Clinical trials: sponsored by Xijing Hospital
Hypertrophic Obstructive Cardiomyopathy
The Safety and Influencing Factors of Liwen Procedure in The Treatment of Hypertrophic Cardiomyopathy
Liwen procedure is generally safe and effective in treating hypertrophic cardiomyopathy, but a small proportion of patients have complications after the operation.
- Trial name
- NCT06003478
- Testing
- Percutaneous Intramyocardial Septal Radiofrequency Ablation for hypertrophic obstructive cardiomyopathy (Liwen Procedure)
- Where
- China
- Volunteers
- 486 people
- Sponsor
- Xijing Hospital
Helicobacter Pylori
Association of Oral Helicobacter Pylori Infection With Gastric Helicobacter Pylori Infection
The aim of this study was to investigate the association between oral Helicobacter pylori infection and gastric Helicobacter pylori infection.
- Trial name
- NCT05790512
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital of Digestive Diseases
Metabolism Disorder, Glucose, Metabolism Disorder, Lipid
Correlation of Glucose and Lipid Metabolism Levels With Vitiligo
The goal of this observational study is to compare serum glucose and lipid metabolism levels between health volunteers and vitiligo patients.
- Conditions
- Metabolism Disorder, Glucose, Metabolism Disorder, Lipid, Vitiligo
- Trial name
- NCT05968235
- Testing
- Collecting blood samples
- Where
- China
- Volunteers
- 963 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Atrial Fibrillation
Low-dose NOAC Versus GDMT After LAAO
The increased risk of Atrial fibrillation (AF) regarding thromboembolic stroke is predominantly due to the formation and embolization of clots from within the left atrial appendage (LAA).
- Trial name
- RECORD-III (NCT05960721)
- Testing
- Rivaroxaban 15mg, Aspirin 100mg, Clopidogrel 75mg
- Where
- China
- Volunteers
- 4,220 people
- Sponsor
- Xijing Hospital
Epileptic Seizures Related to Drugs
The Efficacy and Safety of Minocycline in the Treatment of Drug-resistant Epilepsy in NORSE Patients
Exploring the efficacy and safety of oral minocycline combined with antiepileptic drugs in the treatment of drug-resistant epilepsy in NORSE patients, obtaining preliminary research data, and providing evidence and data support…
- Trial name
- NCT05958069
- Testing
- minocycline
- Where
- China
- Volunteers
- 25 people
- Sponsor
- Xijing Hospital
Osteoporosis, Spinal Fusion
Recombinant Human Bone Morphogenetic Protein-2(rhBMP-2) in Patients With Osteoporosis After Lumbar Fusion
rhBMP-2 has been used to promote spinal fusion. Despite potential risk of complications, satisfied results could be obtained with low dose of rhBMP-2.
- Trial name
- NCT05911477
- Testing
- RhBMP-2
- Volunteers
- 76 people
- Sponsor
- Xijing Hospital
Ulcerative Colitis Chronic Moderate, Ulcerative Colitis Chronic Severe
Autologous Platelet-rich Plasma (PRP) and Thrombin Coagulum for the Topical Treatment of Rectal Mucosal Ulcers
Ulcerative colitis (UC) is a chronic persistent inflammatory disease. The lesions are mainly confined to the large intestine and continuously affect the rectum and part or all of the colon.
- Conditions
- Ulcerative Colitis Chronic Moderate, Ulcerative Colitis Chronic Severe, Rectal Ulcer
- Trial name
- NCT05912712
- Testing
- Autologous Platelet-rich Plasma (PRP) and Thrombin Coagulum Treatment, Autologous Platelet-poor Plasma (PPP) and Thrombin Coagulum Treatment, Mesalazine Suppository Treatment
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xijing Hospital of Digestive Diseases
GIST
Exploring the Molecular Mechanism Based on KIT Mutation
Imatinib remains suboptimal for recurrence/metastasis and unresectable GIST response rates. With the maturity of genomics and metabolomics, people gradually realize the role of gut microbiota in tumor therapy.
- Trial name
- EMMBKM (NCT05895942)
- Testing
- Imatinib
- Where
- China
- Volunteers
- 190 people
- Sponsor
- Xijing Hospital
Acne Atrophica
The Efficacy and Safety of Dezocine Pretreatment for Pain Relief in Acne Scar Treatment of Fractional CO2 Laser
The Efficacy and Safety of Dezocine Pretreatment for Pain Relief in Acne Scar Treatment of Fractional CO2 Laser
- Trial name
- NCT05861063
- Testing
- Fractional CO2 laser, Dezocine
- Where
- China
- Volunteers
- 105 people
- Sponsor
- Xijing Hospital
Sexual Dysfunction
Sexual Dysfunction After Renal Transplantation
A questionnaire will be send to kidney transplant recipients to investigate characteristics of them and their sexual function, all participants in the survey are anonymous and voluntary, then analyse these characteristics.
- Trial name
- NCT05856929
- Testing
- no Intervention
- Where
- 2 sites in China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Striae Distensae
Efficacy and Safety of Polylevolactic Acid Injection Combined With 1565nm Non-ablative Fractional Laser in the Treatment of Striae Distensae
1. Striae distensae (SD), also known as stretch marks, are common, permanent dermal lesions that can be symptomatic and are considered aesthetically undesirable; thus, they pose a significant psychosocial and therapeutic…
- Trial name
- NCT05827913
- Testing
- Polylevolactic Acid Injection, 1565nm Non-ablative Fractional Laser, Polylevolactic Acid Injection combined with 1565nm Non-ablative Fractional Laser
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Xijing Hospital
Androgenic Alopecia
A Clinical Observation of 1565nm Non-ablative Fractional Laser in the Treatment of Androgenic Alopecia
1. Androgenic alopecia (AGA) is a clinically common non cicatricial, progressive hair follicle microminiaturization disorder that begins in puberty or after puberty.
- Trial name
- NCT05827991
- Testing
- 1565nm Non-ablative Fractional Laser, 5% minoxidil external use, 1565nm Non-ablative Fractional Laser combined with 5% minoxidil
- Where
- China
- Volunteers
- 75 people
- Sponsor
- Xijing Hospital
Suicidal Ideation, Depression
Neuroimaging Guided and Robot-assisted rTMS for Suicidal Ideation of Depression
There is relatively insufficient evidence on whether rTMS can improve suicidal ideation in depressive patients. And existing studies have been inconsistent in the treatment of depressive suicidal thoughts.
- Trial name
- NCT04653337
- Testing
- Robot-assisted accelerated iTBS-1800 combined with serotonin-norepinephrine reuptake inhibitors(SNRIs), Robot-assisted accelerated iTBS-600 combined with serotonin-norepinephrine reuptake inhibitors(SNRIs)
- Where
- China
- Volunteers
- 56 people
- Sponsor
- Xijing Hospital
Gastric Cancer
An Exploratory Study of Immunotherapy Combined With Anlotinib and Chemotherapy in Perioperative Treatment of LAGC
1. Main objective: to evaluate the pathological complete response (pCR) of gastric cancer after local advanced COVID-19 infection by two kinds of immunotherapy combined with Anlotinib Hydrochloride Capsules and neoadjuvant…
- Trial name
- NCT05800080
- Testing
- Penpulimab combined with Anlotinib Hydrochloride Capsules and chemotherapy;Cadonilimab combined with Anlotinib Hydrochloride Capsules and chemotherapy
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Xijing Hospital
Coronary Disease
Electroacupuncture in Reducing the Dose of Analgesic in Patients Undergoing Off-pump Coronary Artery Bypass Grafting
A prospective, multiple-center, double-blinded, randomized, controlled clinical study to evaluate the antalgic effects between distal-proximal acupoints combination and regional acupoints combination stimulated with…
- Trial name
- NCT02443220
- Testing
- TEAS (transcutaneous electric acupoint stimulation), TEAS
- Where
- China
- Volunteers
- 315 people
- Sponsor
- Xijing Hospital
Primary Biliary Cirrhosis
Fenofibrate in Combination With Ursodeoxycholic Acid in Primary Biliary Cirrhosis
Ursodeoxycholic acid (UDCA) has been the only treatment for primary biliary cirrhosis (PBC) approved by US and European drug administrations.
- Trial name
- NCT02823353
- Testing
- Fenofibrate, UDCA
- Where
- China
- Volunteers
- 117 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Neoplasms
Clinical on the Safety and Efficacy of Fosaprepitant Dimeglumine for Injection in the Prevention of CINV.
To evaluate the safety of Fosaprepitant Dimeglumine Injection for the prevention of nausea and vomiting caused by tumor chemotherapy drugs, analyze the characteristics of the applicable population and clinical medication of…
- Trial name
- COSEFDIP (NCT05755659)
- Testing
- Fosaprepitant Dimeglumine for Injection
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Xijing Hospital
Adjuvant Treatment
Adjuvant Treatment of Digestive Tract Tumors
To evaluate the 3-year Disease-free survival rate(DFSR) of patients with locally advanced gastric cancer and colorectal cancer treated with anlotinib combined with adjuvant chemotherapy.
- Trial name
- ATDTT (NCT05742620)
- Testing
- anlotinib+CAPEOX/SOX
- Volunteers
- 100 people
- Sponsor
- Xijing Hospital
Esophageal Neoplasms, Pneumonia
Analysis of Risk Factors of Postoperative Pulmonary Infection in Patients With Esophageal Cancer
The goal of this observational study is to learn about in describe participant population. The main questions it aims to answer are: What are the risk factors of postoperative pulmonary infection in patients with esophageal…
- Trial name
- NCT05740852
- Volunteers
- 1,688 people
- Sponsor
- Xijing Hospital
Coronavirus Covid-19 Infection Variant Omicron, SARS (Severe Acute Respiratory Syndrome)
Nitric Oxide Gas Inhalation for Severe Acute Respiratory Syndrome in COVID-19.
The investigators will enroll 104 patients with severe COVID-19 infection that mechanical ventilation is needed for respiratory support.
- Trial name
- NOSARSCOVID (NCT04290871)
- Testing
- Nitric Oxide Gas, The delivery system will be set up anyway without study gas administration
- Sponsor
- Xijing Hospital