Clinical trials: sponsored by Xijing Hospital
Hyperuricemia
Effect of Increased Daily Water Intake in Patients With Hyperuricemia
The purpose of this study is to explore the clinical effect of reducing uric acid by drinking water, and provide scientific evidence and clinical guidance for reducing uric acid by drinking water.
- Trial name
- NCT06315543
- Testing
- Drink water
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Xijing Hospital
Insomnia Disorder
A Clinical Study of Theta Burst Stimulation (cTBS) in the Treatment of Insomnia Disorder Targeting the Dentate Nucleus of the Cerebellum
Insomnia disorder (ID) is a significant public health problem worldwide, with nearly a third of the general population experiencing insomnia symptoms in their lifetime.
- Trial name
- NCT05992285
- Testing
- transcranial magnetic stimulation
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Xijing Hospital
Siewert Type II Adenocarcinoma of Esophagogastric Junction
Comparison of Different Operations for Siewert Type II Adenocarcinoma of Esophagogastric Junction
The incidence of esophagogastric junction has been increasing in recent years, and surgery is an important method for the treatment of adenoma at the esophagogastric junction.
- Trial name
- NCT05356520
- Testing
- Endoscopy Ivor-lewis, Laparoscopic transabdominal enlarged gastrectomy
- Where
- China
- Volunteers
- 212 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Premature Ejaculation, Anxiety
Development and Validation of an Anxiety Disorder Prediction Model for Premature Ejaculation Patients
Background: Premature ejaculation (PE) is a common sexual dysfunction that can significantly impact the quality of life and psychological well-being of affected individuals.
- Trial name
- NCT06677814
- Where
- 2 sites in China
- Volunteers
- 700 people
- Sponsor
- Xijing Hospital
Stress, Psychological, Sleep Initiation and Maintenance Disorders
Precision Transcranial Magnetic Stimulation for Patients With Post-stress Sleep Disorders
This is a randomized, double-blind controlled study that recruited patients with insomnia problems after suffering a stressful event to undergo individualized transcranial magnetic stimulation
- Conditions
- Stress, Psychological, Sleep Initiation and Maintenance Disorders, Transcranial Magnetic Stimulation
- Trial name
- NCT06653959
- Testing
- active Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xijing Hospital
Transcranial Magnetic Stimulation, Alzheimer Disease
Cerebellar ITBS Mode Transcranial Magnetic Stimulation for the Treatment of Alzheimer's Disease
Study the therapeutic effect and potential neural mechanisms of cerebellar iTBS mode transcranial magnetic stimulation on Alzheimer's disease patients through MRI and EEG.
- Conditions
- Transcranial Magnetic Stimulation, Alzheimer Disease, Magnetic Resonance Imaging, Electroencephalogram
- Trial name
- NCT06379100
- Testing
- transcranial magnetic stimulation
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Xijing Hospital
Cognition
The Study on Effects of Acute Exposure to High Altitude Hypoxia on Cognitive Function in Lowlanders
The purpose of this study is to investigate the impact of rapid elevation to 3,800 meters on the cognitive function of low-altitude residents through a plateau field and plain control study, and explore the objective indicators…
- Trial name
- NCT05411185
- Where
- China
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Neoadjuvant Chemotherapy, Sintilimab
Efficacy and Safety of Neoadjuvant Sintilimab Plus FLOT Versus Sintilimab Plus SOX Phase II Clinical Trial for Patients With Locally Advanced Gastric Cancer
This study aims to investigate the efficacy and safety of Sintilimab combined with FOLT versus Sintilimab combined with SOX in patients with locally advanced gastric cancer.
- Conditions
- Neoadjuvant Chemotherapy, Sintilimab, Locally Advanced Gastric Cancer
- Trial name
- NCT06459921
- Testing
- SOX+Sintilimab, FLOT+Sintilimab
- Volunteers
- 200 people
- Sponsor
- Xijing Hospital
Depression
Efficacy and Mechanism of rTMS on the Symptoms of Pleasure Deficit in Adolescent Depression
(1) Primary objective: to collect data on the score of pleasure deficit scale before and after repetitive transcranial magnetic stimulation treatment in adolescent depressed patients, and to verify its efficacy and safety in…
- Trial name
- NCT06580249
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- China
- Volunteers
- 44 people
- Sponsor
- Xijing Hospital
Degenerative Spinal Disease, Elderly Patients
Preoperative Risk Evaluation and Per ERAS Intervention in the Chinese Elderly Patients Underwent Spinal Fusion Surgery
This study aims to evaluate the value of preoperative risk factor evaulation combined with perioperative ERAS measures in improving the clinical prognosis of elderly patients undergo the spinal fusion.
