Clinical trials: sponsored by Virginia Commonwealth University
Smoking
Researching the Youth Smoking Experience
The primary hypothesis of this pilot study is that dependence can be prevented in adolescents who smoke, but who are not yet dependent.
- Trial name
- NCT00156702
- Testing
- Feedback and Motivational Interviewing, Smoking Prevention Video
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
H1N1 Influenza, Seasonal Influenza
Characteristics and Outcomes of Intensive Care Unit Patients Admitted With Novel H1N1 Influenza or Seasonal Influenza
The purpose of this research study is to collect information on problems that patients with the novel H1N1 influenza and/or the seasonal influenza experience. Novel H1N1 flu is also called the swine flu.
- Trial name
- NCT01011582
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Virginia Commonwealth University
Smoking
Brief Computerized Feedback for Smokers in Recovery
The purpose of this research study is to find out more about smokers in recovery from addiction to alcohol/other drugs, and to evaluate a brief computerized smoking behavior feedback session.
- Trial name
- NCT01325727
- Testing
- Brief computerized feedback, Resources only (control)
- Where
- United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Prevention
An Interactive Preventive Health Record (IPHR) to Promote Patient-Centered Preventive Care
Americans only receive 50% of indicated preventive services. We hypothesize that an interactive preventive health record (IPHR) will increase the delivery of recommended screening tests, immunizations, and counseling.
- Trial name
- NCT00589173
- Testing
- Interactive Preventive Health Record (IPHR), "Standard" preventive care
- Where
- United States
- Volunteers
- 5,500 people
- Sponsor
- Virginia Commonwealth University
Unhealthy Diet, Exercise, Smoking, and Alcohol Use
A Comprehensive Practice-Friendly Model for Promoting Healthy Behaviors
Using an electronic health record to link the resources of primary care practices and community programs will help patients to improve their diet and exercise, quit smoking, and moderate their drinking.
- Trial name
- NCT00292968
- Testing
- Computer based care, Telephone counseling, Group visits
- Where
- United States
- Volunteers
- 5,670 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Drug Addiction, Smoking Cessation
Examining the Effect of the Nicotine Patch in Male and Female Smokers - 3
Treatment studies have demonstrated that current smoking cessation techniques are less effective for women. The purpose of this study is to determine the role that gender plays in the effectiveness of nicotine replacement…
- Trial name
- NCT00390559
- Testing
- nicotine transdermal system, Nicotine containing cigarette
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Obstructive Sleep Apnea
Study of Effects of Sutures on Results of Palate Surgery for Obstructive Sleep Apnea
In this study we will examine whether suture repair of the palate, or roof of mouth, has any effect on results of palate surgery performed for treatment of obstructive sleep apnea.
- Trial name
- NCT00205543
- Testing
- uvulopalatopharyngoplasty with or without sutures
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Virginia Commonwealth University
Preeclampsia
Clinical Trial of a COX-2 Inhibitor for the Treatment of Women With Preeclampsia
Preeclampsia is a hypertensive disorder of pregnancy and a leading cause of fetal and maternal morbidity and mortality. Recent findings indicate preeclampsia is an inflammatory disorder associated with increased expression of…
- Trial name
- NCT00442676
- Testing
- Celecoxib
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Quality of Treatment Services
Organizational Factors Influencing Practice Improvement in Community Based Care
Purpose of the Study: The Richmond Behavioral Health Authority's Substance Abuse Services Division and Virginia Commonwealth University's Institute for Drug and Alcohol Studies are working on an important research study to…
- Trial name
- NCT00746577
- Testing
- Organizational change to improve the implementation of evidence-based practices.
- Where
- United States
- Volunteers
- 910 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Sepsis, Alcoholism
Relationship Between Alcohol Use Disorders and Cortisol Levels in Patients With Sepsis
Patients with alcohol use disorders are often cared for in the intensive care unit (ICU). We estimate that close to half of the patients we care for in our ICU have alcohol use disorders.
