancer patients' decisional conflict regarding receiving germline genetic testing.
- Trial name
- NCT06166758
- Testing
- Educational Video
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Virginia Commonwealth University
Emotions
Effects of Smartphone-Based Stress Reduction Training on Social Relations
The purpose of this research study is to find out how two different online stress reduction training programs affect people's daily experiences and social relations.
- Trial name
- NCT05730270
- Testing
- Stress reduction program 1, Stress reduction program 2
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Virginia Commonwealth University
Heart Diseases
Fasting Versus Non-fasting on Outcomes and Satisfaction Prior to Cardiac Catheterization
Moderate sedation is used in the catheterization laboratory relieve the anxiety and discomfort associated with access and other aspects of the procedure.
- Trial name
- CALORI (NPO) (NCT05851872)
- Testing
- Coronary angiogram, Right heart catheterization
- Where
- United States
- Volunteers
- 169 people
- Sponsor
- Virginia Commonwealth University
Healthy
The Effect of Brain Anatomy on the Efficacy of Brain Stimulation Therapy
The purpose of this research study is to determine whether brain anatomy impacts the efficacy of transcranial magnetic stimulation (TMS) which is a form of non-invasive brain stimulation.
- Trial name
- NCT04586387
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Chronic Obstructive Pulmonary Disease
Improving Cardiovascular Health in Patients With Chronic Obstructive Pulmonary Disease
Researchers have found a link between chronic obstructive pulmonary disease (COPD) and heart disease; however, a link is all they have found.
- Trial name
- NCT03819517
- Testing
- Resveratrol
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Loneliness, Depression
A Pilot Study to Examine the Impact of a Therapy Dog Intervention on Loneliness and Related Health Outcomes in Vulnerable Populations
The purpose of this research study is to test whether an animal-assisted interaction (AAI) intervention is better than conversation with another person or treatment as usual for improving mood, anxiety, loneliness, quality of…
- Conditions
- Loneliness, Depression, Anxiety, Quality of Life
- Trial name
- NCT05089201
- Testing
- Animal-assisted interaction, Conversational control
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Virginia Commonwealth University
Anesthesia
Use of Stable Airway Management Device in Monitored Anesthesia Care
The aim of this study is to determine if the Stable Airway Management device (SAM) is safe in maintaining the airway in a stable, non-obstructing position during anesthetic cases requiring monitored anesthesia care (MAC).
- Trial name
- NCT05087979
- Testing
- Stable airway management (SAM) device
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Virginia Commonwealth University
COVID-19, Lung Injury, Acute
SAFEty Study of Early Infusion of Vitamin C for Treatment of Novel Coronavirus Acute Lung Injury (SAFE EVICT CORONA-ALI)
This study will evaluate the safety of a 96-hour intravenous vitamin C infusion protocol (50 mg/kg every 6 hours) in patients with hypoxemia and suspected COVID-19.
- Conditions
- COVID-19, Lung Injury, Acute, Kidney Injury
- Trial name
- NCT04344184
- Testing
- L-ascorbic acid
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Virginia Commonwealth University
Cardiac Surgery, Post-operative Cognitive Dysfunction
Active Temperature Management After Cardiac Surgery and Its Effect on Postoperative Cognitive Dysfunction
This study will assess the effect of active postoperative temperature management and its effect on the cognitive function in patients following coronary artery bypass graft (CABG) surgery to determine if active postoperative…
- Conditions
- Cardiac Surgery, Post-operative Cognitive Dysfunction, Fever
- Trial name
- NCT03947671
- Testing
- Rapr Rounds Hyper/Hypothermia Wraps, Acetaminophen
- Where
- United States
- Sponsor
- Virginia Commonwealth University
Depression
Self-Management of Chronic Depressive Symptoms in Pregnancy
This study will provide information about the feasibility, acceptability, and preliminary effects of a biobehavioral self-management approach for perinatal depressive symptoms.
- Trial name
- NCT02953990
- Testing
- MOMS Program
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Virginia Commonwealth University
Hypertension
Chronobiology of Meal Timing: Effects on Vascular and Renal Function
The purpose of this study us to investigate the effects of mistimed eating on blood pressure, kidney function and vascular function.
- Trial name
- NCT05987566
- Testing
- Morning meal challenge, Evening meal challenge
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Virginia Commonwealth University
Mood, Cancer Brain
Managing Cancer and Living Meaningfully
The purpose of this study is to pilot test an empirically supported psychotherapeutic intervention, Managing Cancer and Living Meaningfully (CALM).
- Trial name
- CALM (NCT04646213)
- Testing
- Managing Cancer and Living Meaningfully (CALM) Therapy
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Virginia Commonwealth University
Parkinson Disease
Safety and Efficacy of State-of-the-Art Exoskeleton Technology to Improve Mobility in Parkinson's Disease
The purpose of this study is to test the safety and efficacy of using of a portable exoskeleton for walking training in persons with Parkinson's disease that have gait mobility problems and/or postural instability.
- Trial name
- NCT04587193
- Testing
- Robotic-assist gait training device
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Virginia Commonwealth University
Cancer of Colon, Cancer of Rectum
Colorectal Health Research Champions
The purpose of the Colorectal Health Research Champions program is to provide accurate and reliable colorectal health cancer information that they can share within their communities to encourage cancer prevention, screening, and…
- Trial name
- NCT04812743
- Testing
- Colorectal Health Research Champions
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University