Clinical trials: sponsored by Xijing Hospital
Gastrointestinal Surgery
Patient-controlled Intravenous Analgesia Combined With Different Opioid Receptors for Gastrointestinal Surgery
Objective To evaluate the effect of patient-controlled intravenous analgesia combined with different opioid receptors for gastrointestinal surgery.
- Trial name
- NCT05576675
- Testing
- sufentanil + nalbuphine, Sufentanil, hydromorphone + nalbuphine
- Where
- China
- Volunteers
- 4,342 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Disorders of Consciousness
Brain Network Characteristics in Patients With Disorders of Consciousness
Simultaneous measurement of the three modalities, functional magnetic resonance imaging (fMRI), positron emission tomography (PET) and electroencephalography (EEG) was proven to be feasible and advantageous in evaluating brain…
- Trial name
- NCT05558670
- Testing
- PET-fMRI-EEG
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Xijing Hospital
Disorder of Consciousness, Vegetative State
Cerebellar iTBS in Patients With Disorders of Consciousness
Previous studies showed the excitatory effect of cerebellar transcranial magnetic stimulation(TMS) on motor cortex.Investigator evaluate the effects of bilateral cerebellar TMS on Coma Recovery Scale-Revised (CRS-R) scores in…
- Conditions
- Disorder of Consciousness, Vegetative State, Minimally Conscious State
- Trial name
- CTPDOC (NCT05558930)
- Testing
- iTBS stimulation
- Where
- China
- Volunteers
- 44 people
- Sponsor
- Xijing Hospital
Colorectal Cancer
A Small-sample, Real-world Study of Sintilimab Plus Bevacizumab/Cetuximab Plus XELOX Regimen for Conversion Therapy in Patients With Advanced Colorectal Cancer
The purpose of this study is to acssess the efficacy and the safety of Sintilimab plus bevacizumab/cetuximab plus XELOX regimen for conversion therapy in patients with advanced colorectal cancer
- Trial name
- NCT05544812
- Testing
- Sintilimab ，bevcizumab/cetuximab，XELOX
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Xijing Hospital
Melanoma
Interferon-α1b Combined With Toripalimab and Anlotinib Hydrochloride in Advanced Unresectable Melanoma
The purpose of this study is to evaluate the efficacy and safety of recombinant human interferon-α1b (IFN-α1b) combined with toripalimab and anlotinib hydrochloride in patients with unresectable advanced melanoma.
- Trial name
- NCT05539118
- Testing
- Recombinant human interferon α1b, Toripalimab, Anlotinib hydrochloride
- Where
- China
- Volunteers
- 48 people
- Sponsor
- Xijing Hospital
Cardiac Tumors
Cardiac Tumors Interventional （Radio Frequency/Laser Ablation）Therapy
Currently, surgical removal remains the main clinical treatment for cardiac tumor patients. However, part of tumors are hard to completely resect.
- Trial name
- CTIH (NCT02815553)
- Testing
- Direct Transthoracic Cardiac Tumor Radio Frequency Ablation Therapy, Direct Transthoracic Cardiac Tumor Laser Ablation Therapy
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Xijing Hospital
Colorectal Adenomas
A Research of Berberine Hydrochloride to Prevent Colorectal Adenomas in Patients With Previous Colorectal Cancer
Experimental studies in animals and observational studies in humans suggest that fusobacterium nucleatum is associates with stages of colorectal neoplasia development, and Berberine Hydrochloride could rescue Fusobacterium…
- Trial name
- NCT03281096
- Testing
- Berberine hydrochloride
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Colorectal Adenomas
Primary Chemoprevention of Familial Adenomatous Polyposis With Berberine Hydrochloride
In recent years, Berberine hydrochloride has been reported to inhibit cancer cell proliferation and to be cytotoxic towards cancer cells.
- Trial name
- NCT03333265
- Testing
- 100mg Berberine hydrochloride, 300mg Berberine hydrochloride
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Tinnitus, Subjective
The Study of Wuling Capsule in Treatment Chronic Tinnitus
To evaluate the effect of psychological/mental factors on the severity of subjective tinnitus, to observe the efficacy and safety of Wuling capsule in the treatment of chronic subjective tinnitus with emotional disorders, and to…
- Trial name
- NCT03674853
- Testing
- Wuling Capsule, Oryzanol
- Where
- China
- Volunteers
- 59 people
- Sponsor
- Xijing Hospital
99mTc-FAPI-positive Gastrointestinal Tumor
Comparative Study of 99mTc-FAPI SPECT/CT and 68Ga-FAPI PET/CT
The purpose of this study is to compare the similarities and differences of 99mTc-FAPI quantitative SPECT/CT and 68Ga-FAPI PET/CT in the diagnosis and staging of gastrointestinal tumors, and clinical diagnosis and economic value…
- Trial name
- NCT05444686
- Testing
- 99mTc-FAPI
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Head and Neck Squamous Cell Carcinoma
Nimotuzumab Combined With Neoadjuvant Chemotherapy in the Treatment of Resectable LA HNSCC
This study is a prospective, open-label, single-arm study. The trial will be divided into 3 phases: screening/baseline, treatment and follow-up.