- Trial name
- NCT00615862
- Testing
- Observational study; no interventions
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Virginia Commonwealth University
Dental Implantation
Clinical Investigation of Mandibular Implant Overdenture
The purpose of this study is to compare the effectiveness of three variable dental implant attachment methodologies in conjunction with lower dental-implant retained/supported complete overdenture treatment.
- Trial name
- NCT00066014
- Testing
- Implant Overdenture Treatment
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Virginia Commonwealth University
Breast Cancer
Pilot Study of 18F Fluoropaclitaxel (FPAC)
Multidrug resistance (MDR) is a cause of treatment failure in many cancer patients. MDR refers to a phenotype whereby a tumor is resistant to a large number of natural chemotherapeutic drugs.
- Trial name
- NCT00572598
- Testing
- 4- [F-18] fluoropaclitaxel
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Acute Coronary Syndromes, Coronary Artery Disease
Computed Tomographic Coronary Angiography for Acute Chest Pain Evaluation
The purpose of this study is to evaluate whether 64-slice Computed Tomographic coronary angiography is useful for rapid diagnosis or exclusion of significant coronary artery disease in patients who present to the Emergency…
- Trial name
- EDCCTA (NCT00615719)
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Virginia Commonwealth University
Nausea, Vomiting
Intra-abdominal at Cesarean Section: A Randomized Controlled Trial
The purpose of this study is to determine if intra-abdominal irrigation at the time of cesarean delivery increased maternal GI discomfort without affecting infection rates.
- Trial name
- NCT01479712
- Testing
- Normal Saline Irrigation
- Where
- United States
- Volunteers
- 263 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Cerebrovascular Trauma, Neurohormones
Observational Endothelin and Markers of Cellular Apoptosis In CSF Head Injury
The goal of this study is to answer the following questions: What is the time course of the expected changes in endothelin levels during the first two weeks after injury and how does this relate to outcome? What is the relation…
- Conditions
- Cerebrovascular Trauma, Neurohormones, Cellular Apoptosis, Endothelin System
- Trial name
- Endothelin (NCT00498498)
- Where
- 11 sites in United States, Germany and 2 more
- Volunteers
- 51 people
- Sponsor
- Virginia Commonwealth University
Polycystic Ovary Syndrome
Oral Administration of DCI to Women With PCOS
To determine if oral DCI administration to women with PCOS increases the total DCI content in urine and blood, and, if so, if that change is accompanied by i) an increase in DCI-IPG release in blood (as determined by bioactivity)…
- Trial name
- PCOS (NCT00497653)
- Testing
- DCI
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Virginia Commonwealth University
Sickle Cell Disease
Phase 1 Study of Zoledronic Acid in Sickle Cell Disease
The long-term goal of this study is to learn if Zoledronic Acid can prevent or reduce pain in sickle cell disease. The goal of this study is to learn about the safety of Zoledronic Acid in persons with sickle cell disease who…
- Trial name
- NCT00639392
- Testing
- Zoledronic Acid
- Where
- United States
- Sponsor
- Virginia Commonwealth University
Fibromyalgia
Study to Explore the Relationships Among Immunity and Stress and the Symptoms of Fatigue, Pain, and Mood Following Guided Imagery in Women With Fibromyalgia
This project will be the first known to explore the relationships among immunity and stress and the symptoms of fatigue, pain, and mood following guided imagery in women with fibromyalgia.
- Trial name
- NCT01453647
- Testing
- Guided Imagery
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Virginia Commonwealth University
Coronary Artery Disease
Conservation of Red Cell Mass , Oxygen Supply and Demand in Cardiac Surgery
Fifty patients will be enrolled into the study. The purpose of the study is to investigate the relevance of Hct levels in determining need for transfusion during operations employing bypass as well as to test the hypothesis that…
- Trial name
- NCT00660608
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Esophageal Varices
Beta Blockers Versus Variceal Band Ligation and Beta Blockers for Primary Prophylaxis of Variceal Bleeding
Patients with scarring of the liver (cirrhosis) and portal hypertension (elevated blood pressure in the liver vasculature) can develop esophageal varices (dilated veins). These have an increased risk of bleeding each year.
- Trial name
- NCT00409084
- Testing
- endoscopic variceal band ligation
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Virginia Commonwealth University