Clinical trials: sponsored by Xijing Hospital
Melanoma
Allogeneic Gammadelta T Cells Combined With Interferon-α1b or PD-1 Monoclonal Antibody in Stage III-IV Amenable to Surgical Resection Melanoma
The purpose of this study is to evaluate the efficacy and safety of allogeneic γδ T cells combined with recombinant human interferon-α1b (IFN-α1b) or PD-1 monoclonal antibody in neoadjuvant treatment of patients with Stage III-IV…
- Trial name
- NCT06212388
- Testing
- Ex-vivo expanded allogeneic γδ T cells, Recombinant human interferon α1b, Pembrolizumab
- Volunteers
- 10 people
- Sponsor
- Xijing Hospital
Prostatic Neoplasms, Metastases
68Ga-PSMA PET in the Prostate Cancer
Efficacy of 68Ga PSMA PET / CT in the diagnosis of lymph node metastasis in patients with prostate cancer: a single center prospective randomized controlled trial.
- Conditions
- Prostatic Neoplasms, Metastases, PSMA-PET
- Trial name
- NCT04967001
- Testing
- PSMA PET
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
De Novo Stenosis, Coronary Artery Disease
Paclitaxel-Coated Balloon Versus Zotarolimus-Eluting Stent for Treatment of De Novo Coronary Artery Lesions
Coronary restenosis has been one of the main reasons affecting the prognosis of patients with coronary artery disease (CAD) after percutaneous coronary intervention (PCI).
- Conditions
- De Novo Stenosis, Coronary Artery Disease, Percutaneous Coronary Intervention
- Trial name
- CAGE-FREEIII (NCT05209412)
- Testing
- Lepu Paclitaxel coated balloon, Resolute Integrity Zotarolimus eluting stents, Aspirin
- Where
- China
- Volunteers
- 370 people
- Sponsor
- Xijing Hospital
COVID-19, Infections
Survey of COVID-19 Infection
Using online questionnaires, we will obtain data regarding COVID-19 infection and treatment, including incidence rate, hospitalization rate, severity of the infection, medications, mortality rate, etc, in both hospital and…
- Trial name
- NCT05706064
- Where
- China
- Volunteers
- 200,000 people
- Sponsor
- Xijing Hospital
Bullous Pemphigoid
Retrospective Study of the Effects of Sub-pathologic Phenotypes of BP on Clinical Management and Prognosis
Bullous pemphigoid (BP) is a chronic autoimmune subepidermal blistering disease primarily affecting the elderly with a significant risk of mortality and morbidity.
- Trial name
- BP (NCT06213909)
- Testing
- This is a retrospective analysis of health data from inpatient record, no intervention was designed
- Where
- China
- Volunteers
- 318 people
- Sponsor
- Xijing Hospital
PTSD
Precise Transcranial Magnetic Stimulation for Post-traumatic Stress Disorder
The purpose of this study is to investigate the efficacy and safety of repetitive transcranial magnetic stimulation under precise localization for post-traumatic stress disorder
- Trial name
- NCT05544110
- Testing
- Active transcranial magnetic stimulation
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Xijing Hospital
Adebrelimab, Esophageal Cancer
Perioperative Adebrelimab and Chemotherapy in Esophageal and Esophagogastric Junction Carcinoma
The goal of this prospective, open-label, single-center clinical study is to learn about the efficacy and safety of aderbelimab combined with chemotherapy in the perioperative treatment of esophageal and esophagogastric junction…
- Conditions
- Adebrelimab, Esophageal Cancer, Perioperative Period
- Trial name
- NCT06198465
- Testing
- adebrelimab,Paclitaxel,Lobaplatin,Fluorouracil
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Xijing Hospital
Generalized Anxiety Disorder
Transcutaneous Vagus Nerve Stimulation for Generalized Anxiety Disorder
This is a randomized, double-blind, parallel-controlled study of patients with generalized anxiety disorder, who will be randomly assigned to either drug-combined transcutaneous vagus nerve stimulation (tVNS) group or…
- Trial name
- NCT06134323
- Testing
- medication-combined transcutaneous vagus nerve stimulation
- Where
- 2 sites in China
- Volunteers
- 82 people
- Sponsor
- Xijing Hospital
Attention Deficit Hyperactivity Disorder
Visual Focused Play Intervention for Children With ADHD
This is a single-center, randomized, double-blind, sham-controlled study that will recruit children with attention deficit hyperactivity disorder and randomly assign them to a test group and a control group.
- Trial name
- NCT06140979
- Testing
- Playing the game, Watching the gameplay video
- Volunteers
- 40 people
- Sponsor
- Xijing Hospital
Antiplatelet Drug, Acute Coronary Syndrome
1-month DAPT Plus 5-month Ticagrelor Monotherapy Versus 12-month DAPT in Patients With Drug-coated Balloon
Drug-Coated Balloon (DCB) angioplasty is similar to plain old balloon angioplasty procedurally, but there is an anti-proliferative medication paclitaxel coated to the balloon.