- Conditions
- Degenerative Spinal Disease, Elderly Patients, Spinal Fusion Acquired
- Trial name
- NCT06607081
- Testing
- Multidisciplinary Preoperative Risk Evaluation and the Corresponded Pre ERAS intervention
- Where
- 2 sites in China
- Volunteers
- 5,000 people
- Sponsor
- Xijing Hospital
Gastric Intestinal Metaplasia
Metformin Efficacy and Safety for Gastric Intestinal Metaplasia
Gastric intestinal metaplasia significantly increases the risk of gastric cancer. Metformin, a biguanide, which is widely used for treating diabetes mellitus, has recently been suggested to have a suppressive effect on…
- Trial name
- NCT05288153
- Testing
- Metformin, Folate
- Where
- 2 sites in China
- Volunteers
- 140 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Esophageal Cancer
Efficacy and Safety of Penpulimab Combined With Anlotinib and Chemotherapy
This study is a two arm, randomized, prospective, multicenter study on the perioperative treatment of locally advanced resectable esophageal cancer with penpulimab combined with anlotinib hydrochloride and chemotherapy.
- Trial name
- EASOPCWAAC (NCT06586242)
- Testing
- Penpulimab;Anlotinib;albumin paclitaxel;oxaliplatin;lobaplatin
- Where
- China
- Volunteers
- 194 people
- Sponsor
- Xijing Hospital
Gastric Cancer
The Efficacy and Safety of Benmelstobart for GC/EGC
The goal of this clinical trial is to evaluate the major pathological response (MPR) rate of locally advanced gastric cancer / gastroesophageal junction cancer treated with bemosumab combined with antiangiogenic drugs and…
- Trial name
- EASOBFGE (NCT06603974)
- Testing
- surgery, Benmelstobart, tegafur
- Volunteers
- 48 people
- Sponsor
- Xijing Hospital
Helicobacter Pylori Infection, Chronic Gastritis
Study on the Efficacy and Safety of Berberine, Minocycline, Esomeprazole, and Colloidal Bismuth Quadruple Therapy in the Initial Treatment of Helicobacter Pylori.
The aim of this study is to evaluate the efficacy and safety of a quadruple therapy consisting of berberine hydrochloride, minocycline, esomeprazole, and colloidal bismuth tartrate for the first phase eradication of Helicobacter…
- Trial name
- NCT06603688
- Testing
- esomeprazole, Bismuth, Amoxicillin
- Where
- China
- Volunteers
- 548 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital of Digestive Diseases
Non-alcoholic Fatty Liver Disease
the Role of plin5 in the Development of Nonalcoholic Fatty Liver Disease.
To further clarify the role of sequence polymorphism in patatin-like phospholipid domain containing protein 3 in the development of nonalcoholic fatty liver disease.
- Trial name
- NCT04104282
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Xijing Hospital
Prostate Cancer
Neoadjuvant Therapy of Darolutamide Plus ADT for High Risk Prostate Cancer
The purpose of this study is to determine if treatment with Darolutamide plus androgen deprivation therapy (ADT) before radical prostatectomy (RP) with pelvic lymph node dissection (pLND) in participants with high-risk localized…
- Trial name
- NCT06575257
- Testing
- Darolutamide, Goserelin 3.6 mg
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Xijing Hospital
Esophageal Squamous Cell Carcinoma
High-concentration Small-volume Versus Low-concentration Large-volume Iodine Solution for Esophageal Chromoendoscopy
This clinical trial aims to test the participants' tolerance for different concentration iodine solutions during esophageal chromoendoscopy.
- Trial name
- NCT06063941
- Testing
- 1% Lugol's iodine solution, 5% Lugol's iodine solution
- Where
- 5 sites in China
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital of Digestive Diseases
Transcranial Electrical Stimulation, Temporal Lobe Epilepsy
Transcranial Electrical Stimulation Targeting the Cerebellum for the Treatment of Refractory Temporal Lobe Epilepsy
Study the therapeutic effect and potential neural mechanisms of transcranial electrical stimulation targeting the cerebellum for the treatment of refractory temporal lobe epilepsy through MRI and EEG.
- Conditions
- Transcranial Electrical Stimulation, Temporal Lobe Epilepsy, Magnetic Resonance Imaging, Electroencephalogram
- Trial name
- NCT06558890
- Testing
- Transcranial Alternating Current Stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xijing Hospital
Acute Kidney Injury
Correlation Between Preoperative NT-proBNP and Postoperative AKI
Accurate preoperative AKI risk prediction is of great significance for improving patient outcomes. The use of preoperative NT-proBNP can provide a more precise assessment of the body's fluid load status, guide intraoperative and…
- Trial name
- NCT06145347
- Where
- China
- Volunteers
- 629 people
- Sponsor
- Xijing Hospital
the Eradication Rates of Helicobacter Pylori
Standard or Short-course Vonoprazan Non-bismuth Triple Therapy or High-dose Dual Therapy Versus Rabeprazole-bismuth Quadruple Therapy for Primary Helicobacter Pylori Eradication
The goal of this clinical trial is to compare eradication rates of Helicobacter pylori in patients aged 18-70 years with first infection.
- Trial name
- NCT06168214
- Testing
- Rabeprazloe+bismuth+amoxicillin+clarithromycin, Vonoprazan+amoxicillin+clarithromycin 14 days, Vonoprazan+amoxicillin+clarithromycin 7 days
- Where
- China
- Volunteers
- 1,404 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital of Digestive Diseases