- Trial name
- NCT05351762
- Testing
- Nimotuzumab Combined With Neoadjuvant Chemotherapy
- Volunteers
- 55 people
- Sponsor
- Xijing Hospital
Diabetes Mellitus, Spinal Diseases
A Clinical Study on the Effect of Hypoglycemic Drugs on the Prognosis of Spinal Surgery in Diabetic Patients
Diabetes mellitus is a group of metabolic diseases caused by multiple etiologies and characterized by chronic hyperglycemia. It seriously harms human health and has become a global public health challenge.
- Trial name
- NCT05214235
- Testing
- Hypoglycemic Drugs
- Where
- China
- Volunteers
- 124 people
- Sponsor
- Xijing Hospital
HER2-positive Breast Cancer and Gastric Cancer
Clinical Study of 68Ga Labeled HER2 Affibody Analogues
The purpose of this study is to assess the dosimetric properties of the positron emission tomography (PET) imaging probe 68Ga labeled HER2 Affibody analogues and preliminarily evaluate its diagnosis value in patients with breast…
- Trial name
- NCT05411432
- Testing
- 68Ga labeled HER2 Affibody
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Acute Ischemic Stroke
Predictive Study of Serum Endocan for Hemorrhagic Transformation After Reperfusion Therapies in Acute Ischemic Stroke
Stroke is the second largest cause of death globally after ischemic heart disease.Of the total number of prevalent strokes, 84.4% are ischemic.
- Trial name
- NCT05228080
- Testing
- enzyme-linked immunosorbent assay(ELISA)
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Disorder of Consciousness
A Promising Tool for Predicting Consciousness Evolution in Prolonged Disorders of Consciousness
The research contains two parts. Part 1: To explore whether EEG responses to zolpidem can assess consciousness circuit integrity and predict the evolution of consciousness in patients with prolonged disorders of consciousness…
- Trial name
- NCT02948660
- Testing
- Zolpidem Tartrate Tablets
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Gut Microbiota, microRNA
Human Gut Microbiota and microRNA Expression
In this study, stachyose was used as an intervention factor. We will evaluate changes in fecal gut microbiota and miRNA expression profiles in subjects under stachyose intervention
- Trial name
- NCT05392348
- Testing
- stachyose, Maltodextrin
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Gastric Cancer
Immune Combined Targeted and Chemotherapy in Perioperative Treatment of Locally Advanced Gastric Cancer
An exploratory study of pembrolizumab combined with anlotinib and chemotherapy in the perioperative treatment of locally advanced gastric cancer
- Trial name
- ICTCPTLAGC (NCT05385900)
- Testing
- Penpulimab combination with anlotinib and chemotherapy
- Volunteers
- 57 people
- Sponsor
- Xijing Hospital
Breast Cancer, HER2-positive Breast Cancer
PLD-cyclophosphamide-Nab-P Continuously Combined With Dual HER2 Blockage for HER2-positive Breast Cancer
patients with HER2-positive breast cancer (cT2-3/N0-1/M0) were treated with PldCHP (pegylated liposomal doxorubicin 35mg/m2, cyclophosphamide 600mg/m2, trastuzumab 8 mg/kg loading, then 6 mg/kg, pertuzumab 840 mg loading, then…
- Trial name
- NCT05346107
- Testing
- pegylated liposomal doxorubicin (PLD) plus cyclophosphamide followed by Nab-paclitaxel (Nab-P) ,continuously combined with dual HER2 blockage
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Xijing Hospital
Epileptic Seizures Related to Drugs, SARS-CoV-2 Acute Respiratory Disease
Epileptic Seizure in Epilepsy Patients After SARS-CoV-2 Vaccination
Background and Objectives: Seizure attack is one of adverse effects of vaccination in epileptic patients, the risk of which after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) inoculation was elucidated in the…
- Conditions
- Epileptic Seizures Related to Drugs, SARS-CoV-2 Acute Respiratory Disease, Vaccine Adverse Reaction
- Trial name
- NCT05341713
- Testing
- inactive SARS-Cov-2 vaccine
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Xijing Hospital
Intracerebral Hemorrhage
Glibenclamide Advantage in Treating Edema After Intracerebral Hemorrhage
The purpose of the present study is to explore the efficacy of small doses of oral glibenclamide on brain edema after acute primary intracerebral hemorrhage (ICH), and improving the prognosis of patients.
- Trial name
- GATE-ICH (NCT03741530)
- Testing
- Glibenclamide Tablets, Standard management for ICH
- Where
- 5 sites in China
- Volunteers
- 220 people
- Sponsor
- Xijing Hospital