- Conditions
- Antiplatelet Drug, Acute Coronary Syndrome, Angioplasty, Balloon
- Trial name
- CAGEFREEII (NCT04971356)
- Testing
- Aspirin 100mg for 1-month (immediately after PCI), Ticagrelor 90mg for 6-month (immediately after PCI), Aspirin 100mg for 6-month (6-month post PCI)
- Where
- China
- Volunteers
- 1,948 people
- Sponsor
- Xijing Hospital
Squamous Cell Carcinoma of Head and Neck, Neoadjuvant Therapy
PABLIXIMAB as Neoadjuvant Therapy for Head and Neck Squamous-cell Carcinoma
The goal of this clinical trial is to learn about the efficacy and safety of pablizumab combined with neoadjuvant chemotherapy in patients with locally advanced head and neck squamous cell carcinoma.
- Conditions
- Squamous Cell Carcinoma of Head and Neck, Neoadjuvant Therapy, Immunotherapy
- Trial name
- NCT06125223
- Volunteers
- 45 people
- Sponsor
- Xijing Hospital
Autologous Fat Graft Harvesting, SVF-gel Preparation and Filling, CO2 Fractional Laser Treatment by Using Acupulse Device
Comparison of SVF-gel Filling and CO2 Fractional Laser on Atrophic Acne Scar Treatment
Background Adipose extracellular matrix/stromal vascular fraction gel（SVF-gel）, which contains adipose-derived stem cells, endothelial cells, smooth muscle cells, pericytes, and other cell components.
- Trial name
- NCT06116162
- Testing
- SVF-gel Filling and CO2 fractional laser
- Where
- 2 sites in China
- Volunteers
- 18 people
- Sponsor
- Xijing Hospital
Knee Osteoarthritis
Treatment of Knee Osteoarthritis (KOA) by Injection of Autologous Adipose-derived Vascular Matrix Components (SVF) Into Joint Cavity
The purpose of this study was to analyze and study the efficacy and safety of autologous adipose-derived vascular matrix components (SVF) in patients with knee osteoarthritis before and after treatment through clinical…
- Trial name
- NCT06109220
- Testing
- Stromal vascular fraction,SVF
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Newly-diagnosed Ph+ Acute Lymphoblastic Leukemia
Olverembatinib Plus Venetoclax and Dexamethasone for Treatment-naïve Ph+ Acute Lymphoblastic Leukemia
The purpose of this study is to explore the efficacy and safety of the OVD chemotherapy-free regimen (Olverembatinib, venetoclax and dexamethasone) in patients with newly-diagnosed Ph+ALL.
- Trial name
- NCT06082934
- Testing
- Olverembatinib plus venetoclax and dexamethasone
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Xijing Hospital
Psoriasis
Hypertension, Antihypertensive Medication Use, and Risk of Psoriasis
The influences of hypertension and antihypertensive medication on psoriasis have been long discussed. Given the limited and inconsistent evidence available, there is a need to further explore and clarify the relationship between…
- Trial name
- NCT06075394
- Where
- China
- Volunteers
- 9,294 people
- Sponsor
- Xijing Hospital
Digestive Disease
A Population-based, Multicenter Cohort Study of Combined Screening for Gastrointestinal Tumors
To establish combined gastroenteroscopy screening and follow-up management for gastrointestinal tumors, explore and evaluate the feasibility and health economic benefits of combined screening for esophagus, stomach and colorectal…
- Trial name
- NCT05996458
- Testing
- Gastroenteroscopy；Risk factor investigation; FIT-HP;RNF180 and SEPTIN9 gene methylation test, Risk factor investigation;
- Where
- China
- Volunteers
- 84,000 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Multimodal Analgesia, Cesarean Section
TAP Using Dexmedetomidine and Ropivacaine for Cesarean Section Analgesia
To evaluate the effect of dexmedetomidine as an adjuvant of ropivacaine in the TAP block on cesarean section parturients under multimodal analgesia, optimize the multimodal analgesia program for cesarean section, and guide…
- Trial name
- NCT05700045
- Testing
- Dexmedetomidine
- Where
- 2 sites in China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Perioperative Neurocognitive Disorders
The Reliability and Validity of Perioperative Cognitive Test Network Platform for Monitoring Neurocognitive Changes
This study aimed to analyze the reliability and validity of the results of the new designed perioperative cognitive test network platform, and to judge the reliability and scientific nature of the perioperative cognitive test.
- Trial name
- NCT06028568
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Hypertrophic Cardiomyopathy, Arrhythmia
Impact of Liwen Procedure in Obstructive Hypertrophic Cardiomyopathy on Arrhythmias
The goal of this observational study is to learn about the occurrence of various arrhythmias ( tachyarrhythmia and bradyarrhythmia ) during or after Percutaneous Intramyocardial Septal Radiofrequency Ablation.
- Trial name
- NCT06031519
- Testing
- Percutaneous Intramyocardial Septal Radiofrequency Ablation for hypertrophic obstructive cardiomyopathy (Liwen Procedure)
- Where
- China
- Volunteers
- 350 people
- Sponsor
- Xijing Hospital
Gastric Cancer, Precancerous Lesion of Digestive Tract
The Role of Extracellular DNA (ecDNA) in the Occurrence and Development of Gastric
ECDNA is almost non-existent in normal cells, but exists in nearly half of human cancer cells, indicating that studying such abnormal DNA is of great significance for our understanding of tumor formation and evolution.
- Conditions
- Gastric Cancer, Precancerous Lesion of Digestive Tract, Extrachromosomal DNA
- Trial name
- NCT05956847
- Testing
- gastroscopy
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital